NO970385D0 - Analogifremgangsmåte for fremstilling av et terapautisk aktivt nukleosid - Google Patents
Analogifremgangsmåte for fremstilling av et terapautisk aktivt nukleosidInfo
- Publication number
- NO970385D0 NO970385D0 NO970385A NO970385A NO970385D0 NO 970385 D0 NO970385 D0 NO 970385D0 NO 970385 A NO970385 A NO 970385A NO 970385 A NO970385 A NO 970385A NO 970385 D0 NO970385 D0 NO 970385D0
- Authority
- NO
- Norway
- Prior art keywords
- bch
- preparation
- therapeutically active
- analogous process
- active nucleoside
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Steroid Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO20083728A NO20083728L (no) | 1990-02-01 | 2008-08-28 | Analogifremgangsmate for fremstilling av et terapeutisk aktivt nukleosid |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/473,318 US5204466A (en) | 1990-02-01 | 1990-02-01 | Method and compositions for the synthesis of bch-189 and related compounds |
PCT/US1991/000685 WO1991011186A1 (en) | 1990-02-01 | 1991-01-31 | Method and compositions for the synthesis of bch-189 and related compounds |
Publications (3)
Publication Number | Publication Date |
---|---|
NO970385L NO970385L (no) | 1992-07-30 |
NO970385D0 true NO970385D0 (no) | 1997-01-29 |
NO324979B1 NO324979B1 (no) | 2008-01-14 |
Family
ID=23879071
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO923014A NO923014D0 (no) | 1990-02-01 | 1992-07-30 | Fremgangsmaate og preparat for syntese av bch-189 og relaterte forbindelser |
NO19970386A NO313048B1 (no) | 1990-02-01 | 1997-01-29 | Fremgangsmåte for fremstilling av et terapeutisk aktivt racemisk cis-1,3-oksatiolan |
NO19970385A NO324979B1 (no) | 1990-02-01 | 1997-01-29 | Analogifremgangsmate for fremstilling av et terapeutisk aktivt nukleosid |
NO20065640A NO326249B1 (no) | 1990-02-01 | 2006-12-07 | Fremgangsmate for fremstilling av en nukleosidsammensetning omfattende et 2`,3`-dideoksy-3`-tiapyrimidinnukleosid, mellomprodukter for anvendelse i fremgangsmaten samt fremgangsmate for fremstilling av mellomprodukt |
NO2008011C NO2008011I2 (no) | 1990-02-01 | 2008-07-11 | Emtricitabin (5-fluor-1-(2R,5S)-[2-(hydroksymetyl)-1,3-oksotiolan-5-y]ytosin |
NO20083728A NO20083728L (no) | 1990-02-01 | 2008-08-28 | Analogifremgangsmate for fremstilling av et terapeutisk aktivt nukleosid |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO923014A NO923014D0 (no) | 1990-02-01 | 1992-07-30 | Fremgangsmaate og preparat for syntese av bch-189 og relaterte forbindelser |
NO19970386A NO313048B1 (no) | 1990-02-01 | 1997-01-29 | Fremgangsmåte for fremstilling av et terapeutisk aktivt racemisk cis-1,3-oksatiolan |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20065640A NO326249B1 (no) | 1990-02-01 | 2006-12-07 | Fremgangsmate for fremstilling av en nukleosidsammensetning omfattende et 2`,3`-dideoksy-3`-tiapyrimidinnukleosid, mellomprodukter for anvendelse i fremgangsmaten samt fremgangsmate for fremstilling av mellomprodukt |
NO2008011C NO2008011I2 (no) | 1990-02-01 | 2008-07-11 | Emtricitabin (5-fluor-1-(2R,5S)-[2-(hydroksymetyl)-1,3-oksotiolan-5-y]ytosin |
NO20083728A NO20083728L (no) | 1990-02-01 | 2008-08-28 | Analogifremgangsmate for fremstilling av et terapeutisk aktivt nukleosid |
Country Status (22)
Country | Link |
---|---|
US (8) | US5204466A (no) |
EP (3) | EP1772151A3 (no) |
JP (6) | JPH07618B2 (no) |
KR (2) | KR100188357B1 (no) |
AT (1) | ATE170750T1 (no) |
