JP2001502328A - ８（９）―デヒドロエストラジオール誘導体 - Google Patents

８（９）―デヒドロエストラジオール誘導体

Info

Publication number
JP2001502328A
JP2001502328A JP10518462A JP51846298A JP2001502328A JP 2001502328 A JP2001502328 A JP 2001502328A JP 10518462 A JP10518462 A JP 10518462A JP 51846298 A JP51846298 A JP 51846298A JP 2001502328 A JP2001502328 A JP 2001502328A
Authority
JP
Japan
Prior art keywords
dehydroestradiol
sulfate
pharmaceutically acceptable
acceptable salt
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10518462A
Other languages
English (en)
Japanese (ja)
Inventor
エイデルマン，スティーブン・ジェイ
ベックス，フレデリック・ジェイムズ
チャンドラセカラン，アパブ
プロジアレック，ドロシー・ヘレン
ウィンクリー，マイケル・ウィリアム
ラビーンドラナス，パノリル
Original Assignee
アメリカン・ホーム・プロダクツ・コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アメリカン・ホーム・プロダクツ・コーポレイション filed Critical アメリカン・ホーム・プロダクツ・コーポレイション
Publication of JP2001502328A publication Critical patent/JP2001502328A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0062—Estrane derivatives substituted in position 17 alfa not substituted in position 17 beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP10518462A 1996-10-11 1997-10-09 ８（９）―デヒドロエストラジオール誘導体 Pending JP2001502328A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2793696P 1996-10-11 1996-10-11
US60/027,936 1996-10-11
PCT/US1997/018306 WO1998016544A1 (en) 1996-10-11 1997-10-09 8(9)-dehydroestradiol derivatives

Publications (1)

Publication Number Publication Date
JP2001502328A true JP2001502328A (ja) 2001-02-20

Family

ID=21840614

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10518462A Pending JP2001502328A (ja) 1996-10-11 1997-10-09 ８（９）―デヒドロエストラジオール誘導体

Country Status (13)

Country Link
EP (1) EP0934334A1 (hu)
JP (1) JP2001502328A (hu)
KR (1) KR20000049055A (hu)
CN (1) CN1239967A (hu)
AR (1) AR014096A1 (hu)
AU (1) AU743530B2 (hu)
BR (1) BR9712628A (hu)
CA (1) CA2268330A1 (hu)
HU (1) HUP9903369A3 (hu)
IL (1) IL129029A0 (hu)
NZ (1) NZ335183A (hu)
WO (1) WO1998016544A1 (hu)
ZA (1) ZA979069B (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020173499A1 (en) * 2001-03-16 2002-11-21 Wyeth Estrogen replacement therapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES341947A1 (es) * 1966-06-21 1968-08-01 American Home Prod Un procedimiento para preparar compuestos esteroides.
SU286675A1 (ru) * 1969-01-10 1973-08-10 Институт химии природных соединений СССР СПОСОБ ПОЛУЧЕНИЯ dl-ЭСТРАДИОЛАйСС-СОЮЗНАЯfi^iffiTau-:::X:.:f-lAfiБИБЛИОТЕКА
FR2136891A1 (en) * 1971-05-07 1972-12-29 Inst Khim Prirodny Racemic estra-3,17 beta-diol prepn - steroid hormones
US5210081A (en) * 1992-02-26 1993-05-11 American Home Products Corporation Alkali metal 8,9-dehydroestrone sulfate esters
DE4338314C1 (de) * 1993-11-10 1995-03-30 Jenapharm Gmbh Pharmazeutische Präparate zur Prophylaxe und Therapie radikalvermittelter Zellschädigungen

Also Published As

Publication number Publication date
HUP9903369A3 (en) 2002-02-28
CN1239967A (zh) 1999-12-29
AU743530B2 (en) 2002-01-31
ZA979069B (en) 1999-04-09
BR9712628A (pt) 1999-10-26
IL129029A0 (en) 2000-02-17
AU5145998A (en) 1998-05-11
HUP9903369A2 (hu) 2001-06-28
CA2268330A1 (en) 1998-04-23
NZ335183A (en) 2000-09-29
KR20000049055A (ko) 2000-07-25
EP0934334A1 (en) 1999-08-11
AR014096A1 (es) 2001-02-07
WO1998016544A1 (en) 1998-04-23

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