HUP9903369A2 - 8(9)-Dehidroösztradiol-származékok - Google Patents

8(9)-Dehidroösztradiol-származékok

Info

Publication number
HUP9903369A2
HUP9903369A2 HU9903369A HUP9903369A HUP9903369A2 HU P9903369 A2 HUP9903369 A2 HU P9903369A2 HU 9903369 A HU9903369 A HU 9903369A HU P9903369 A HUP9903369 A HU P9903369A HU P9903369 A2 HUP9903369 A2 HU P9903369A2
Authority
HU
Hungary
Prior art keywords
dehydroestradiol
compounds
formula
derivatives
dehydroestradiol derivatives
Prior art date
Application number
HU9903369A
Other languages
English (en)
Inventor
Steven Jay Adelman
Frederick James Bex
Appavu Chandrasekaran
Dorothy Helen Prozialeck
Panolil Raveendranath
Michael William Winkley
Original Assignee
American Home Products Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp. filed Critical American Home Products Corp.
Publication of HUP9903369A2 publication Critical patent/HUP9903369A2/hu
Publication of HUP9903369A3 publication Critical patent/HUP9903369A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0062—Estrane derivatives substituted in position 17 alfa not substituted in position 17 beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány (I) képletű 17a, D8, 9-dehidroösztradiolra, (II) képletű17<, D8, 9-dehidroösztradiolra, valamint e vegyületek 3-szulfátésztereinek gyógyászati szempontból elfogadható sóiravonatkozik. A találmány tárgyát képezik e vegyületek előállításieljárásai, valamint gyógyászati készítmények, amelyek hatóanyagkéntilyen vegyületeket tartalmaznak. Ó
HU9903369A 1996-10-11 1997-10-09 8(9)-dehydroestradiol derivatives HUP9903369A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2793696P 1996-10-11 1996-10-11
PCT/US1997/018306 WO1998016544A1 (en) 1996-10-11 1997-10-09 8(9)-dehydroestradiol derivatives

Publications (2)

Publication Number Publication Date
HUP9903369A2 true HUP9903369A2 (hu) 2001-06-28
HUP9903369A3 HUP9903369A3 (en) 2002-02-28

Family

ID=21840614

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9903369A HUP9903369A3 (en) 1996-10-11 1997-10-09 8(9)-dehydroestradiol derivatives

Country Status (13)

Country Link
EP (1) EP0934334A1 (hu)
JP (1) JP2001502328A (hu)
KR (1) KR20000049055A (hu)
CN (1) CN1239967A (hu)
AR (1) AR014096A1 (hu)
AU (1) AU743530B2 (hu)
BR (1) BR9712628A (hu)
CA (1) CA2268330A1 (hu)
HU (1) HUP9903369A3 (hu)
IL (1) IL129029A0 (hu)
NZ (1) NZ335183A (hu)
WO (1) WO1998016544A1 (hu)
ZA (1) ZA979069B (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020173499A1 (en) * 2001-03-16 2002-11-21 Wyeth Estrogen replacement therapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES341947A1 (es) * 1966-06-21 1968-08-01 American Home Prod Un procedimiento para preparar compuestos esteroides.
SU286675A1 (ru) * 1969-01-10 1973-08-10 Институт химии природных соединений СССР СПОСОБ ПОЛУЧЕНИЯ dl-ЭСТРАДИОЛАйСС-СОЮЗНАЯfi^iffiTau-:::X:.:f-lAfiБИБЛИОТЕКА
FR2136891A1 (en) * 1971-05-07 1972-12-29 Inst Khim Prirodny Racemic estra-3,17 beta-diol prepn - steroid hormones
US5210081A (en) * 1992-02-26 1993-05-11 American Home Products Corporation Alkali metal 8,9-dehydroestrone sulfate esters
DE4338314C1 (de) * 1993-11-10 1995-03-30 Jenapharm Gmbh Pharmazeutische Präparate zur Prophylaxe und Therapie radikalvermittelter Zellschädigungen

Also Published As

Publication number Publication date
HUP9903369A3 (en) 2002-02-28
CN1239967A (zh) 1999-12-29
AU743530B2 (en) 2002-01-31
ZA979069B (en) 1999-04-09
BR9712628A (pt) 1999-10-26
IL129029A0 (en) 2000-02-17
AU5145998A (en) 1998-05-11
CA2268330A1 (en) 1998-04-23
NZ335183A (en) 2000-09-29
KR20000049055A (ko) 2000-07-25
EP0934334A1 (en) 1999-08-11
AR014096A1 (es) 2001-02-07
WO1998016544A1 (en) 1998-04-23
JP2001502328A (ja) 2001-02-20

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