|
WO2006036445A2
(en)
|
2004-09-24 |
2006-04-06 |
Trustees Of Dartmouth College |
Chimeric nk receptor and methods for treating cancer
|
|
DK2126054T3
(en)
|
2007-01-31 |
2016-10-03 |
Yeda Res & Dev |
REROUTED, GENETICALLY MODIFIED regulatory T cells and their use for suppressing autoimmune inflammatory disease AND
|
|
DK2856876T3
(en)
*
|
2007-03-30 |
2018-04-03 |
Memorial Sloan Kettering Cancer Center |
Constitutive expression of co-stimulatory ligands on adoptively transmitted T lymphocytes
|
|
CA3028038C
(en)
|
2007-05-11 |
2021-08-10 |
Altor Bioscience Corporation |
Fusion molecules and il-15 variants
|
|
DK2279253T3
(en)
*
|
2008-04-09 |
2017-02-13 |
Maxcyte Inc |
Construction and application of therapeutic compositions of freshly isolated cells
|
|
US9273283B2
(en)
|
2009-10-29 |
2016-03-01 |
The Trustees Of Dartmouth College |
Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
|
|
WO2011059836A2
(en)
|
2009-10-29 |
2011-05-19 |
Trustees Of Dartmouth College |
T cell receptor-deficient t cell compositions
|
|
US12492376B2
(en)
|
2009-10-29 |
2025-12-09 |
The Trustees Of Dartmouth College |
T-cell receptor-deficient T cell compositions
|
|
DE102010037622B4
(de)
*
|
2010-09-17 |
2012-07-12 |
Lophius Biosciences Gmbh |
Verfahren zum Nachweis, Differenzieren und Quantifizieren von T-Zellpopulationen mittels der Reverse Transkription quantitativen Real-Time PCR (RT-qPCR) Technologie
|
|
EP4385570A3
(en)
|
2010-09-21 |
2024-09-11 |
Altor BioScience, LLC |
Multimeric il-15 soluble fusion molecules and methods of making and using same
|
|
US11053299B2
(en)
|
2010-09-21 |
2021-07-06 |
Immunity Bio, Inc. |
Superkine
|
|
US10117895B2
(en)
*
|
2010-11-17 |
2018-11-06 |
Ben-Gurion University Of The Negev Research And Development Authority |
T-cell therapy to neurodegenerative diseases
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
WO2013033626A2
(en)
|
2011-08-31 |
2013-03-07 |
Trustees Of Dartmouth College |
Nkp30 receptor targeted therapeutics
|
|
US9272002B2
(en)
|
2011-10-28 |
2016-03-01 |
The Trustees Of The University Of Pennsylvania |
Fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting
|
|
CA2868121C
(en)
*
|
2012-03-23 |
2021-06-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mesothelin chimeric antigen receptors
|
|
CN110511278B
(zh)
|
2012-05-07 |
2024-08-09 |
达特茅斯大学理事会 |
抗b7-h6抗体、融合蛋白及其使用方法
|
|
CN104853766A
(zh)
|
2012-10-02 |
2015-08-19 |
纪念斯隆-凯特琳癌症中心 |
用于免疫疗法的组合物和方法
|
|
US10117896B2
(en)
|
2012-10-05 |
2018-11-06 |
The Trustees Of The University Of Pennsylvania |
Use of a trans-signaling approach in chimeric antigen receptors
|
|
ES2949648T3
(es)
|
2012-12-20 |
2023-10-02 |
Purdue Research Foundation |
Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer
|
|
SG11201505858VA
(en)
|
2013-01-28 |
2015-09-29 |
St Jude Childrens Res Hospital |
A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease
|
|
WO2014130635A1
(en)
|
2013-02-20 |
2014-08-28 |
Novartis Ag |
Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells
|
|
EP2958943B1
(en)
|
2013-02-20 |
2019-09-11 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
|
|
MX378463B
(es)
*
|
2013-02-26 |
2025-03-10 |
Memorial Sloan Kettering Cancer Center |
Composiciones y usos de las mismas para inmunoterapia.
|
|
US9745368B2
(en)
|
2013-03-15 |
2017-08-29 |
The Trustees Of The University Of Pennsylvania |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
KR102466666B1
(ko)
*
|
2013-03-15 |
2022-11-15 |
메모리얼 슬로안 케터링 캔서 센터 |
면역치료용 조성물 및 방법
|
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
|
CA3185368A1
(en)
*
|
2013-04-03 |
2014-10-09 |
Memorial Sloan-Kettering Cancer Center |
Effective generation of tumor-targeted t cells derived from pluripotent stem cells
|
|
EP3783098A1
(en)
|
2013-05-14 |
2021-02-24 |
Board Of Regents, The University Of Texas System |
Human application of engineered chimeric antigen receptor (car) t-cells
|
|
CN105829349B
(zh)
|
2013-10-15 |
2023-02-03 |
斯克利普斯研究所 |
肽嵌合抗原受体t细胞开关和其用途
|
|
WO2015090230A1
(en)
|
2013-12-19 |
2015-06-25 |
Novartis Ag |
Human mesothelin chimeric antigen receptors and uses thereof
|
|
JP6793902B2
(ja)
|
2013-12-20 |
2020-12-02 |
ノバルティス アーゲー |
調節可能キメラ抗原受容体
|
|
ES2963718T3
(es)
|
2014-01-21 |
2024-04-01 |
Novartis Ag |
Capacidad presentadora de antígenos de células CAR-T potenciada mediante introducción conjunta de moléculas co-estimuladoras
|
|
KR102375998B1
(ko)
|
2014-02-14 |
2022-03-21 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
키메라 항원 수용체 및 제조방법
|
|
JP2017511376A
(ja)
|
2014-03-21 |
2017-04-20 |
アッヴィ・インコーポレイテッド |
抗egfr抗体及び抗体薬物コンジュゲート
|
|
PL3888674T3
(pl)
|
2014-04-07 |
2024-09-23 |
Novartis Ag |
Leczenie nowotworu złośliwego z zastosowaniem chimerycznego receptora antygenowego anty-CD19
|
|
CA2946312A1
(en)
|
2014-04-23 |
2015-10-29 |
Juno Therapeutics, Inc. |
Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy
|
|
EP3805371A1
(en)
|
2014-05-15 |
2021-04-14 |
National University of Singapore |
Modified natural killer cells and uses thereof
|
|
PL3160498T3
(pl)
|
2014-06-30 |
2022-02-21 |
Altor Bioscience Corporation |
