CL2004000545A1 - Uso de un antagonista de los receptores de aldosterona y un antagonista de receptores de endotelina para el tratamiento o profilaxis de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopatia y enfermedades cardiovascul - Google Patents
Uso de un antagonista de los receptores de aldosterona y un antagonista de receptores de endotelina para el tratamiento o profilaxis de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopatia y enfermedades cardiovasculInfo
- Publication number
- CL2004000545A1 CL2004000545A1 CL200400545A CL2004000545A CL2004000545A1 CL 2004000545 A1 CL2004000545 A1 CL 2004000545A1 CL 200400545 A CL200400545 A CL 200400545A CL 2004000545 A CL2004000545 A CL 2004000545A CL 2004000545 A1 CL2004000545 A1 CL 2004000545A1
- Authority
- CL
- Chile
- Prior art keywords
- antagonist
- profilaxis
- endotheline
- hypertension
- pathological condition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
USO DE UNA COMBINACION DE UNO O MAS ANTAGONISTAS DE RECEPTORES DE LA ALDOSTERONA Y UNO O MAS ANTAGONISTAS DE RECEPTORES DE LA ENDOTELINA Y/O INHIBIDORES DE LA ECE SELECCIONADOS DE UN GRUPO ESPECIFICO DE COMPUESTOS QUE SE DESCRIBEN EN EL PRESENTE DOCUMENTO PARA EL TRATAMIENTO TERAPEUTICO Y/O PROFILAXIS PARA UNA CONDICION DE HIPERTENSION, ENFERMEDAD CARDIOVASCULAR, DISFUNCION RENAL, EDEMA, ENFERMEDAD CEREBROVASCULAR, O CONDICION PATOLOGICA DE INSULINOPATIA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45558003P | 2003-03-18 | 2003-03-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2004000545A1 true CL2004000545A1 (es) | 2005-01-28 |
Family
ID=33030025
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL200400545A CL2004000545A1 (es) | 2003-03-18 | 2004-03-17 | Uso de un antagonista de los receptores de aldosterona y un antagonista de receptores de endotelina para el tratamiento o profilaxis de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopatia y enfermedades cardiovascul |
Country Status (4)
Country | Link |
---|---|
US (1) | US20040186083A1 (es) |
CL (1) | CL2004000545A1 (es) |
TW (1) | TW200503730A (es) |
WO (1) | WO2004082637A2 (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1706121E (pt) * | 2004-01-12 | 2008-12-04 | Solvay Pharm Bv | Inibidores de endopeptidase neutra (nep) e endopeptidase humana solúvel (hsep) para profilaxia e tratamento de distúrbios neurodegenerativos |
US7232813B2 (en) | 2004-01-12 | 2007-06-19 | Solvay Pharmaceuticals B.V. | Neutral endopeptidase (NEP) and human soluble endopeptidase (hSEP) inhibitors for prophylaxis and treatment of neuro-degenerative disorders |
US20050288272A1 (en) * | 2004-06-23 | 2005-12-29 | Solvay Pharmaceuticals Gmbh | Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and AT1 receptor antagonists |
US7534806B2 (en) | 2004-12-06 | 2009-05-19 | Avigen, Inc. | Method for treating neuropathic pain and associated syndromes |
AR052900A1 (es) * | 2005-02-11 | 2007-04-11 | Astrazeneca Ab | Derivados de tiazol, un metodo para su preparacion, composiciones farmaceuticas que los contienen y su uso en la elaboracion de medicamentos para el tratamiento de enfermedades mediadas por ece-1 |
MY146830A (en) * | 2005-02-11 | 2012-09-28 | Novartis Ag | Combination of organic compounds |
PL1853270T3 (pl) * | 2005-02-18 | 2010-09-30 | Solvay Pharm Gmbh | Kompozycje farmaceutyczne zawierające inhibitory - NEP, inhibitory układu wytwarzającego endogenną endotelinę i diuretyki |
US20060205625A1 (en) * | 2005-02-18 | 2006-09-14 | Solvay Pharmaceuticals Gmbh | Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and diuretics |
WO2007054975A1 (en) * | 2005-11-08 | 2007-05-18 | Panacea Biotec Ltd | Pharmaceutical compositions for the treatment of cardiovascular and other associated disorders |
US20070196510A1 (en) * | 2006-02-17 | 2007-08-23 | Gerber Michael J | Method for treating resistant hypertension |
US20070232671A1 (en) * | 2006-03-13 | 2007-10-04 | Given Bruce D | Methods and compositions for treatment of diastolic heart failure |
