US6472147B1
(en)
*
|
1999-05-25 |
2002-10-29 |
The Scripps Research Institute |
Methods for display of heterodimeric proteins on filamentous phage using pVII and pIX, compositions, vectors and combinatorial libraries
|
WO2001023619A1
(en)
|
1999-09-29 |
2001-04-05 |
Xenoport, Inc. |
Compounds displayed on replicable genetic packages and methods of using same
|
US7037706B1
(en)
|
1999-09-29 |
2006-05-02 |
Xenoport, Inc. |
Compounds displayed on replicable genetic packages and methods of using same
|
US8288322B2
(en)
|
2000-04-17 |
2012-10-16 |
Dyax Corp. |
Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
|
ES2393535T3
(es)
*
|
2000-04-17 |
2012-12-26 |
Dyax Corp. |
Nuevos métodos para construir bibliotecas de paquetes genéticos que presentan de forma colectiva los miembros de una familia diversa de péptidos, polipéptidos o proteínas
|
AU2002249854B2
(en)
|
2000-12-18 |
2007-09-20 |
Dyax Corp. |
Focused libraries of genetic packages
|
EP1385984A4
(de)
*
|
2001-03-21 |
2007-06-13 |
Xenoport Inc |
Auf einem icosaedrischen phagen präsentierte verbindung und verfahren zu deren verwendung
|
US6833441B2
(en)
|
2001-08-01 |
2004-12-21 |
Abmaxis, Inc. |
Compositions and methods for generating chimeric heteromultimers
|
US7202045B2
(en)
*
|
2001-09-19 |
2007-04-10 |
Regents Of The University Of Michigan |
Detection and treatment of cancers of the lung
|
US7175983B2
(en)
*
|
2001-11-02 |
2007-02-13 |
Abmaxis, Inc. |
Adapter-directed display systems
|
AU2003253193B2
(en)
*
|
2002-07-30 |
2009-07-02 |
Morphosys Ag |
Novel tricistronic vectors and uses therefor
|
US20040067532A1
(en)
|
2002-08-12 |
2004-04-08 |
Genetastix Corporation |
High throughput generation and affinity maturation of humanized antibody
|
NZ570811A
(en)
|
2002-11-09 |
2009-11-27 |
Immunocore Ltd |
T cell receptor display
|
AU2004204095B2
(en)
|
2003-01-07 |
2009-07-30 |
Dyax Corporation |
Kunitz domain library
|
CA2555185C
(en)
|
2004-02-06 |
2020-03-24 |
Morphosys Ag |
Anti-cd38 human antibodies and uses therefor
|
US9200061B2
(en)
|
2004-02-06 |
2015-12-01 |
Morpho Sys AG |
Generation and profiling of fully human HuCAL gold®-derived therapeutic antibodies specific for human CD3i
|
SG142330A1
(en)
|
2004-02-06 |
2008-05-28 |
Morphosys Ag De |
Anti-cd38 human antibodies and uses therefor
|
WO2006125640A2
(en)
|
2005-05-24 |
2006-11-30 |
Morphosys Ag |
Generation and profiling of fully human hucal gold®-derived therapeutic antibodies specific for human cd38
|
EP1855723B1
(de)
*
|
2005-03-08 |
2013-05-22 |
Ramot at Tel-Aviv University Ltd. |
Zielgerichtete arzneistofftragende bakteriophagen
|
WO2006122797A2
(en)
|
2005-05-18 |
2006-11-23 |
Morphosys Ag |
Anti-gm-csf antibodies and uses therefor
|
US8114964B2
(en)
|
2005-05-19 |
2012-02-14 |
Centocor, Inc. |
Anti-MCP-1 antibodies, compositions, methods and uses
|
CN106434683B
(zh)
|
2005-10-12 |
2020-03-13 |
莫佛塞斯公司 |
特异性针对人CD38的完全人HuCAL GOLD-衍生治疗抗体的生成和鉴定
|
CN101356271A
(zh)
|
2005-11-09 |
2009-01-28 |
拜耳先灵医药股份有限公司 |
功能阻断性抗-ed-b-纤连蛋白抗体的鉴别与鉴定
|
DOP2006000277A
(es)
|
2005-12-12 |
2007-08-31 |
Bayer Pharmaceuticals Corp |
Anticuerpos anti mn y métodos para su utilización
|
MX2008008220A
(es)
*
|
2005-12-20 |
2009-03-04 |
Morphosys Ag |
Nueva coleccion de regiones hcdr3 y usos de las mismas.
