FI941826A - Menetelmät ja koostumukset elimen hypofunktion ennaltaehkäisemiseksi ja/tai terapeuttiseksi hoitamiseksi - Google Patents

Menetelmät ja koostumukset elimen hypofunktion ennaltaehkäisemiseksi ja/tai terapeuttiseksi hoitamiseksi Download PDF

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Publication number
FI941826A
FI941826A FI941826A FI941826A FI941826A FI 941826 A FI941826 A FI 941826A FI 941826 A FI941826 A FI 941826A FI 941826 A FI941826 A FI 941826A FI 941826 A FI941826 A FI 941826A
Authority
FI
Finland
Prior art keywords
prevention
compositions
methods
therapeutic treatment
hypofunction
Prior art date
Application number
FI941826A
Other languages
English (en)
Swedish (sv)
Other versions
FI941826A0 (fi
Inventor
Toshifumi Watanabe
Mitsuhiro Wakimasu
Chieko Kitada
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FI941826A0 publication Critical patent/FI941826A0/fi
Publication of FI941826A publication Critical patent/FI941826A/fi

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
FI941826A 1993-04-21 1994-04-20 Menetelmät ja koostumukset elimen hypofunktion ennaltaehkäisemiseksi ja/tai terapeuttiseksi hoitamiseksi FI941826A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9433293 1993-04-21

Publications (2)

Publication Number Publication Date
FI941826A0 FI941826A0 (fi) 1994-04-20
FI941826A true FI941826A (fi) 1994-10-22

Family

ID=14107334

Family Applications (1)

Application Number Title Priority Date Filing Date
FI941826A FI941826A (fi) 1993-04-21 1994-04-20 Menetelmät ja koostumukset elimen hypofunktion ennaltaehkäisemiseksi ja/tai terapeuttiseksi hoitamiseksi

Country Status (5)

