UA74339C2 - Форма для введення, що включає інгібітор протонної помпи у вигляді окремих одиниць, та спосіб їх одержання - Google Patents
Форма для введення, що включає інгібітор протонної помпи у вигляді окремих одиниць, та спосіб їх одержанняInfo
- Publication number
- UA74339C2 UA74339C2 UA2002010191A UA200210191A UA74339C2 UA 74339 C2 UA74339 C2 UA 74339C2 UA 2002010191 A UA2002010191 A UA 2002010191A UA 200210191 A UA200210191 A UA 200210191A UA 74339 C2 UA74339 C2 UA 74339C2
- Authority
- UA
- Ukraine
- Prior art keywords
- manufacture
- dosage form
- proton pump
- pump inhibitor
- active compound
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/009—Sachets, pouches characterised by the material or function of the envelope
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Винахід належить до галузі фармацевтичної технології й у ньому описана форма для введення нестійких у кислому середовищі діючих речовин, вибраних з групи, що включає нестійкий у кислому середовищі інгібітор протонної помпи, сіль нестійкого у кислому середовищі інгібітору протонної помпи з основою та гідрат солі нестійкого у кислому середовищі інгібітору протонної помпи з основою. Форма для введення включає велику кількість окремих одиниць діючої речовини, що мають форму мікросфер, які можуть бути одержані грануляцією розбризкуванням, та фармацевтичні ексципієнти, при цьому нестійка у кислому середовищі речовина присутня у вигляді окремих одиниць діючої речовини в матриці, що включає суміш щонайменше одного спирту жирного ряду і щонайменше одного твердого парафіну, у матриці, що включає суміш щонайменше одного тригліцериду і щонайменше одного твердого парафіну, або в матриці, що включає суміш щонайменше одного ефіру кислоти жирного ряду і щонайменше одного твердого парафіну.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99110865 | 1999-06-07 | ||
PCT/EP2000/004958 WO2000074654A1 (en) | 1999-06-07 | 2000-05-31 | Novel preparation and administration form comprising an acid-labile active compound |
Publications (1)
Publication Number | Publication Date |
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UA74339C2 true UA74339C2 (uk) | 2005-12-15 |
Family
ID=8238296
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA2002010191A UA74339C2 (uk) | 1999-06-07 | 2000-05-31 | Форма для введення, що включає інгібітор протонної помпи у вигляді окремих одиниць, та спосіб їх одержання |
Country Status (31)
Country | Link |
---|---|
US (3) | US7794752B1 (uk) |
EP (2) | EP1616562A1 (uk) |
JP (1) | JP4980527B2 (uk) |
KR (1) | KR100833633B1 (uk) |
CN (1) | CN1361683A (uk) |
AT (1) | ATE300285T1 (uk) |
AU (1) | AU775995B2 (uk) |
BG (1) | BG106165A (uk) |
BR (1) | BR0011347A (uk) |
CA (1) | CA2376202C (uk) |
CZ (1) | CZ20014405A3 (uk) |
DE (1) | DE60021570T2 (uk) |
DK (1) | DK1187601T3 (uk) |
EA (2) | EA006899B1 (uk) |
EE (1) | EE200100660A (uk) |
ES (1) | ES2246238T3 (uk) |
HK (1) | HK1046643A1 (uk) |
HR (1) | HRP20020006A2 (uk) |
HU (1) | HUP0201637A3 (uk) |
IL (2) | IL146504A0 (uk) |
MX (1) | MXPA01012659A (uk) |
NO (1) | NO20015980L (uk) |
PL (1) | PL352882A1 (uk) |
PT (1) | PT1187601E (uk) |
SI (1) | SI1187601T1 (uk) |
SK (1) | SK285247B6 (uk) |
TR (1) | TR200103527T2 (uk) |
UA (1) | UA74339C2 (uk) |
WO (1) | WO2000074654A1 (uk) |
YU (1) | YU86001A (uk) |
ZA (1) | ZA200110000B (uk) |
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US7357943B2 (en) | 2000-12-07 | 2008-04-15 | Nycomed Gmbh | Pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient |
ATE541564T1 (de) | 2000-12-07 | 2012-02-15 | Nycomed Gmbh | Schnell zerfallende tablette mit einem säurelabilen wirkstoff |
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PE20050150A1 (es) | 2003-05-08 | 2005-03-22 | Altana Pharma Ag | Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo |
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KR101107609B1 (ko) * | 2009-09-21 | 2012-01-25 | 주식회사 한양비이에스티교육 | 태양에너지 발전 및 응용 교육을 위한 보트형 학습교재 |
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2000
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- 2000-05-31 DE DE60021570T patent/DE60021570T2/de not_active Expired - Lifetime
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- 2000-05-31 EP EP05104345A patent/EP1616562A1/en not_active Withdrawn
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