|
CA2646048A1
(en)
|
2006-03-30 |
2007-11-08 |
Novartis Ag |
Compositions and methods of use for antibodies of c-met
|
EP2420832A1
(de)
|
2006-05-04 |
2012-02-22 |
Abmaxis, Inc. |
Artenübergreifende und Mehrartenanzeigesysteme
|
ES2372709T3
(es)
|
2006-07-05 |
2012-01-25 |
Catalyst Biosciences, Inc. |
Procedimientos de cribado de proteasas y proteasas identificadas por los mismos.
|
CN101558156B
(zh)
|
2006-12-12 |
2011-11-23 |
莫佛塞斯公司 |
内化
|
ES2403904T3
(es)
*
|
2007-08-21 |
2013-05-22 |
Morphosys Ag |
Métodos para la formación de enlaces disulfuro
|
NZ583966A
(en)
|
2007-08-30 |
2012-04-27 |
Daiichi Sankyo Co Ltd |
Anti-epha2 antibody
|
US8877688B2
(en)
*
|
2007-09-14 |
2014-11-04 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
DK3124497T3
(da)
|
2007-09-14 |
2020-05-11 |
Adimab Llc |
Rationelt designede syntetiske antistofbiblioteker og anvendelser deraf
|
AR068767A1
(es)
|
2007-10-12 |
2009-12-02 |
Novartis Ag |
Anticuerpos contra esclerostina, composiciones y metodos de uso de estos anticuerpos para tratar un trastorno patologico mediado por esclerostina
|
NZ585551A
(en)
|
2007-11-26 |
2012-06-29 |
Bayer Schering Pharma Ag |
Anti-mesothelin antibodies and uses therefor
|
PL2257624T3
(pl)
|
2008-02-05 |
2012-09-28 |
Medical Res Council |
Sposoby i kompozycje
|
US9873957B2
(en)
|
2008-03-13 |
2018-01-23 |
Dyax Corp. |
Libraries of genetic packages comprising novel HC CDR3 designs
|
US10485879B2
(en)
|
2008-04-15 |
2019-11-26 |
Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health |
Plasma cell cytokine vehicle containing fusion proteins for targeted introduction of siRNA into cells and tissues
|
CA2720363A1
(en)
|
2008-04-15 |
2009-10-22 |
Bira Arya |
Compositions and methods for delivering inhibitory oligonucleotides
|
JP5780951B2
(ja)
|
2008-04-24 |
2015-09-16 |
ダイアックス コーポレーション |
新規のhccdr1、cdr2、およびcdr3設計、ならびに新規のlccdr1、cdr2、およびcdr3設計を含む、遺伝子パッケージのライブラリ
|
EP2815766B1
(de)
|
2008-08-05 |
2017-07-05 |
Novartis AG |
Zusammensetzungen und Verfahren für auf das Komplementprotein C5 gerichtete Antikörper
|
WO2010028347A2
(en)
|
2008-09-05 |
2010-03-11 |
President & Fellows Of Harvard College |
Continuous directed evolution of proteins and nucleic acids
|
WO2010079189A1
(en)
|
2009-01-09 |
2010-07-15 |
Morphosys Ag |
Display vectors and methods and uses thereof
|
TWI480050B
(zh)
|
2009-02-10 |
2015-04-11 |
Daiichi Sankyo Co Ltd |
抗-mst1r抗體及其用途
|
EP3275900A1
(de)
|
2009-04-27 |
2018-01-31 |
Novartis AG |
Zusammensetzungen und verfahren zur förderung des muskelwachstums
|
MX2011011338A
(es)
|
2009-04-27 |
2012-04-19 |
Novartis Ag |
Composiciones y metodos de uso para anticuerpos terapeuticos especificos para la subunidad beta1 del receptor de il-12.
