MA44486A - Procédés d'intervention précoce pour prévenir ou atténuer la toxicité - Google Patents

Procédés d'intervention précoce pour prévenir ou atténuer la toxicité

Info

Publication number
MA44486A
MA44486A MA044486A MA44486A MA44486A MA 44486 A MA44486 A MA 44486A MA 044486 A MA044486 A MA 044486A MA 44486 A MA44486 A MA 44486A MA 44486 A MA44486 A MA 44486A
Authority
MA
Morocco
Prior art keywords
prevent
early intervention
intervention methods
mitigate toxicity
mitigate
Prior art date
Application number
MA044486A
Other languages
English (en)
Inventor
Rebecca Gardner
Michael Jensen
Original Assignee
Seattle Childrens Hospital Dba Seattle Childrens Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58609964&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA44486(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Seattle Childrens Hospital Dba Seattle Childrens Res Inst filed Critical Seattle Childrens Hospital Dba Seattle Childrens Res Inst
Publication of MA44486A publication Critical patent/MA44486A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MA044486A 2016-03-22 2017-03-22 Procédés d'intervention précoce pour prévenir ou atténuer la toxicité MA44486A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662311906P 2016-03-22 2016-03-22
US201662417287P 2016-11-03 2016-11-03
US201662429722P 2016-12-02 2016-12-02

Publications (1)

Publication Number Publication Date
MA44486A true MA44486A (fr) 2019-01-30

Family

ID=58609964

Family Applications (2)

Application Number Title Priority Date Filing Date
MA71266A MA71266A (fr) 2016-03-22 2017-03-22 Procédés d'intervention précoce pour prévenir ou améliorer la toxicité
MA044486A MA44486A (fr) 2016-03-22 2017-03-22 Procédés d'intervention précoce pour prévenir ou atténuer la toxicité

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MA71266A MA71266A (fr) 2016-03-22 2017-03-22 Procédés d'intervention précoce pour prévenir ou améliorer la toxicité

Country Status (13)

Country Link
US (5) US11518814B2 (fr)
EP (3) EP4545143A3 (fr)
JP (3) JP7048571B2 (fr)
KR (1) KR20190021200A (fr)
CN (1) CN109476743A (fr)
AU (2) AU2017238218B2 (fr)
BR (1) BR112018069251A2 (fr)
CA (1) CA3018588A1 (fr)
ES (1) ES2907557T3 (fr)
MA (2) MA71266A (fr)
MX (1) MX2018011480A (fr)
RU (1) RU2018136877A (fr)
WO (1) WO2017165571A1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2949648T3 (es) 2012-12-20 2023-10-02 Purdue Research Foundation Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer
IL293714A (en) 2014-10-20 2022-08-01 Juno Therapeutics Inc Methods and compositions for dosing in adoptive cell therapy
EP4012415A3 (fr) 2015-12-04 2022-12-07 Juno Therapeutics, Inc. Procédés et compositions liés à la toxicité associée à une thérapie cellulaire
US11518814B2 (en) 2016-03-22 2022-12-06 Seattle Children's Hospital Early intervention methods to prevent or ameliorate toxicity
JP7282521B2 (ja) 2016-04-08 2023-05-29 パーデュー・リサーチ・ファウンデイション Ｃａｒ ｔ細胞療法のための方法および組成物
MA46963A (fr) * 2016-12-03 2019-10-09 Juno Therapeutics Inc Méthodes pour déterminer le dosage de céllules car-t
CN110612119B (zh) 2017-02-07 2024-10-29 西雅图儿童医院（Dba西雅图儿童研究所） 磷脂醚(ple)car t细胞肿瘤靶向(ctct)剂
ES2988795T3 (es) 2017-02-27 2024-11-21 Juno Therapeutics Inc Composiciones, artículos de fabricación y métodos relacionados con la dosificación en terapia celular
US11850262B2 (en) 2017-02-28 2023-12-26 Purdue Research Foundation Compositions and methods for CAR T cell therapy
US11564946B2 (en) 2017-11-01 2023-01-31 Juno Therapeutics, Inc. Methods associated with tumor burden for assessing response to a cell therapy
EP3716980A1 (fr) * 2017-12-01 2020-10-07 Juno Therapeutics, Inc. Procédés de dosage et de modulation de cellules génétiquement modifiées
BR112020014913A2 (pt) * 2018-01-22 2020-12-08 Seattle Children's Hospital (dba Seattle Children's Research Institute) Métodos para uso de células t car
SG11202007426XA (en) 2018-02-06 2020-09-29 Seattle Childrens Hospital Dba Seattle Childrens Res Inst Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors
US11103510B2 (en) * 2018-02-16 2021-08-31 Incyte Corporation JAK1 pathway inhibitors for the treatment of cytokine-related disorders
CA3091674A1 (fr) 2018-02-23 2019-08-29 Endocyte, Inc. Procede de sequencage pour therapie par lymphocytes t a car
US20210046159A1 (en) * 2018-03-09 2021-02-18 Ospedale San Raffaele S.R.L. Il-1 antagonist and toxicity induced by cell therapy
WO2019170147A1 (fr) * 2018-03-09 2019-09-12 科济生物医药（上海）有限公司 Méthode et composition de traitement de tumeurs
US20210263045A1 (en) * 2018-04-06 2021-08-26 The Board Of Regents Of The University Of Texas System Prediction and treatment of immunotherapeutic toxicity
WO2021028469A1 (fr) * 2019-08-12 2021-02-18 Sitokine Limited Compositions et méthodes de traitement du syndrome de libération de cytokines et de neurotoxicité
CN114286679A (zh) * 2019-08-14 2022-04-05 里格尔药品股份有限公司 阻断或改善细胞因子释放综合征的方法
US11045546B1 (en) 2020-03-30 2021-06-29 Cytodyn Inc. Methods of treating coronavirus infection
WO2022072515A1 (fr) * 2020-09-29 2022-04-07 Washington University Procédés pour déterminer un risque de neurotoxicité
CA3204374A1 (fr) 2020-12-08 2022-06-16 Incyte Corporation Inhibiteurs de la voie jak1 destines au traitement du vitiligo
FI4333840T3 (fi) 2021-05-03 2025-12-12 Incyte Corp Jak1-reitin estäjiä kyhmykutinan hoitoon