AU (6) | AU658136C (no) |
BG (1) | BG62236B1 (no) |
CA (3) | CA2075189C (no) |
DE (4) | DE122004000015I2 (no) |
DK (2) | DK0513200T4 (no) |
ES (2) | ES2076130T5 (no) |
FI (4) | FI114471B (no) |
GR (1) | GR950300024T1 (no) |
HK (1) | HK1014664A1 (no) |
HU (4) | HU227485B1 (no) |
LU (1) | LU91073I2 (no) |
MC (1) | MC2233A1 (no) |
NL (1) | NL300148I2 (no) |
NO (6) | NO923014D0 (no) |
RO (1) | RO108564B1 (no) |
RU (1) | RU2125558C1 (no) |
WO (1) | WO1991011186A1 (no) |
Families Citing this family (150)
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US5047407A (en) | 1989-02-08 | 1991-09-10 | Iaf Biochem International, Inc. | 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties |
US5684164A (en) * | 1988-04-11 | 1997-11-04 | Biochem Pharma Inc. | Processes for preparing substituted 1,3-oxathiolanes with antiviral properties |
US5466806A (en) * | 1989-02-08 | 1995-11-14 | Biochem Pharma Inc. | Processes for preparing substituted 1,3-oxathiolanes with antiviral properties |
US6350753B1 (en) | 1988-04-11 | 2002-02-26 | Biochem Pharma Inc. | 2-Substituted-4-substituted-1,3-dioxolanes and use thereof |
AU3154993A (en) * | 1989-02-08 | 1994-07-19 | Biochem Pharma Inc. | Process for preparing substituted 1,3-oxathiolanes with antiviral properties |
US5204466A (en) * | 1990-02-01 | 1993-04-20 | Emory University | Method and compositions for the synthesis of bch-189 and related compounds |
US6703396B1 (en) * | 1990-02-01 | 2004-03-09 | Emory University | Method of resolution and antiviral activity of 1,3-oxathiolane nuclesoside enantiomers |
US20090239887A1 (en) * | 1990-02-01 | 2009-09-24 | Emory University | Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers |
US6069252A (en) * | 1990-02-01 | 2000-05-30 | Emory University | Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers |
US6642245B1 (en) | 1990-02-01 | 2003-11-04 | Emory University | Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane |
US5276151A (en) * | 1990-02-01 | 1994-01-04 | Emory University | Method of synthesis of 1,3-dioxolane nucleosides |
GB9009861D0 (en) * | 1990-05-02 | 1990-06-27 | Glaxo Group Ltd | Chemical compounds |
US5444063A (en) * | 1990-12-05 | 1995-08-22 | Emory University | Enantiomerically pure β-D-dioxolane nucleosides with selective anti-Hepatitis B virus activity |
US5925643A (en) * | 1990-12-05 | 1999-07-20 | Emory University | Enantiomerically pure β-D-dioxolane-nucleosides |
IL100502A (en) * | 1991-01-03 | 1995-12-08 | Iaf Biochem Int | PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (- |
IL100965A (en) * | 1991-02-22 | 1999-12-31 | Univ Emory | 2 - Hydroxymethyl - 5 -) 5 - Fluorocytocin - 1 - Eyal (- 1, 3 - Oxathiolane, its resolution and pharmaceuticals containing it |
GB9104740D0 (en) * | 1991-03-06 | 1991-04-17 | Wellcome Found | Antiviral nucleoside combination |
KR100270806B1 (ko) * | 1991-03-06 | 2000-11-01 | 템블 존 엘 | 5-플루오로-2`-데옥시-3`-티아시티딘을 함유하는 b형 간염 치료를 위한 약제 |
US6812233B1 (en) * | 1991-03-06 | 2004-11-02 | Emory University | Therapeutic nucleosides |
US5817667A (en) * | 1991-04-17 | 1998-10-06 | University Of Georgia Research Foudation | Compounds and methods for the treatment of cancer |
GB9109506D0 (en) * | 1991-05-02 | 1991-06-26 | Wellcome Found | Therapeutic nucleosides |
GB9110874D0 (en) * | 1991-05-20 | 1991-07-10 | Iaf Biochem Int | Medicaments |
ZA923640B (en) * | 1991-05-21 | 1993-02-24 | Iaf Biochem Int | Processes for the diastereoselective synthesis of nucleosides |
