|
GB9818732D0
(en)
*
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
|
GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
|
ES2244210T3
(es)
|
1998-08-27 |
2005-12-01 |
Spirogen Limited |
Pirrolobenzodiazepinas.
|
|
GB9818731D0
(en)
*
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Compounds
|
|
GB0226593D0
(en)
*
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
|
DE60326060D1
(de)
*
|
2003-03-31 |
2009-03-19 |
Council Scient Ind Res |
Nichtvernetzende pyrroloä2,1-cüä1,4übenzodiazepine als potentielle antitumor-agentien und ihre herstellung
|
|
GB0321295D0
(en)
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
|
GB0416511D0
(en)
*
|
2003-10-22 |
2004-08-25 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
AU2004284075A1
(en)
|
2003-10-22 |
2005-05-06 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto
|
|
JPWO2005040172A1
(ja)
*
|
2003-10-29 |
2007-03-08 |
協和醗酵工業株式会社 |
三環性プロリン誘導体
|
|
JP4718328B2
(ja)
*
|
2003-12-31 |
2011-07-06 |
カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ |
Ｃ８連結したピロロ［２，１−ｃ］［１，４］ベンゾジアゼピン−アクリドン／アクリジン・ハイブリッド
|
|
JP4520411B2
(ja)
*
|
2003-12-31 |
2010-08-04 |
カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ |
ピロロ［２，１−ｃ］［１，４］ベンゾジアゼピン・ハイブリッドの調製方法
|
|
GB0404574D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Amino acids
|
|
ES2381858T3
(es)
*
|
2004-03-01 |
2012-06-01 |
Spirogen Limited |
Derivados de 11-hidroxi-5H-pirrolo[2,1-C][1,4]benzodiazepin-5-ona como intermedios clave para la preparación de pirrolobenzodiazepinas sustituidas en C2
|
|
GB0404578D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0404577D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
US7528126B2
(en)
|
2004-03-09 |
2009-05-05 |
Spirogen Limited |
Pyrrolobenzodiazepines
|
|
US7056913B2
(en)
|
2004-03-30 |
2006-06-06 |
Council Of Scientific And Industrial Research |
C8—linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids
|
|
US6951853B1
(en)
|
2004-03-30 |
2005-10-04 |
Council Of Scientific And Industrial Research |
Process for preparing pyrrolo[2, 1-c] [1,4] benzodiazepine hybrids
|
|
FR2869231B1
(fr)
*
|
2004-04-27 |
2008-03-14 |
Sod Conseils Rech Applic |
Composition therapeutique contenant au moins un derive de la pyrrolobenzodiazepine et la fludarabine
|
|
GB0410725D0
(en)
*
|
2004-05-13 |
2004-06-16 |
Spirogen Ltd |
Pyrrolobenzodiazepine therapeutic agents
|
|
GB0508084D0
(en)
*
|
2005-04-21 |
2005-06-01 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
WO2006111759A1
(en)
*
|
2005-04-21 |
2006-10-26 |
Spirogen Limited |
Pyrrolobenzodiazepines
|
|
DE602006006199D1
(de)
*
|
2005-10-05 |
2009-05-20 |
Spirogen Ltd |
4-ä4-(5-oxo-2,3,5,11a-tetrahydro-5h-pyrrolo ä2, 1-cüä1,4übenzodiazepin-8-yloxy)-butyrylaminoü-1h-pyrrol-2-carbonsäurealkylesterderivate und verwandte verbindung zur behandlung einer proliferativen erkrankung
|
|
PL1813614T3
(pl)
|
2006-01-25 |
2012-03-30 |
Sanofi Sa |
