NO2227271T3 - - Google Patents
Info
- Publication number
- NO2227271T3 NO2227271T3 NO08857318A NO08857318A NO2227271T3 NO 2227271 T3 NO2227271 T3 NO 2227271T3 NO 08857318 A NO08857318 A NO 08857318A NO 08857318 A NO08857318 A NO 08857318A NO 2227271 T3 NO2227271 T3 NO 2227271T3
- Authority
- NO
- Norway
- Prior art keywords
- cells
- sample
- tubing set
- separation column
- container
- Prior art date
Links
- 210000004027 cell Anatomy 0.000 abstract 11
- 238000000926 separation method Methods 0.000 abstract 4
- 210000000601 blood cell Anatomy 0.000 abstract 1
- 230000036512 infertility Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4621—Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
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- A—HUMAN NECESSITIES
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- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
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- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/46433—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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- A61K39/46434—Antigens related to induction of tolerance to non-self
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- A—HUMAN NECESSITIES
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- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
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- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3861—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36 using an external stimulus
- B01D15/3885—Using electrical or magnetic means
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
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- B03C1/002—High gradient magnetic separation
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B03C1/025—High gradient magnetic separators
- B03C1/027—High gradient magnetic separators with reciprocating canisters
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
- B03C1/031—Component parts; Auxiliary operations
- B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
- B03C1/0332—Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
- B03C1/031—Component parts; Auxiliary operations
- B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
- B03C1/0335—Component parts; Auxiliary operations characterised by the magnetic circuit using coils
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B03C1/031—Component parts; Auxiliary operations
- B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
- B03C1/034—Component parts; Auxiliary operations characterised by the magnetic circuit characterised by the matrix elements
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- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
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- B04B1/10—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles with discharging outlets in the plane of the maximum diameter of the bowl
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- C12M23/00—Constructional details, e.g. recesses, hinges
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- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
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Families Citing this family (295)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITBO20050481A1 (it) | 2005-07-19 | 2007-01-20 | Silicon Biosystems S R L | Metodo ed apparato per la manipolazione e/o l'individuazione di particelle |
ITBO20050646A1 (it) | 2005-10-26 | 2007-04-27 | Silicon Biosystem S R L | Metodo ed apparato per la caratterizzazione ed il conteggio di particelle |
ITTO20060226A1 (it) | 2006-03-27 | 2007-09-28 | Silicon Biosystem S P A | Metodo ed apparato per il processamento e o l'analisi e o la selezione di particelle, in particolare particelle biologiche |
ITTO20070771A1 (it) | 2007-10-29 | 2009-04-30 | Silicon Biosystems Spa | Metodo e apparato per la identificazione e manipolazione di particelle |
ES2660180T3 (es) | 2007-12-07 | 2018-03-21 | Miltenyi Biotec Gmbh | Sistemas y métodos para procesamiento de células |
US10895575B2 (en) | 2008-11-04 | 2021-01-19 | Menarini Silicon Biosystems S.P.A. | Method for identification, selection and analysis of tumour cells |
IT1391619B1 (it) | 2008-11-04 | 2012-01-11 | Silicon Biosystems Spa | Metodo per l'individuazione, selezione e analisi di cellule tumorali |
US9192943B2 (en) * | 2009-03-17 | 2015-11-24 | Silicon Biosystems S.P.A. | Microfluidic device for isolation of cells |
US9476812B2 (en) | 2010-04-21 | 2016-10-25 | Dna Electronics, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
US20110262989A1 (en) | 2010-04-21 | 2011-10-27 | Nanomr, Inc. | Isolating a target analyte from a body fluid |
US8852532B2 (en) * | 2010-06-18 | 2014-10-07 | Roche Diagnostics Operations, Inc. | G-force sensitive label and corresponding sample tube, method and analytical system |
US8870733B2 (en) * | 2010-11-19 | 2014-10-28 | Kensey Nash Corporation | Centrifuge |
RU2553285C2 (ru) * | 2010-11-23 | 2015-06-10 | Химонетикс Корпорейшн | Ротор для афереза с улучшенными вибрационными характеристиками |
CA2819260A1 (en) | 2010-12-15 | 2012-06-21 | Cytosed, Inc. | Antibody-linked immuno-sedimentation agent and method of isolating a target from a sample using same |
US9404864B2 (en) | 2013-03-13 | 2016-08-02 | Denovo Sciences, Inc. | System for imaging captured cells |
CN103998394B (zh) | 2011-08-01 | 2016-08-17 | 德诺弗科学公司 | 细胞捕获系统和使用方法 |
US10466160B2 (en) | 2011-08-01 | 2019-11-05 | Celsee Diagnostics, Inc. | System and method for retrieving and analyzing particles |
DE102011109332A1 (de) | 2011-08-03 | 2013-02-07 | Eppendorf Ag | Laborvorrichtung und Verfahren zur Behandlung von Laborproben |
ITTO20110990A1 (it) | 2011-10-28 | 2013-04-29 | Silicon Biosystems Spa | Metodo ed apparato per l'analisi ottica di particelle a basse temperature |
US9075039B2 (en) * | 2011-11-08 | 2015-07-07 | Becton, Dickinson And Company | Container and cap for a biological specimen |
