NO993691L - Endothelin-antagonister: N-[[2'-[[(4,5-dimetyl-3-oksazolyl)amino]sulfonyl]-4-(2-oksazolyl[[1,1'-bifenyl]-N,3,3-Trimethylbutanamid og N-(4,5-dimethyl-3-isoksalyl)-2'-[3,3-dimetyl-2-okso-1-pyrrolidinyl)metyl]-4'-(2-oksazolyl)[1,1'-bifenyl]-2-sulfo - Google Patents

Endothelin-antagonister: N-[[2'-[[(4,5-dimetyl-3-oksazolyl)amino]sulfonyl]-4-(2-oksazolyl[[1,1'-bifenyl]-N,3,3-Trimethylbutanamid og N-(4,5-dimethyl-3-isoksalyl)-2'-[3,3-dimetyl-2-okso-1-pyrrolidinyl)metyl]-4'-(2-oksazolyl)[1,1'-bifenyl]-2-sulfo

Info

Publication number
NO993691L
NO993691L NO993691A NO993691A NO993691L NO 993691 L NO993691 L NO 993691L NO 993691 A NO993691 A NO 993691A NO 993691 A NO993691 A NO 993691A NO 993691 L NO993691 L NO 993691L
Authority
NO
Norway
Prior art keywords
oxazolyl
dimethyl
biphenyl
isoxalyl
trimethylbutanamide
Prior art date
Application number
NO993691A
Other languages
English (en)
Other versions
NO313142B1 (no
NO993691D0 (no
Inventor
Natesan Murugesan
Joel C Barrish
Zhengxiang Gu
Richard A Morrison
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO993691L publication Critical patent/NO993691L/no
Publication of NO993691D0 publication Critical patent/NO993691D0/no
Publication of NO313142B1 publication Critical patent/NO313142B1/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO19993691A 1997-01-30 1999-07-29 Endothelin-antagonister: N-[[2'-[[(4,5-dimetyl-3- isoksazolyl)amino]sulfonyl]-4-(2-oksazolyl[[1,1'-bifenyl]-2-yl]metyl]-N,3,3-trimetylbutanamid og N-(4,5-dimetyl-3-isoksazolyl)-2'-[(3,3-dimetyl-2-okso-1-pyrrolidinyl)metyl]-4'-(2-oksazolyl)[1,1'-b NO313142B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3583297P 1997-01-30 1997-01-30
PCT/US1998/001490 WO1998033780A1 (en) 1997-01-30 1998-01-26 Endothelin antagonists: n-[[2'-[ [(4,5-dimethyl-3-isoxazolyl) amino]sulfonyl]-4-(2-oxazolyl) [1,1'-biphenyl]-2-yl]methyl] -n,3,3-trimethylbutanamide and n-(4,5-dimethyl-3-isoxazolyl) -2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl) methyl] -4'-(2-oxazolyl)[1,1'-biphenyl]-2-sulfonamide and salts thereof

Publications (3)

Publication Number Publication Date
NO993691L true NO993691L (no) 1999-07-29
NO993691D0 NO993691D0 (no) 1999-07-29
NO313142B1 NO313142B1 (no) 2002-08-19

Family

ID=21885049

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19993691A NO313142B1 (no) 1997-01-30 1999-07-29 Endothelin-antagonister: N-[[2'-[[(4,5-dimetyl-3- isoksazolyl)amino]sulfonyl]-4-(2-oksazolyl[[1,1'-bifenyl]-2-yl]metyl]-N,3,3-trimetylbutanamid og N-(4,5-dimetyl-3-isoksazolyl)-2'-[(3,3-dimetyl-2-okso-1-pyrrolidinyl)metyl]-4'-(2-oksazolyl)[1,1'-b

Country Status (22)

Country Link
US (1) US6043265A (no)
EP (1) EP0996618B1 (no)
JP (1) JP2002513397A (no)
KR (1) KR20000070584A (no)
CN (1) CN1117738C (no)
AR (1) AR015358A1 (no)
AT (1) ATE254115T1 (no)
AU (1) AU730111B2 (no)
BR (1) BR9807098A (no)
CA (1) CA2279178A1 (no)
CZ (1) CZ236299A3 (no)
DE (1) DE69819729T2 (no)
ES (1) ES2205451T3 (no)
HU (1) HUP0001310A3 (no)
IL (1) IL130622A (no)
NO (1) NO313142B1 (no)
NZ (1) NZ336380A (no)
PL (1) PL334773A1 (no)
RU (1) RU2183632C2 (no)
TW (1) TW536540B (no)
WO (1) WO1998033780A1 (no)
ZA (1) ZA98759B (no)

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KR100359396B1 (ko) * 1995-04-04 2003-03-15 텍사스 바이오테크놀로지 코포레이션 엔도텔린의활성을조절하는티에닐-,푸릴-및피롤릴설폰아미드및이의유도체
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HUP0001310A2 (hu) 2001-06-28
JP2002513397A (ja) 2002-05-08
AU6134998A (en) 1998-08-25
BR9807098A (pt) 2000-04-18
PL334773A1 (en) 2000-03-13
ZA98759B (en) 1999-07-29
US6043265A (en) 2000-03-28
DE69819729T2 (de) 2004-09-23
TW536540B (en) 2003-06-11
EP0996618A1 (en) 2000-05-03
NZ336380A (en) 2001-04-27
IL130622A (en) 2003-01-12
ATE254115T1 (de) 2003-11-15
EP0996618A4 (en) 2000-05-03
ES2205451T3 (es) 2004-05-01
CZ236299A3 (cs) 1999-11-17
CN1244862A (zh) 2000-02-16
RU2183632C2 (ru) 2002-06-20
NO313142B1 (no) 2002-08-19
WO1998033780A1 (en) 1998-08-06
HUP0001310A3 (en) 2001-07-30
AU730111B2 (en) 2001-02-22
DE69819729D1 (de) 2003-12-18
NO993691D0 (no) 1999-07-29
AR015358A1 (es) 2001-05-02
CN1117738C (zh) 2003-08-13
IL130622A0 (en) 2000-06-01
CA2279178A1 (en) 1998-08-06
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