Cząsteczki na bazie IL-15 i sposoby ich zastosowania
|
|
WO2016011210A2
(en)
|
2014-07-15 |
2016-01-21 |
Juno Therapeutics, Inc. |
Engineered cells for adoptive cell therapy
|
|
JP7054622B2
(ja)
|
2014-07-21 |
2022-04-14 |
ノバルティス アーゲー |
ヒト化抗bcmaキメラ抗原受容体を使用した癌の処置
|
|
EP3722316A1
(en)
|
2014-07-21 |
2020-10-14 |
Novartis AG |
Treatment of cancer using a cd33 chimeric antigen receptor
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
BR112017000939A2
(pt)
|
2014-07-21 |
2017-11-14 |
Novartis Ag |
tratamento de câncer usando um receptor antigênico quimérico de cll-1
|
|
ES2791248T3
(es)
|
2014-08-19 |
2020-11-03 |
Novartis Ag |
Receptor antigénico quimérico (CAR) anti-CD123 para su uso en el tratamiento del cáncer
|
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
|
US10577417B2
(en)
|
2014-09-17 |
2020-03-03 |
Novartis Ag |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
CN114107424A
(zh)
|
2014-10-08 |
2022-03-01 |
诺华股份有限公司 |
预测针对嵌合抗原受体疗法的治疗应答性的生物标志及其用途
|
|
IL293714A
(en)
|
2014-10-20 |
2022-08-01 |
Juno Therapeutics Inc |
Methods and compositions for dosing in adoptive cell therapy
|
|
CN107206024B
(zh)
|
2014-10-31 |
2021-12-03 |
宾夕法尼亚大学董事会 |
改变cart细胞中的基因表达及其用途
|
|
EP3215601B1
(en)
|
2014-11-05 |
2020-05-27 |
Juno Therapeutics, Inc. |
Methods for transduction and cell processing
|
|
KR101697473B1
(ko)
|
2014-11-26 |
2017-01-18 |
주식회사 녹십자랩셀 |
T 세포를 이용한 자연살해세포의 배양방법
|
|
KR20250067192A
(ko)
|
2014-12-03 |
2025-05-14 |
주노 쎄러퓨티크스 인코퍼레이티드 |
입양 세포 치료를 위한 방법 및 조성물
|
|
KR20240130831A
(ko)
|
2014-12-05 |
2024-08-29 |
메모리얼 슬로안 케터링 캔서 센터 |
B-세포 성숙화 항원을 표적화하는 키메라 항원 수용체 및 그의 용도
|
|
CN113683711A
(zh)
|
2014-12-05 |
2021-11-23 |
纪念斯隆-凯特琳癌症中心 |
靶向g-蛋白偶联受体的嵌合抗原受体及其用途
|
|
JP7174522B2
(ja)
|
2014-12-05 |
2022-11-17 |
メモリアル スローン ケタリング キャンサー センター |
Fc受容体様5を標的とするキメラ抗原受容体およびその使用
|
|
CN113429484A
(zh)
|
2014-12-05 |
2021-09-24 |
纪念斯隆-凯特琳癌症中心 |
靶向g-蛋白偶联受体的抗体和使用方法
|
|
IL253149B2
(en)
|
2014-12-29 |
2023-11-01 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
MA41346A
(fr)
|
2015-01-12 |
2017-11-21 |
Juno Therapeutics Inc |
Eléments régulateurs post-transcriptionnels d'hépatite modifiée
|
|
MX2017009254A
(es)
|
2015-01-16 |
2017-10-12 |
Juno Therapeutics Inc |
Anticuerpos y receptores de antigeno quimerico especificos para ror1.
|
|
US11459390B2
(en)
|
2015-01-16 |
2022-10-04 |
Novartis Ag |
Phosphoglycerate kinase 1 (PGK) promoters and methods of use for expressing chimeric antigen receptor
|
|
KR102329836B1
(ko)
|
2015-01-26 |
2021-11-19 |
셀렉티스 |
암 면역치료를 위한 항-CLL1 특이적 단일-체인 키메라 항원 수용체들(scCARS)
|
|
CN114058582A
(zh)
|
2015-01-26 |
2022-02-18 |
菲特治疗公司 |
用于诱导造血细胞分化的方法和组合物
|
|
US11161907B2
(en)
|
2015-02-02 |
2021-11-02 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
JP6744318B2
(ja)
*
|
2015-02-06 |
2020-08-26 |
ヒート バイオロジクス,インコーポレイテッド |
ワクチンおよび共刺激分子を共発現するベクター
|
|
WO2016154621A1
(en)
|
2015-03-26 |
2016-09-29 |
The California Institute For Biomedical Research |
SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
|
|
JP6961490B2
(ja)
|
2015-04-08 |
2021-11-05 |
ノバルティス アーゲー |
Cd20療法、cd22療法、およびcd19キメラ抗原受容体(car)発現細胞との併用療法
|
|
EP3283113A4
(en)
|
2015-04-15 |
2018-12-05 |
The California Institute for Biomedical Research |
Optimized pne-based chimeric receptor t cell switches and uses thereof
|
|
WO2016166568A1
(en)
|
2015-04-16 |
2016-10-20 |
Juno Therapeutics Gmbh |
Methods, kits and apparatus for expanding a population of cells
|
|
PT3283508T
(pt)
|
2015-04-17 |
2021-06-21 |
Alpine Immune Sciences Inc |
Proteínas imuno modulatórias com afinidades afináveis
|
|
WO2016168595A1
(en)
|
2015-04-17 |
2016-10-20 |
Barrett David Maxwell |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
US12128069B2
(en)
|
2015-04-23 |
2024-10-29 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
IL303905A
(en)
|
2015-05-18 |
2023-08-01 |
Tcr2 Therapeutics Inc |
Compositions and methods for TCR programming using fusion proteins
|
|
AU2016271147B2
(en)
|
2015-05-29 |
2022-09-08 |
Juno Therapeutics, Inc. |
Composition and methods for regulating inhibitory interactions in genetically engineered cells
|
|
MA42895A
(fr)
|
2015-07-15 |
2018-05-23 |
Juno Therapeutics Inc |
Cellules modifiées pour thérapie cellulaire adoptive
|
|
AR105433A1
(es)
|
2015-07-21 |
2017-10-04 |
Novartis Ag |
Métodos para mejorar la eficacia y expansión de las células inmunes
|
|
GB201513540D0
(en)
|
2015-07-31 |
2015-09-16 |
King S College London |
Therapeutic agents
|
|
IL257105B
(en)
|
2015-07-31 |
2022-09-01 |
Univ Minnesota |
Modified cells and methods of therapy
|
|
EP3328994A4
(en)
|
2015-07-31 |
2019-04-17 |
Memorial Sloan-Kettering Cancer Center |
CD56-Faced Antigen-Binding Proteins and Uses Thereof
|
|
EP3331913A1
(en)
|
2015-08-07 |
2018-06-13 |
Novartis AG |
Treatment of cancer using chimeric cd3 receptor proteins
|
|
WO2017040930A2
(en)
|
2015-09-03 |
2017-03-09 |
The Trustees Of The University Of Pennsylvania |
Biomarkers predictive of cytokine release syndrome
|
|
MX2018003144A
(es)
*
|
2015-09-14 |
2018-09-11 |
Alpine Immune Sciences Inc |
Dominios de superfamilia de inmunoglobulina de variante ajustable y terapia con células genéticamente modificadas.
