ECSP056254A - Antagonistas de receptores muscarínicos de la acetilcolina - Google Patents

Antagonistas de receptores muscarínicos de la acetilcolina

Info

Publication number
ECSP056254A
ECSP056254A EC2005006254A ECSP056254A ECSP056254A EC SP056254 A ECSP056254 A EC SP056254A EC 2005006254 A EC2005006254 A EC 2005006254A EC SP056254 A ECSP056254 A EC SP056254A EC SP056254 A ECSP056254 A EC SP056254A
Authority
EC
Ecuador
Prior art keywords
acetilcoline
muscarinic receptors
receptors antagonists
antagonists
muscarinic
Prior art date
Application number
EC2005006254A
Other languages
English (en)
Inventor
E Kristen Belmonte
Jakob Busch-Petersen
I Dramane Laine
Michael R Palovich
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ECSP056254A publication Critical patent/ECSP056254A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se proporcionan antagonistas de receptores muscarínicos de la acetilcolina y métodos de uso de los mismos.
EC2005006254A 2003-07-17 2005-12-27 Antagonistas de receptores muscarínicos de la acetilcolina ECSP056254A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48798103P 2003-07-17 2003-07-17
PCT/US2004/022947 WO2005009439A1 (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists

Publications (1)

Publication Number Publication Date
ECSP056254A true ECSP056254A (es) 2006-04-19

Family

ID=34102735

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005006254A ECSP056254A (es) 2003-07-17 2005-12-27 Antagonistas de receptores muscarínicos de la acetilcolina

Country Status (21)

Country Link
US (1) US20060178395A1 (es)
EP (1) EP1648460A4 (es)
JP (1) JP2007523877A (es)
KR (1) KR20060063890A (es)
CN (1) CN1822838A (es)
AP (1) AP2006003478A0 (es)
AR (1) AR045913A1 (es)
AU (1) AU2004259232A1 (es)
BR (1) BRPI0412716A (es)
CA (1) CA2532375A1 (es)
EA (1) EA200600267A1 (es)
EC (1) ECSP056254A (es)
IL (1) IL172822A0 (es)
IS (1) IS8302A (es)
MA (1) MA27900A1 (es)
MX (1) MXPA06000662A (es)
NO (1) NO20060775L (es)
PE (1) PE20050327A1 (es)
TW (1) TW200523261A (es)
UY (1) UY28417A1 (es)
WO (1) WO2005009439A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20050250A1 (es) * 2003-07-17 2005-04-08 Glaxo Group Ltd Antagonistas de los receptores muscarinicos de la acetilcolina
PL1677795T3 (pl) 2003-10-14 2011-05-31 Glaxo Group Ltd Antagoniści receptora muskarynowego acetylocholiny
AP2006003575A0 (en) * 2003-10-17 2006-04-30 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists.
AR046225A1 (es) * 2003-11-04 2005-11-30 Glaxo Group Ltd Compuesto de 8-azoniabiciclo(3.2.1)octano, composicion farmaceutica para el tratamiento de enfermedades mediadas por receptores de acetilcolina muscarinicos que lo comprende y uso del compuesto para preparar dicha composicion
EP1725236A4 (en) * 2004-03-11 2009-05-13 Glaxo Group Ltd NEW M3 MUSCARIN ACETYLCHOLINE RECEPTOR ANTAGONISTS
US7384946B2 (en) * 2004-03-17 2008-06-10 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
WO2005094251A2 (en) * 2004-03-17 2005-10-13 Glaxo Group Limited M3muscarinic acetylcholine receptor antagonists
TWI363759B (en) 2004-04-27 2012-05-11 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
EP1747219A4 (en) * 2004-05-13 2010-05-26 Glaxo Group Ltd Antagonists of muscarinic acetylcholine receptor
US7932247B2 (en) * 2004-11-15 2011-04-26 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
TWI268704B (en) * 2005-06-28 2006-12-11 Realtek Semiconductor Corp Apparatus and method for detecting vertical blanking interval
US20080234315A1 (en) * 2005-08-02 2008-09-25 Jakob Busch-Petersen M3 Muscarinic Acetylcholine Receptor Antagonists
CL2009000249A1 (es) 2008-02-06 2009-09-11 Glaxo Group Ltd Compuestos derivados de pirazolo[3,4-b] piridin-butanodiamida; composicion farmaceutica; y su uso en el tratamiento del asma, enfermedad pulmonar obstructiva cronica, rinitis, dermatitis atopica, psoriasis.
PE20091552A1 (es) 2008-02-06 2009-10-25 Glaxo Group Ltd Farmacoforos duales - antagonistas muscarinicos de pde4
AR070564A1 (es) 2008-02-06 2010-04-21 Glaxo Group Ltd Derivados de 1h-pirazolo[3,4-b]piridin-5-ilo,inhibidores de fosfodiesterasas pde4 y antagonistas de receptores muscarinicos de acetilcolina(machr), utiles en el tratamiento y/o profilaxis de enfermedades respiratorias y alergicas,y composiciones farmaceuticas que los comprenden
WO2010094643A1 (en) 2009-02-17 2010-08-26 Glaxo Group Limited Quinoline derivatives and their uses for rhinitis and urticaria
JP2014504260A (ja) * 2010-10-15 2014-02-20 グラクソ グループ リミテッド 集合ナノ粒子状薬物製剤、その製造及び使用
EP2836204B1 (en) 2012-04-13 2020-07-08 GlaxoSmithKline Intellectual Property Development Limited Aggregate particles
EP4125919A1 (en) 2020-03-26 2023-02-08 GlaxoSmithKline Intellectual Property Development Limited Cathepsin inhibitors for preventing or treating viral infections

