PT1187601E - Nova forma de preparacao e a administracao compreendendo um inibidor da bomba de protoes instavel em meio acido - Google Patents

Nova forma de preparacao e a administracao compreendendo um inibidor da bomba de protoes instavel em meio acido

Info

Publication number
PT1187601E
PT1187601E PT00935151T PT00935151T PT1187601E PT 1187601 E PT1187601 E PT 1187601E PT 00935151 T PT00935151 T PT 00935151T PT 00935151 T PT00935151 T PT 00935151T PT 1187601 E PT1187601 E PT 1187601E
Authority
PT
Portugal
Prior art keywords
instable
inhibitor
administration
understanding
pump
Prior art date
Application number
PT00935151T
Other languages
English (en)
Inventor
Rudolf Linder
Rango Dietrich
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of PT1187601E publication Critical patent/PT1187601E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT00935151T 1999-06-07 2000-05-31 Nova forma de preparacao e a administracao compreendendo um inibidor da bomba de protoes instavel em meio acido PT1187601E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99110865 1999-06-07

Publications (1)

Publication Number Publication Date
PT1187601E true PT1187601E (pt) 2005-11-30

Family

ID=8238296

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00935151T PT1187601E (pt) 1999-06-07 2000-05-31 Nova forma de preparacao e a administracao compreendendo um inibidor da bomba de protoes instavel em meio acido

Country Status (31)

Country Link
US (3) US7794752B1 (pt)
EP (2) EP1187601B1 (pt)
JP (1) JP4980527B2 (pt)
KR (1) KR100833633B1 (pt)
CN (1) CN1361683A (pt)
AT (1) ATE300285T1 (pt)
AU (1) AU775995B2 (pt)
BG (1) BG106165A (pt)
BR (1) BR0011347A (pt)
CA (1) CA2376202C (pt)
CZ (1) CZ20014405A3 (pt)
DE (1) DE60021570T2 (pt)
DK (1) DK1187601T3 (pt)
EA (2) EA006899B1 (pt)
EE (1) EE200100660A (pt)
ES (1) ES2246238T3 (pt)
HK (1) HK1046643A1 (pt)
HR (1) HRP20020006A2 (pt)
HU (1) HUP0201637A3 (pt)
IL (2) IL146504A0 (pt)
MX (1) MXPA01012659A (pt)
NO (1) NO20015980L (pt)
PL (1) PL352882A1 (pt)
PT (1) PT1187601E (pt)
SI (1) SI1187601T1 (pt)
SK (1) SK285247B6 (pt)
TR (1) TR200103527T2 (pt)
UA (1) UA74339C2 (pt)
WO (1) WO2000074654A1 (pt)
YU (1) YU86001A (pt)
ZA (1) ZA200110000B (pt)

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EP1616562A1 (en) 2006-01-18
AU5074100A (en) 2000-12-28
EP1187601B1 (en) 2005-07-27
ZA200110000B (en) 2002-12-24
PL352882A1 (en) 2003-09-22
SK285247B6 (sk) 2006-09-07
ES2246238T3 (es) 2006-02-16
YU86001A (sh) 2004-07-15
DK1187601T3 (da) 2005-11-21
NO20015980D0 (no) 2001-12-06
US20080069882A1 (en) 2008-03-20
DE60021570T2 (de) 2006-05-24
HK1046643A1 (zh) 2003-01-24
EA200401241A1 (ru) 2005-02-24
HUP0201637A2 (hu) 2002-11-28
HRP20020006A2 (en) 2003-04-30
ATE300285T1 (de) 2005-08-15
EA006899B1 (ru) 2006-04-28
EA005803B1 (ru) 2005-06-30
TR200103527T2 (tr) 2002-04-22
CA2376202A1 (en) 2000-12-14
UA74339C2 (uk) 2005-12-15
BR0011347A (pt) 2002-03-19
CZ20014405A3 (cs) 2002-04-17
SK18022001A3 (sk) 2002-04-04
KR100833633B1 (ko) 2008-05-30
JP2003501377A (ja) 2003-01-14
US7785630B2 (en) 2010-08-31
DE60021570D1 (de) 2005-09-01
EP1187601A1 (en) 2002-03-20
US7794752B1 (en) 2010-09-14
AU775995B2 (en) 2004-08-19
NO20015980L (no) 2002-01-23
JP4980527B2 (ja) 2012-07-18
WO2000074654A1 (en) 2000-12-14
EE200100660A (et) 2003-04-15
EA200101266A1 (ru) 2002-06-27
US20060127477A1 (en) 2006-06-15
MXPA01012659A (es) 2003-09-04
SI1187601T1 (sl) 2005-12-31
BG106165A (bg) 2002-09-30
US7790198B2 (en) 2010-09-07
IL146504A (en) 2007-02-11
CN1361683A (zh) 2002-07-31
IL146504A0 (en) 2002-07-25
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HUP0201637A3 (en) 2004-05-28
CA2376202C (en) 2008-11-18

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