EP2594632A1 (en) * | 2011-11-18 | 2013-05-22 | Miltenyi Biotec GmbH | Method and device for cell modification |
DK2597153T3 (en) | 2011-11-25 | 2016-12-05 | Miltenyi Biotec Gmbh | Method for cell separation |
EP2795289B1 (en) * | 2011-12-21 | 2022-08-31 | Becton Dickinson and Company | Flow cytometric systems for sterile separation of magnetically labeled sample components |
ITBO20110766A1 (it) | 2011-12-28 | 2013-06-29 | Silicon Biosystems Spa | Dispositivi, apparato, kit e metodo per il trattamento di un campione biologico |
SG11201404991YA (en) | 2012-02-23 | 2014-09-26 | Stage Cell Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
CH706420A1 (fr) * | 2012-04-19 | 2013-10-31 | Valerie Soulie | Procédé d'inactivation virale d'un fluide biologique, dispositif et récipient pour la mise en œuvre d'un tel procédé. |
EP2848935A4 (en) * | 2012-05-10 | 2015-12-09 | Konica Minolta Inc | PROCESS FOR REMOVING RED BLOOD BODIES AND CENTRIFUGAL TUBES FOR BLOOD TREATMENT |
EP2664383A1 (en) | 2012-05-15 | 2013-11-20 | Miltenyi Biotec GmbH | Centrifugation chamber with deflector shields |
EP2711418B1 (en) | 2012-09-25 | 2017-08-23 | Miltenyi Biotec GmbH | Method for polyclonal stimulation of T cells by flexible nanomatrices |
US9265925B2 (en) * | 2012-10-16 | 2016-02-23 | Acist Medical Systems, Inc. | Controlling flow in a medical injection system |
US9434940B2 (en) | 2012-12-19 | 2016-09-06 | Dna Electronics, Inc. | Methods for universal target capture |
US9995742B2 (en) | 2012-12-19 | 2018-06-12 | Dnae Group Holdings Limited | Sample entry |
US10000557B2 (en) | 2012-12-19 | 2018-06-19 | Dnae Group Holdings Limited | Methods for raising antibodies |
US9551704B2 (en) | 2012-12-19 | 2017-01-24 | Dna Electronics, Inc. | Target detection |
US9599610B2 (en) | 2012-12-19 | 2017-03-21 | Dnae Group Holdings Limited | Target capture system |
US9752181B2 (en) * | 2013-01-26 | 2017-09-05 | Denovo Sciences, Inc. | System and method for capturing and analyzing cells |
EP2956541B1 (en) * | 2013-02-15 | 2018-12-26 | Douglas T. Gjerde | Devices and methods for purification of biological cells |
US9707562B2 (en) | 2013-03-13 | 2017-07-18 | Denovo Sciences, Inc. | System for capturing and analyzing cells |
US9856535B2 (en) | 2013-05-31 | 2018-01-02 | Denovo Sciences, Inc. | System for isolating cells |
US10391490B2 (en) | 2013-05-31 | 2019-08-27 | Celsee Diagnostics, Inc. | System and method for isolating and analyzing cells |
US9884326B2 (en) * | 2013-06-28 | 2018-02-06 | National Institute Of Advanced Industrial Science And Technology | Matrix for magnetic separator and magnetic separator |
EP2821144A1 (en) | 2013-07-02 | 2015-01-07 | Miltenyi Biotec GmbH | Centrifugation chamber with gas-permeable membrane for cell cultivation |
ES2755741T3 (es) * | 2013-07-02 | 2020-04-23 | Miltenyi Biotec Bv & Co Kg | Cámara de centrifugación con capas de membranas permeables a los gases para cultivo celular |
US20150017714A1 (en) * | 2013-07-02 | 2015-01-15 | Miltenyi Biotec Gmbh | Centrifugation chamber with gas permeable membrane layers for cell cultivation |
CN103333799A (zh) * | 2013-07-09 | 2013-10-02 | 广州一代医药科技有限公司 | 一种纳米铁结合蛋白吸附的细胞磁性分选装置 |
ES2612918T3 (es) | 2013-07-10 | 2017-05-19 | Miltenyi Biotec Gmbh | Método para inducir la proliferación de células asesinas naturales por nanomatrices móviles |
WO2015160320A1 (en) * | 2014-04-15 | 2015-10-22 | Promedart Biyoteknoloji Ve Ozel Saglik Hizmetleri Sanayi Ticaret Limited Sirketi | A separation system |
PT3132247T (pt) | 2014-04-16 | 2021-11-03 | Juno Therapeutics Gmbh | Métodos, kits e aparelho para ampliar uma população de células |
CN106459917B (zh) | 2014-04-23 | 2021-03-09 | 朱诺治疗学股份有限公司 | 分离、培养和遗传工程改造用于过继治疗的免疫细胞群的方法 |
US9493789B2 (en) | 2014-04-24 | 2016-11-15 | Miltenyi Biotec Gmbh | Automated generation of genetically modified stem cells |
EP3134512B1 (en) | 2014-04-24 | 2019-01-02 | Miltenyi Biotec GmbH | Method for automated generation of genetically modified t cells |
KR102379845B1 (ko) | 2014-05-30 | 2022-03-28 | 피네쎄 솔루션스, 아이엔씨 | 바이오 프로세스 컨테이너용 무균 접속기 |
US9346578B2 (en) * | 2014-05-30 | 2016-05-24 | Finesse Solutions, Inc. | Aseptic connectors for bio-processing containers |
EP3169773B1 (en) | 2014-07-15 | 2023-07-12 | Juno Therapeutics, Inc. | Engineered cells for adoptive cell therapy |
CA2958757C (en) | 2014-08-19 | 2021-04-27 | Miltenyi Biotec Gmbh | Chimeric antigen receptor specific for ssea4 antigen |
TWI751102B (zh) | 2014-08-28 | 2022-01-01 | 美商奇諾治療有限公司 | 對cd19具專一性之抗體及嵌合抗原受體 |
CN117427091A (zh) | 2014-10-20 | 2024-01-23 | 朱诺治疗学股份有限公司 | 用于过继细胞治疗中的给药的组合物和方法 |
BR112017009220B1 (pt) | 2014-11-05 | 2022-04-12 | Juno Therapeutics Inc | Método de transdução de células |
US11266739B2 (en) | 2014-12-03 | 2022-03-08 | Juno Therapeutics, Inc. | Methods and compositions for adoptive cell therapy |
US10421081B2 (en) | 2014-12-19 | 2019-09-24 | National Technology & Engineering Solutions Of Sandia, Llc | Centrifuge with vector-seeking linkage |
CN107106744B (zh) * | 2014-12-19 | 2020-12-01 | 生物安全股份有限公司 | 生物流体的顺序处理 |
US9926524B2 (en) | 2014-12-22 | 2018-03-27 | Saint-Gobain Performance Plastics Corporation | Gas permeable material |
US10655097B2 (en) | 2014-12-22 | 2020-05-19 | Saint-Gobain Performance Plastics Corporation | T-cell culture double bag assembly |
US10280390B2 (en) | 2014-12-22 | 2019-05-07 | Saint-Gobain Performance Plastics Corporation | System for culture of cells in a controlled environment |
MA41346A (fr) | 2015-01-12 | 2017-11-21 | Juno Therapeutics Inc | Eléments régulateurs post-transcriptionnels d'hépatite modifiée |
WO2016115559A1 (en) | 2015-01-16 | 2016-07-21 | Juno Therapeutics, Inc. | Antibodies and chimeric antigen receptors specific for ror1 |
EP3247808B1 (en) | 2015-01-21 | 2021-05-05 | Fred Hutchinson Cancer Research Center | Point-of-care and/or portable platform for gene therapy |
EP3061809B1 (en) | 2015-02-27 | 2019-01-30 | Miltenyi Biotec GmbH | Method for generation of a cell composition of mesencephalic dopaminergic progenitor cells |
