GR3019326T3 - Cyclic vip analogs - Google Patents

Cyclic vip analogs

Info

Publication number
GR3019326T3
GR3019326T3 GR960400712T GR960400712T GR3019326T3 GR 3019326 T3 GR3019326 T3 GR 3019326T3 GR 960400712 T GR960400712 T GR 960400712T GR 960400712 T GR960400712 T GR 960400712T GR 3019326 T3 GR3019326 T3 GR 3019326T3
Authority
GR
Greece
Prior art keywords
peptide
amino acid
vasoactive
chain
cyclic
Prior art date
Application number
GR960400712T
Other languages
Greek (el)
English (en)
Inventor
David Robert Bolin
Margaret O'donnell
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of GR3019326T3 publication Critical patent/GR3019326T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/17—Vasoactive intestinal peptides; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GR960400712T 1991-10-11 1996-03-15 Cyclic vip analogs GR3019326T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77374791A 1991-10-11 1991-10-11

Publications (1)

Publication Number Publication Date
GR3019326T3 true GR3019326T3 (en) 1996-06-30

Family

ID=25099195

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960400712T GR3019326T3 (en) 1991-10-11 1996-03-15 Cyclic vip analogs

Country Status (26)

Country Link
US (1) US5677419A (enExample)
EP (1) EP0536741B1 (enExample)
JP (1) JP2515473B2 (enExample)
KR (1) KR970001580B1 (enExample)
CN (3) CN1034943C (enExample)
AT (1) ATE132165T1 (enExample)
AU (1) AU656230B2 (enExample)
BG (1) BG61125B2 (enExample)
BR (1) BR9203959A (enExample)
CA (1) CA2080272C (enExample)
CZ (1) CZ281818B6 (enExample)
DE (1) DE69207138T2 (enExample)
DK (1) DK0536741T3 (enExample)
ES (1) ES2082317T3 (enExample)
FI (2) FI111646B (enExample)
GR (1) GR3019326T3 (enExample)
HU (2) HUT62606A (enExample)
IL (3) IL103396A (enExample)
MX (1) MX9205822A (enExample)
NO (3) NO304523B1 (enExample)
NZ (1) NZ244644A (enExample)
RU (1) RU2095368C1 (enExample)
SK (1) SK279399B6 (enExample)
TW (1) TW305846B (enExample)
UY (2) UY23488A1 (enExample)
ZA (1) ZA927724B (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872803B1 (en) 1993-09-21 2005-03-29 Kyowa Hakko Kogyo Co., Ltd. Peptides
BR9707409A (pt) * 1996-02-09 1999-04-13 Waleed Danho Sintese de análogo de vip
ATE380038T1 (de) * 1996-07-12 2007-12-15 Immunomedics Inc Radiometall-bindende peptide analoge
WO1998002453A2 (en) * 1996-07-15 1998-01-22 Universite Libre De Bruxelles Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor
DE60039111D1 (de) * 1999-09-28 2008-07-17 Bayer Corp Agonisten des rezeptors 3 (r3) von pituitary adenylate cyclase aktivierendem peptid (pacap) und ihre pharmakologische verwendung
US6972319B1 (en) 1999-09-28 2005-12-06 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
AU2000265051A1 (en) * 2000-02-18 2001-08-27 Dabur Research Foundation Vasoactive intestinal peptide analogs
DE60033697D1 (de) 2000-02-18 2007-04-12 Dabur Res Foundation Sahibabad Radiomarkierte vip-analoge zur diagnose und therapie
US6828304B1 (en) 2000-07-31 2004-12-07 Dabur Research Foundation Peptides for treatment of cancer
US7507714B2 (en) * 2000-09-27 2009-03-24 Bayer Corporation Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
WO2002043746A2 (en) 2000-11-28 2002-06-06 Mondobiotech Sa Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension
JP2005535607A (ja) 2002-06-10 2005-11-24 モンドバイオテック・ラボラトリーズ・アンスタルト サルコイドーシスを治療するための血管作動性腸管ペプチドの生物活性をもつ化合物の使用
JP2007519739A (ja) * 2004-01-27 2007-07-19 バイエル・フアーマシユーチカルズ・コーポレーシヨン 下垂体細胞アデニル酸シクラーゼ活性化ペプチド（ｐａｃａｐ）受容体（ｖｃａｐ２）アゴニストおよびそれらの製薬学的使用方法
WO2006023367A1 (en) * 2004-08-18 2006-03-02 Eli Lilly And Company Selective vpac2 receptor peptide agonists
US20080085860A1 (en) * 2004-08-18 2008-04-10 Eli Lilly And Company Selective Vpac2 Receptor Peptide Agonists
RU2304146C2 (ru) * 2005-10-17 2007-08-10 Закрытое акционерное общество "Эпитек" Способ стабилизации петлеобразной структуры синтетических пептидов с помощью n- и c-концевых модификаций
JP2009528376A (ja) * 2006-02-28 2009-08-06 イーライ リリー アンド カンパニー 選択的ｖｐａｃ２受容体ペプチドアゴニスト
BRPI0714306A2 (pt) * 2006-07-06 2014-05-20 Hoffmann La Roche Análogos do peptídio intestinal vasoativo
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
IN2012DN02120A (enExample) 2009-08-14 2015-08-21 Phasebio Pharmaceuticals Inc
CA2797033C (en) 2010-04-22 2021-10-19 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
ES2669190T3 (es) 2011-06-06 2018-05-24 Phasebio Pharmaceuticals, Inc. Uso de péptidos intestinales vasoactivos modificados en el tratamiento de la hipertensión
WO2014145718A2 (en) 2013-03-15 2014-09-18 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
GB201421647D0 (en) * 2014-12-05 2015-01-21 Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
ES2822598T3 (es) 2015-02-09 2021-05-04 Phasebio Pharmaceuticals Inc Métodos y composiciones para tratar enfermedades y trastornos musculares
CA3036768A1 (en) 2016-09-30 2018-04-05 Fujifilm Corporation Cyclic peptide, affinity chromatography support, labeled antibody, antibody drug conjugate, and pharmaceutical preparation
IL295797A (en) * 2020-02-22 2022-10-01 Japan Chem Res Human transfer receptor binding peptide
WO2023026994A1 (ja) * 2021-08-21 2023-03-02 武田薬品工業株式会社 ヒトトランスフェリンレセプター結合ペプチド－薬物コンジュゲート

