ES2057338T3 - Derivados de cicloheptenopiridina, procedimiento para su preparacion y agentes antiulcerosos que los contienen. - Google Patents
Derivados de cicloheptenopiridina, procedimiento para su preparacion y agentes antiulcerosos que los contienen.Info
- Publication number
- ES2057338T3 ES2057338T3 ES90122644T ES90122644T ES2057338T3 ES 2057338 T3 ES2057338 T3 ES 2057338T3 ES 90122644 T ES90122644 T ES 90122644T ES 90122644 T ES90122644 T ES 90122644T ES 2057338 T3 ES2057338 T3 ES 2057338T3
- Authority
- ES
- Spain
- Prior art keywords
- group
- atom
- hydrogen atom
- halogen atom
- optionally containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003699 antiulcer agent Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000005843 halogen group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 150000007578 6-membered cyclic compounds Chemical class 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000005042 acyloxymethyl group Chemical group 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000005079 alkoxycarbonylmethyl group Chemical group 0.000 abstract 1
- 125000004849 alkoxymethyl group Chemical group 0.000 abstract 1
- 125000005115 alkyl carbamoyl group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003368 amide group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 230000004962 physiological condition Effects 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SE PROPORCIONAN DERIVADOS DE CICLOHEPTEROPIRIDINA REPRESENTADOS POR LA FORMULA GENERAL. [ EN DONDE R REPRESENTA A UN ATOMO DE HIDROGENO O UN ALQUILO INFERIOR; R'' REPRESENTA UN ATOMO DE HIDROGENO, ATOMO HALOGENO, GRUPO ALCOXI INFERIOR, GRUPO CICLOALCOXI INFERIOR, GRUPO AMIDO, GRUPO PHEROXI SUSTITUIDO , GRUPO BENCILOXI SUSTITUIDO, GRUPO ALCOXI INFERIOR QUE DE MANERA OPCIONAL CONTIENE ATOMO (S) HALOGENO (S), GRUPO NITRO, GRUPO HIDROXIL, GRUPO ALQUENILOXY INFERIOR, GRUPO ALQUILIO INFERIOR, O GRUPO NR ELEVADO 4 R ELEVADO 4 (EN DONDE R ELEVADO 4 Y R ELEVADO 5 PUEDEN SE IGUALES O DIFERENTES Y CADA UNA REPRESENTA UN ATOMO DE HIDROGENO O GRUPO ALQUILO INFERIOR, O R ELEVADO 4 Y R ELEVADO 5 SE COMBINAN ENTRE SI CON EL ATOMO DE HIDROGENO ADYACENTE A EL PARA FORMAR UN CICLO DE 5 DRADO) REPRESENTA UN ATOMO DE HIDROGENO, ATOMO HALOGENO, GRUPO ALQUILO INFERIOR QUE OPCIONALMENTE PUEDE CONTENER UN ATOMO HALOGENO, GRUPO ALCOXI INFERIOR QUE DE MANERA OPCIONAL CONTIENE UN ATOMO HALOGENO, GRUPO HIDROXIL, GRUPO ACILO, GRUPO ALCOXICARBONICO, GRUPO NITRO O GRUPO AMINO;R ELEVADO 3 REPRESENTA UN GRUPO ALQUILO INFERIOR, GRUPO ALCOXIMETILO INFERIOR, GRUPO ALQUILOCARBONILO INFERIOR, GRUPO ALCOXICARBONILO INFERIOR, GRUPO CARBANILO, GRUPO ALCILOCARBONILO INFERIOR, GRUPO ALQUILOCARBONILMETILO INFERIOR, GRUPO ALCOXICARBONILMETILO INFERIO, GRUPO ACILOXIMETILO INFERIOR, GRUPO ALQUILSUFONITO INFERIOR, O UN GRUPO PROTECTOR FISIOLOGICAMENTE ACEPTABLE QUE SE PUEDE ELIMINAR EN UN ACIDO MEDIO O BAJO UNA CONDICION FISIOLOGICA ; N REPRESENTA 0 O 1; Y A REPRESENTA UN CARBON METINO O ATOMO DE HIDROGENO] O SUS SALES. ESTOS DERIVADOS Y SUS SALES SON UTILES COMO AGENTES ANTIULCERA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP30763089 | 1989-11-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2057338T3 true ES2057338T3 (es) | 1994-10-16 |
Family
ID=17971348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90122644T Expired - Lifetime ES2057338T3 (es) | 1989-11-29 | 1990-11-27 | Derivados de cicloheptenopiridina, procedimiento para su preparacion y agentes antiulcerosos que los contienen. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5149702A (es) |