WO2016166568A1 (en) | 2015-04-16 | 2016-10-20 | Juno Therapeutics Gmbh | Methods, kits and apparatus for expanding a population of cells |
CN107530486B (zh) | 2015-05-08 | 2020-12-11 | 生物磁溶液有限公司 | 免疫磁性细胞分离的装置和方法 |
EP3091032A1 (en) | 2015-05-08 | 2016-11-09 | Miltenyi Biotec GmbH | Humanized antibody or fragment thereof specific for cd3 |
JP6457338B2 (ja) * | 2015-05-28 | 2019-01-23 | 株式会社日立製作所 | 液体還流容器、細胞濃縮装置及び細胞濃縮システム |
EP3303586A1 (en) | 2015-05-29 | 2018-04-11 | Juno Therapeutics, Inc. | Composition and methods for regulating inhibitory interactions in genetically engineered cells |
GB2598499B (en) * | 2015-06-05 | 2022-05-25 | Novartis Ag | Flow-through paramagnetic particle-based cell separation and paramagnetic particle removal |
GB201511129D0 (en) * | 2015-06-24 | 2015-08-05 | Linea Ab Q | Method of determining antimicrobial susceptibility of a microorganism |
MA42895A (fr) | 2015-07-15 | 2018-05-23 | Juno Therapeutics Inc | Cellules modifiées pour thérapie cellulaire adoptive |
EP3138905A1 (en) | 2015-09-04 | 2017-03-08 | Miltenyi Biotec GmbH | Method for natural killer cell expansion |
ES2687422T3 (es) | 2015-09-07 | 2018-10-25 | Miltenyi Biotec Gmbh | Cartucho desechable para electroporación |
US10077422B2 (en) * | 2015-09-28 | 2018-09-18 | The University Of Toledo | Microalgae harvesting using stimuli-sensitive hydrogels |
EP3365453A2 (en) | 2015-10-22 | 2018-08-29 | Juno Therapeutics GmbH | Methods, kits, agents and apparatuses for transduction |
MA45488A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
EP3371295A1 (en) * | 2015-11-04 | 2018-09-12 | Northeastern University | Systems for producing cellular immunotherapeutics and methods of use thereof |
US11020429B2 (en) | 2015-11-05 | 2021-06-01 | Juno Therapeutics, Inc. | Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy |
MA44314A (fr) | 2015-11-05 | 2018-09-12 | Juno Therapeutics Inc | Récepteurs chimériques contenant des domaines induisant traf, et compositions et méthodes associées |
CA3007262A1 (en) | 2015-12-03 | 2017-06-08 | Lucas James Thompson | Modified chimeric receptors and related compositions and methods |
ES2928167T3 (es) | 2015-12-03 | 2022-11-15 | Juno Therapeutics Inc | Composiciones y métodos para reducir las respuestas inmunitarias contra receptores de antígenos quiméricos |
EP3384294B1 (en) | 2015-12-04 | 2021-10-13 | Juno Therapeutics, Inc. | Methods and compositions related to toxicity associated with cell therapy |
SG11201804957VA (en) | 2015-12-16 | 2018-07-30 | Gritstone Oncology Inc | Neoantigen identification, manufacture, and use |
EP3184548A1 (en) | 2015-12-23 | 2017-06-28 | Miltenyi Biotec GmbH | Chimeric antigen receptor with cytokine receptor activating or blocking domain |
WO2017153974A1 (en) * | 2016-03-07 | 2017-09-14 | Caladrius Biosciences, Inc. | A closed system for labelling and selecting live cells |
US20190355459A1 (en) | 2016-03-16 | 2019-11-21 | Juno Therapeutics, Inc. | Methods for adaptive design of a treatment regimen and related treatments |
WO2017161208A1 (en) | 2016-03-16 | 2017-09-21 | Juno Therapeutics, Inc. | Methods for determining dosing of a therapeutic agent and related treatments |
SG11201808014SA (en) | 2016-03-18 | 2018-10-30 | Qt Holdings Corp | Compositions, devices, and methods for cell separation |
MA44486A (fr) | 2016-03-22 | 2019-01-30 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Procédés d'intervention précoce pour prévenir ou atténuer la toxicité |
CN109196331A (zh) | 2016-04-15 | 2019-01-11 | 贝克顿·迪金森公司 | 封闭式小滴分选器以及其使用方法 |
KR20240096679A (ko) | 2016-04-20 | 2024-06-26 | 센트로 데 인베스띠가씨오네스 에너제티까스 메디오암비엔딸레스 와이 테크놀로지까스, 오.에이., 엠.피. | Pklr의 유전자 발현 증강을 위한 조성물 및 방법 |
US10449283B2 (en) | 2016-04-29 | 2019-10-22 | Fenwal, Inc. | System and method for selecting and culturing cells |
CN108883414B (zh) | 2016-04-29 | 2021-06-01 | 建奥迪斯有限公司 | 用于分子回收的方法和组件 |
US10251990B2 (en) | 2016-04-29 | 2019-04-09 | Fenwal, Inc. | System and method for processing, incubating, and/or selecting biological cells |
EP3241905A1 (en) | 2016-05-06 | 2017-11-08 | Miltenyi Biotec GmbH | Method for introducing nucleic acids into a cell |
CA3026318C (en) | 2016-06-01 | 2023-04-04 | Miltenyi Biotec Gmbh | Process for generation, identification and isolation of human pluripotent stem cell-derived cardiomyocytes and cardiomyocyte subpopulations |
CN109562127A (zh) | 2016-06-03 | 2019-04-02 | 纪念斯隆-凯特琳癌症中心 | 作为早期治疗选择的过继细胞疗法 |
MA45341A (fr) | 2016-06-06 | 2019-04-10 | Hutchinson Fred Cancer Res | Procédés de traitement de malignités de lymphocytes b au moyen d'une thérapie cellulaire adoptive |
MA45491A (fr) | 2016-06-27 | 2019-05-01 | Juno Therapeutics Inc | Épitopes à restriction cmh-e, molécules de liaison et procédés et utilisations associés |
EP3475446A1 (en) | 2016-06-27 | 2019-05-01 | Juno Therapeutics, Inc. | Method of identifying peptide epitopes, molecules that bind such epitopes and related uses |
JP6821785B2 (ja) * | 2016-07-22 | 2021-01-27 | アルファ ワッサーマン インコーポレイテッドAlfa Wassermann,Inc. | 超遠心分離機用の流体取扱システム及び方法 |
DE102016114043B3 (de) | 2016-07-29 | 2017-08-10 | Technische Universität Dresden | Vorrichtung zur Isolierung von Stammzellen aus fötalen Geweben |
CA3031994A1 (en) | 2016-07-29 | 2018-02-01 | Juno Therapeutics, Inc. | Methods for assessing the presence or absence of replication competent virus |
MX2019001184A (es) | 2016-07-29 | 2019-09-26 | Juno Therapeutics Inc | Anticuerpos anti-idiotípicos y métodos relacionados. |
MX2019001185A (es) | 2016-07-29 | 2019-10-21 | Juno Therapeutics Inc | Polipeptidos inmunomoduladores y composiciones y metodos relacionados. |
US11561219B2 (en) | 2016-08-26 | 2023-01-24 | Juno Therapeutics, Inc. | Methods of enumerating particles present in a cell composition |
CN109843317A (zh) * | 2016-08-29 | 2019-06-04 | 哈肯萨克大学医学中心 | 通过人中含有血小板样细胞的血液的富含血小板级分的干性用于使成体细胞重编程的组合物和方法 |
RU2755725C2 (ru) | 2016-09-12 | 2021-09-20 | Джуно Терапьютикс, Инк. | Сборочные узлы перфузионных биореакторных мешков |
AU2017338827B2 (en) | 2016-10-03 | 2023-08-31 | Juno Therapeutics, Inc. | HPV-specific binding molecules |