|
|
CN108289954B
(zh)
|
2015-09-24 |
2022-05-31 |
阿布维特罗有限责任公司 |
Hiv抗体组合物和使用方法
|
|
US10928392B2
(en)
|
2015-09-25 |
2021-02-23 |
Abvitro Llc |
High throughput process for T cell receptor target identification of natively-paired T cell receptor sequences
|
|
KR20180125435A
(ko)
*
|
2015-09-25 |
2018-11-23 |
알토 바이오사이언스 코포레이션 |
이식편 대 종양 활성을 현저하게 향상시키는 인터루킨-15 수퍼아고니스트
|
|
MA45489A
(fr)
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics Gmbh |
Procédés de culture de cellules, kits et appareil associés
|
|
AU2016341527B2
(en)
|
2015-10-22 |
2023-04-27 |
Juno Therapeutics Gmbh |
Methods, kits, agents and apparatuses for transduction
|
|
MA45488A
(fr)
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics Gmbh |
Procédés, kits et appareil de culture de cellules
|
|
KR20180069903A
(ko)
|
2015-11-02 |
2018-06-25 |
파이브 프라임 테라퓨틱스, 인크. |
Cd80 세포외 도메인 폴리펩타이드 및 이들의 암 치료에서의 용도
|
|
CN115806940A
(zh)
|
2015-11-04 |
2023-03-17 |
菲特治疗公司 |
多能细胞的基因组工程改造
|
|
EP3371301A4
(en)
|
2015-11-04 |
2019-06-26 |
Fate Therapeutics, Inc. |
METHOD AND COMPOSITIONS FOR INDUCING THE DIFFERENTIATION OF HEMATOPOIETIC CELLS
|
|
MA44314A
(fr)
|
2015-11-05 |
2018-09-12 |
Juno Therapeutics Inc |
Récepteurs chimériques contenant des domaines induisant traf, et compositions et méthodes associées
|
|
WO2017079703A1
(en)
|
2015-11-05 |
2017-05-11 |
Juno Therapeutics, Inc. |
Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy
|
|
CA3007258A1
(en)
|
2015-12-03 |
2017-06-08 |
Mark L. Bonyhadi |
Compositions and methods for reducing immune responses against cell therapies
|
|
EP4212547A1
(en)
|
2015-12-03 |
2023-07-19 |
Juno Therapeutics, Inc. |
Modified chimeric receptors and related compositions and methods
|
|
WO2017096120A1
(en)
|
2015-12-04 |
2017-06-08 |
Memorial Sloan-Kettering Cancer Center |
Antibodies targeting fc receptor-like 5 and methods of use
|
|
HK1257295A1
(zh)
|
2015-12-04 |
2019-10-18 |
Novartis Ag |
用於免疫肿瘤学的组合物和方法
|
|
EP4012415A3
(en)
|
2015-12-04 |
2022-12-07 |
Juno Therapeutics, Inc. |
Methods and compositions related to toxicity associated with cell therapy
|
|
EP3393504B1
(en)
|
2015-12-22 |
2025-09-24 |
Novartis AG |
Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
|
|
KR20180105709A
(ko)
|
2016-02-05 |
2018-09-28 |
시티 오브 호프 |
중추 신경계의 암의 치료를 위한 조작된 t 세포의 투여
|
|
US11780934B2
(en)
|
2016-02-05 |
2023-10-10 |
Institut Pasteur |
Use of inhibitors of ADAM12 as adjuvants in tumor therapies
|
|
WO2017161212A1
(en)
|
2016-03-16 |
2017-09-21 |
Juno Therapeutics, Inc. |
Methods for adaptive design of a treatment regimen and related treatments
|
|
MA43758A
(fr)
|
2016-03-16 |
2018-11-28 |
Yuan Ji |
Procédés pour déterminer le dosage d'un agent thérapeutique et traitements associés
|
|
US11518814B2
(en)
|
2016-03-22 |
2022-12-06 |
Seattle Children's Hospital |
Early intervention methods to prevent or ameliorate toxicity
|
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
|
JP7282521B2
(ja)
|
2016-04-08 |
2023-05-29 |
パーデュー・リサーチ・ファウンデイション |
Car t細胞療法のための方法および組成物
|
|
WO2017180587A2
(en)
|
2016-04-11 |
2017-10-19 |
Obsidian Therapeutics, Inc. |
Regulated biocircuit systems
|
|
IL262366B2
(en)
|
2016-04-15 |
2024-07-01 |
Alpine Immune Sciences Inc |
Immunomodulatory proteins and CD80 variants and their uses
|
|
MX2018013445A
(es)
|
2016-05-06 |
2019-09-09 |
Juno Therapeutics Inc |
Celulas diseñadas geneticamente y metodos para obtener las mismas.