Środki cytotoksyczne zawierające nowe pochodne tomaymycyny
|
|
DE102006013678A1
(de)
*
|
2006-03-24 |
2007-09-27 |
Bayerische Motoren Werke Ag |
Gleit- oder Schmiermittel und Verfahren zum Aufziehen eines Fahrzeugreifens auf eine Felge
|
|
ES2673822T3
(es)
|
2006-07-18 |
2018-06-25 |
Sanofi |
Anticuerpo antagonista contra EphA2 para el tratamiento de cáncer
|
|
GB0619325D0
(en)
|
2006-09-30 |
2006-11-08 |
Univ Strathclyde |
New compounds
|
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
PT2019104E
(pt)
|
2007-07-19 |
2013-12-03 |
Sanofi Sa |
Agentes citotóxicos compreendendo novos derivados de tomaimicina e sua utilização terapêutica
|
|
KR101764927B1
(ko)
|
2008-04-30 |
2017-08-03 |
이뮤노젠 아이엔씨 |
가교제 및 그 용도
|
|
GB0813432D0
(en)
|
2008-07-22 |
2008-08-27 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819095D0
(en)
*
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819097D0
(en)
*
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
AU2015224492B2
(en)
*
|
2009-02-05 |
2017-04-20 |
Immunogen, Inc. |
Novel benzodiazepine derivatives
|
|
CN108727407B
(zh)
|
2009-02-05 |
2022-01-28 |
伊缪诺金公司 |
新型苯并二氮杂䓬衍生物
|
|
WO2010141566A1
(en)
|
2009-06-03 |
2010-12-09 |
Immunogen, Inc. |
Conjugation methods
|
|
FR2949469A1
(fr)
*
|
2009-08-25 |
2011-03-04 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application en therapeutique
|
|
AR078470A1
(es)
|
2009-10-02 |
2011-11-09 |
Sanofi Aventis |
Anticuerpos que se unen especificamente al receptor epha2
|
|
KR101671360B1
(ko)
|
2010-04-15 |
2016-11-01 |
시애틀 지네틱스, 인크. |
표적화된 피롤로벤조디아제핀 접합체
|
|
TWI540136B
(zh)
|
2010-04-15 |
2016-07-01 |
梅迪繆思有限公司 |
吡咯并苯并二氮呯及其共軛物
|
|
GB201006340D0
(en)
*
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
|
JP5875083B2
(ja)
|
2010-04-15 |
2016-03-02 |
メディミューン リミテッド |
増殖性疾患治療用ピロロベンゾジアゼピン
|
|
FR2963007B1
(fr)
|
2010-07-26 |
2013-04-05 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application therapeutique
|
|
WO2012112708A1
(en)
|
2011-02-15 |
2012-08-23 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives and methods of preparation
|
|
FR2972006B1
(fr)
|
2011-02-24 |
2016-03-25 |
Centre Nat Rech Scient |
Nouveaux fragments d'il-33 superactifs et leurs utilisations
|
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
|
MX341524B
(es)
|
2011-09-20 |
2016-08-24 |
Medimmune Ltd |
Pirrolobenzodiazepinas como compuestos pbd dimericos asimetricos para inclusion en conjugados dirigidos.
|
|
EA026643B1
(ru)
*
|
2011-10-14 |
2017-04-28 |
Сиэтл Дженетикс, Инк. |
Пирролбензодиазепины и конъюгаты направленного действия
|
|
WO2013055990A1
(en)
|
2011-10-14 |
2013-04-18 |
Seattle Genetics, Inc. |
Pyrrolobenzodiazepines and targeted conjugates
|
|
EA027386B1
(ru)
|
2011-10-14 |
2017-07-31 |
Медимьюн Лимитед |
Пирролобензодиазепины
|
|
SG11201401406YA
(en)
|
2011-10-14 |
2014-05-29 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
US9399073B2
(en)
|