|
UY32560A
(es)
|
2009-04-29 |
2010-11-30 |
Bayer Schering Pharma Ag |
Inmunoconjugados de antimesotelina y usos de los mismos
|
NZ596058A
(en)
*
|
2009-04-30 |
2013-08-30 |
Cytos Biotechnology Ag |
Influenza hemagglutinin compositions and uses thereof
|
JP5804521B2
(ja)
|
2009-05-29 |
2015-11-04 |
モルフォシス・アー・ゲー |
コレクション及びその使用方法
|
WO2011021146A1
(en)
|
2009-08-20 |
2011-02-24 |
Pfizer Inc. |
Osteopontin antibodies
|
WO2011032181A2
(en)
*
|
2009-09-14 |
2011-03-17 |
Dyax Corp. |
Libraries of genetic packages comprising novel hc cdr3 designs
|
US20110189183A1
(en)
|
2009-09-18 |
2011-08-04 |
Robert Anthony Williamson |
Antibodies against candida, collections thereof and methods of use
|
JP5955773B2
(ja)
|
2009-11-17 |
2016-07-20 |
ヤンセン バイオテツク,インコーポレーテツド |
改善された細菌膜タンパク質分泌
|
WO2011062859A1
(en)
|
2009-11-17 |
2011-05-26 |
Centocor Ortho Biotech Inc. |
Display of disulfide linked dimeric proteins on filamentous phage
|
ES2551871T3
(es)
|
2010-01-29 |
2015-11-24 |
Morphosys Ag |
Genotecas combinatorias de anticuerpos de roedor
|
US9290573B2
(en)
|
2010-05-06 |
2016-03-22 |
Novartis Ag |
Therapeutic low density lipoprotein-related protein 6 (LRP6) multivalent antibodies
|
AU2011249783B9
(en)
|
2010-05-06 |
2014-11-06 |
Novartis Ag |
Compositions and methods of use for therapeutic low density lipoprotein -related protein 6 (LRP6) antibodies
|
JP6266343B2
(ja)
|
2010-07-16 |
2018-01-24 |
アディマブ, エルエルシー |
抗体ライブラリー
|
DK2606070T3
(en)
|
2010-08-20 |
2017-03-27 |
Novartis Ag |
Antibodies for the epidermal growth factor receptor 3 (HER3)
|
RU2551963C2
(ru)
|
2010-09-09 |
2015-06-10 |
Пфайзер Инк. |
Молекулы, связывающиеся с 4-1вв
|
JP2013543382A
(ja)
|
2010-10-05 |
2013-12-05 |
第一三共株式会社 |
破骨細胞関連蛋白質Siglec−15を標的とした抗体
|
MX353795B
(es)
|
2010-11-19 |
2018-01-30 |
Morphosys Ag |
Coleccion y metodos para su uso.
|
JP6088438B2
(ja)
|
2010-12-22 |
2017-03-01 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
連続的定向進化
|
WO2013010955A1
(en)
|
2011-07-15 |
2013-01-24 |
Morphosys Ag |
Antibodies that are cross-reactive for macrophage migration inhibitory factor (mif) and d-dopachrome tautomerase (d-dt)
|
CN103974976A
(zh)
|
2011-10-19 |
2014-08-06 |
莫佛塞斯公司 |
用于治疗炎性病症的il17c拮抗剂
|
CN108341873B
(zh)
|
2011-12-05 |
2022-03-25 |
诺华股份有限公司 |
表皮生长因子受体3(her3)的抗体
|
EA201491107A1
(ru)
|
2011-12-05 |
2014-11-28 |
Новартис Аг |
Антитела к рецептору эпидермального фактора роста 3 (her3), направленные на домен ii her3
|
US9958437B2
(en)
|
2012-02-03 |
2018-05-01 |
The Governors Of The University Of Alberta |
Method of quantifying peptide-derivative libraries using phage display
|
EP2855521A4
(de)
|
2012-05-24 |
2016-03-02 |
Mountgate Group Ltd |
Zusammensetzungen und verfahren in zusammenhang mit der vorbeugung und behandlung von tollwutinfektion
|
DK2885639T3
(da)
|
2012-08-17 |
2019-07-08 |
Morphosys Ag |
Kompleksspecifikke antistoffer og antistoffragmenter og deres anvendelse
|
JOP20200308A1
(ar)
|
2012-09-07 |
2017-06-16 |
Novartis Ag |
جزيئات إرتباط il-18
|
JP2015536339A
(ja)
|
2012-11-09 |
2015-12-21 |
ファイザー・インク |
血小板由来増殖因子b特異的抗体ならびにこれらの組成物および使用