GB9111902D0 (en) * | 1991-06-03 | 1991-07-24 | Glaxo Group Ltd | Chemical compounds |
GB9116601D0 (en) * | 1991-08-01 | 1991-09-18 | Iaf Biochem Int | 1,3-oxathiolane nucleoside analogues |
US20050192299A1 (en) * | 1992-04-16 | 2005-09-01 | Yung-Chi Cheng | Method of treating or preventing hepatitis B virus |
GB9311709D0 (en) * | 1993-06-07 | 1993-07-21 | Iaf Biochem Int | Stereoselective synthesis of nucleoside analogues using bicycle intermediate |
US20020120130A1 (en) * | 1993-09-10 | 2002-08-29 | Gilles Gosselin | 2' or 3' -deoxy and 2', 3' -dideoxy-beta-L-pentofuranonucleo-side compounds, method of preparation and application in therapy, especially as anti- viral agents |
CA2171550C (en) * | 1993-09-10 | 2008-08-26 | Raymond F. Schinazi | Nucleosides with anti-hepatitis b virus activity |
US5587362A (en) * | 1994-01-28 | 1996-12-24 | Univ. Of Ga Research Foundation | L-nucleosides |
IL113432A (en) * | 1994-04-23 | 2000-11-21 | Glaxo Group Ltd | Process for the diastereoselective synthesis of nucleoside analogues |
IL115156A (en) * | 1994-09-06 | 2000-07-16 | Univ Georgia | Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines |
US5703058A (en) * | 1995-01-27 | 1997-12-30 | Emory University | Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent |
US6391859B1 (en) | 1995-01-27 | 2002-05-21 | Emory University | [5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides |
US5808040A (en) * | 1995-01-30 | 1998-09-15 | Yale University | L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides |
US6689761B1 (en) | 1995-02-01 | 2004-02-10 | Merck & Co., Inc. | Combination therapy for HIV infection |
MY115461A (en) | 1995-03-30 | 2003-06-30 | Wellcome Found | Synergistic combinations of zidovudine, 1592u89 and 3tc |
GB9506644D0 (en) * | 1995-03-31 | 1995-05-24 | Wellcome Found | Preparation of nucleoside analogues |
DE19514523A1 (de) * | 1995-04-12 | 1996-10-17 | Schering Ag | Neue Cytosin- und Cytidinderivate |
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KR100954390B1 (ko) | 1998-02-25 | 2010-04-26 | 에모리 유니버시티 | 2'-플루오로뉴클레오사이드 |
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2003
- 2003-06-24 FI FI20030933A patent/FI116222B/fi active IP Right Grant
- 2003-11-03 US US10/700,276 patent/US20050004148A1/en not_active Abandoned
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2004
- 2004-04-23 NL NL300148C patent/NL300148I2/nl unknown
- 2004-05-17 JP JP2004146115A patent/JP4108645B2/ja not_active Expired - Lifetime
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2005
- 2005-06-22 FI FI20050672A patent/FI121069B/fi active IP Right Grant
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2006
- 2006-02-10 JP JP2006033782A patent/JP4496377B2/ja not_active Expired - Lifetime
- 2006-06-27 FI FI20060622A patent/FI20060622A/fi not_active Application Discontinuation
- 2006-09-07 AU AU2006207874A patent/AU2006207874B2/en not_active Expired
- 2006-12-07 NO NO20065640A patent/NO326249B1/no not_active IP Right Cessation
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2008
- 2008-07-11 NO NO2008011C patent/NO2008011I2/no unknown
- 2008-08-28 NO NO20083728A patent/NO20083728L/no unknown
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2010
- 2010-05-10 AU AU2010201878A patent/AU2010201878A1/en not_active Abandoned
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