PT2332940E - Azaindoles úteis como inibidores de jak e outras proteínas quinases - Google Patents

Azaindoles úteis como inibidores de jak e outras proteínas quinases

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Publication number
PT2332940E
PT2332940E PT101823656T PT10182365T PT2332940E PT 2332940 E PT2332940 E PT 2332940E PT 101823656 T PT101823656 T PT 101823656T PT 10182365 T PT10182365 T PT 10182365T PT 2332940 E PT2332940 E PT 2332940E
Authority
PT
Portugal
Prior art keywords
inhibitors
protein kinases
jak
azaindoles useful
azaindoles
Prior art date
Application number
PT101823656T
Other languages
English (en)
Portuguese (pt)
Inventor
Michael Mortimore
John Court
Jian Wang
Francesco Salituro
Tiansheng Wang
Jean-Damien Charrier
Luc Farmer
Randy Bethiel
Edmund Harrington
Jeremy Green
Jon Come
David Lauffer
Hayley Binch
Simon Everitt
Damien Fraysse
Daniel Robinson
Joanne Pinder
Albert Pierce
Alex Aronov
Francoise Pierard
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34971569&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2332940(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of PT2332940E publication Critical patent/PT2332940E/pt

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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