2011-10-14 |
2016-07-26 |
Seattle Genetics, Inc. |
Pyrrolobenzodiazepines
|
|
CA2850096C
(en)
|
2011-10-14 |
2018-07-03 |
Spirogen Sarl |
Synthesis method and intermediates useful in the preparation of pyrrolobenzodiazepines
|
|
JP6401060B2
(ja)
|
2012-02-24 |
2018-10-03 |
アッヴィ・ステムセントルクス・エル・エル・シー |
抗ｓｅｚ６抗体及び使用方法
|
|
NZ628804A
(en)
|
2012-02-24 |
2017-08-25 |
Abbvie Stemcentrx Llc |
Dll3 modulators and methods of use
|
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
|
AU2013255612B2
(en)
|
2012-04-30 |
2017-06-22 |
Medimmune Limited |
Pyrrolobenzodiazepines
|
|
US9376440B2
(en)
|
2012-04-30 |
2016-06-28 |
Medimmune Limited |
Pyrrolobenzodiazepines as antiproliferative agents
|
|
SG11201407106XA
(en)
|
2012-05-01 |
2014-11-27 |
Genentech Inc |
Anti-pmel17 antibodies and immunoconjugates
|
|
JP2015523380A
(ja)
|
2012-07-09 |
2015-08-13 |
ジェネンテック， インコーポレイテッド |
抗ｃｄ７９ｂ抗体を含む免疫複合体
|
|
TW201406785A
(zh)
|
2012-07-09 |
2014-02-16 |
Genentech Inc |
抗ｃｄ２２抗體及免疫結合物
|
|
CN104717979A
(zh)
|
2012-08-02 |
2015-06-17 |
基因泰克公司 |
抗etbr抗体和免疫偶联物
|
|
EP2887965A1
(en)
|
2012-08-22 |
2015-07-01 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
AU2013328580B2
(en)
|
2012-10-12 |
2016-01-21 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
ES2713164T3
(es)
|
2012-10-12 |
2019-05-20 |
Medimmune Ltd |
Pirrolobenzodiazepinas y conjugados de las mismas
|
|
WO2014057114A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-anti-psma antibody conjugates
|
|
US9745303B2
(en)
|
2012-10-12 |
2017-08-29 |
Medimmune Limited |
Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
|
|
RS57104B1
(sr)
|
2012-10-12 |
2018-06-29 |
Adc Therapeutics Sa |
Konjugati pirolobenzodiazepin-antitela
|
|
JP6392765B2
(ja)
|
2012-10-12 |
2018-09-19 |
エイディーシー・セラピューティクス・エス・アーＡｄｃ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｓａ |
ピロロベンゾジアゼピン−抗体結合体
|
|
WO2014057120A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
NZ707534A
(en)
|
2012-10-12 |
2018-08-31 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
|
EP2906253B9
(en)
|
2012-10-12 |
2019-02-27 |
ADC Therapeutics SA |
Pyrrolobenzodiazepine - anti-psma antibody conjugates
|
|
JP6133431B2
(ja)
|
2012-11-24 |
2017-05-24 |
ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ．Ｈａｎｇｚｈｏｕ Ｄａｃ Ｂｉｏｔｅｃｈ Ｃｏ．，Ｌｔｄ． |
親水性連結体及び薬物分子と細胞結合分子との共役反応における親水性連結体の使用
|
|
CA2894961C
(en)
|
2012-12-21 |
2020-09-15 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EA032986B1
(ru)
|
2012-12-21 |
2019-08-30 |
Медимьюн Лимитед |
Пирролобензодиазепины
|
|
ME03394B
(me)
|
2013-02-22 |
2020-01-20 |
Medimmune Ltd |
Antidllз-antitelo-pbd konjugati i nihovа upotreba
|
|
US9649390B2
(en)
|
2013-03-13 |
2017-05-16 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
TWI680766B
(zh)
|
2013-03-13 |
2020-01-01 |
英商梅迪繆思有限公司 |
吡咯并苯并二氮呯及其共軛物
|
|
MX362970B
(es)
|
2013-03-13 |
2019-02-28 |
Medimmune Ltd |
Pirrolobenzodiazepinas y conjugados de las mismas.