Country Link
US (1) US6147051A (fi)
EP (1) EP0626174A3 (fi)
CA (1) CA2121724A1 (fi)
FI (1) FI941826A (fi)
NO (1) NO941462L (fi)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962490A (en) 1987-09-25 1999-10-05 Texas Biotechnology Corporation Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
US5514696A (en) * 1992-05-06 1996-05-07 Bristol-Myers Squibb Co. Phenyl sulfonamide endothelin antagonists
US6030991A (en) * 1993-05-20 2000-02-29 Texas Biotechnology Corp. Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US6613804B2 (en) 1993-05-20 2003-09-02 Encysive Pharmaceuticals, Inc. Biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin
US6376523B1 (en) 1994-05-20 2002-04-23 Texas Biotechnology Corporation Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US6541498B2 (en) 1993-05-20 2003-04-01 Texas Biotechnology Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US6342610B2 (en) 1993-05-20 2002-01-29 Texas Biotechnology Corp. N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
GB9504854D0 (en) * 1994-03-31 1995-04-26 Zeneca Ltd Nitrogen derivatives
US5612359A (en) * 1994-08-26 1997-03-18 Bristol-Myers Squibb Company Substituted biphenyl isoxazole sulfonamides
US5760038A (en) * 1995-02-06 1998-06-02 Bristol-Myers Squibb Company Substituted biphenyl sulfonamide endothelin antagonists
US5780473A (en) * 1995-02-06 1998-07-14 Bristol-Myers Squibb Company Substituted biphenyl sulfonamide endothelin antagonists
UA58494C2 (uk) 1995-06-07 2003-08-15 Зенека Лімітед Похідні n-гетероарилпіридинсульфонаміду, фармацевтична композиція, спосіб одержання та спосіб протидії впливам ендотеліну
GB9512697D0 (en) * 1995-06-22 1995-08-23 Zeneca Ltd Heterocyclic compounds
US5846990A (en) * 1995-07-24 1998-12-08 Bristol-Myers Squibb Co. Substituted biphenyl isoxazole sulfonamides
JPH09124620A (ja) * 1995-10-11 1997-05-13 Bristol Myers Squibb Co 置換ビフェニルスルホンアミドエンドセリン拮抗剤
US5977117A (en) 1996-01-05 1999-11-02 Texas Biotechnology Corporation Substituted phenyl compounds and derivatives thereof that modulate the activity of endothelin
US5856507A (en) * 1997-01-21 1999-01-05 Bristol-Myers Squibb Co. Methods for the preparation of biphenyl isoxazole sulfonamides
SG87052A1 (en) 1996-02-20 2002-03-19 Bristol Myers Squibb Co Pinacol ester intermediates useful for the preparation of biphenyl isoxazole sulfonamides
US5939446A (en) * 1996-04-09 1999-08-17 Bristol-Myers Squibb Co. Heteroaryl substituted phenyl isoxazole sulfonamide endothelin antagonists
US5804585A (en) 1996-04-15 1998-09-08 Texas Biotechnology Corporation Thieno-pyridine sulfonamides derivatives thereof and related compounds that modulate the activity of endothelin
US6251861B1 (en) 1996-06-27 2001-06-26 Takeda Chemical Industries, Ltd. Treatment of cerebral infarction using cyclic hexapeptides
TW536540B (en) * 1997-01-30 2003-06-11 Bristol Myers Squibb Co Endothelin antagonists: N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide and N-(4,5-dimethyl-3-isoxazolyl)-2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl)methyl]-4'-(2-oxazolyl)[1,1'-biphe
WO1998033781A1 (en) * 1997-01-30 1998-08-06 Bristol-Myers Squibb Company Method for preventing or treating low renin hypertension by administering an endothelin antagonist
US5783705A (en) 1997-04-28 1998-07-21 Texas Biotechnology Corporation Process of preparing alkali metal salys of hydrophobic sulfonamides
JP3455233B2 (ja) 1997-04-28 2003-10-14 テキサス・バイオテクノロジー・コーポレイシヨン エンドテリン介在障害治療用のスルホンアミド類
DE19743681A1 (de) * 1997-10-02 1999-04-08 Knoll Ag Methode zur Verhinderung der Transplantatabstoßung
MXPA01009362A (es) 1999-03-19 2002-06-04 Squibb Bristol Myers Co Metodos para la preparacion de bifenil isoxazol sulfonamidas.
WO2003006041A1 (fr) * 2001-07-12 2003-01-23 Takeda Chemical Industries, Ltd. Agents prophylactiques/therapeutiques contre les tumeurs malignes
WO2003024932A1 (en) 2001-09-18 2003-03-27 Bristol-Myers Squibb Company Bis-amino acid sulfonamides as hiv protease inhibitors
SI1664050T1 (sl) * 2003-09-03 2016-04-29 Neuren Pharmaceuticals Limited Nevroprotektične biciklične spojine in farmacevtski sestavki, vsebujoči le-te
GB201810581D0 (en) 2018-06-28 2018-08-15 Ctxt Pty Ltd Compounds
AU2020296361A1 (en) 2019-06-18 2022-01-06 Ctxt Pty Ltd Benzisoxazole sulfonamide derivatives