US12024702B2 (en) * | 2016-10-10 | 2024-07-02 | Biomerieux | Method and device for preparing samples |
AU2017343780B2 (en) | 2016-10-13 | 2023-08-31 | Juno Therapeutics, Inc. | Immunotherapy methods and compositions involving tryptophan metabolic pathway modulators |
US10617720B2 (en) | 2016-10-20 | 2020-04-14 | Miltenyi Biotech, GmbH | Chimeric antigen receptor specific for tumor cells |
EP3315511A1 (en) | 2016-10-29 | 2018-05-02 | Miltenyi Biotec GmbH | Adapter chimeric antigen receptor expressing cells for targeting of multiple antigens |
WO2018085731A2 (en) | 2016-11-03 | 2018-05-11 | Juno Therapeutics, Inc. | Combination therapy of a t cell therapy and a btk inhibitor |
CA3040914A1 (en) | 2016-11-03 | 2018-05-24 | Juno Therapeutics, Inc. | Combination therapy of a cell based therapy and a microglia inhibitor |
KR102624417B1 (ko) * | 2016-11-23 | 2024-01-11 | 일루미나, 인코포레이티드 | 플로우 셀 어셈블리 고정 시스템 및 방법 |
US10718786B2 (en) | 2016-11-23 | 2020-07-21 | Illumina, Inc. | Flow cell assembly securement system and method |
WO2018102612A1 (en) | 2016-12-02 | 2018-06-07 | Juno Therapeutics, Inc. | Engineered b cells and related compositions and methods |
KR20190104528A (ko) | 2016-12-03 | 2019-09-10 | 주노 쎄러퓨티크스 인코퍼레이티드 | Car-t 세포들 투여를 결정하는 방법 |
CN110248678A (zh) | 2016-12-03 | 2019-09-17 | 朱诺治疗学股份有限公司 | 调节car-t细胞的方法 |
MA46995A (fr) | 2016-12-03 | 2019-10-09 | Acerta Pharma Bv | Méthodes et compositions pour l'utilisation de lymphocytes t thérapeutiques en association avec des inhibiteurs de kinase |
MX2019006438A (es) | 2016-12-05 | 2019-11-28 | Juno Therapeutics Inc | Produccion de celulas modificadas para terapia de celulas adoptivas. |
EP3336107A1 (en) | 2016-12-15 | 2018-06-20 | Miltenyi Biotec GmbH | Immune cells expressing an antigen binding receptor and a chimeric costimulatory receptor |
US10274495B2 (en) | 2016-12-21 | 2019-04-30 | Fenwal, Inc. | System and method for separating cells incorporating magnetic separation |
US20180179490A1 (en) | 2016-12-27 | 2018-06-28 | Miltenyi Biotec Gmbh | CELL COMPOSITION DEPLETED FROM TCRab and CD45RA POSITIVE CELLS |
CN110382014A (zh) * | 2017-01-08 | 2019-10-25 | 赛斯卡医疗有限公司 | 用于生物加工细胞样品的装置和方法 |
AU2018207305A1 (en) | 2017-01-10 | 2019-07-25 | Juno Therapeutics, Inc. | Epigenetic analysis of cell therapy and related methods |
CN110418802A (zh) | 2017-01-20 | 2019-11-05 | 朱诺治疗学有限公司 | 细胞表面缀合物及相关的细胞组合物和方法 |
WO2018151836A1 (en) | 2017-02-17 | 2018-08-23 | Fred Hutchinson Cancer Research Center | Combination therapies for treatment of bcma-related cancers and autoimmune disorders |
US20200191774A1 (en) | 2017-02-27 | 2020-06-18 | Juno Therapeutics, Inc. | Compositions, articles of manufacture and methods related to dosing in cell therapy |
BR112019019005A2 (pt) | 2017-03-14 | 2020-04-14 | Sara Elizabeth Church | métodos para armazenagem criogênica |
CA3056542A1 (en) | 2017-03-15 | 2018-09-20 | Oxford Biomedica (Uk) Limited | Method |
WO2018187791A1 (en) | 2017-04-07 | 2018-10-11 | Juno Therapeutics, Inc | Engineered cells expressing prostate-specific membrane antigen (psma) or a modified form thereof and related methods |
JP7355650B2 (ja) | 2017-04-14 | 2023-10-03 | ジュノー セラピューティクス インコーポレイテッド | 細胞表面グリコシル化を評価するための方法 |
WO2018197949A1 (en) | 2017-04-27 | 2018-11-01 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
PT3618842T (pt) | 2017-05-01 | 2024-01-12 | Juno Therapeutics Inc | Combinação de uma terapia celular e de um composto imunomodulador |
EP3630132A1 (en) | 2017-06-02 | 2020-04-08 | Juno Therapeutics, Inc. | Articles of manufacture and methods for treatment using adoptive cell therapy |
EP3631468A1 (en) | 2017-06-02 | 2020-04-08 | Juno Therapeutics, Inc. | Articles of manufacture and methods related to toxicity associated with cell therapy |
EP3638774B1 (en) | 2017-06-14 | 2024-08-07 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Methods for purifying endoderm and pancreatic endoderm cells derived from human embryonic stem cells |
WO2019006427A1 (en) | 2017-06-29 | 2019-01-03 | Juno Therapeutics, Inc. | WALL MODEL FOR ASSESSING TOXICITIES ASSOCIATED WITH IMMUNOTHERAPIES |
AU2018310452A1 (en) | 2017-07-29 | 2020-02-13 | Juno Therapeutics, Inc. | Reagents for expanding cells expressing recombinant receptors |
NZ761124A (en) | 2017-08-09 | 2024-07-05 | Juno Therapeutics Inc | Methods and compositions for preparing genetically engineered cells |
AU2018313950A1 (en) | 2017-08-09 | 2020-02-13 | Juno Therapeutics, Inc. | Methods for producing genetically engineered cell compositions and related compositions |
AU2018323449B2 (en) | 2017-08-29 | 2020-09-03 | Bio-Rad Laboratories, Inc. | System and method for isolating and analyzing cells |
US20210071258A1 (en) | 2017-09-01 | 2021-03-11 | Juno Therapeutics, Inc. | Gene expression and assessment of risk of developing toxicity following cell therapy |
KR20230092033A (ko) | 2017-09-01 | 2023-06-23 | 론차 콜로그네 게엠베하 | 엔드-투-엔드 세포 요법의 자동화 |
JP7393328B2 (ja) | 2017-09-01 | 2023-12-06 | ジーピービー・サイエンティフィック・インコーポレイテッド | マイクロ流体を使用した治療的に活性な細胞を調製する方法 |
EP3679370A1 (en) | 2017-09-07 | 2020-07-15 | Juno Therapeutics, Inc. | Methods of identifying cellular attributes related to outcomes associated with cell therapy |
SG11202002156SA (en) * | 2017-09-21 | 2020-04-29 | Repligen Corp | Methods and systems for removing pressure and air from chromatography columns |
JP2020537515A (ja) | 2017-10-03 | 2020-12-24 | ジュノー セラピューティクス インコーポレイテッド | Hpv特異的結合分子 |
JP7227237B2 (ja) | 2017-10-10 | 2023-02-21 | グリットストーン バイオ インコーポレイテッド | ホットスポットを利用した新生抗原の特定 |
BR112020007444A2 (pt) | 2017-10-16 | 2020-10-20 | Centro de Investigaciones Energeticas, Medioambientales Y Tecnologicas, O.A., M.P. | vetores lentivirais para a liberação de pklr para tratar deficiência de piruvato quinase |
US12031975B2 (en) | 2017-11-01 | 2024-07-09 | Juno Therapeutics, Inc. | Methods of assessing or monitoring a response to a cell therapy |
WO2019089969A2 (en) | 2017-11-01 | 2019-05-09 | Juno Therapeutics, Inc. | Antibodies and chimeric antigen receptors specific for b-cell maturation antigen |
