NO323698B1 - C-aryl-glukosid-SGLT2-inhibitorer, farmasoytiske blandinger og kombinasjoner inneholdende disse, anvendelse av disse for fremstilling av farmasoytisk preparat til behandling samt et mellomprodukt for fremstilling. - Google Patents
C-aryl-glukosid-SGLT2-inhibitorer, farmasoytiske blandinger og kombinasjoner inneholdende disse, anvendelse av disse for fremstilling av farmasoytisk preparat til behandling samt et mellomprodukt for fremstilling. Download PDFInfo
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- NO323698B1 NO323698B1 NO20021721A NO20021721A NO323698B1 NO 323698 B1 NO323698 B1 NO 323698B1 NO 20021721 A NO20021721 A NO 20021721A NO 20021721 A NO20021721 A NO 20021721A NO 323698 B1 NO323698 B1 NO 323698B1
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- agent
- inhibitor
- alkyl
- mmol
- compounds
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Classifications
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- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
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US15877399P | 1999-10-12 | 1999-10-12 | |
US19461500P | 2000-04-05 | 2000-04-05 | |
PCT/US2000/027187 WO2001027128A1 (en) | 1999-10-12 | 2000-10-02 | C-aryl glucoside sglt2 inhibitors |
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NO20021721D0 NO20021721D0 (no) | 2002-04-11 |
NO20021721L NO20021721L (no) | 2002-06-10 |
NO323698B1 true NO323698B1 (no) | 2007-06-25 |
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NO20021721A NO323698B1 (no) | 1999-10-12 | 2002-04-11 | C-aryl-glukosid-SGLT2-inhibitorer, farmasoytiske blandinger og kombinasjoner inneholdende disse, anvendelse av disse for fremstilling av farmasoytisk preparat til behandling samt et mellomprodukt for fremstilling. |
NO20070149A NO332798B1 (no) | 1999-10-12 | 2007-01-09 | Mellomprodukter for syntese av C-aryl-glukosid-SGLT2-inhibitorer |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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NO20070149A NO332798B1 (no) | 1999-10-12 | 2007-01-09 | Mellomprodukter for syntese av C-aryl-glukosid-SGLT2-inhibitorer |
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US (1) | US6414126B1 (zh) |
EP (1) | EP1224195B1 (zh) |
JP (1) | JP4365554B2 (zh) |
KR (1) | KR100728085B1 (zh) |
CN (1) | CN1284793C (zh) |
AR (1) | AR026024A1 (zh) |
AT (1) | ATE295848T1 (zh) |
AU (1) | AU781009B2 (zh) |
BR (2) | BR0014722A (zh) |
CA (1) | CA2388818C (zh) |
CO (1) | CO5251414A1 (zh) |
CZ (1) | CZ304522B6 (zh) |
DE (1) | DE60020259T2 (zh) |
EG (1) | EG24515A (zh) |
ES (1) | ES2240179T3 (zh) |
HK (1) | HK1044541B (zh) |
HU (2) | HU230727B1 (zh) |
IL (2) | IL148806A0 (zh) |
IN (1) | IN2007MU00019A (zh) |
MX (1) | MX237254B (zh) |
MY (1) | MY125405A (zh) |
NO (2) | NO323698B1 (zh) |
NZ (1) | NZ518029A (zh) |
PE (1) | PE20011000A1 (zh) |
PH (1) | PH12000002657B1 (zh) |
PL (1) | PL204358B1 (zh) |
PT (1) | PT1224195E (zh) |
RU (1) | RU2262507C2 (zh) |
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TW (1) | TWI254714B (zh) |
UY (1) | UY26391A1 (zh) |
WO (1) | WO2001027128A1 (zh) |
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CN1020944C (zh) | 1990-01-30 | 1993-05-26 | 阿图尔-费希尔股份公司费希尔厂 | 紧固件 |
US6515117B2 (en) * | 1999-10-12 | 2003-02-04 | Bristol-Myers Squibb Company | C-aryl glucoside SGLT2 inhibitors and method |
EP1258249B1 (en) * | 1999-12-28 | 2005-11-23 | Ajinomoto Co., Inc. | Oral preparations for diabetes |
US6627611B2 (en) * | 2000-02-02 | 2003-09-30 | Kotobuki Pharmaceutical Co Ltd | C-glycosides and preparation of thereof as antidiabetic agents |
FR2809310B1 (fr) * | 2000-05-26 | 2004-02-13 | Centre Nat Rech Scient | Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant |
AU2002253838B2 (en) * | 2000-10-30 | 2006-11-09 | Ortho-Mcneil Pharmaceutical, Inc. | Combination therapy comprising anti-diabetic and anticonvulsant agents |
US6555581B1 (en) | 2001-02-15 | 2003-04-29 | Jones Pharma, Inc. | Levothyroxine compositions and methods |
BR0207297A (pt) * | 2001-02-15 | 2005-04-19 | King Pharmaceuticals Inc | Composição farmacêutica em forma sólida e método de preparar uma forma de dosagem sólida de um ingrediente farmaceuticamente ativo |
US20030032675A1 (en) * | 2001-02-15 | 2003-02-13 | Franz G. Andrew | Manufacture of thyroid hormone tablets having consistent active moiety amounts |
US20030224047A1 (en) * | 2001-02-15 | 2003-12-04 | Franz G. Andrew | Levothyroxine compositions and methods |
US6936590B2 (en) * | 2001-03-13 | 2005-08-30 | Bristol Myers Squibb Company | C-aryl glucoside SGLT2 inhibitors and method |
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