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US265209A (en) 1882-09-26 Automatic feeder for perforators
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4452773A (en) 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US5019369A (en) 1984-10-22 1991-05-28 Vestar, Inc. Method of targeting tumors in humans
US4690915A (en) 1985-08-08 1987-09-01 The United States Of America As Represented By The Department Of Health And Human Services Adoptive immunotherapy as a treatment modality in humans
US4795698A (en) 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
IN165717B (fr) 1986-08-07 1989-12-23 Battelle Memorial Institute
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5219740A (en) 1987-02-13 1993-06-15 Fred Hutchinson Cancer Research Center Retroviral gene transfer into diploid fibroblasts for gene therapy
EP0452342B1 (fr) 1988-12-28 1994-11-30 MILTENYI, Stefan Procedes et matieres pour la separation magnetique a gradient eleve de matieres biologiques
US5200084A (en) 1990-09-26 1993-04-06 Immunicon Corporation Apparatus and methods for magnetic separation
JP3150340B2 (ja) 1990-11-13 2001-03-26 イムネクス コーポレイション 二機能選択可能融合遺伝子
CA2147466A1 (fr) 1992-10-20 1994-04-28 Just P. J. Brakenhoff Antagonistes du recepteur de l'interleukine-6
US6080407A (en) * 1993-05-17 2000-06-27 The Picower Institute For Medical Research Diagnostic assays for MIF
JPH09500783A (ja) 1993-05-21 1997-01-28 ターゲッティッド ジェネティクス コーポレイション シトシンデアミナーゼ（ｃｄ）遺伝子に基づく二機能性選択融合遺伝子
US5827642A (en) 1994-08-31 1998-10-27 Fred Hutchinson Cancer Research Center Rapid expansion method ("REM") for in vitro propagation of T lymphocytes
DE19608753C1 (de) 1996-03-06 1997-06-26 Medigene Gmbh Transduktionssystem und seine Verwendung
WO1997034634A1 (fr) 1996-03-20 1997-09-25 Sloan-Kettering Institute For Cancer Research Produits de recombinaison d'anticorps diriges contre le gd2, constitues d'un fragment variable (fv) a chaine simple
WO2000014257A1 (fr) 1998-09-04 2000-03-16 Sloan-Kettering Institute For Cancer Research Recepteurs de fusion specifiques a l'antigene prostatique specifique membranaire et ses utilisations
US6410319B1 (en) 1998-10-20 2002-06-25 City Of Hope CD20-specific redirected T cells and their use in cellular immunotherapy of CD20+ malignancies
AU2001265346A1 (en) 2000-06-02 2001-12-17 Memorial Sloan-Kettering Cancer Center Artificial antigen presenting cells and methods of use thereof
JP5312721B2 (ja) 2000-11-07 2013-10-09 シティ・オブ・ホープ Ｃｄ１９特異的再指向免疫細胞
US7070995B2 (en) 2001-04-11 2006-07-04 City Of Hope CE7-specific redirected immune cells
US20090257994A1 (en) 2001-04-30 2009-10-15 City Of Hope Chimeric immunoreceptor useful in treating human cancers
US20030170238A1 (en) 2002-03-07 2003-09-11 Gruenberg Micheal L. Re-activated T-cells for adoptive immunotherapy
US7446190B2 (en) 2002-05-28 2008-11-04 Sloan-Kettering Institute For Cancer Research Nucleic acids encoding chimeric T cell receptors
US20050129671A1 (en) 2003-03-11 2005-06-16 City Of Hope Mammalian antigen-presenting T cells and bi-specific T cells
WO2007147623A2 (fr) * 2006-06-22 2007-12-27 Cellact Pharma Gmbh Nouvelle cible dans le traitement du syndrome de libération de cytokines (crs)