|
|
KR20150127199A
(ko)
|
2013-03-14 |
2015-11-16 |
제넨테크, 인크. |
항-b7-h4 항체 및 면역접합체
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
EP3033111B1
(en)
|
2013-08-12 |
2019-03-13 |
Genentech, Inc. |
1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
|
|
US9993566B2
(en)
|
2013-08-28 |
2018-06-12 |
Abbvie Stemcentrx Llc |
SEZ6 modulators and methods of use
|
|
BR112016004242A8
(pt)
|
2013-08-28 |
2018-06-12 |
Stemcentrx Inc |
Métodos para conjugação sítio-específica de anticorpos e composições
|
|
WO2015038984A2
(en)
|
2013-09-12 |
2015-03-19 |
Halozyme, Inc. |
Modified anti-epidermal growth factor receptor antibodies and methods of use thereof
|
|
HK1218124A1
(zh)
|
2013-09-17 |
2017-02-03 |
豪夫迈．罗氏有限公司 |
使用抗lgr5抗体的方法
|
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
US10010624B2
(en)
|
2013-10-11 |
2018-07-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3054986B1
(en)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
EP3054985B1
(en)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
US10053511B2
(en)
|
2013-11-06 |
2018-08-21 |
Abbvie Stemcentrx Llc |
Anti-claudin antibodies and methods of use
|
|
CA3178867A1
(en)
|
2013-11-27 |
2015-06-04 |
Redwood Bioscience, Inc. |
Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
|
|
CN109575136A
(zh)
|
2013-12-12 |
2019-04-05 |
艾伯维施特姆森特克斯有限责任公司 |
新型抗dpep3抗体和使用方法
|
|
TW201533060A
(zh)
|
2013-12-13 |
2015-09-01 |
Genentech Inc |
抗ｃｄ３３抗體及免疫結合物
|
|
BR112016013258A2
(pt)
|
2013-12-16 |
2018-01-16 |
Genentech Inc |
composto conjugado anticorpo-droga, composição farmacêutica, método para tratar câncer e kit
|
|
KR20170008202A
(ko)
|
2014-02-21 |
2017-01-23 |
애브비 스템센트알엑스 엘엘씨 |
흑색종에 사용하기 위한 항-ｄｌｌ3 항체 및 약물 접합체
|
|
PT3122757T
(pt)
|
2014-02-28 |
2023-11-03 |
Hangzhou Dac Biotech Co Ltd |
Ligantes carregados e as suas utilizações em conjugação
|
|
GB201407816D0
(en)
|
2014-05-02 |
2014-06-18 |
King S College London |
Pyrrolobenzodiazepine Compounds
|
|
WO2015179658A2
(en)
|
2014-05-22 |
2015-11-26 |
Genentech, Inc. |
Anti-gpc3 antibodies and immunoconjugates
|
|
ES3034398T3
(en)
|
2014-08-28 |
2025-08-18 |
Bioatla Inc |
Conditionally active chimeric antigen receptors for modified t-cells
|
|
US9381256B2
(en)
|
2014-09-03 |
2016-07-05 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
ES2815353T3
(es)
|
2014-09-03 |
2021-03-29 |
Immunogen Inc |
Derivados de benzodiazepina citotóxicos
|
|
TW201617368A
(zh)
|
2014-09-05 |
2016-05-16 |
史坦森特瑞斯公司 |
新穎抗ｍｆｉ２抗體及使用方法
|
|
CN106687141A
(zh)
|
2014-09-10 |
2017-05-17 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓及其缀合物
|
|
EA201790569A1
(ru)
|
2014-09-12 |
2017-08-31 |
Дженентек, Инк. |
Антитела и иммуноконъюгаты против cll-1
|
|
BR112017003236A2
(pt)
|
2014-09-12 |
2017-11-28 |
Genentech Inc |
anticorpos elaborados com cisteína, conjugados de droga e anticorpos, método de preparação de conjugado de droga e anticorpo e composição farmacêutica
|
|
JP6943760B2
(ja)
|
2014-09-12 |
2021-10-06 |
ジェネンテック， インコーポレイテッド |
抗ｂ７−ｈ４抗体及び免疫複合体
|
|
SG11201701623UA
(en)
|
2014-09-12 |
2017-03-30 |
Genentech Inc |
Anti-her2 antibodies and immunoconjugates
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
KR20170055521A
(ko)
|
2014-09-17 |
2017-05-19 |