|
US9428577B2
(en)
|
2012-11-09 |
2016-08-30 |
Pfizer Inc. |
Platelet-derived growth factor B specific antibodies and compositions and uses thereof
|
WO2014096333A1
(en)
|
2012-12-20 |
2014-06-26 |
Morphosys Ag |
Anti-staphylococcal antibodies
|
WO2014159239A2
(en)
|
2013-03-14 |
2014-10-02 |
Novartis Ag |
Antibodies against notch 3
|
NZ710929A
(en)
|
2013-03-15 |
2018-02-23 |
Novartis Ag |
Antibody drug conjugates
|
WO2014167088A1
(en)
|
2013-04-12 |
2014-10-16 |
Morphosys Ag |
Antibodies targeting m-csf
|
WO2014170317A1
(en)
|
2013-04-17 |
2014-10-23 |
Morphosys Ag |
Antibodies targeting specifically human cxcr2
|
WO2015134121A2
(en)
|
2014-01-20 |
2015-09-11 |
President And Fellows Of Harvard College |
Negative selection and stringency modulation in continuous evolution systems
|
JP2017511151A
(ja)
|
2014-03-14 |
2017-04-20 |
イムノコア リミテッド |
Tcrライブラリ
|
WO2016020791A1
(en)
|
2014-08-05 |
2016-02-11 |
Novartis Ag |
Ckit antibody drug conjugates
|
US10920208B2
(en)
|
2014-10-22 |
2021-02-16 |
President And Fellows Of Harvard College |
Evolution of proteases
|
TN2017000173A1
(en)
|
2014-11-14 |
2018-10-19 |
Novartis Ag |
Antibody drug conjugates
|
ES2904573T3
(es)
|
2015-03-27 |
2022-04-05 |
Univ Southern California |
Terapia con células T dirigida a LHR para el tratamiento de tumores sólidos
|
WO2016168631A1
(en)
|
2015-04-17 |
2016-10-20 |
President And Fellows Of Harvard College |
Vector-based mutagenesis system
|
WO2016176652A2
(en)
|
2015-04-29 |
2016-11-03 |
Fred Hutchinson Cancer Research Center |
Modified stem cells and uses thereof
|
JP6985934B2
(ja)
*
|
2015-04-29 |
2021-12-22 |
フレッド ハッチンソン キャンサー リサーチ センター |
操作された造血幹細胞/前駆細胞及び非tエフェクター細胞、ならびにその使用
|
EP3095465A1
(de)
|
2015-05-19 |
2016-11-23 |
U3 Pharma GmbH |
Kombination von fgfr4-inhibitor und gallensäurekomplexbildner
|
US10711064B2
(en)
|
2015-06-04 |
2020-07-14 |
University Of Southern California |
Lym-1 and Lym-2 targeted CAR cell immunotherapy
|
EA201792561A1
(ru)
|
2015-06-05 |
2018-04-30 |
Новартис Аг |
Антитела, нацеленные на морфогенетический белок кости 9 (bmp9), и способы их применения
|
JOP20200312A1
(ar)
|
2015-06-26 |
2017-06-16 |
Novartis Ag |
الأجسام المضادة للعامل xi وطرق الاستخدام
|
WO2017015545A1
(en)
|
2015-07-22 |
2017-01-26 |
President And Fellows Of Harvard College |
Evolution of site-specific recombinases
|
US11524983B2
(en)
|
2015-07-23 |
2022-12-13 |
President And Fellows Of Harvard College |
Evolution of Bt toxins
|
US10612011B2
(en)
|
2015-07-30 |
2020-04-07 |
President And Fellows Of Harvard College |
Evolution of TALENs
|
EA038332B1
(ru)
|
2015-09-09 |
2021-08-10 |
Новартис Аг |
Молекулы, связывающиеся с тимусным стромальным лимфопоэтином (tslp), и способы применения таких молекул
|
SI3347377T1
(sl)
|
2015-09-09 |
2021-06-30 |
Novartis Ag |
Protitelesa, ki vežejo timusni stromalni limfopoietin (tslp) in postopki uporabe protiteles
|
GB201516272D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
GB201516269D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
GB201516277D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR libraries