|
|
MX388294B
(es)
|
2016-05-27 |
2025-03-19 |
Aadigen Llc |
Peptidos y nanoparticulas para suministro intracelular de moleculas editoras de genoma.
|
|
EP3463401A4
(en)
|
2016-06-03 |
2020-01-22 |
Memorial Sloan Kettering Cancer Center |
ADOPTIVE CELL THERAPIES AS EARLY TREATMENT OPTIONS
|
|
MA45341A
(fr)
|
2016-06-06 |
2019-04-10 |
Hutchinson Fred Cancer Res |
Procédés de traitement de malignités de lymphocytes b au moyen d'une thérapie cellulaire adoptive
|
|
AU2017277920A1
(en)
|
2016-06-08 |
2019-01-03 |
Abbvie Inc. |
Anti-CD98 antibodies and antibody drug conjugates
|
|
JP2019526529A
(ja)
|
2016-06-08 |
2019-09-19 |
アッヴィ・インコーポレイテッド |
抗b7−h3抗体及び抗体薬物コンジュゲート
|
|
UY37278A
(es)
|
2016-06-08 |
2018-01-31 |
Abbvie Inc |
Anticuerpos anti-b7-h3 y conjugados de fármaco y anticuerpos
|
|
MX2018015285A
(es)
|
2016-06-08 |
2019-09-18 |
Abbvie Inc |
Anticuerpos anti-b7-h3 y conjugados de anticuerpo y farmaco.
|
|
AU2017277916A1
(en)
|
2016-06-08 |
2019-01-03 |
Abbvie Inc. |
Anti-CD98 antibodies and antibody drug conjugates
|
|
US20200002432A1
(en)
|
2016-06-08 |
2020-01-02 |
Abbvie Inc. |
Anti-cd98 antibodies and antibody drug conjugates
|
|
ES2988783T3
(es)
*
|
2016-06-22 |
2024-11-21 |
David Klatzmann |
Linfocitos T genéticamente modificados
|
|
WO2018005559A1
(en)
|
2016-06-27 |
2018-01-04 |
Juno Therapeutics, Inc. |
Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
|
|
MA45491A
(fr)
|
2016-06-27 |
2019-05-01 |
Juno Therapeutics Inc |
Épitopes à restriction cmh-e, molécules de liaison et procédés et utilisations associés
|
|
WO2018022945A1
(en)
|
2016-07-28 |
2018-02-01 |
Alpine Immune Sciences, Inc. |
Cd112 variant immunomodulatory proteins and uses thereof
|
|
US11471488B2
(en)
|
2016-07-28 |
2022-10-18 |
Alpine Immune Sciences, Inc. |
CD155 variant immunomodulatory proteins and uses thereof
|
|
CA3031955A1
(en)
|
2016-07-29 |
2018-02-01 |
Juno Therapeutics, Inc. |
Immunomodulatory polypeptides and related compositions and methods
|
|
WO2018023094A1
(en)
|
2016-07-29 |
2018-02-01 |
Juno Therapeutics, Inc. |
Methods for assessing the presence or absence of replication competent virus
|
|
KR20230107408A
(ko)
|
2016-07-29 |
2023-07-14 |
주노 쎄러퓨티크스 인코퍼레이티드 |
항-cd19 항체에 대한 항-이디오타입 항체
|
|
JP7109789B2
(ja)
|
2016-08-02 |
2022-08-01 |
ティーシーアール2 セラピューティクス インク. |
融合タンパク質を使用したtcrの再プログラム化のための組成物及び方法
|
|
WO2018049420A1
(en)
|
2016-09-12 |
2018-03-15 |
Juno Therapeutics, Inc. |
Perfusion bioreactor bag assemblies
|
|
WO2018052947A1
(en)
*
|
2016-09-16 |
2018-03-22 |
Baylor College Of Medicine |
Platform for activation and expansion of virus-specific t-cells
|
|
WO2018057825A1
(en)
*
|
2016-09-23 |
2018-03-29 |
The Curators Of The University Of Missouri |
Antigen-specific immune modulation
|
|
GB201616238D0
(en)
*
|
2016-09-23 |
2016-11-09 |
Adaptimmune Ltd |
Modified T cells
|
|
EP4353319A3
(en)
|
2016-09-28 |
2024-06-05 |
Atossa Therapeutics, Inc. |
Methods of adoptive cell therapy
|
|
KR20190062505A
(ko)
|
2016-10-03 |
2019-06-05 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Hpv-특이적 결합 분자
|
|
ES2875959T3
(es)
|
2016-10-07 |
2021-11-11 |
Tcr2 Therapeutics Inc |
Composiciones y métodos para reprogramación de receptores de linfocitos T mediante el uso de proteínas de fusión
|
|
WO2018067992A1
(en)
|
2016-10-07 |
2018-04-12 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
|
CA3040123A1
(en)
|
2016-10-11 |
2018-04-19 |
University Of Miami |
Vectors and vaccine cells for immunity against zika virus
|
|
MA46649A
(fr)
|
2016-10-13 |
2019-08-21 |
Juno Therapeutics Inc |
Méthodes et compositions d'immunothérapie impliquant des modulateurs de la voie métabolique du tryptophane
|
|
JP7181862B2
(ja)
|
2016-10-18 |
2022-12-01 |
リージェンツ オブ ザ ユニバーシティ オブ ミネソタ |
腫瘍浸潤リンパ球および治療の方法
|
|
US11174306B2
(en)
|
2016-10-19 |
2021-11-16 |
The Scripps Research Institute |
Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