WO2007133796A2 (en) * | 2006-05-15 | 2007-11-22 | Encysive Pharmaceuticals, Inc. | Methods and compositions for treatment of sleep apnea comprising administration of an endothelin antagonist |
CA2655144A1 (en) * | 2006-06-15 | 2007-12-21 | Gilead Colorado, Inc. | Antihypertensive therapy method |
US8080549B2 (en) | 2007-01-12 | 2011-12-20 | Concert Pharmaceuticals, Inc. | Endothelin receptor antagonists |
WO2008088727A2 (en) | 2007-01-12 | 2008-07-24 | Concert Pharmaceuticals, Inc. | Endothelin receptor antagonists |
DK2131841T3 (da) * | 2007-01-30 | 2012-10-15 | Avigen Inc | Fremgangsmåder til behandling af akut smerte |
WO2008137012A1 (en) * | 2007-05-03 | 2008-11-13 | Avigen, Inc. | Use of a glial attenuator to prevent amplified pain responses caused by glial priming |
US20090012012A1 (en) * | 2007-07-05 | 2009-01-08 | Jerome Cantor | Intratracheal administration of endothelin-suppressing agents for the treatment of respiratory disorders |
CA2904447C (en) | 2007-08-22 | 2017-01-03 | Abbvie Deutschland Gmbh & Co Kg | Therapy for complications of diabetes |
DE102011015142A1 (de) * | 2011-03-17 | 2012-09-20 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Agens zur Prophylaxe und Behandlung altersassoziierter Krankheiten und Störungen sowie zur Verlängerung der Lebensdauer |
EP2884988A4 (en) * | 2012-08-17 | 2016-04-20 | Father Flanagan S Boys Home Doing Business As Boy Town Nat Res Hospital | RAC1 INHIBITORS FOR THE TREATMENT OF GLOMEROLARY ALPORT SYNDROME |
US9719981B2 (en) | 2012-08-17 | 2017-08-01 | Father Flanagan's Boys' Home | RAC1 inhibitors for the treatment of alport glomerular disease |
JP2016521279A (ja) * | 2013-04-30 | 2016-07-21 | アッヴィ・インコーポレイテッド | アトラセンタンを使用して脂質プロファイルを改善するための方法 |
WO2017185142A1 (en) * | 2016-04-29 | 2017-11-02 | Adelaide Research & Innovation Pty Ltd | Method for preventing and/or treating atrial fibrillation |
PL424452A1 (pl) | 2018-01-31 | 2019-08-12 | Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością | Inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP) do profilaktyki i leczenia chorób oczu |
WO2023150702A2 (en) * | 2022-02-03 | 2023-08-10 | The Johns Hopkins University | Compositions and methods for treatment of connective tissue disorders |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4559332A (en) * | 1983-04-13 | 1985-12-17 | Ciba Geigy Corporation | 20-Spiroxanes and analogues having an open ring E, processes for their manufacture, and pharmaceutical preparations thereof |
US5594021A (en) * | 1993-05-20 | 1997-01-14 | Texas Biotechnology Corporation | Thienyl-, furyl- and pyrrolyl sulfonamides and derivatives thereof that modulate the activity of endothelin |
US6162927A (en) * | 1994-08-19 | 2000-12-19 | Abbott Laboratories | Endothelin antagonists |
WO1996040257A1 (en) * | 1995-06-07 | 1996-12-19 | G.D. Searle & Co. | Epoxy-steroidal aldosterone antagonist and angiotensin ii antagonist combination therapy for treatment of congestive heart failure |
US5883254A (en) * | 1996-11-08 | 1999-03-16 | Hoffmann-La Roche Inc. | Process for making pyrimidine derivatives |
TW536540B (en) * | 1997-01-30 | 2003-06-11 | Bristol Myers Squibb Co | Endothelin antagonists: N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide and N-(4,5-dimethyl-3-isoxazolyl)-2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl)methyl]-4'-(2-oxazolyl)[1,1'-biphe |
US6638937B2 (en) * | 1998-07-06 | 2003-10-28 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
-
2004
- 2004-03-17 CL CL200400545A patent/CL2004000545A1/es unknown
- 2004-03-18 TW TW093107306A patent/TW200503730A/zh unknown
- 2004-03-18 US US10/803,818 patent/US20040186083A1/en not_active Abandoned
- 2004-03-18 WO PCT/US2004/008250 patent/WO2004082637A2/en active Search and Examination
Also Published As
Publication number | Publication date |
---|---|
WO2004082637A2 (en) | 2004-09-30 |
US20040186083A1 (en) | 2004-09-23 |
WO2004082637A3 (en) | 2007-05-10 |
TW200503730A (en) | 2005-02-01 |
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