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2800478A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab 3-substituted-8-alkylnortropanes and the acid and quaternary ammonium salts thereof
US2800481A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab Tertiary alcohol derivatives of 8-alkylnortropanes and the acid and quaternary ammonium salts thereof
US2800482A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab Olefinic derivatives of 8-alkylnortropanes and the acid and quaternary ammonium salts thereof
EP0944626A4 (en) * 1996-12-02 2002-09-04 Univ Georgetown TROPANE DERIVATIVES AND SYNTHESIS METHOD
US6248752B1 (en) * 1998-02-27 2001-06-19 Charles Duane Smith Azabicyclooctane compositions and methods for enhancing chemotherapy
US6262066B1 (en) * 1998-07-27 2001-07-17 Schering Corporation High affinity ligands for nociceptin receptor ORL-1
NZ513575A (en) * 1999-05-04 2003-07-25 Neurosearch As Heteroaryl diazabicycloalkanes useful for treating or preventing a disease or a disorder responsive to the activity of nAChR modulators
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
EP1302458A4 (en) * 2000-07-11 2005-10-19 Banyu Pharma Co Ltd ESTERDERIVATE
RU2004110717A (ru) * 2001-10-17 2005-10-20 Юсиби, С.А. (Be) Производные хинуклидина, способы их получения и их применение в качестве и нгибиторов м2- и/или м3- мускариновых рецепторов
CA2543858C (en) * 2003-11-21 2014-04-15 Theravance, Inc. Compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity

Also Published As

Publication number Publication date
CA2532375A1 (en) 2005-02-03
NO20060775L (no) 2006-04-11
BRPI0412716A (pt) 2006-09-26
EP1648460A4 (en) 2009-04-01
AP2006003478A0 (en) 2006-02-28
AR045913A1 (es) 2005-11-16
MA27900A1 (fr) 2006-05-02
PE20050327A1 (es) 2005-06-08
AU2004259232A1 (en) 2005-02-03
KR20060063890A (ko) 2006-06-12
EA200600267A1 (ru) 2006-06-30
MXPA06000662A (es) 2006-03-30
UY28417A1 (es) 2005-02-28
JP2007523877A (ja) 2007-08-23
CN1822838A (zh) 2006-08-23
TW200523261A (en) 2005-07-16
WO2005009439A1 (en) 2005-02-03
IS8302A (is) 2006-02-14
IL172822A0 (en) 2006-06-11
US20060178395A1 (en) 2006-08-10
EP1648460A1 (en) 2006-04-26

Similar Documents

Publication Publication Date Title
ECSP056254A (es) Antagonistas de receptores muscarínicos de la acetilcolina
CY1113295T1 (el) Ανταγωνιστες m3 μουσκαρινικου υποδοχεα ακετυλοχολινης
ECSP066468A (es) Antagonistas de receptores muscarínicos de acetilcolina
BRPI0510170A (pt) antagonistas do receptor muscarìnico de acetilcolina
UY28646A1 (es) Nuevos antagonistas del receptor muscarinico m3 de acetilcolina
UY28645A1 (es) Nuevos antagonistas del receptor muscarinico m3 de acetilcolina
ECSP066486A (es) Antagonistas de receptores de acetilcolina muscarínicos ii
UY27927A1 (es) Antagonistas del receptor muscarínico m3 de acetilcolina
CY2015029I1 (el) Τρικυκλικοι ανταγωνιστες υποδοχεα θρομβινης
TW200606161A (en) Muscarinic acetylcholine receptor antagonists
BRPI0506777A (pt) antagonistas do receptor muscarìnico da acetilcolina
NO20060777L (no) Muskarine acetylkolinreseptorantagonister
BRPI0412679A (pt) antagonistas de receptor muscarìnico de acetilcolina
UY28414A1 (es) Antagonistas de los receptores muscarinicos de la acetilcolina
UY28415A1 (es) Antagonistas de los receptores muscarinicos de la acetilcolina
UY28557A1 (es) Antagonistas de receptores de acetilcolina muscarinicos