AP9801417A0 - Piperidine acetic acid derivatives and their use in the treatment of thrombotic disorders. - Google Patents

Piperidine acetic acid derivatives and their use in the treatment of thrombotic disorders.

Info

Publication number
AP9801417A0
AP9801417A0 APAP/P/1998/001417A AP9801417A AP9801417A0 AP 9801417 A0 AP9801417 A0 AP 9801417A0 AP 9801417 A AP9801417 A AP 9801417A AP 9801417 A0 AP9801417 A0 AP 9801417A0
Authority
AP
ARIPO
Prior art keywords
treatment
acetic acid
thrombotic disorders
acid derivatives
piperidine acetic
Prior art date
Application number
APAP/P/1998/001417A
Inventor
David George Allen
Colin David Eldred
Brian David Judkins
William Leornard Mitchell
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9613017.4A external-priority patent/GB9613017D0/en
Priority claimed from GBGB9613095.0A external-priority patent/GB9613095D0/en
Priority claimed from GBGB9613018.2A external-priority patent/GB9613018D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AP9801417A0 publication Critical patent/AP9801417A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention relates to compounds of formula (i)or a salt, solvate, or physiologically functionalj derivative thereof, in which x represents either ch2-ch2-ch2 or ch-ch; y represents a group (a)or (b); r0 represents so2me or conh2, and r1 represents so2me, to processes for their preparation, to pharmaceutical compositions containing such compounds and to their use in medicine, particularly in the treatment of thrombotic disorders.
APAP/P/1998/001417A 1996-06-21 1997-06-19 Piperidine acetic acid derivatives and their use in the treatment of thrombotic disorders. AP9801417A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9613017.4A GB9613017D0 (en) 1996-06-21 1996-06-21 Therapeutic compounds
GBGB9613095.0A GB9613095D0 (en) 1996-06-21 1996-06-21 Therapeutic piperidines
GBGB9613018.2A GB9613018D0 (en) 1996-06-21 1996-06-21 Therapeutic indazoles
PCT/EP1997/003196 WO1997049699A1 (en) 1996-06-21 1997-06-19 Piperidine acetic acid derivatives and their use in the treatment of thrombotic disorders

Publications (1)

Publication Number Publication Date
AP9801417A0 true AP9801417A0 (en) 1998-12-31

Family

ID=27268341

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1998/001417A AP9801417A0 (en) 1996-06-21 1997-06-19 Piperidine acetic acid derivatives and their use in the treatment of thrombotic disorders.

Country Status (17)

Country Link
EP (1) EP0912555A1 (en)
JP (1) JP2000512648A (en)
KR (1) KR20000022041A (en)
AP (1) AP9801417A0 (en)
AR (1) AR008245A1 (en)
AU (1) AU3261197A (en)
BR (1) BR9709930A (en)
CA (1) CA2258753A1 (en)
CZ (1) CZ424698A3 (en)
EA (1) EA199801015A1 (en)
ID (1) ID17052A (en)
IL (1) IL127464A0 (en)
IS (1) IS4924A (en)
NO (1) NO985974L (en)
PL (1) PL330797A1 (en)
TR (1) TR199802665T2 (en)
WO (1) WO1997049699A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1401831A1 (en) 2001-07-03 2004-03-31 Chiron Corporation Indazole benzimidazole compounds as tyrosine and serine/threonine kinase inhibitors
US7642278B2 (en) 2001-07-03 2010-01-05 Novartis Vaccines And Diagnostics, Inc. Indazole benzimidazole compounds
TW200401641A (en) 2002-07-18 2004-02-01 Wyeth Corp 1-Heterocyclylalkyl-3-sulfonylindole or-indazole derivatives as 5-hydroxytryptamine-6 ligands
RU2347780C2 (en) * 2003-02-14 2009-02-27 Уайт Heterocyclyl-3-sulfonylindazoles as 5-hyroxytryptamine-6 ligands
AU2007235499A1 (en) 2006-04-05 2007-10-18 Wyeth Sulfonyl-3-heterocyclylindazole derivatives as 5-hydroxytryptamine-6 ligands
BRPI0806542A2 (en) 2007-01-10 2014-04-22 Hoffmann La Roche SULFONAMIDE DERIVATIVES AS CHEMASE INHIBITORS
CN113655155A (en) * 2021-07-28 2021-11-16 任贤金 Method for measuring SPH3127 related substances

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4124942A1 (en) * 1991-07-27 1993-01-28 Thomae Gmbh Dr K 5-LOW HETEROCYCLES, METHOD FOR THE PRODUCTION THEREOF AND MEDICAMENTS CONTAINING SUCH COMPOUNDS
AU2915892A (en) * 1991-11-14 1993-06-15 Glaxo Group Limited Piperidine acetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation
GB9208740D0 (en) * 1992-04-23 1992-06-10 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
ID17052A (en) 1997-12-04
KR20000022041A (en) 2000-04-25
NO985974D0 (en) 1998-12-18
EP0912555A1 (en) 1999-05-06
NO985974L (en) 1999-02-17
PL330797A1 (en) 1999-06-07
BR9709930A (en) 1999-08-10
IL127464A0 (en) 1999-10-28
IS4924A (en) 1998-12-15
WO1997049699A1 (en) 1997-12-31
CA2258753A1 (en) 1997-12-31
TR199802665T2 (en) 1999-03-22
JP2000512648A (en) 2000-09-26
AU3261197A (en) 1998-01-14
EA199801015A1 (en) 1999-08-26
CZ424698A3 (en) 1999-05-12
AR008245A1 (en) 1999-12-29

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