DK2856876T3 (en) 2007-03-30 2018-04-03 Memorial Sloan Kettering Cancer Center Constitutive expression of co-stimulatory ligands on adoptively transmitted T lymphocytes
EP2520643B8 (fr) 2007-12-07 2019-11-27 Miltenyi Biotec B.V. & Co. KG Systèmes de traitement d'échantillons et procédés
US8479118B2 (en) 2007-12-10 2013-07-02 Microsoft Corporation Switching search providers within a browser search box
US20120164718A1 (en) 2008-05-06 2012-06-28 Innovative Micro Technology Removable/disposable apparatus for MEMS particle sorting device
JP5173594B2 (ja) 2008-05-27 2013-04-03 キヤノン株式会社 管理装置、画像形成装置及びそれらの処理方法
CA2735456C (fr) 2008-08-26 2021-11-16 City Of Hope Procede et compositions pour fonctionnement ameliore d'effecteur antitumoral de lymphocytes t
TWI440469B (zh) 2008-09-26 2014-06-11 Chugai Pharmaceutical Co Ltd Improved antibody molecules
DK2496698T3 (en) 2009-11-03 2019-04-15 Hope City TRUNCATED EPIDERIMAL GROWTH FACTOR RECEPTOR (EGFRt) FOR TRUNCATED T-CELL SELECTION
JP6105472B2 (ja) 2010-09-16 2017-03-29 バリオファルム・アクチェンゲゼルシャフト 抗ｈｕＴＮＦＲ１抗体
PH12013501201A1 (en) 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
NZ743310A (en) 2011-03-23 2022-11-25 Fred Hutchinson Cancer Center Method and compositions for cellular immunotherapy
US8398282B2 (en) 2011-05-12 2013-03-19 Delphi Technologies, Inc. Vehicle front lighting assembly and systems having a variable tint electrowetting element
JP6368243B2 (ja) 2011-11-11 2018-08-08 フレッド ハッチンソン キャンサー リサーチ センター がんのためのサイクリンａ１に標的化されたｔ細胞免疫療法
EP2814846B1 (fr) 2012-02-13 2020-01-08 Seattle Children's Hospital d/b/a Seattle Children's Research Institute Récepteurs d'antigène chimères bispécifiques et utilisations thérapeutiques de ceux-ci
WO2013126726A1 (fr) 2012-02-22 2013-08-29 The Trustees Of The University Of Pennsylvania Lymphocytes t doubles transgéniques comportant un car et un tcr, et leurs procédés d'utilisation
JP6251734B2 (ja) 2012-05-03 2017-12-27 フレッド ハッチンソン キャンサー リサーチ センター 親和性増強型ｔ細胞受容体およびその作製方法
LT2872171T (lt) * 2012-07-13 2021-04-26 The Trustees Of The University Of Pennsylvania Car priešnavikinio aktyvumo toksiškumo reguliavimas
IL293944A (en) 2012-08-20 2022-08-01 Hutchinson Fred Cancer Res Method and preparations for cellular immunotherapy
CN104853766A (zh) 2012-10-02 2015-08-19 纪念斯隆-凯特琳癌症中心 用于免疫疗法的组合物和方法
CN104781789B (zh) 2012-12-20 2018-06-05 三菱电机株式会社 车载装置
UY35468A (es) 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
US9108442B2 (en) 2013-08-20 2015-08-18 Ricoh Company, Ltd. Image forming apparatus
IL284985B2 (en) * 2015-02-18 2023-03-01 Enlivex Therapeutics R& D Ltd Combined immunotherapy and cytokine control therapy for cancer treatment
WO2017035362A1 (fr) * 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Utilisation de composés inhibiteurs de la voie du complément pour atténuer des réponses immunitaires indésirables associées à une thérapie adoptive par lymphocytes t
WO2017040930A2 (fr) * 2015-09-03 2017-03-09 The Trustees Of The University Of Pennsylvania Biomarqueurs prédictifs du syndrome de libération de cytokines
US11518814B2 (en) * 2016-03-22 2022-12-06 Seattle Children's Hospital Early intervention methods to prevent or ameliorate toxicity
CN110461315B (zh) 2016-07-15 2025-05-02 诺华股份有限公司 使用与激酶抑制剂组合的嵌合抗原受体治疗和预防细胞因子释放综合征