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
US4835252A (en) * 1987-02-26 1989-05-30 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
GB8729802D0 (en) * 1987-12-22 1988-02-03 Beecham Group Plc Novel compounds
US5084442A (en) * 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5141924A (en) * 1989-06-30 1992-08-25 Hoffmann-La Roche, Inc. Synthetic vasoactive intestinal peptide analogs

Also Published As

Publication number Publication date
NO923929D0 (no) 1992-10-09
EP0536741B1 (en) 1995-12-27
NO980377D0 (no) 1998-01-28
CA2080272A1 (en) 1993-04-12
IL117252A0 (en) 1996-06-18
ES2082317T3 (es) 1996-03-16
DE69207138T2 (de) 1996-06-13
HUT62606A (en) 1993-05-28
CN1198841C (zh) 2005-04-27
RU2095368C1 (ru) 1997-11-10
BG61125B2 (bg) 1996-11-29
HU211534A9 (en) 1995-12-28
DK0536741T3 (da) 1996-04-22
IL103396A0 (en) 1993-03-15
NO975023D0 (no) 1997-10-31
DE69207138D1 (de) 1996-02-08
EP0536741A2 (en) 1993-04-14
CN1153785A (zh) 1997-07-09
CN1225473C (zh) 2005-11-02
FI20002041L (fi) 2000-09-15
IL117252A (en) 1999-11-30
UY25084A1 (es) 1998-12-21
CN1152579A (zh) 1997-06-25
CA2080272C (en) 2002-09-17
IL103396A (en) 1997-11-20
UY23488A1 (es) 1993-04-20
TW305846B (enExample) 1997-05-21
KR970001580B1 (ko) 1997-02-11
NO975023L (no) 1993-04-13
SK308692A3 (en) 1995-03-08
FI924580A0 (fi) 1992-10-09
US5677419A (en) 1997-10-14
JPH05213996A (ja) 1993-08-24
NO304523B1 (no) 1999-01-04
SK279399B6 (sk) 1998-11-04
FI924580L (fi) 1993-04-12
CN1034943C (zh) 1997-05-21
NZ244644A (en) 1995-04-27
CN1072415A (zh) 1993-05-26
FI111646B (fi) 2003-08-29
CZ308692A3 (en) 1993-08-11
AU656230B2 (en) 1995-01-27
JP2515473B2 (ja) 1996-07-10
CZ281818B6 (cs) 1997-02-12
FI20002041A7 (fi) 2000-09-15
HU9203194D0 (en) 1992-12-28
EP0536741A3 (enExample) 1994-04-06
NO923929L (no) 1993-04-13
ATE132165T1 (de) 1996-01-15
AU2622892A (en) 1993-04-22
BR9203959A (pt) 1993-04-27
ZA927724B (en) 1994-04-07
NO980377L (no) 1993-04-13
MX9205822A (es) 1993-06-01
KR930007972A (ko) 1993-05-20

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