|
|
SG11201903306SA
(en)
|
2016-10-21 |
2019-05-30 |
Altor Bioscience Corp |
Multimeric il-15-based molecules
|
|
CN110139669A
(zh)
|
2016-11-03 |
2019-08-16 |
朱诺治疗学股份有限公司 |
T细胞疗法和btk抑制剂的组合疗法
|
|
MA46716A
(fr)
|
2016-11-03 |
2019-09-11 |
Juno Therapeutics Inc |
Polythérapie de thérapie cellulaire et d'inhibiteur de la microglie
|
|
AU2017363311A1
(en)
|
2016-11-22 |
2019-06-13 |
TCR2 Therapeutics Inc. |
Compositions and methods for TCR reprogramming using fusion proteins
|
|
MA46963A
(fr)
|
2016-12-03 |
2019-10-09 |
Juno Therapeutics Inc |
Méthodes pour déterminer le dosage de céllules car-t
|
|
AU2017368332A1
(en)
|
2016-12-03 |
2019-06-13 |
Juno Therapeutics, Inc. |
Methods for modulation of CAR-T cells
|
|
CN110545826A
(zh)
|
2016-12-03 |
2019-12-06 |
朱诺治疗学股份有限公司 |
用于与激酶抑制剂组合使用治疗性t细胞的方法和组合物
|
|
US20190350978A1
(en)
|
2016-12-05 |
2019-11-21 |
Juno Therapeutics, Inc. |
Production of engineered cells for adoptive cell therapy
|
|
SG11201906213UA
(en)
|
2017-01-10 |
2019-08-27 |
Intrexon Corp |
Modulating expression of polypeptides via new gene switch expression systems
|
|
CN110691792A
(zh)
|
2017-01-10 |
2020-01-14 |
朱诺治疗学股份有限公司 |
细胞疗法的表观遗传学分析及相关方法
|
|
CN110418802A
(zh)
|
2017-01-20 |
2019-11-05 |
朱诺治疗学有限公司 |
细胞表面缀合物及相关的细胞组合物和方法
|
|
CN110612119B
(zh)
|
2017-02-07 |
2024-10-29 |
西雅图儿童医院(Dba西雅图儿童研究所) |
磷脂醚(ple)car t细胞肿瘤靶向(ctct)剂
|
|
MX2019009552A
(es)
|
2017-02-17 |
2019-10-02 |
Hutchinson Fred Cancer Res |
Terapias de combinacion para el tratamiento de canceres relacionados con el antigeno de maduracion de celulas b (bcma) y trastornos autoinmunitarios.
|
|
ES2988795T3
(es)
|
2017-02-27 |
2024-11-21 |
Juno Therapeutics Inc |
Composiciones, artículos de fabricación y métodos relacionados con la dosificación en terapia celular
|
|
US11850262B2
(en)
|
2017-02-28 |
2023-12-26 |
Purdue Research Foundation |
Compositions and methods for CAR T cell therapy
|
|
AU2018234640C9
(en)
|
2017-03-14 |
2024-10-03 |
Juno Therapeutics, Inc. |
Methods for cryogenic storage
|
|
KR20250083578A
(ko)
|
2017-03-16 |
2025-06-10 |
알파인 이뮨 사이언시즈, 인코포레이티드 |
Cd80 변이체 면역조절 단백질 및 그의 용도
|
|
US11732022B2
(en)
|
2017-03-16 |
2023-08-22 |
Alpine Immune Sciences, Inc. |
PD-L2 variant immunomodulatory proteins and uses thereof
|
|
EP3601561A2
(en)
|
2017-03-22 |
2020-02-05 |
Novartis AG |
Compositions and methods for immunooncology
|
|
CA3056439A1
(en)
|
2017-03-27 |
2018-10-04 |
National University Of Singapore |
Truncated nkg2d chimeric receptors and uses thereof in natural killer cell immunotherapy
|
|
SG11201908337VA
(en)
|
2017-03-27 |
2019-10-30 |
Nat Univ Singapore |
Stimulatory cell lines for ex vivo expansion and activation of natural killer cells
|
|
WO2018187260A1
(en)
|
2017-04-04 |
2018-10-11 |
Heat Biologics, Inc. |
Intratumoral vaccination
|
|
AU2018250336B2
(en)
|
2017-04-07 |
2025-02-20 |
Juno Therapeutics, Inc. |
Engineered cells expressing prostate-specific membrane antigen (PSMA) or a modified form thereof and related methods
|
|
EP4317422A3
(en)
*
|
2017-04-13 |
2024-05-01 |
Senti Biosciences, Inc. |
Combinatorial cancer immunotherapy
|
|
MA54103A
(fr)
|
2017-04-14 |
2021-09-15 |
Juno Therapeutics Inc |
Procédés d'évaluation de la glycosylation de surface cellulaire
|
|
EA201992469A1
(ru)
|
2017-04-18 |
2020-05-27 |
Фуджифилм Селльюлар Дайнамикс, Инк. |
Антигенспецифические иммунные эффекторные клетки
|
|
CN110753555A
(zh)
|
2017-04-19 |
2020-02-04 |
得克萨斯州大学系统董事会 |
表达工程化抗原受体的免疫细胞
|
|
SI3612624T1
(sl)
*
|
2017-04-21 |
2025-03-31 |
Ospedale San Raffaele S.R.L. |
Genska terapija
|
|
EP4647493A2
(en)
|
2017-04-27 |
2025-11-12 |
Juno Therapeutics, Inc. |
Oligomeric particle reagents and methods of use thereof
|
|
MX2019012849A
(es)
|
2017-04-28 |
2019-11-28 |
Five Prime Therapeutics Inc |
Metodos de tratamiento con polipeptidos del dominio extracelular del cd80.
