ATE504591T1 - Neue phosphorhaltige heterocyclische verbindungen,zuckeranaloga und zusammensetzungen mit antikrebswirkung, die diese enthalten - Google Patents

Neue phosphorhaltige heterocyclische verbindungen,zuckeranaloga und zusammensetzungen mit antikrebswirkung, die diese enthalten

Info

Publication number
ATE504591T1
ATE504591T1 AT08774839T AT08774839T ATE504591T1 AT E504591 T1 ATE504591 T1 AT E504591T1 AT 08774839 T AT08774839 T AT 08774839T AT 08774839 T AT08774839 T AT 08774839T AT E504591 T1 ATE504591 T1 AT E504591T1
Authority
AT
Austria
Prior art keywords
compositions
heterocyclic compounds
cancer activity
novel phosphorus
sugar analogues
Prior art date
Application number
AT08774839T
Other languages
English (en)
Inventor
Jean-Luc Pirat
David Virieux
Ludovic Clarion
Jean-Noel Volle
Norbert Bakalara
Marcel Mersel
Jerome Montbrun
Henri-Jean Cristau
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE504591T1 publication Critical patent/ATE504591T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657172Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and one oxygen atom being part of a (thio)phosphinic acid ester: (X = O, S)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT08774839T 2007-07-05 2008-07-07 Neue phosphorhaltige heterocyclische verbindungen,zuckeranaloga und zusammensetzungen mit antikrebswirkung, die diese enthalten ATE504591T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94814307P 2007-07-05 2007-07-05
PCT/EP2008/058788 WO2009004096A1 (en) 2007-07-05 2008-07-07 New phosphorus containing heterocyclic compounds, sugar analogues, and compositions having anti-cancer activity containing the same

Publications (1)

Publication Number Publication Date
ATE504591T1 true ATE504591T1 (de) 2011-04-15

Family

ID=39790257

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08774839T ATE504591T1 (de) 2007-07-05 2008-07-07 Neue phosphorhaltige heterocyclische verbindungen,zuckeranaloga und zusammensetzungen mit antikrebswirkung, die diese enthalten

Country Status (5)

Country Link
US (1) US8383609B2 (de)
EP (1) EP2170912B3 (de)
AT (1) ATE504591T1 (de)
DE (1) DE602008006081D1 (de)
WO (1) WO2009004096A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3002451B1 (fr) 2013-02-25 2015-06-26 Centre Nat Rech Scient Heterocycles phosphores analogues de sucres a activite antimetastatique
FR3050732B1 (fr) * 2016-05-02 2019-06-28 Institut National De La Sante Et De La Recherche Medicale (Inserm) Nouveaux derives de phosphinolactones et leurs utilisations pharmaceutiques
EP3295944A1 (de) 2016-09-20 2018-03-21 Phost'in Kristalline polymorphe form von 3-hydroxy-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenyl-2-oxo-2lambda5-[1,2]oxaphosphinan
TW202237093A (zh) 2021-01-13 2022-10-01 法商弗斯汀治療公司 治療纖維化疾病的方法
US20250325570A1 (en) 2022-05-20 2025-10-23 Phost'in Therapeutics Dose and regimen for a heterocyclic phosphinic compound
WO2025132992A1 (en) 2023-12-20 2025-06-26 Phost'in Therapeutics DEUTERATED DERIVATIVES OF 3-HYDROXY-4,5-BIS-BENZYLOXY-6-BENZYLOXYMETHYL-2-PHENYL-2-OXO-2λ5-[1,2]OXAPHOSPHINANE
WO2025160705A1 (zh) * 2024-01-29 2025-08-07 维眸生物科技(浙江)有限公司 一种lfa-1抑制剂的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6024998A (en) 1997-01-15 1998-08-07 Glycomed Incorporated Aryl c-glycoside compounds and sulfated esters thereof
PH12000002657B1 (en) 1999-10-12 2006-02-21 Bristol Myers Squibb Co C-aryl glucoside SGLT2 inhibitors

Also Published As

Publication number Publication date
WO2009004096A1 (en) 2009-01-08
EP2170912B3 (de) 2022-06-15
US8383609B2 (en) 2013-02-26
US20100298272A1 (en) 2010-11-25
DE602008006081D1 (de) 2011-05-19
EP2170912A1 (de) 2010-04-07
EP2170912B1 (de) 2011-04-06

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