제넨테크, 인크. |
항-her2 항체를 포함하는 면역콘주게이트
|
|
BR112017011111A2
(pt)
|
2014-11-25 |
2017-12-26 |
Adc Therapeutics Sa |
conjugados de pirrolobenzodiazepina-anticorpo
|
|
SI3333191T1
(sl)
|
2014-12-11 |
2021-03-31 |
Pierre Fabre Medicament |
Proti C10ORF54 protitelesa in uporaba le-teh
|
|
AU2016206808A1
(en)
|
2015-01-14 |
2017-08-31 |
Bristol-Myers Squibb Company |
Heteroarylene-bridged benzodiazepine dimers, conjugates thereof, and methods of making and using
|
|
CN107428780B
(zh)
|
2015-01-14 |
2020-09-04 |
百时美施贵宝公司 |
苯并二氮杂*二聚体、其缀合物及制备和使用方法
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
GB201510010D0
(en)
|
2015-06-09 |
2015-07-22 |
King S College London |
PDD and BPD compounds
|
|
CN112125929A
(zh)
|
2015-06-15 |
2020-12-25 |
杭州多禧生物科技有限公司 |
用于偶联的亲水链接体
|
|
CN108391434A
(zh)
|
2015-06-23 |
2018-08-10 |
百时美施贵宝公司 |
大环苯并二氮杂*二聚体、其缀合物、制备和用途
|
|
AU2015242213A1
(en)
|
2015-07-12 |
2018-03-08 |
Hangzhou Dac Biotech Co., Ltd |
Bridge linkers for conjugation of cell-binding molecules
|
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
|
SI3325482T1
(sl)
|
2015-07-21 |
2020-11-30 |
Immunogen, Inc. |
Postopki za pripravo citotoksičnih benzodiazepinskih derivatov
|
|
GB201514928D0
(en)
|
2015-08-21 |
2015-10-07 |
King S College London |
PDD compounds
|
|
US20180339985A1
(en)
|
2015-08-21 |
2018-11-29 |
Femtogenix Limited |
Pdd compounds
|
|
EP3350224B1
(en)
|
2015-09-20 |
2024-06-19 |
The United States of America, as Represented By the Secretary, Department of Health and Human Services |
Monoclonal antibodies specific for fibroblast growth factor receptor 4 (fgfr4) and methods of their use
|
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
|
ES2908470T3
(es)
|
2015-11-09 |
2022-04-29 |
Scherer Technologies Llc R P |
Conjugados de anticuerpo anti-CD22-maitansina y métodos de uso de los mismos
|
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
|
MA45328A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Compositions acide nucléique-polypeptide et utilisations de celles-ci
|
|
WO2017180842A1
(en)
|
2016-04-15 |
2017-10-19 |
Bioatla, Llc |
Anti-axl antibodies, antibody fragments and their immunoconjugates and uses thereof
|
|
CA3021098A1
(en)
|
2016-04-21 |
2017-10-26 |
Abbvie Stemcentrx Llc |
Novel anti-bmpr1b antibodies and methods of use
|
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
WO2017196847A1
(en)
|
2016-05-10 |
2017-11-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Variable new antigen receptor (vnar) antibodies and antibody conjugates targeting tumor and viral antigens
|
|
TW201808336A
(zh)
|
2016-05-11 |
2018-03-16 |
賽諾菲公司 |
用抗ｍｕｃ１類美登素免疫綴合物抗體治療腫瘤的治療方案
|
|
CN109311987A
(zh)
|
2016-05-13 |
2019-02-05 |
生物蛋白有限公司 |
抗ror2抗体、抗体片段和它们的免疫缀合物以及其用途
|
|
EP3465221B1
(en)
|
2016-05-27 |
2020-07-22 |
H. Hoffnabb-La Roche Ag |
Bioanalytical method for the characterization of site-specific antibody-drug conjugates
|
|
WO2017214182A1
(en)
|
2016-06-07 |
2017-12-14 |
The United States Of America. As Represented By The Secretary, Department Of Health & Human Services |
Fully human antibody targeting pdi for cancer immunotherapy
|
|
CA3031559A1
(en)
|
2016-08-02 |
2018-02-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies targeting glypican-2 (gpc2) and use thereof