|
|
DK3618842T3
(da)
|
2017-05-01 |
2024-01-02 |
Juno Therapeutics Inc |
Kombination af en celleterapi og en immunomodulerende forbindelse
|
|
US11166985B2
(en)
|
2017-05-12 |
2021-11-09 |
Crispr Therapeutics Ag |
Materials and methods for engineering cells and uses thereof in immuno-oncology
|
|
JP7356354B2
(ja)
|
2017-05-12 |
2023-10-04 |
クリスパー セラピューティクス アクチェンゲゼルシャフト |
細胞の操作のための材料及び方法並びに免疫腫瘍学におけるその使用
|
|
KR102460173B1
(ko)
*
|
2017-05-26 |
2022-10-31 |
주식회사 지씨셀 |
형질전환된 t세포를 이용한 자연살해세포의 배양방법
|
|
WO2018223101A1
(en)
|
2017-06-02 |
2018-12-06 |
Juno Therapeutics, Inc. |
Articles of manufacture and methods for treatment using adoptive cell therapy
|
|
WO2018223098A1
(en)
|
2017-06-02 |
2018-12-06 |
Juno Therapeutics, Inc. |
Articles of manufacture and methods related to toxicity associated with cell therapy
|
|
EP3538645B1
(en)
|
2017-06-20 |
2021-01-20 |
Institut Curie |
Immune cells defective for suv39h1
|
|
AU2018288863A1
(en)
|
2017-06-22 |
2020-01-30 |
Board Of Regents, The University Of Texas System |
Methods for producing regulatory immune cells and uses thereof
|
|
CA3067602A1
(en)
|
2017-06-29 |
2019-01-03 |
Juno Therapeutics, Inc. |
Mouse model for assessing toxicities associated with immunotherapies
|
|
EP3645036A1
(en)
|
2017-06-30 |
2020-05-06 |
Cellectis |
Cellular immunotherapy for repetitive administration
|
|
JP2020530307A
(ja)
|
2017-06-30 |
2020-10-22 |
インティマ・バイオサイエンス,インコーポレーテッド |
遺伝子治療のためのアデノ随伴ウイルスベクター
|
|
US20230242654A1
(en)
|
2017-07-29 |
2023-08-03 |
Juno Therapeutics, Inc. |
Reagents for expanding cells expressing recombinant receptors
|
|
MX2020001491A
(es)
|
2017-08-09 |
2020-08-06 |
Juno Therapeutics Inc |
Metodos y composiciones para preparar celulas geneticamente modificadas.
|
|
ES2959953T3
(es)
|
2017-08-09 |
2024-02-29 |
Juno Therapeutics Inc |
Métodos para producir composiciones celulares genéticamente modificadas y composiciones relacionadas
|
|
US20210071258A1
(en)
|
2017-09-01 |
2021-03-11 |
Juno Therapeutics, Inc. |
Gene expression and assessment of risk of developing toxicity following cell therapy
|
|
EP3679370A1
(en)
|
2017-09-07 |
2020-07-15 |
Juno Therapeutics, Inc. |
Methods of identifying cellular attributes related to outcomes associated with cell therapy
|
|
CN109517820B
(zh)
|
2017-09-20 |
2021-09-24 |
北京宇繁生物科技有限公司 |
一种靶向HPK1的gRNA以及HPK1基因编辑方法
|
|
EP3692063A1
(en)
|
2017-10-03 |
2020-08-12 |
Juno Therapeutics, Inc. |
Hpv-specific binding molecules
|
|
CA3077509A1
(en)
|
2017-10-10 |
2019-04-18 |
Alpine Immune Sciences, Inc. |
Ctla-4 variant immunomodulatory proteins and uses thereof
|
|
KR102823603B1
(ko)
|
2017-10-12 |
2025-06-23 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
면역요법을 위한 t 세포 수용체
|
|
JP7710644B2
(ja)
*
|
2017-10-12 |
2025-07-22 |
アイセル・ジーン・セラピューティクス・インコーポレイテッド |
複数の抗原を標的とするcompoundキメラ抗原受容体(cCAR)の組成物およびその使用方法
|
|
KR20200086278A
(ko)
|
2017-10-18 |
2020-07-16 |
노파르티스 아게 |
선택적 단백질 분해를 위한 조성물 및 방법
|
|
IL320945A
(en)
|
2017-10-18 |
2025-07-01 |
Alpine Immune Sciences Inc |
Immunomodulatory proteins, ligands for ICOs, and compositions and methods related thereto
|
|
US12031975B2
(en)
|
2017-11-01 |
2024-07-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
|
KR20200074997A
(ko)
|
2017-11-01 |
2020-06-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
B-세포 성숙 항원에 특이적인 항체 및 키메릭 항원 수용체
|
|
WO2019089982A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Method of assessing activity of recombinant antigen receptors
|
|
PL3703750T3
(pl)
|
2017-11-01 |
2025-04-07 |
Juno Therapeutics, Inc. |
Chimeryczne receptory antygenowe specyficzne dla antygenu dojrzewania komórek b i kodujące polinukleotydy
|
|
US11564946B2
(en)
|
2017-11-01 |
2023-01-31 |
Juno Therapeutics, Inc. |
Methods associated with tumor burden for assessing response to a cell therapy
|
|
SG11202003688PA
(en)
|
2017-11-01 |
2020-05-28 |
Juno Therapeutics Inc |
Process for generating therapeutic compositions of engineered cells
|
|
EP3704229B1
(en)
|
2017-11-01 |
2023-12-20 |
Juno Therapeutics, Inc. |
Process for producing a t cell composition
|
|
BR112020008478A2
(pt)
|
2017-11-01 |
2020-10-20 |
Editas Medicine, Inc. |
métodos, composições e componentes para edição de crispr-cas9 de tgfbr2 em células t para imunota-rapia
|
|
CA3080395A1
(en)
|
2017-11-06 |
2019-05-09 |
Juno Therapeutics, Inc. |
