NO985974L - Piperidinedacetic acid derivatives and their use in the treatment of thrombosis diseases - Google Patents

Piperidinedacetic acid derivatives and their use in the treatment of thrombosis diseases

Info

Publication number
NO985974L
NO985974L NO985974A NO985974A NO985974L NO 985974 L NO985974 L NO 985974L NO 985974 A NO985974 A NO 985974A NO 985974 A NO985974 A NO 985974A NO 985974 L NO985974 L NO 985974L
Authority
NO
Norway
Prior art keywords
treatment
piperidinedacetic
acid derivatives
diseases
thrombosis diseases
Prior art date
Application number
NO985974A
Other languages
Norwegian (no)
Other versions
NO985974D0 (en
Inventor
David George Allen
Colin David Eldred
Brian David Judkins
William Leonard Mitchell
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9613018.2A external-priority patent/GB9613018D0/en
Priority claimed from GBGB9613017.4A external-priority patent/GB9613017D0/en
Priority claimed from GBGB9613095.0A external-priority patent/GB9613095D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO985974D0 publication Critical patent/NO985974D0/en
Publication of NO985974L publication Critical patent/NO985974L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Foreliggende oppfinnelse angår forbindelser med formel (I) eller et av deres salter, solvater eller fysiologisk funksjonelle derivater hvor X er enten CH2-CH2 eller CH=CH; X er en gruppe (a) eller (b); R° er SO2Me eller CONH2, og R1 er S02Me, fremgangsmåter for deres fremstilling, farmasøytiske blandinger eller pre- parater som inneholder slike forbindelser samt deres anvendelse i medisin, spesi- elt for behandling av tromboselidelser eller -sykdommer.The present invention relates to compounds of formula (I) or one of their salts, solvates or physiologically functional derivatives wherein X is either CH 2 -CH 2 or CH = CH; X is a group (a) or (b); R 2 is SO 2 Me or CONH 2 and R 1 is SO 2 Me, processes for their preparation, pharmaceutical compositions or preparations containing such compounds and their use in medicine, especially for the treatment of thrombosis disorders or diseases.

NO985974A 1996-06-21 1998-12-18 Piperidinedacetic acid derivatives and their use in the treatment of thrombosis diseases NO985974L (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9613018.2A GB9613018D0 (en) 1996-06-21 1996-06-21 Therapeutic indazoles
GBGB9613017.4A GB9613017D0 (en) 1996-06-21 1996-06-21 Therapeutic compounds
GBGB9613095.0A GB9613095D0 (en) 1996-06-21 1996-06-21 Therapeutic piperidines
GB9703196 1997-06-19

Publications (2)

Publication Number Publication Date
NO985974D0 NO985974D0 (en) 1998-12-18
NO985974L true NO985974L (en) 1999-02-17

Family

ID=27268341

Family Applications (1)

Application Number Title Priority Date Filing Date
NO985974A NO985974L (en) 1996-06-21 1998-12-18 Piperidinedacetic acid derivatives and their use in the treatment of thrombosis diseases

Country Status (17)

Country Link
EP (1) EP0912555A1 (en)
JP (1) JP2000512648A (en)
KR (1) KR20000022041A (en)
AP (1) AP9801417A0 (en)
AR (1) AR008245A1 (en)
AU (1) AU3261197A (en)
BR (1) BR9709930A (en)
CA (1) CA2258753A1 (en)
CZ (1) CZ424698A3 (en)
EA (1) EA199801015A1 (en)
ID (1) ID17052A (en)
IL (1) IL127464A0 (en)
IS (1) IS4924A (en)
NO (1) NO985974L (en)
PL (1) PL330797A1 (en)
TR (1) TR199802665T2 (en)
WO (1) WO1997049699A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7642278B2 (en) 2001-07-03 2010-01-05 Novartis Vaccines And Diagnostics, Inc. Indazole benzimidazole compounds
EP1401831A1 (en) 2001-07-03 2004-03-31 Chiron Corporation Indazole benzimidazole compounds as tyrosine and serine/threonine kinase inhibitors
TW200401641A (en) 2002-07-18 2004-02-01 Wyeth Corp 1-Heterocyclylalkyl-3-sulfonylindole or-indazole derivatives as 5-hydroxytryptamine-6 ligands
KR20050101551A (en) 2003-02-14 2005-10-24 와이어쓰 Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands
JP2009532471A (en) 2006-04-05 2009-09-10 ワイス Sulfonyl-3-heterocyclylindazole derivatives as 5-hydroxytryptamine-6 ligands
BRPI0806542A2 (en) 2007-01-10 2014-04-22 Hoffmann La Roche SULFONAMIDE DERIVATIVES AS CHEMASE INHIBITORS
CN113655155A (en) * 2021-07-28 2021-11-16 任贤金 Method for measuring SPH3127 related substances

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4124942A1 (en) * 1991-07-27 1993-01-28 Thomae Gmbh Dr K 5-LOW HETEROCYCLES, METHOD FOR THE PRODUCTION THEREOF AND MEDICAMENTS CONTAINING SUCH COMPOUNDS
AU2915892A (en) * 1991-11-14 1993-06-15 Glaxo Group Limited Piperidine acetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation
GB9208740D0 (en) * 1992-04-23 1992-06-10 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
PL330797A1 (en) 1999-06-07
ID17052A (en) 1997-12-04
JP2000512648A (en) 2000-09-26
BR9709930A (en) 1999-08-10
NO985974D0 (en) 1998-12-18
CZ424698A3 (en) 1999-05-12
IL127464A0 (en) 1999-10-28
CA2258753A1 (en) 1997-12-31
IS4924A (en) 1998-12-15
EP0912555A1 (en) 1999-05-06
AU3261197A (en) 1998-01-14
WO1997049699A1 (en) 1997-12-31
KR20000022041A (en) 2000-04-25
AR008245A1 (en) 1999-12-29
AP9801417A0 (en) 1998-12-31
EA199801015A1 (en) 1999-08-26
TR199802665T2 (en) 1999-03-22

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application