AU2018360801A1 (en) | 2017-11-01 | 2020-05-14 | Celgene Corporation | Process for producing a T cell composition |
WO2019089848A1 (en) | 2017-11-01 | 2019-05-09 | Juno Therapeutics, Inc. | Methods associated with tumor burden for assessing response to a cell therapy |
KR20200099132A (ko) | 2017-11-01 | 2020-08-21 | 주노 쎄러퓨티크스 인코퍼레이티드 | 조작된 세포의 치료적 조성물을 생성하기 위한 프로세스 |
CN111902159A (zh) | 2017-11-01 | 2020-11-06 | 朱诺治疗学股份有限公司 | 对b细胞成熟抗原(bcma)具有特异性的嵌合抗原受体 |
BR112020008812A2 (pt) | 2017-11-06 | 2020-10-27 | Juno Therapeutics Inc | combinação de terapia celular e um inibidor de gama secretase |
JP2021502094A (ja) | 2017-11-10 | 2021-01-28 | ジュノー セラピューティクス インコーポレイテッド | 閉鎖系極低温容器 |
CN111630602A (zh) | 2017-11-22 | 2020-09-04 | 磨石肿瘤生物技术公司 | 减少新抗原的接合表位呈递 |
CN111433350B (zh) * | 2017-11-30 | 2023-11-14 | 烟台澳斯邦生物工程有限公司 | 从生物样品分离颗粒的方法、系统和过滤单元 |
CN111989106A (zh) | 2017-12-01 | 2020-11-24 | 朱诺治疗学股份有限公司 | 基因工程化细胞的给药和调节方法 |
EP3717622A1 (en) * | 2017-12-01 | 2020-10-07 | Global Life Sciences Solutions USA LLC | Methods for cell enrichment and isolation |
GB201720405D0 (en) | 2017-12-07 | 2018-01-24 | Biosafe Sa | A bioprocessing system |
BR112020011215A2 (pt) | 2017-12-08 | 2020-11-17 | Juno Therapeutics Inc | processo para a produção de uma composição de células t modificadas |
US20210128616A1 (en) | 2017-12-08 | 2021-05-06 | Juno Therapeutics, Inc. | Phenotypic markers for cell therapy and related methods |
MX2020005907A (es) | 2017-12-08 | 2020-10-19 | Juno Therapeutics Inc | Formulacion de medio libre de suero para cultivar celulas y metodos de uso de la misma. |
EP3724225A1 (en) | 2017-12-15 | 2020-10-21 | Juno Therapeutics, Inc. | Anti-cct5 binding molecules and methods of use thereof |
US11957715B2 (en) | 2017-12-20 | 2024-04-16 | Miltenyi Biotec B.V. & Co. KG | Method for NK cell transduction |
EP3735425A1 (en) | 2018-01-04 | 2020-11-11 | Miltenyi Biotec B.V. & Co. KG | Chimeric antigen receptor specific for bdca2 antigen |
JP2021511041A (ja) | 2018-01-19 | 2021-05-06 | ミルテニイ バイオテック ベー.ファオ. ウント コー.カーゲー | キメラ抗原受容体を発現する制御性t細胞 |
JP7383620B2 (ja) | 2018-01-31 | 2023-11-20 | セルジーン コーポレイション | 養子細胞療法およびチェックポイント阻害剤を使用する併用療法 |
EP3746569A1 (en) | 2018-01-31 | 2020-12-09 | Juno Therapeutics, Inc. | Methods and reagents for assessing the presence or absence of replication competent virus |
BR112020015512A2 (pt) | 2018-02-01 | 2021-01-26 | Nkmax Co., Ltd. | método de produção de células exterminadoras naturais e composição para tratamento de câncer |
US11932842B2 (en) | 2018-02-09 | 2024-03-19 | Global Life Sciences Solutions Usa Llc | Bioprocessing apparatus |
US11920119B2 (en) | 2018-02-09 | 2024-03-05 | Global Life Sciences Solutions Usa Llc | Systems and methods for bioprocessing |
US12077743B2 (en) | 2018-02-09 | 2024-09-03 | Global Life Sciences Solutions Usa Llc | Apparatus for fluid line management in a bioprocessing system |
WO2019169194A1 (en) | 2018-02-28 | 2019-09-06 | Juno Therapeutics, Inc. | Methods for detecting particles present in a cell composition |
WO2019170845A1 (en) | 2018-03-09 | 2019-09-12 | Ospedale San Raffaele S.R.L. | Il-1 antagonist and toxicity induced by cell therapy |
CN108680430B (zh) * | 2018-03-15 | 2020-11-24 | 水利部交通运输部国家能源局南京水利科学研究院 | 一种尾矿料离心模型固结渗流控制系统及试验方法 |
EP3775237A1 (en) | 2018-04-05 | 2021-02-17 | Juno Therapeutics, Inc. | T cells expressing a recombinant receptor, related polynucleotides and methods |
BR112020020245A2 (pt) | 2018-04-05 | 2021-04-06 | Editas Medicine, Inc. | Métodos de produzir células expressando um receptor recombinante e composições relacionadas |
KR20210019993A (ko) | 2018-04-05 | 2021-02-23 | 주노 쎄러퓨티크스 인코퍼레이티드 | Τ 세포 수용체 및 이를 발현하는 조작된 세포 |
JP7366931B2 (ja) | 2018-04-27 | 2023-10-23 | ベクトン・ディキンソン・アンド・カンパニー | 制御されたエアロゾル含有量を有する密閉された液滴ソータを有するフローサイトメータおよびそれを使用する方法 |
JP7374124B2 (ja) | 2018-04-27 | 2023-11-06 | ベクトン・ディキンソン・アンド・カンパニー | フローサイトメトリで選別された試料のための収集システムおよびそれを使用する方法 |
KR20210044736A (ko) | 2018-05-03 | 2021-04-23 | 주노 쎄러퓨티크스 인코퍼레이티드 | 키메라 항원 수용체(car) t세포 요법과 키나제 억제제의 조합요법 |
US11413378B2 (en) | 2018-05-08 | 2022-08-16 | Biomagnetic Solutions Llc | Rigid chamber for cell separation from a flexible disposable bag |
WO2019217964A1 (en) | 2018-05-11 | 2019-11-14 | Lupagen, Inc. | Systems and methods for closed loop, real-time modifications of patient cells |
WO2019234033A1 (en) | 2018-06-06 | 2019-12-12 | Pierson Yann | Apparatus and process for the automated manufacturing of genetically engineered cells from biological fluids |
SG11202012299SA (en) | 2018-06-13 | 2021-01-28 | Akron Biotechnology Llc | Method to prepare therapeutically active aldesleukin highly stable in liquid pharmaceutical compositions |
WO2020020569A1 (en) * | 2018-07-27 | 2020-01-30 | Univercells S.A. | System and method for the production of biomolecules |
JP7538109B2 (ja) | 2018-08-09 | 2024-08-21 | ジュノー セラピューティクス インコーポレイテッド | 組み込まれた核酸を評価するための方法 |
CA3108657A1 (en) | 2018-08-09 | 2020-02-13 | Juno Therapeutics, Inc. | Processes for generating engineered cells and compositions thereof |
US10988726B2 (en) | 2018-08-19 | 2021-04-27 | Cytera Cellworks Limited | Systems and methods for automated cell culturing |
CA3110905A1 (en) | 2018-08-31 | 2020-03-05 | Invectys SA | Chimeric antigen receptors against multiple hla-g isoforms |
BR112021004261A2 (pt) | 2018-09-11 | 2021-05-25 | Juno Therapeutics Inc | métodos para análise por espectrometria de massas de composições de células geneticamente modificadas |
CN112805548A (zh) | 2018-10-30 | 2021-05-14 | 贝克顿·迪金森公司 | 具有对准窗口的颗粒分选模块、系统及其使用方法 |
JP2022506598A (ja) | 2018-11-01 | 2022-01-17 | ジュノー セラピューティクス インコーポレイテッド | Gタンパク質共役受容体クラスcグループ5メンバーd(gprc5d)に特異的なキメラ抗原受容体 |
MA54078A (fr) | 2018-11-01 | 2021-09-15 | Juno Therapeutics Inc | Méthodes pour le traitement au moyen de récepteurs antigéniques chimériques spécifiques de l'antigene de maturation des lymphocytes b |
WO2020097132A1 (en) | 2018-11-06 | 2020-05-14 | Juno Therapeutics, Inc. | Process for producing genetically engineered t cells |