Combination of a cell therapy and a gamma secretase inhibitor
|
|
KR20200079312A
(ko)
|
2017-11-06 |
2020-07-02 |
에디타스 메디신, 인코포레이티드 |
면역요법을 위한 t 세포 내 cblb의 crispr-cas9 편집 방법, 조성물 및 성분
|
|
CN111556789A
(zh)
|
2017-11-10 |
2020-08-18 |
朱诺治疗学股份有限公司 |
封闭系统低温器皿
|
|
EP3716980A1
(en)
|
2017-12-01 |
2020-10-07 |
Juno Therapeutics, Inc. |
Methods for dosing and for modulation of genetically engineered cells
|
|
KR102853341B1
(ko)
|
2017-12-08 |
2025-09-02 |
주노 쎄러퓨티크스 인코퍼레이티드 |
조작된 t 세포의 조성물을 제조하는 방법
|
|
CA3084446A1
(en)
|
2017-12-08 |
2019-06-13 |
Juno Therapeutics, Inc. |
Phenotypic markers for cell therapy and related methods
|
|
SG11202005228YA
(en)
|
2017-12-08 |
2020-07-29 |
Juno Therapeutics Inc |
Serum-free media formulation for culturing cells and methods of use thereof
|
|
CN112204048A
(zh)
|
2017-12-15 |
2021-01-08 |
朱诺治疗学股份有限公司 |
抗cct5结合分子及其使用方法
|
|
AU2019205273B2
(en)
|
2018-01-03 |
2024-04-04 |
Alpine Immune Sciences, Inc. |
Multi-domain immunomodulatory proteins and methods of use thereof
|
|
WO2019134036A1
(en)
|
2018-01-03 |
2019-07-11 |
Qu Biologics Inc. |
Innate targeting of adoptive cellular therapies
|
|
WO2019139972A1
(en)
|
2018-01-09 |
2019-07-18 |
Board Of Regents, The University Of Texas System |
T cell receptors for immunotherapy
|
|
BR112020014913A2
(pt)
|
2018-01-22 |
2020-12-08 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Métodos para uso de células t car
|
|
JP2021511802A
(ja)
|
2018-01-31 |
2021-05-13 |
ジュノー セラピューティクス インコーポレイテッド |
複製可能ウイルスの存在または非存在を評価するための方法および試薬
|
|
CN111971059A
(zh)
|
2018-01-31 |
2020-11-20 |
细胞基因公司 |
使用过继细胞疗法和检查点抑制剂的组合疗法
|
|
SG11202007426XA
(en)
|
2018-02-06 |
2020-09-29 |
Seattle Childrens Hospital Dba Seattle Childrens Res Inst |
Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors
|
|
SG11202007156QA
(en)
|
2018-02-09 |
2020-08-28 |
Nat Univ Singapore |
Activating chimeric receptors and uses thereof in natural killer cell immunotherapy
|
|
EP3752601A4
(en)
|
2018-02-15 |
2022-03-23 |
Memorial Sloan-Kettering Cancer Center |
FOXP3-TARGETING AGENT COMPOSITIONS AND METHODS OF USE FOR ADOPTIVE CELL THERAPY
|
|
CN111918661A
(zh)
|
2018-02-21 |
2020-11-10 |
得克萨斯大学体系董事会 |
用于活化和扩增自然杀伤细胞的方法及其用途
|
|
CA3091674A1
(en)
|
2018-02-23 |
2019-08-29 |
Endocyte, Inc. |
Sequencing method for car t cell therapy
|
|
IL276831B2
(en)
|
2018-03-02 |
2025-04-01 |
Allogene Therapeutics Inc |
Chimeric inducible cytokine receptors
|
|
US20210046159A1
(en)
|
2018-03-09 |
2021-02-18 |
Ospedale San Raffaele S.R.L. |
Il-1 antagonist and toxicity induced by cell therapy
|
|
SG11202008976YA
(en)
|
2018-04-02 |
2020-10-29 |
Nat Univ Singapore |
Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells
|
|
JP7589047B2
(ja)
|
2018-04-05 |
2024-11-25 |
ジュノー セラピューティクス インコーポレイテッド |
組換え受容体を発現する細胞の作製方法および関連組成物
|
|
KR102764123B1
(ko)
|
2018-04-05 |
2025-02-05 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Τ 세포 수용체 및 이를 발현하는 조작된 세포
|
|
CN120442670A
(zh)
*
|
2018-04-26 |
2025-08-08 |
贝勒医学院 |
用于选择性靶向活化的致病性t细胞和nk细胞的自体/同种异体免疫防御受体
|
|
BR112020022185A2
(pt)
|
2018-05-03 |
2021-02-02 |
Juno Therapeutics Inc |
terapia de combinação de uma terapia de células t do receptor de antígeno quimérico (car) e um inibidor de quinase
|
|
EP4431943A3
(en)
*
|
2018-05-11 |
2024-10-23 |
Memorial Sloan-Kettering Cancer Center |
Methods for identifying antigen-specific t cell receptors
|
|
SG11202011080QA
(en)
|
2018-05-11 |
2020-12-30 |
Crispr Therapeutics Ag |
Methods and compositions for treating cancer
|
|
EP3806961A4
(en)
|
2018-05-11 |
2022-10-19 |
Memorial Sloan Kettering Cancer Center |
T LYMPHOCYTE RECEPTORS TARGETING PIK3CA MUTATIONS AND THEIR USES
|
|
TWI890660B
(zh)
|
2018-06-13 |
2025-07-21 |
瑞士商諾華公司 |
Bcma 嵌合抗原受體及其用途
|
|
US12065476B2
(en)
|
2018-06-15 |
2024-08-20 |
Alpine Immune Sciences, Inc. |
PD-1 variant immunomodulatory proteins and uses thereof
|
|
KR20210059715A
(ko)
|
2018-08-09 |
2021-05-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
통합된 핵산 평가 방법
|
|
SG11202101204TA
(en)
|
2018-08-09 |
2021-03-30 |
Juno Therapeutics Inc |
Processes for generating engineered cells and compositions thereof
|
|
CA3110089A1
(en)
|
2018-08-28 |
2020-03-05 |
Fred Hutchinson Cancer Research Center |
Methods and compositions for adoptive t cell therapy incorporating induced notch signaling
|
|
KR102839381B1
(ko)
|
2018-08-29 |
2025-07-28 |
내셔널 유니버시티 오브 싱가포르 |