|
|
EP3494139B1
(en)
|
2016-08-05 |
2022-01-12 |
F. Hoffmann-La Roche AG |
Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
|
|
CN109689111B
(zh)
|
2016-08-11 |
2024-04-05 |
基因泰克公司 |
吡咯并苯并二氮杂䓬前药及其抗体缀合物
|
|
WO2018069289A1
(en)
|
2016-10-11 |
2018-04-19 |
Medimmune Limited |
Antibody-drug conjugates with immune-mediated therapy agents
|
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
KR20220147720A
(ko)
|
2016-11-14 |
2022-11-03 |
항저우 디에이씨 바이오테크 씨오, 엘티디 |
결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
|
|
KR102532256B1
(ko)
|
2016-11-21 |
2023-05-12 |
쿠레아브 게엠베하 |
항-gp73 항체 및 면역접합체
|
|
FR3059550B1
(fr)
|
2016-12-01 |
2020-01-03 |
Universite De Rouen Normandie |
Traitement des troubles causes par l'alcoolisation foetale (tcaf)
|
|
US11236171B2
(en)
|
2016-12-21 |
2022-02-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies specific for FLT3 and uses thereof
|
|
BR112019016373B1
(pt)
|
2017-02-08 |
2022-01-25 |
Medimmune Limited |
Conjugado anticorpo-fármaco que se liga ao axl, composição e composição farmacêutica que compreende o mesmo e uso terapêutico do dito conjugado
|
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
|
US11370801B2
(en)
*
|
2017-04-18 |
2022-06-28 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
TW201839001A
(zh)
|
2017-04-20 |
2018-11-01 |
美商伊繆諾金公司 |
細胞毒性苯并二氮平衍生物及其綴合物
|
|
EP3612234B1
(en)
|
2017-04-20 |
2024-03-13 |
ADC Therapeutics SA |
Combination therapy with an anti-axl antibody-drug conjugate
|
|
EP3625256A1
(en)
|
2017-05-19 |
2020-03-25 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Human monoclonal antibody targeting tnfr2 for cancer immunotherapy
|
|
JP7145891B2
(ja)
|
2017-06-14 |
2022-10-03 |
アーデーセー セラピューティクス ソシエテ アノニム |
抗ｃｄ１９ ａｄｃを投与するための投与レジメ
|
|
CA3066953A1
(en)
|
2017-06-30 |
2019-01-03 |
Lentigen Technology, Inc. |
Human monoclonal antibodies specific for cd33 and methods of their use
|
|
WO2019005208A1
(en)
|
2017-06-30 |
2019-01-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
ANTIBODIES TO HUMAN MESOTHELIN AND USES IN ANTICANCER THERAPY
|
|
JP7368856B2
(ja)
|
2017-07-25 |
2023-10-25 |
トゥルーバインディング，インコーポレイテッド |
Ｔｉｍ－３とそのリガンドとの相互作用の遮断によるがん治療
|
|
PT3668874T
(pt)
|
2017-08-18 |
2022-02-24 |
Medimmune Ltd |
Conjugados de pirrolobenzodiazepina
|
|
CN117003875A
(zh)
|
2017-09-29 |
2023-11-07 |
第一三共株式会社 |
抗体或其功能性片段、多核苷酸、表达载体、宿主细胞、糖链重构抗体、药物组合物、应用
|
|
WO2019096788A1
(en)
|
2017-11-14 |
2019-05-23 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
KR20200110745A
(ko)
|
2017-12-15 |
2020-09-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
항 - ｃｃｔ5 결합 분자 및 이의 사용 방법
|
|
EP3732178A1
(en)
|
2017-12-28 |
2020-11-04 |
ImmunoGen, Inc. |
Benzodiazepine derivatives
|
|
GB201803342D0
(en)
*
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3801630A1
(en)
|
2018-05-25 |
2021-04-14 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
FR3081707A1
(fr)
|
2018-05-30 |
2019-12-06 |
Universite De Rouen Normandie |
Traitement des troubles neurologiques causes par l'alcoolisation foetale
|
|
JP7459043B2
(ja)
|
2018-07-12 |
2024-04-01 |
ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
親和性成熟ｃｄ２２特異的モノクローナル抗体およびその使用
|
|
CA3106544A1
(en)
|