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3650649T2 (de) 1985-07-08 1998-02-12 Energy Conversion Devices Inc Datenaufzeichnungsgerät und Verfahren zur Datenverarbeitung
JP3061631B2 (ja) * 1989-10-11 2000-07-10 山之内製薬株式会社 新規なヘテロ環化合物およびその製造法
CA2032559C (en) 1989-12-28 2001-11-06 Kiyofumi Ishikawa Endothelin antagonistic cyclic pentapeptides
CA2053895A1 (en) 1990-02-26 1991-08-27 Mitsuhiro Wakimasu Peptide derivatives and production thereof
JPH05503105A (ja) 1990-02-26 1993-05-27 武田薬品工業株式会社 ペプチド誘導体およびその製造法
US5214130A (en) * 1990-02-27 1993-05-25 Merck & Co., Inc. Synthesis of novel immunosuppressive cyclosporin analogs with modified amino acids at position-8
US5284828A (en) 1990-05-14 1994-02-08 Fujisawa Pharmaceutical Co. Ltd. Peptide compound and its preparation
JPH0427785A (ja) 1990-05-23 1992-01-30 Kayaba Ind Co Ltd 2連型ベーンポンプ
CA2043741C (en) 1990-06-07 2003-04-01 Kiyofumi Ishikawa Endothelin antagonistic peptide derivatives
GB9100721D0 (en) 1991-01-12 1991-02-27 Japat Ltd Endothelin antagonists
CA2059380A1 (en) 1991-01-24 1992-07-25 Yiu-Kuen T. Lam Endothelin receptor antagonists isolated from microbispora
ES2115665T3 (es) 1991-01-29 1998-07-01 Shionogi & Co Derivado de triterpeno.
ES2089256T3 (es) 1991-02-15 1996-10-01 Takeda Chemical Industries Ltd Antagonista de la endotelina.
TW270116B (fi) 1991-04-25 1996-02-11 Hoffmann La Roche
DE69231404T2 (de) 1991-05-16 2001-02-08 Warner Lambert Co Endothelinantagonisten
RU2086544C1 (ru) 1991-06-13 1997-08-10 Хоффманн-Ля Рош АГ Бензолсульфонамидные производные пиримидина или их соли, фармацевтическая композиция для лечения заболеваний, связанных с активностью эндотелина
EP0528312B1 (en) 1991-08-13 1997-07-16 Takeda Chemical Industries, Ltd. Cyclic peptides and use thereof
AU669866B2 (en) 1991-11-05 1996-06-27 Smithkline Beecham Corporation Endothelin receptor antagonists
TW217417B (fi) 1991-12-04 1993-12-11 Manyu Seiyaku Kk
JPH05178890A (ja) 1991-12-26 1993-07-20 Banyu Pharmaceut Co Ltd エンドセリン拮抗性化合物
JPH06172384A (ja) 1991-12-27 1994-06-21 Takeda Chem Ind Ltd ペプチド、その製造法および用途
US5614497A (en) 1991-12-27 1997-03-25 Takeda Chemical Industries, Ltd. Peptide, production and use thereof
CA2104952A1 (en) 1991-12-27 1993-06-28 Takeo Tanaka Endothelin-antagonizing peptide
JPH05279390A (ja) 1992-02-06 1993-10-26 Banyu Pharmaceut Co Ltd エンドセリン拮抗性環状ペンタペプチド
TW224462B (fi) 1992-02-24 1994-06-01 Squibb & Sons Inc
WO1993017701A1 (en) 1992-03-12 1993-09-16 The Administrators Of The Tulane Educational Fund Endothelin receptor-binding peptides
US5240910A (en) * 1992-04-17 1993-08-31 Merck & Co., Inc. Antihypertensive compounds produced by fermentation
CZ256994A3 (en) 1992-04-22 1995-02-15 Warner Lambert Co Peptides, process of their preparation and pharmaceutical compositions based thereof
US5514696A (en) * 1992-05-06 1996-05-07 Bristol-Myers Squibb Co. Phenyl sulfonamide endothelin antagonists
NZ247440A (en) 1992-05-06 1995-04-27 Squibb & Sons Inc Phenyl sulphonamide derivatives, preparation and pharmaceutical compositions thereof
WO1993023404A1 (en) 1992-05-19 1993-11-25 Immunopharmaceutics, Inc. Compounds that modulate endothelin activity
ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
TW299333B (fi) * 1992-12-29 1997-03-01 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
CA2121724A1 (en) 1994-10-22
EP0626174A3 (en) 1996-01-03
NO941462D0 (no) 1994-04-21
EP0626174A2 (en) 1994-11-30
NO941462L (no) 1994-10-24
FI941826A0 (fi) 1994-04-20
US6147051A (en) 2000-11-14

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