ES2138668T3 - Nuevos derivados de peptidos terapeuticamente activos en la cadena de coagulacion sanguinea, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. - Google Patents

Nuevos derivados de peptidos terapeuticamente activos en la cadena de coagulacion sanguinea, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Info

Publication number
ES2138668T3
ES2138668T3 ES94929585T ES94929585T ES2138668T3 ES 2138668 T3 ES2138668 T3 ES 2138668T3 ES 94929585 T ES94929585 T ES 94929585T ES 94929585 T ES94929585 T ES 94929585T ES 2138668 T3 ES2138668 T3 ES 2138668T3
Authority
ES
Spain
Prior art keywords
contain
pharmaceutical compositions
blood coagulation
therapeutically active
preparation procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94929585T
Other languages
English (en)
Inventor
Jean-Luc Fauchere
Christophe Thurieau
Tony Verbeuren
Alain Rupin
Serge Simonet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of ES2138668T3 publication Critical patent/ES2138668T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA INVENCION SE REFIERE A LOS DERIVADOS DE FORMULA (I): H-PHE, A{SUB,1}-ARG-PRO-(GLY){SUB,4}-ASN-GLY-ASP-PHE-GLU-ABO-ILE-PROGLU-GLU-A{SUB,2}-LEU-GLU-OH, EN LA QUE A{SUB,1} Y A{SUB,2} SON TAL COMO SE DEFINEN EN LA DESCRIPCION. MEDICAMENTOS.
ES94929585T 1993-10-07 1994-10-06 Nuevos derivados de peptidos terapeuticamente activos en la cadena de coagulacion sanguinea, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. Expired - Lifetime ES2138668T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9311942A FR2710917B1 (fr) 1993-10-07 1993-10-07 Nouveaux dérivés de peptides thérapeutiquement actifs dans la cascade de coagulation sanguine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
ES2138668T3 true ES2138668T3 (es) 2000-01-16

Family

ID=9451616

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94929585T Expired - Lifetime ES2138668T3 (es) 1993-10-07 1994-10-06 Nuevos derivados de peptidos terapeuticamente activos en la cadena de coagulacion sanguinea, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Country Status (16)

Country Link
US (1) US5786330A (es)
EP (1) EP0722460B1 (es)
JP (1) JP2899415B2 (es)
CN (1) CN1053451C (es)
AT (1) ATE184287T1 (es)
AU (1) AU680696B2 (es)
CA (1) CA2173598A1 (es)
DE (1) DE69420574T2 (es)
DK (1) DK0722460T3 (es)
ES (1) ES2138668T3 (es)
FI (1) FI961505A (es)
FR (1) FR2710917B1 (es)
GR (1) GR3031254T3 (es)
NO (1) NO961357L (es)
NZ (1) NZ274524A (es)
WO (1) WO1995009869A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2340461A1 (en) * 2000-03-30 2001-09-30 University Of Manitoba Hirulog-like peptide and gene therapy
USRE46830E1 (en) 2004-10-19 2018-05-08 Polypeptide Laboratories Holding (Ppl) Ab Method for solid phase peptide synthesis
US7598343B1 (en) 2008-07-27 2009-10-06 The Medicines Company Pharmaceutical formulations of bivalirudin and processes of making the same
US7582727B1 (en) 2008-07-27 2009-09-01 The Medicinces Company Pharmaceutical formulations of bivalirudin and processes of making the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686086A1 (fr) * 1992-01-15 1993-07-16 Adir Nouveaux derives de peptides et de pseudopeptides therapeutiquement actifs dans la cascade de coagulation sanguine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
FR2710917B1 (fr) 1995-11-24
CN1053451C (zh) 2000-06-14
CN1134706A (zh) 1996-10-30
JPH09503221A (ja) 1997-03-31
EP0722460B1 (fr) 1999-09-08
FI961505A0 (fi) 1996-04-03
NO961357L (no) 1996-06-06
GR3031254T3 (en) 1999-12-31
NZ274524A (en) 1996-12-20
CA2173598A1 (fr) 1995-04-13
FR2710917A1 (fr) 1995-04-14
EP0722460A1 (fr) 1996-07-24
DE69420574D1 (de) 1999-10-14
AU7858794A (en) 1995-05-01
FI961505A (fi) 1996-04-03
US5786330A (en) 1998-07-28
JP2899415B2 (ja) 1999-06-02
NO961357D0 (no) 1996-04-02
ATE184287T1 (de) 1999-09-15
DK0722460T3 (da) 2000-03-20
WO1995009869A1 (fr) 1995-04-13
DE69420574T2 (de) 2000-05-04
AU680696B2 (en) 1997-08-07

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