2018-08-08 |
2020-02-13 |
Mitchell Ho |
High affinity monoclonal antibodies targeting glypican-2 and uses thereof
|
|
AU2019363153A1
(en)
|
2018-10-19 |
2021-05-06 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
KR20210081349A
(ko)
|
2018-10-19 |
2021-07-01 |
메드임뮨 리미티드 |
피롤로벤조디아제핀 컨쥬게이트
|
|
IL319265A
(en)
|
2018-12-21 |
2025-04-01 |
Avidity Biosciences Inc |
Anti-transferrin receptor antibodies and their uses
|
|
US12180296B2
(en)
|
2019-01-08 |
2024-12-31 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Cross species single domain antibodies targeting mesothelin for treating solid tumors
|
|
CN113784987B
(zh)
|
2019-01-22 |
2024-09-13 |
美国政府(由卫生和人类服务部的部长所代表) |
靶向磷脂酰肌醇蛋白聚糖-1的高亲和力单克隆抗体和使用方法
|
|
CN116063505B
(zh)
|
2019-01-30 |
2024-05-03 |
真和制药有限公司 |
抗gal3抗体及其用途
|
|
MX2021010477A
(es)
|
2019-03-15 |
2021-10-01 |
Medimmune Ltd |
Dimeros de azetidobenzodiazepina y conjugados que los comprenden para uso en el tratamiento de cancer.
|
|
US20230094471A1
(en)
|
2019-03-29 |
2023-03-30 |
Immunogen, Inc. |
Cytotoxic bis-benzodiazepine derivatives and conjugates thereof with cell-binding agents for inhibiting abnormal cell growth or for treating proliferative diseases
|
|
CN119899265A
(zh)
|
2019-10-22 |
2025-04-29 |
美国政府(由卫生和人类服务部的部长所代表) |
用于治疗多种实体瘤的靶向b7h3（cd276）的高亲和力纳米抗体
|
|
AU2020402752A1
(en)
|
2019-12-12 |
2022-06-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibody-drug conjugates specific for CD276 and uses thereof
|
|
CA3172111A1
(en)
|
2020-03-19 |
2021-09-23 |
Barbora MALECOVA |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
|
EP4656242A2
(en)
|
2020-03-27 |
2025-12-03 |
Avidity Biosciences, Inc. |
Compositions and methods of treating muscle dystrophy
|
|
US12281166B2
(en)
|
2020-05-26 |
2025-04-22 |
Truebinding, Inc. |
Methods of treating inflammatory diseases by blocking Galectin-3
|
|
WO2022093745A1
(en)
|
2020-10-26 |
2022-05-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies targeting sars coronavirus spike protein and uses thereof
|
|
WO2022232612A1
(en)
|
2021-04-29 |
2022-11-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Lassa virus-specific nanobodies and methods of their use
|
|
AU2022291120A1
(en)
|
2021-06-09 |
2023-11-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Cross species single domain antibodies targeting pd-l1 for treating solid tumors
|
|
EP4370555A4
(en)
|
2021-07-13 |
2025-11-12 |
Truebinding Inc |
METHODS FOR PREVENTING PROTEIN AGGREGATION
|
|
CN118265544A
(zh)
|
2021-09-16 |
2024-06-28 |
艾维迪提生物科学公司 |
治疗面肩肱型肌营养不良的组合物和方法
|
|
EP4426727A2
(en)
|
2021-11-03 |
2024-09-11 |
Hangzhou Dac Biotech Co., Ltd. |
Specific conjugation of an antibody
|
|
CN118524852A
(zh)
|
2021-11-09 |
2024-08-20 |
真和制药有限公司 |
治疗或抑制心血管疾病的方法
|
|
KR20250006932A
(ko)
|
2022-05-03 |
2025-01-13 |
제넨테크, 인크. |
항-Ly6E 항체, 면역접합체 및 이들의 용도
|
|
WO2025019228A1
(en)
|
2023-07-20 |
2025-01-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Fully human monoclonal antibodies and chimeric antigen receptors against cd276 for the treatment of solid tumors
|
|
WO2025171238A1
(en)
|
2024-02-07 |
2025-08-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies that bind the juxta-membrane region of mesothelin and uses thereof
|