Also Published As

Publication number Publication date
ES2907557T3 (es) 2022-04-25
US11518814B2 (en) 2022-12-06
AU2024205049A1 (en) 2024-08-15
JP2022088489A (ja) 2022-06-14
US20230212298A1 (en) 2023-07-06
EP3433276B1 (fr) 2021-12-22
US12098208B2 (en) 2024-09-24
CN109476743A (zh) 2019-03-15
EP4015536A1 (fr) 2022-06-22
MA71266A (fr) 2025-04-30
EP4545143A2 (fr) 2025-04-30
BR112018069251A2 (pt) 2019-01-22
US11760804B2 (en) 2023-09-19
AU2017238218A1 (en) 2018-10-11
MX2018011480A (es) 2019-03-28
RU2018136877A (ru) 2020-04-22
WO2017165571A1 (fr) 2017-09-28
JP7528143B2 (ja) 2024-08-05
US20230322937A1 (en) 2023-10-12
AU2017238218B2 (en) 2024-05-02
US20240425608A1 (en) 2024-12-26
EP3433276A1 (fr) 2019-01-30
US20190112379A1 (en) 2019-04-18
KR20190021200A (ko) 2019-03-05
EP4545143A3 (fr) 2025-07-23
JP7048571B2 (ja) 2022-04-05
JP2019509351A (ja) 2019-04-04
US20230091447A1 (en) 2023-03-23
JP2024156736A (ja) 2024-11-06
CA3018588A1 (fr) 2017-09-28

Similar Documents

Publication Publication Date Title
MA44486A (fr) Procédés d'intervention précoce pour prévenir ou atténuer la toxicité
FR25C1001I1 (fr) Compositions d'anticorps pour le traitement de tumeurs
MA45192A (fr) Traitement d'association
EP3430731A4 (fr) Architecture d'iugw
EP3353309A4 (fr) Compositions et méthodes pour l'édition génomique
EP3387025A4 (fr) Compositions d'émulsion inverse
EP3526328A4 (fr) Polythérapie pour l'inhibition de c3
EP3324840A4 (fr) Tensiomètre pour l'estimation de débit
EP3356612A4 (fr) Détail facilité pour membranes d'imperméabilisation pré-appliquées
EP3325963A4 (fr) Amélioration de l'estimation de globules
EP3040355A4 (fr) Modificateur d'asphalte et composition d'asphalte le contenant
EP3443293A4 (fr) Capteurs d'effort
EP3858368A4 (fr) Potentialisateur d'effet anticancéreux
EP3426349A4 (fr) Procédés et compositions pour inhiber l'expression de pmp22
EP3484444A4 (fr) Composition d'émulsion de pickering
FR3024138B1 (fr) Composition de mortier pour enduit ou revetement d'interieur
EP3322451A4 (fr) Réduction ou prévention électrochimique d'infections
EP3204028A4 (fr) Composition synergique pour l'arthrose
EP3431808A4 (fr) Butée d'arrêt
EP3344650A4 (fr) Aav-epo pour le traitement d'animaux de compagnie
FR3020758B1 (fr) Composition pour ameliorer l'hygiene buco-dentaire
EP3479837A4 (fr) Composition améliorant l'anémie rénale
EP3444345A4 (fr) Dérivé d'arnmicro-143
MA43764A (fr) Inhibiteur monovalent de l'interaction hutnfr1
EP3363288A4 (fr) Composition pour la destruction de microalgues ou de sphaerocarpus