AU2019377854A1 (en) | 2018-11-08 | 2021-05-27 | Juno Therapeutics, Inc. | Methods and combinations for treatment and T cell modulation |
WO2020102770A1 (en) | 2018-11-16 | 2020-05-22 | Juno Therapeutics, Inc. | Methods of dosing engineered t cells for the treatment of b cell malignancies |
SG11202105502RA (en) | 2018-11-30 | 2021-06-29 | Juno Therapeutics Inc | Methods for treatment using adoptive cell therapy |
PT3886894T (pt) | 2018-11-30 | 2024-05-02 | Juno Therapeutics Inc | Métodos para dosagem e tratamento de malignidades de células b em terapia celular adotiva |
CN113366099A (zh) | 2018-12-21 | 2021-09-07 | 奥克泰生物科技股份有限公司 | 用于模块化生物生产单元的转盘 |
CA3123449A1 (en) | 2018-12-21 | 2020-06-25 | Lonza Walkersville, Inc. | Automated production of viral vectors |
KR20210110322A (ko) | 2018-12-28 | 2021-09-07 | 옥테인 바이오테크 인코포레이티드 | 제어된 환경 존을 포함하는 세포 배양 및 조직 공학 시스템 |
JP2022518925A (ja) | 2019-01-29 | 2022-03-17 | ジュノー セラピューティクス インコーポレイテッド | 受容体チロシンキナーゼ様オーファン受容体1(ror1)に特異的な抗体およびキメラ抗原受容体 |
WO2020163454A1 (en) | 2019-02-08 | 2020-08-13 | Lonza Walkersville, Inc. | Cell concentration methods and devices for use in automated bioreactors |
DE102019106651A1 (de) | 2019-03-15 | 2020-09-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Behandlungsvorrichtung und -verfahren zur extrakorporalen, Immuntoleranz-steigernden Blutbehandlung |
US10633693B1 (en) | 2019-04-16 | 2020-04-28 | Celsee Diagnostics, Inc. | System and method for leakage control in a particle capture system |
AU2020265741A1 (en) | 2019-05-01 | 2021-11-25 | Editas Medicine, Inc. | Cells expressing a recombinant receptor from a modified TGFBR2 Locus, related polynucleotides and methods |
KR20220016474A (ko) | 2019-05-01 | 2022-02-09 | 주노 쎄러퓨티크스 인코퍼레이티드 | 변형된 cd247 유전자 자리로부터 키메라 수용체를 발현하는 세포, 관련 폴리뉴클레오타이드 및 방법 |
US11273439B2 (en) | 2019-05-07 | 2022-03-15 | Bio-Rad Laboratories, Inc. | System and method for target material retrieval from microwells |
CN114072490A (zh) | 2019-05-07 | 2022-02-18 | 伯乐实验室有限公司 | 用于自动化的单细胞加工的系统和方法 |
CN113966394A (zh) | 2019-05-28 | 2022-01-21 | 美天施生物科技有限两合公司 | 产生遗传修饰的t细胞的方法 |
WO2020252218A1 (en) | 2019-06-12 | 2020-12-17 | Juno Therapeutics, Inc. | Combination therapy of a cell-mediated cytotoxic therapy and an inhibitor of a prosurvival bcl2 family protein |
SG11202112898WA (en) | 2019-06-14 | 2021-12-30 | Bio Rad Laboratories | System and method for automated single cell processing and analyses |
US11604195B2 (en) | 2019-08-22 | 2023-03-14 | Michael IANNOTTI | High throughput analysis and sorting, and sampling interface and assembly for high throughput analysis and sorting |
CN114555112A (zh) | 2019-08-22 | 2022-05-27 | 朱诺治疗学股份有限公司 | T细胞疗法和zeste增强子同源物2(ezh2)抑制剂的组合疗法及相关方法 |
WO2021041994A2 (en) | 2019-08-30 | 2021-03-04 | Juno Therapeutics, Inc. | Machine learning methods for classifying cells |
WO2021047804A1 (en) | 2019-09-11 | 2021-03-18 | Miltenyi Biotec B.V. & Co. KG | In vitro method for transduction of t cells in the presence of malignant cells |
EP3792346B1 (en) | 2019-09-13 | 2023-07-26 | Miltenyi Biotec B.V. & Co. KG | Method for the generation of a cell composition of ventral midbrain dopaminergic progenitor cells |
CN115087868A (zh) | 2019-11-05 | 2022-09-20 | 朱诺治疗学股份有限公司 | 确定治疗性t细胞组合物的属性的方法 |
BR112022007548A2 (pt) | 2019-11-07 | 2022-07-12 | Juno Therapeutics Inc | Combinação de uma terapia de célula t e (s)-3-[4-(4-morfolin-4-ilmetil-benzilóxi)-1-oxo-1,3-di-hidro-isoindol-2-il]-piperidina-2,6-diona |
CN115916817A (zh) | 2019-12-06 | 2023-04-04 | 朱诺治疗学股份有限公司 | 针对bcma靶向结合结构域的抗独特型抗体及相关组合物和方法 |
US11000780B1 (en) * | 2019-12-06 | 2021-05-11 | AnuCell Biosystems Limited | Torus reactor for a combined cell isolator and bioreactor |
AU2020395318A1 (en) | 2019-12-06 | 2022-06-09 | Juno Therapeutics, Inc. | Methods related to toxicity and response associated with cell therapy for treating B cell malignancies |
EP4069742A1 (en) | 2019-12-06 | 2022-10-12 | Juno Therapeutics, Inc. | Anti-idiotypic antibodies to gprc5d-targeted binding domains and related compositions and methods |
AU2021209940A1 (en) | 2020-01-24 | 2022-08-04 | Juno Therapeutics, Inc. | Methods for dosing and treatment of follicular lymphoma and marginal zone lymphoma in adoptive cell therapy |
KR20220146480A (ko) | 2020-01-28 | 2022-11-01 | 주노 쎄러퓨티크스 인코퍼레이티드 | T 세포 형질도입 방법 |
US20210260600A1 (en) * | 2020-02-01 | 2021-08-26 | Sunil Mehta | Automated device and method to purify biomaterials from a mixture by using magnetic particles and disposable product-contact materials |
US20230087953A1 (en) | 2020-02-12 | 2023-03-23 | Juno Therapeutics, Inc. | Bcma-directed chimeric antigen receptor t cell compositions and methods and uses thereof |
WO2021163391A1 (en) | 2020-02-12 | 2021-08-19 | Juno Therapeutics, Inc. | Cd19-directed chimeric antigen receptor t cell compositions and methods and uses thereof |
EP4107247A2 (en) | 2020-03-10 | 2022-12-28 | Cellares Corporation | Systems, devices, and methods for cell processing |
EP4127127A1 (en) * | 2020-03-27 | 2023-02-08 | Broadley-James Corporation | Single-use bioreactor assembly with integrated pump heads |
KR20230009386A (ko) | 2020-04-10 | 2023-01-17 | 주노 쎄러퓨티크스 인코퍼레이티드 | B-세포 성숙 항원을 표적화하는 키메라 항원 수용체로 조작된 세포 요법 관련 방법 및 용도 |
AU2021263765A1 (en) | 2020-04-28 | 2022-12-01 | Juno Therapeutics, Inc. | Combination of BCMA-directed T cell therapy and an immunomodulatory compound |
CN115835873A (zh) | 2020-05-13 | 2023-03-21 | 朱诺治疗学股份有限公司 | 用于产生表达重组受体的供体分批细胞的方法 |
CN115803824A (zh) | 2020-05-13 | 2023-03-14 | 朱诺治疗学股份有限公司 | 鉴定与临床反应相关的特征的方法及其用途 |
WO2021262147A1 (en) * | 2020-06-23 | 2021-12-30 | Qualigen Inc. | Devices and methods for on-line whole blood treatment |
JP2023531531A (ja) | 2020-06-26 | 2023-07-24 | ジュノ セラピューティクス ゲーエムベーハー | 組換え受容体を条件付きで発現する操作されたt細胞、関連ポリヌクレオチド、および方法 |
US20230295570A1 (en) | 2020-07-23 | 2023-09-21 | Ncardia B.V. | Closed manufacturing processes for large scale manufacturing of pluripotent stem cell derived cells |
CN111992339B (zh) * | 2020-07-28 | 2022-02-11 | 刘肖琳 | 离心分离装置、混合液分离及培养方法 |