| EP (1) | EP0434999B1 (es) |
| AT (1) | ATE110069T1 (es) |
| DE (1) | DE69011645T2 (es) |
| ES (1) | ES2057338T3 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP960232A2 (en) * | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
| EP0983263A1 (en) * | 1997-05-30 | 2000-03-08 | Dr. Reddy's Research Foundation | Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them |
| ATE281178T1 (de) | 1997-07-25 | 2004-11-15 | Altana Pharma Ag | Protonenpumpenhemmer als kombinationstherapeutika mit antibakterielle wirkenden substanzen |
| PT1105105E (pt) | 1998-08-12 | 2006-07-31 | Altana Pharma Ag | Forma de administracao oral para piridin-2-ilmetilsulfinil-1h-benzimidazois |
| US6852739B1 (en) * | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
| SI1187601T1 (sl) | 1999-06-07 | 2005-12-31 | Altana Pharma Ag | Novi pripravek in dajalna oblika, ki obsega kislinsko labilen inhibitor protonske crpalke |
| AU2003254282A1 (en) * | 2002-08-01 | 2004-02-23 | Nitromed, Inc. | Nitrosated proton pump inhibitors, compositions and methods of use |
| EP2112920B1 (en) * | 2003-06-26 | 2018-07-25 | Intellipharmaceutics Corp. | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
| TWI372066B (en) | 2003-10-01 | 2012-09-11 | Wyeth Corp | Pantoprazole multiparticulate formulations |
| US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
| US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
| US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
| CA2648280C (en) | 2006-04-03 | 2014-03-11 | Isa Odidi | Controlled release delivery device comprising an organosol coat |
| US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
| US20100093747A1 (en) * | 2008-10-10 | 2010-04-15 | Erica Brook Goodhew | Method of inducing negative chemotaxis |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE416649B (sv) * | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
| GB8307865D0 (en) * | 1983-03-22 | 1983-04-27 | Fujisawa Pharmaceutical Co | Benzimidazole derivatives |
| GB8417194D0 (en) * | 1984-07-05 | 1984-08-08 | Boots Co Plc | Therapeutic agents |
| DK585485A (da) * | 1984-12-18 | 1986-08-08 | Utsuka Pharm Co Ltd | Tetrahydroquinolinderivat, imidazopyridinderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat med mindst en saadan forbindelse |
| GB8526154D0 (en) * | 1985-02-06 | 1985-11-27 | Kotobuki Seiyaku Co Ltd | 2-substituted cyclo-heptoimidazoles |
| GB8505492D0 (en) * | 1985-03-04 | 1985-04-03 | Roussel Lab Ltd | Chemical compounds |
| US4824856A (en) * | 1985-08-14 | 1989-04-25 | Nippon Chemiphar Co., Ltd. | Method of protecting gastrointestinal tract |
-
1990
- 1990-11-27 AT AT90122644T patent/ATE110069T1/de not_active IP Right Cessation
- 1990-11-27 EP EP90122644A patent/EP0434999B1/en not_active Expired - Lifetime
- 1990-11-27 ES ES90122644T patent/ES2057338T3/es not_active Expired - Lifetime
- 1990-11-27 DE DE69011645T patent/DE69011645T2/de not_active Expired - Fee Related
- 1990-11-27 US US07/618,943 patent/US5149702A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5149702A (en) | 1992-09-22 |
| DE69011645D1 (de) | 1994-09-22 |
| EP0434999A1 (en) | 1991-07-03 |
| ATE110069T1 (de) | 1994-09-15 |
| EP0434999B1 (en) | 1994-08-17 |
| DE69011645T2 (de) | 1995-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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