ES2046528T3 - Derivados heterotetraciclicos de lactamas, proceso para su preparacion y composiciones farmaceuticas a base de los mismos. - Google Patents

Derivados heterotetraciclicos de lactamas, proceso para su preparacion y composiciones farmaceuticas a base de los mismos.

Info

Publication number
ES2046528T3
ES2046528T3 ES198989810282T ES89810282T ES2046528T3 ES 2046528 T3 ES2046528 T3 ES 2046528T3 ES 198989810282 T ES198989810282 T ES 198989810282T ES 89810282 T ES89810282 T ES 89810282T ES 2046528 T3 ES2046528 T3 ES 2046528T3
Authority
ES
Spain
Prior art keywords
heterotetraciclic
lactams
preparation
derivatives
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198989810282T
Other languages
English (en)
Inventor
Jan W. F. Wasley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2046528T3 publication Critical patent/ES2046528T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

SE DESCRIBEN COMPUESTOS DE LA FORMULA I: DONDE R1 - R3, M, N, HET REPRESENTAN LO DEFINIDO EN LA DESCRIPCION; Y SALES ACEPTABLES FARMACEUTICAMENTE DE LOS COMPUESTOS DE LA FORMULA I, DONDE HET REPRESENTA OPCIONALMENTE UN IMIDADOL SUSTITUIDO; LOS METODOS DE PREPARACION; COMPUESTOS FARMACEUTICOS Y SU USO PARA TRATAR DESORDENES COGNITIVOS EN MAMIFEROS. SE PUEDEN PREPARAR POR EJEMPLO POR CONDENSACION DEL COMPUESTO DE LA FORMULA II CON UN COMPUESTO DE LA FORMULA III.
ES198989810282T 1988-04-20 1989-04-11 Derivados heterotetraciclicos de lactamas, proceso para su preparacion y composiciones farmaceuticas a base de los mismos. Expired - Lifetime ES2046528T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/183,802 US4897399A (en) 1988-04-20 1988-04-20 Heterotertracyclic lactam derivatives, pharmaceutical compositions, and method of treating impaired memory and learning

Publications (1)

Publication Number Publication Date
ES2046528T3 true ES2046528T3 (es) 1994-02-01

Family

ID=22674346

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198989810282T Expired - Lifetime ES2046528T3 (es) 1988-04-20 1989-04-11 Derivados heterotetraciclicos de lactamas, proceso para su preparacion y composiciones farmaceuticas a base de los mismos.

Country Status (22)

Country Link
US (1) US4897399A (es)
EP (1) EP0338989B1 (es)
JP (1) JPH0662620B2 (es)
KR (1) KR900016204A (es)
AT (1) ATE86993T1 (es)
AU (1) AU624129B2 (es)
DD (1) DD283823A5 (es)
DE (1) DE68905363T2 (es)
DK (1) DK189389A (es)
ES (1) ES2046528T3 (es)
FI (1) FI91410C (es)
GR (1) GR3007850T3 (es)
HU (1) HU203889B (es)
IE (1) IE891261L (es)
IL (1) IL89942A (es)
MX (1) MX15697A (es)
NO (1) NO168707C (es)
NZ (1) NZ228779A (es)
PH (1) PH26084A (es)
PT (1) PT90302B (es)
YU (1) YU80689A (es)
ZA (1) ZA892861B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015645A (en) * 1989-10-19 1991-05-14 Ciba-Geigy Corporation Tetracyclic pyrrole lactam derivatives
US5204342A (en) * 1989-12-08 1993-04-20 Ciba-Geigy Corporation Saturated tetracyclic nitrogen heterocycles
EP0432099A3 (en) * 1989-12-08 1992-01-08 Ciba-Geigy Ag Hydrogenated nitrogen containing heterocycles
DE4135551A1 (de) * 1991-08-31 1993-03-04 Schering Ag Verwendung von antagonisten oder partiellen agonisten am 5-ht1a-rezeptor zur behandlung und praevention von kognitiven stoerungen
JP2607032B2 (ja) * 1993-07-16 1997-05-07 大日本印刷株式会社 成形同時絵付転写フィルム及びその製造方法
EP2402157A1 (en) 1998-07-14 2012-01-04 Dai Nippon Printing Co., Ltd. Decorative material
EP2316643A1 (en) 2009-10-27 2011-05-04 Dai Nippon Printing Co., Ltd. Decorative sheet and decorative material laminated with the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0252643A1 (en) * 1986-07-01 1988-01-13 BEECHAM - WUELFING GmbH & Co. KG Pyrido[1,2-a]indole derivatives, process for their preparation and pharmaceutical compounds containing them
US4956278A (en) * 1988-02-23 1990-09-11 Louisiana State University Anaplasma marginale antigen, antigen compositions, vaccine and process for the production of said antigen, antigen compositions and vaccine
JPH10786A (ja) * 1996-06-14 1998-01-06 Brother Ind Ltd インクジェット記録装置
JP3394157B2 (ja) * 1997-06-13 2003-04-07 神鋼パンテツク株式会社 有機性廃液の処理方法及びその処理装置

Also Published As

Publication number Publication date
EP0338989B1 (en) 1993-03-17
MX15697A (es) 1993-12-01
DK189389D0 (da) 1989-04-19
FI91410C (fi) 1994-06-27
EP0338989A1 (en) 1989-10-25
DD283823A5 (de) 1990-10-24
JPH0662620B2 (ja) 1994-08-17
US4897399A (en) 1990-01-30
NO168707B (no) 1991-12-16
ATE86993T1 (de) 1993-04-15
IL89942A (en) 1993-07-08
PH26084A (en) 1992-02-06
DK189389A (da) 1989-10-21
IL89942A0 (en) 1989-12-15
GR3007850T3 (es) 1993-08-31
ZA892861B (en) 1989-12-27
FI91410B (fi) 1994-03-15
PT90302B (pt) 1994-09-30
FI891807A0 (fi) 1989-04-17
YU80689A (en) 1991-02-28
DE68905363D1 (de) 1993-04-22
DE68905363T2 (de) 1993-08-05
HU203889B (en) 1991-10-28
IE891261L (en) 1989-10-20
AU624129B2 (en) 1992-06-04
HUT50176A (en) 1989-12-28
NO891608D0 (no) 1989-04-19
AU3255989A (en) 1989-10-26
NO168707C (no) 1992-03-25
JPH0242080A (ja) 1990-02-13
FI891807A (fi) 1989-10-21
PT90302A (pt) 1989-11-10
KR900016204A (ko) 1990-11-12
NO891608L (no) 1989-10-23
NZ228779A (en) 1991-06-25

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