WO2022029660A1 (en) | 2020-08-05 | 2022-02-10 | Juno Therapeutics, Inc. | Anti-idiotypic antibodies to ror1-targeted binding domains and related compositions and methods |
KR102581230B1 (ko) | 2020-10-16 | 2023-09-21 | 의료법인 성광의료재단 | 항암 관련 유전자 발현이 조절된 자연살해세포 및 이의 용도 |
US20220127558A1 (en) * | 2020-10-23 | 2022-04-28 | Applied Materials, Inc. | Automated closed system for cell therapy manufacturing |
EP4240403A2 (en) | 2020-11-04 | 2023-09-13 | Miltenyi Biotec B.V. & Co. KG | Chimeric antigen receptor comprising an antigen binding domain specific for msln having a specificity for tumor cells |
CN116802203A (zh) | 2020-11-04 | 2023-09-22 | 朱诺治疗学股份有限公司 | 从经修饰的恒定cd3免疫球蛋白超家族链基因座表达嵌合受体的细胞、相关多核苷酸和方法 |
WO2022133030A1 (en) | 2020-12-16 | 2022-06-23 | Juno Therapeutics, Inc. | Combination therapy of a cell therapy and a bcl2 inhibitor |
CA3211006A1 (en) | 2021-02-20 | 2022-08-25 | Kite Pharma, Inc. | Gene markers for sellecting immunotherapies |
WO2022187406A1 (en) | 2021-03-03 | 2022-09-09 | Juno Therapeutics, Inc. | Combination of a t cell therapy and a dgk inhibitor |
JPWO2022196186A1 (zh) * | 2021-03-16 | 2022-09-22 | ||
JP2024511418A (ja) | 2021-03-22 | 2024-03-13 | ジュノー セラピューティクス インコーポレイテッド | 治療用細胞組成物の効力を決定する方法 |
KR20240005700A (ko) | 2021-03-29 | 2024-01-12 | 주노 쎄러퓨티크스 인코퍼레이티드 | 체크포인트 억제제 요법 및 car t 세포 요법의 조합을 사용한 투여 및 치료 방법 |
AU2022252220A1 (en) | 2021-03-29 | 2023-10-12 | Juno Therapeutics, Inc. | Combination of a car t cell therapy and an immunomodulatory compound for treatment of lymphoma |
CN118201618A (zh) | 2021-04-16 | 2024-06-14 | 细胞基因公司 | 与bcma定向t细胞疗法的组合疗法 |
CA3217354A1 (en) | 2021-05-14 | 2022-11-17 | Kite Pharma, Inc. | Chimeric antigen receptor t cell therapy |
EP4413031A1 (en) | 2021-10-06 | 2024-08-14 | Miltenyi Biotec B.V. & Co. KG | Method for targeted gene insertion into immune cells |
WO2023062113A1 (en) | 2021-10-15 | 2023-04-20 | Miltenyi Biotec B.V. & Co. KG | Method for the generation of genetically modified nk cells |
KR20240112994A (ko) | 2021-11-03 | 2024-07-19 | 셀진 코포레이션 | 골수종을 치료하는 데 사용하기 위한 b-세포 성숙 항원에 특이적인 키메라 항원 수용체 |
WO2023081900A1 (en) | 2021-11-08 | 2023-05-11 | Juno Therapeutics, Inc. | Engineered t cells expressing a recombinant t cell receptor (tcr) and related systems and methods |
WO2023147515A1 (en) | 2022-01-28 | 2023-08-03 | Juno Therapeutics, Inc. | Methods of manufacturing cellular compositions |
WO2023150285A1 (en) | 2022-02-04 | 2023-08-10 | Elixirgen Therapeutics, Inc. | Cell therapy protocol systems and methods |
US20230296610A1 (en) | 2022-02-15 | 2023-09-21 | Kite Pharma, Inc. | Predicting adverse events from immunotherapy |
WO2023164440A1 (en) | 2022-02-22 | 2023-08-31 | Juno Therapeutics, Inc. | Proteinase 3 (pr3) chimeric autoantibody receptor t cells and related methods and uses |
WO2023209175A1 (en) | 2022-04-28 | 2023-11-02 | Bio-Recell Ltd. | Method for separating target cells |
WO2023220655A1 (en) | 2022-05-11 | 2023-11-16 | Celgene Corporation | Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy |
WO2023225048A1 (en) * | 2022-05-17 | 2023-11-23 | Synthego Corporation | Systems and methods for engageable platforms and modules for cell processing |
WO2023230548A1 (en) | 2022-05-25 | 2023-11-30 | Celgene Corporation | Method for predicting response to a t cell therapy |
WO2023230581A1 (en) | 2022-05-25 | 2023-11-30 | Celgene Corporation | Methods of manufacturing t cell therapies |
US20230392119A1 (en) | 2022-05-27 | 2023-12-07 | Kite Pharma, Inc. | Compositions and methods for preparing engineered lymphocytes for cell therapy |
WO2023250400A1 (en) | 2022-06-22 | 2023-12-28 | Juno Therapeutics, Inc. | Treatment methods for second line therapy of cd19-targeted car t cells |
DE102022115737B3 (de) | 2022-06-24 | 2023-07-06 | Imstec Gmbh | Vorrichtung und Verfahren zur automatisierten Zellkultivierung |
WO2024006960A1 (en) | 2022-06-29 | 2024-01-04 | Juno Therapeutics, Inc. | Lipid nanoparticles for delivery of nucleic acids |
WO2024031091A2 (en) | 2022-08-05 | 2024-02-08 | Juno Therapeutics, Inc. | Chimeric antigen receptors specific for gprc5d and bcma |
WO2024044779A2 (en) | 2022-08-26 | 2024-02-29 | Juno Therapeutics, Inc. | Antibodies and chimeric antigen receptors specific for delta-like ligand 3 (dll3) |
WO2024054944A1 (en) | 2022-09-08 | 2024-03-14 | Juno Therapeutics, Inc. | Combination of a t cell therapy and continuous or intermittent dgk inhibitor dosing |
WO2024078995A1 (en) | 2022-10-15 | 2024-04-18 | Miltenyi Biotec B.V. & Co. KG | Transduction of gammadelta t cells with pseudotyped retroviral vectors |
WO2024092145A1 (en) | 2022-10-28 | 2024-05-02 | Kite Pharma, Inc. | Expedited administration of engineered lymphocytes |
TW202417643A (zh) | 2022-10-28 | 2024-05-01 | 美商凱特製藥公司 | 用於將免疫療法最佳化之因素 |
WO2024097905A1 (en) | 2022-11-02 | 2024-05-10 | Celgene Corporation | Methods of treatment with t cell therapy and immunomodulatory agent maintenance therapy |
WO2024098028A2 (en) | 2022-11-04 | 2024-05-10 | Umoja Biopharma, Inc. | Lentiviral particles displaying fusion molecules and uses thereof |
WO2024097992A2 (en) | 2022-11-04 | 2024-05-10 | Umoja Biopharma, Inc. | Particles displaying adhesion-molecule fusions |
WO2024129778A2 (en) | 2022-12-13 | 2024-06-20 | Juno Therapeutics, Inc. | Chimeric antigen receptors specific for baff-r and cd19 and methods and uses thereof |
US20240285762A1 (en) | 2023-02-28 | 2024-08-29 | Juno Therapeutics, Inc. | Cell therapy for treating systemic autoimmune diseases |
US11939565B1 (en) * | 2023-06-28 | 2024-03-26 | Trisk Bio Ltd. | Methods and systems for performing biotechnological processes |
US12013066B1 (en) | 2023-11-03 | 2024-06-18 | Trisk Bio Ltd. | Methods and systems for reversibly consummating fluidic connections |
Family Cites Families (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3586413A (en) * | 1969-03-25 | 1971-06-22 | Dale A Adams | Apparatus for providing energy communication between a moving and a stationary terminal |
US3955755A (en) * | 1975-04-25 | 1976-05-11 | The United States Of America As Represented By The United States Energy Research And Development Administration | Closed continuous-flow centrifuge rotor |