|
GB201516270D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
GB201516274D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
GB201516265D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
GB201516275D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
AU2016326721C1
(en)
|
2015-09-23 |
2021-06-03 |
Cytoimmune Therapeutics, Inc. |
FLT3 directed car cells for immunotherapy
|
US11180546B2
(en)
|
2016-02-17 |
2021-11-23 |
Novartis Ag |
TGFbeta 2 antibodies
|
AU2017219837B2
(en)
|
2016-02-19 |
2023-08-17 |
Galapagos Nv |
Antibodies for IL-17C
|
TW201802121A
(zh)
|
2016-05-25 |
2018-01-16 |
諾華公司 |
抗因子XI/XIa抗體之逆轉結合劑及其用途
|
EP3538552B1
(de)
|
2016-11-14 |
2023-09-13 |
MorphoSys AG |
Fab-moleküle mit einer nager-hinge-region und einer nichtnager-ch1-region
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
WO2019010164A1
(en)
|
2017-07-06 |
2019-01-10 |
President And Fellows Of Harvard College |
EVOLUTION OF ARNT SYNTHÉTASES
|
EP3444275A1
(de)
|
2017-08-16 |
2019-02-20 |
Exiris S.r.l. |
Monoklonaler antikörper anti-fgfr4
|
WO2019056002A1
(en)
|
2017-09-18 |
2019-03-21 |
President And Fellows Of Harvard College |
CONTINUOUS EVOLUTION FOR STABILIZED PROTEINS
|
WO2019094595A2
(en)
|
2017-11-09 |
2019-05-16 |
Pinteon Therapeutics Inc. |
Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies
|
AU2018372135A1
(en)
|
2017-11-22 |
2020-05-28 |
Novartis Ag |
Reversal binding agents for anti-factor XI/XIa antibodies and uses thereof
|
EP3774926A1
(de)
|
2018-04-05 |
2021-02-17 |
Bio-Rad ABD Serotec GmbH |
Anzeigesysteme für proteine von interesse
|
EP3793596A1
(de)
|
2018-05-16 |
2021-03-24 |
MorphoSys AG |
Antikörper gegen glycoprotein vi
|
WO2019241649A1
(en)
|
2018-06-14 |
2019-12-19 |
President And Fellows Of Harvard College |
Evolution of cytidine deaminases
|
US20210277118A1
(en)
|
2018-06-21 |
2021-09-09 |
Daiichi Sankyo Company, Limited |
Compositions including cd3 antigen binding fragments and uses thereof
|
UY38407A
(es)
|
2018-10-15 |
2020-05-29 |
Novartis Ag |
Anticuerpos estabilizadores de trem2
|
WO2020182974A1
(en)
|
2019-03-14 |
2020-09-17 |
Morphosys Ag |
Antibodies targeting c5ar
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與entpd2抗體之組合療法
|
MX2023000547A
(es)
|
2020-07-16 |
2023-02-13 |
Novartis Ag |
Anticuerpos anti-betacelulina, fragmentos de los mismos, y moleculas de union multiespecificas.
|
EP4217391A1
(de)
|
2020-09-24 |
2023-08-02 |
MorphoSys AG |
Neue humane antikörper, die an humanes cd3-epsilon binden
|
US20240115720A1
(en)
|
2021-01-13 |
2024-04-11 |
Memorial Sloan Kettering Cancer Center |
Antibody-pyrrolobenzodiazepine derivative conjugate
|
JP2024503658A
(ja)
|
2021-01-13 |
2024-01-26 |
メモリアル スローン-ケタリング キャンサー センター |
抗dll3抗体-薬物コンジュゲート
|
TW202323289A
(zh)
|
2021-08-31 |
2023-06-16 |
日商大正製藥股份有限公司 |
抗生長激素抗體
|
WO2023180346A1
(en)
|
2022-03-22 |
2023-09-28 |
Morphosys Ag |
Deimmunized antibodies specific for cd3
|
GB202204159D0
(en)
|
2022-03-24 |
2022-05-11 |
Heptares Therapeutics Ltd |
Antibodies
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