NO328377B1 - Humanisert, monoklonalt antistoff som binder ErbB2/HER2, farmasoytisk formulering, immunkonjugat, isolert nukleinsyre, vektor, vertscelle og fremgangsmate for fremstilling av antistoff. - Google Patents
Humanisert, monoklonalt antistoff som binder ErbB2/HER2, farmasoytisk formulering, immunkonjugat, isolert nukleinsyre, vektor, vertscelle og fremgangsmate for fremstilling av antistoff. Download PDFInfo
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- NO328377B1 NO328377B1 NO20016329A NO20016329A NO328377B1 NO 328377 B1 NO328377 B1 NO 328377B1 NO 20016329 A NO20016329 A NO 20016329A NO 20016329 A NO20016329 A NO 20016329A NO 328377 B1 NO328377 B1 NO 328377B1
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- UGGWPQSBPIFKDZ-KOTLKJBCSA-N vindesine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(N)=O)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1N=C1[C]2C=CC=C1 UGGWPQSBPIFKDZ-KOTLKJBCSA-N 0.000 description 1
- GBABOYUKABKIAF-IELIFDKJSA-N vinorelbine Chemical compound C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC GBABOYUKABKIAF-IELIFDKJSA-N 0.000 description 1
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
- A61K47/6809—Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
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- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Packages (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US14131699P | 1999-06-25 | 1999-06-25 | |
PCT/US2000/017366 WO2001000245A2 (en) | 1999-06-25 | 2000-06-23 | HUMANIZED ANTI-ErbB2 ANTIBODIES AND TREATMENT WITH ANTI-ErbB2 ANTIBODIES |
Publications (3)
Publication Number | Publication Date |
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NO20016329D0 NO20016329D0 (no) | 2001-12-21 |
NO20016329L NO20016329L (no) | 2002-02-25 |
NO328377B1 true NO328377B1 (no) | 2010-02-08 |
Family
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Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
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NO20016329A NO328377B1 (no) | 1999-06-25 | 2001-12-21 | Humanisert, monoklonalt antistoff som binder ErbB2/HER2, farmasoytisk formulering, immunkonjugat, isolert nukleinsyre, vektor, vertscelle og fremgangsmate for fremstilling av antistoff. |
NO20091792A NO336040B1 (no) | 1999-06-25 | 2009-05-05 | Anvendelse av antistoff som binder til ErbB2 og blokkerer ligandaktivering av en ErbB2-reseptor, for fremstilling av et medikament for behandling av kreft hos et menneske, anvendelse av rhuMAb 2C4 for fremstilling av et medikament for behandling av kreft, humanisert antistoff, immunkonjugat, affinitetsmodnet antistoff |
NO2013005C NO2013005I1 (no) | 1999-06-25 | 2013-03-12 | Pertuzumab |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20091792A NO336040B1 (no) | 1999-06-25 | 2009-05-05 | Anvendelse av antistoff som binder til ErbB2 og blokkerer ligandaktivering av en ErbB2-reseptor, for fremstilling av et medikament for behandling av kreft hos et menneske, anvendelse av rhuMAb 2C4 for fremstilling av et medikament for behandling av kreft, humanisert antistoff, immunkonjugat, affinitetsmodnet antistoff |
NO2013005C NO2013005I1 (no) | 1999-06-25 | 2013-03-12 | Pertuzumab |
Country Status (33)
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EP (2) | EP1189641B1 (xx) |
JP (2) | JP4283474B2 (xx) |
KR (2) | KR100850389B1 (xx) |
CN (4) | CN100340575C (xx) |
AR (1) | AR024464A1 (xx) |
AT (2) | AT500848B1 (xx) |
AU (2) | AU784045B2 (xx) |
BE (1) | BE2013C020I2 (xx) |
BR (2) | BRPI0012198B8 (xx) |
CA (2) | CA2727172A1 (xx) |
CH (1) | CH694589A5 (xx) |
CY (2) | CY1109525T1 (xx) |
CZ (1) | CZ299702B6 (xx) |
DE (2) | DE60042648D1 (xx) |
DK (1) | DK1189641T5 (xx) |
ES (1) | ES2329437T3 (xx) |
FR (1) | FR13C0016I2 (xx) |
GB (1) | GB2368796B (xx) |
GE (1) | GEP20104998B (xx) |
HK (1) | HK1044888A1 (xx) |
HU (1) | HU226742B1 (xx) |
IL (3) | IL146954A0 (xx) |
LU (1) | LU92164I2 (xx) |
MX (1) | MXPA01013458A (xx) |
NO (3) | NO328377B1 (xx) |
NZ (2) | NZ531426A (xx) |
PL (2) | PL203326B1 (xx) |
PT (1) | PT1189641E (xx) |
RU (2) | RU2270029C2 (xx) |
SI (3) | SI2283867T1 (xx) |
TR (1) | TR200103756T2 (xx) |
WO (1) | WO2001000245A2 (xx) |
ZA (2) | ZA200109786B (xx) |
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