US4230685A (en) | 1979-02-28 | 1980-10-28 | Northwestern University | Method of magnetic separation of cells and the like, and microspheres for use therein |
US4321330A (en) * | 1980-04-04 | 1982-03-23 | Baker Fraser L | Tissue culture device |
US4452773A (en) | 1982-04-05 | 1984-06-05 | Canadian Patents And Development Limited | Magnetic iron-dextran microspheres |
US4632908A (en) * | 1984-05-03 | 1986-12-30 | Abbott Laboratories | Heating system for rotating members |
JPS614554A (ja) * | 1984-06-15 | 1986-01-10 | Hitachi Koki Co Ltd | 連続遠心分離ロ−タ |
US5266476A (en) * | 1985-06-18 | 1993-11-30 | Yeda Research & Development Co., Ltd. | Fibrous matrix for in vitro cell cultivation |
US4795698A (en) | 1985-10-04 | 1989-01-03 | Immunicon Corporation | Magnetic-polymer particles |
CA1335181C (en) * | 1988-10-11 | 1995-04-11 | R. Alan Hardwick | System for selective cell separation from cell concentrate |
AU4746590A (en) | 1988-12-28 | 1990-08-01 | Stefan Miltenyi | Methods and materials for high gradient magnetic separation of biological materials |
US5316667A (en) * | 1989-05-26 | 1994-05-31 | Baxter International Inc. | Time based interface detection systems for blood processing apparatus |
US6143508A (en) * | 1989-06-29 | 2000-11-07 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Device and process for cell capture and recovery |
US5242606A (en) * | 1990-06-04 | 1993-09-07 | Abaxis, Incorporated | Sample metering port for analytical rotor having overflow chamber |
US5200084A (en) | 1990-09-26 | 1993-04-06 | Immunicon Corporation | Apparatus and methods for magnetic separation |
DE4132965A1 (de) | 1991-10-04 | 1993-04-08 | Fresenius Ag | Vorrichtung zur trennung von medien in deren bestandteile |
WO1994009352A2 (en) * | 1992-10-14 | 1994-04-28 | Andrew George Bosanquet | Method and apparatus for conducting tests, particularly comparative tests |
JPH07502676A (ja) * | 1992-10-22 | 1995-03-23 | バクスター、インターナショナル、インコーポレイテッド | 静止および回転エレメント間の改良されたデータ伝送を有する血液処理システム |
ZA948564B (en) | 1993-11-19 | 1995-07-26 | Bristol Myers Squibb Co | Liquid separation apparatus and method |
US5705059A (en) | 1995-02-27 | 1998-01-06 | Miltenyi; Stefan | Magnetic separation apparatus |
DE69839047T2 (de) * | 1997-05-20 | 2009-01-15 | Zymequest, Inc., Beverly | Flüssigkeitsüberwachungssystem |
US5935051A (en) * | 1997-08-29 | 1999-08-10 | Beckman Instruments, Inc. | Blood separation device |
US5904840A (en) * | 1998-04-06 | 1999-05-18 | Dibella; Alberto | Apparatus for accurate centrifugal separation of miscible and immiscible media |
US6080581A (en) | 1998-07-02 | 2000-06-27 | Charles Daniel Anderson | Culture vessel for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using same |
BR9915734A (pt) * | 1998-10-15 | 2001-10-02 | Sangart Inc | Método para a produção de hemoglobina livre de estroma |
EP1043072A1 (fr) * | 1999-04-09 | 2000-10-11 | Jean-Denis Rochat | Dispositif de centrifugation et utilisation de ce dispositif |
EP1043071A1 (fr) * | 1999-04-09 | 2000-10-11 | Jean-Denis Rochat | Appareil de cetrifugation de liquide et utillisation de cet appareil |
US6537593B2 (en) * | 2000-10-30 | 2003-03-25 | Council Of Scientific And Industrial Research | Plant phenol as new hepatoprotective agents |
US20020144939A1 (en) * | 2001-04-09 | 2002-10-10 | Dolecek Victor D. | Miniaturized blood centrifuge having side mounted motor with belt drive |
US20020173034A1 (en) * | 2001-05-21 | 2002-11-21 | Emilio Barbera-Guillem | Centrifuge apparatus and methods for separating components from a cell culture device |
DE10127068A1 (de) * | 2001-05-23 | 2002-11-28 | Bio Medical Apherese Systeme G | Vorrichtung und Verfahren zum Inkubieren und Wiederabtrennen von Magnetteilchen in und von flüssige biologische Dispersionen |
US6673595B2 (en) * | 2001-08-27 | 2004-01-06 | Biocrystal, Ltd | Automated cell management system for growth and manipulation of cultured cells |
ATE479490T1 (de) * | 2001-10-11 | 2010-09-15 | Aviva Biosciences Corp | Verfahren zum trennen von seltenen zellen von fluidproben |
JP2003250882A (ja) * | 2001-12-28 | 2003-09-09 | Katsutoshi Naruse | 新規な灌流法を用いる人工臓器システム |
US7118522B2 (en) * | 2003-04-15 | 2006-10-10 | Beckman Coulter, Inc. | Centrifuge adapter |
EP2380970B1 (en) * | 2003-06-25 | 2017-12-20 | Cytori Therapeutics, Inc. | Systems and methods for separating and concentrating regenerative cells from tissue |
WO2005003738A2 (en) * | 2003-07-02 | 2005-01-13 | Gambro, Inc. | Monitoring and control system for blood processing |
US7456019B2 (en) * | 2004-06-30 | 2008-11-25 | Regenetech, Inc. | Three-dimensional cell to tissue development process |
WO2006047296A1 (en) * | 2004-10-22 | 2006-05-04 | Cryofacets, Inc. | System, chamber, and method for fractionation and elutriation of fluids containing particulate components |
JP4368810B2 (ja) * | 2005-01-28 | 2009-11-18 | テルモ株式会社 | フィルター装置および血液成分採取装置 |
WO2007024518A2 (en) * | 2005-08-22 | 2007-03-01 | Gambro Inc. | Apparatus and method for separating a composite liquid into at least two components |
JP4665673B2 (ja) * | 2005-09-02 | 2011-04-06 | パナソニック株式会社 | 光学分析装置 |
US20070102374A1 (en) * | 2005-11-04 | 2007-05-10 | Gambro, Inc. | Blood processing apparatus with controlled cell capture chamber and method background of the invention |
ES2660180T3 (es) | 2007-12-07 | 2018-03-21 | Miltenyi Biotec Gmbh | Sistemas y métodos para procesamiento de células |
KR101622231B1 (ko) | 2014-04-18 | 2016-05-18 | 엘지전자 주식회사 | 냉장고 |
EP3247808B1 (en) | 2015-01-21 | 2021-05-05 | Fred Hutchinson Cancer Research Center | Point-of-care and/or portable platform for gene therapy |
KR20230092033A (ko) | 2017-09-01 | 2023-06-23 | 론차 콜로그네 게엠베하 | 엔드-투-엔드 세포 요법의 자동화 |
WO2020061696A1 (en) | 2018-09-28 | 2020-04-02 | Octane Biotech Inc. | Magnetic separation |
KR20210110322A (ko) | 2018-12-28 | 2021-09-07 | 옥테인 바이오테크 인코포레이티드 | 제어된 환경 존을 포함하는 세포 배양 및 조직 공학 시스템 |
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