유전적으로 변형된 면역 세포의 생존 및 확장을 특이적으로 자극하는 방법
|
|
EA202190693A1
(ru)
|
2018-09-11 |
2021-07-27 |
Джуно Терапьютикс, Инк. |
Способы анализа масс-спектрометрии композиций модифицированных клеток
|
|
AU2019370705A1
(en)
|
2018-10-31 |
2021-05-27 |
Juno Therapeutics Gmbh |
Methods for selection and stimulation of cells and apparatus for same
|
|
CA3117419A1
(en)
|
2018-11-01 |
2020-05-07 |
Juno Therapeutics, Inc. |
Methods for treatment using chimeric antigen receptors specific for b-cell maturation antigen
|
|
EP3877054B1
(en)
|
2018-11-06 |
2023-11-01 |
Juno Therapeutics, Inc. |
Process for producing genetically engineered t cells
|
|
AU2019377854A1
(en)
|
2018-11-08 |
2021-05-27 |
Juno Therapeutics, Inc. |
Methods and combinations for treatment and T cell modulation
|
|
JP7179986B2
(ja)
|
2018-11-14 |
2022-11-29 |
グリーン クロス ラボ セル コーポレーション |
形質転換されたt細胞を用いた臍帯血由来のナチュラルキラー細胞の培養方法
|
|
WO2020101361A1
(ko)
*
|
2018-11-14 |
2020-05-22 |
주식회사 녹십자랩셀 |
형질전환된 t세포를 이용한 제대혈 유래 자연살해세포의 배양방법
|
|
KR20210104713A
(ko)
|
2018-11-16 |
2021-08-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
B 세포 악성 종양 치료를 위한 조작된 t 세포 투약 방법
|
|
WO2020106621A1
(en)
|
2018-11-19 |
2020-05-28 |
Board Of Regents, The University Of Texas System |
A modular, polycistronic vector for car and tcr transduction
|
|
BR112021010297A2
(pt)
|
2018-11-28 |
2021-08-24 |
Board Of Regents, The University Of Texas System |
Edição de genomas multiplexadores de células imunes para aumentar a funcionalidade e resistência ao ambiente supressivo
|
|
MX2021006393A
(es)
|
2018-11-29 |
2021-10-13 |
Univ Texas |
Metodos para expansion ex vivo de celulas exterminadoras naturales y uso de las mismas.
|
|
WO2020113194A2
(en)
|
2018-11-30 |
2020-06-04 |
Juno Therapeutics, Inc. |
Methods for treatment using adoptive cell therapy
|
|
EP3886894B1
(en)
|
2018-11-30 |
2024-03-13 |
Juno Therapeutics, Inc. |
Methods for dosing and treatment of b cell malignancies in adoptive cell therapy
|
|
CN111254119B
(zh)
*
|
2018-12-03 |
2022-11-11 |
广州保瑞医疗技术有限公司 |
具有提高免疫应答功效的t细胞及其制备方法和应用
|
|
CN111249307A
(zh)
*
|
2018-12-03 |
2020-06-09 |
广州保瑞医疗技术有限公司 |
具有提高免疫应答功效的t细胞及其制备方法和应用
|
|
WO2020160050A1
(en)
|
2019-01-29 |
2020-08-06 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for receptor tyrosine kinase like orphan receptor 1 (ror1)
|
|
US12043655B2
(en)
|
2019-03-01 |
2024-07-23 |
Allogene Therapeutics, Inc. |
Constitutively active chimeric cytokine receptors
|
|
CN113518785A
(zh)
|
2019-03-01 |
2021-10-19 |
艾洛基治疗公司 |
携带pd-1胞外域的嵌合细胞因子受体
|
|
AU2020232691B2
(en)
|
2019-03-05 |
2023-06-29 |
Nkarta, Inc. |
CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
|
|
JP2022531185A
(ja)
|
2019-04-30 |
2022-07-06 |
クリスパー セラピューティクス アクチェンゲゼルシャフト |
遺伝子改変t細胞を標的化するcd19を使用するb細胞悪性病変の同種細胞療法
|
|
JP7711945B2
(ja)
|
2019-04-30 |
2025-07-23 |
センティ バイオサイエンシズ インコーポレイテッド |
キメラ受容体及びその使用方法
|
|
MX2021013223A
(es)
|
2019-05-01 |
2022-02-17 |
Juno Therapeutics Inc |
Celulas que expresan un receptor quimerico de un locus cd247 modificado, polinucleotidos relacionados y metodos.
|
|
CN114025788A
(zh)
|
2019-05-01 |
2022-02-08 |
朱诺治疗学股份有限公司 |
从经修饰的tgfbr2基因座表达重组受体的细胞、相关多核苷酸和方法
|
|
CA3139965A1
(en)
|
2019-06-07 |
2020-12-10 |
Ivie AIFUWA |
Automated t cell culture
|
|
KR20220034782A
(ko)
|
2019-06-12 |
2022-03-18 |
주노 쎄러퓨티크스 인코퍼레이티드 |
세포 매개 세포 독성 요법 및 친생존 bcl2 패밀리 단백질 억제제의 병용 요법
|
|
EP3990491A1
(en)
|
2019-06-26 |
2022-05-04 |
Massachusetts Institute of Technology |
Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
|
|
EP3998083A4
(en)
|
2019-07-12 |
2023-08-23 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-mutation type fgfr3 antibody and use therefor
|
|
AU2020315796A1
(en)
*
|
2019-07-19 |
2022-02-24 |
Memorial Hospital For Cancer And Allied Diseases |
Fusion polypeptide for immunotherapy
|
|
AU2020318781A1
(en)
|
2019-07-23 |
2022-02-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Immune cells defective for SUV39H1
|
|
US20220298222A1
(en)
|
2019-08-22 |
2022-09-22 |
Juno Therapeutics, Inc. |
Combination therapy of a t cell therapy and an enhancer of zeste homolog 2 (ezh2) inhibitor and related methods
|
|
CN114600172A
(zh)
|
2019-08-30 |
2022-06-07 |
朱诺治疗学股份有限公司 |
用于将细胞分类的机器学习方法
|
|
BR112022003790A2
(pt)
|
2019-09-02 |
2022-05-31 |
Inst Nat Sante Rech Med |
Método para selecionar um peptídeo neoantigênico tumoral, peptídeos neoantigênicos tumorais, peptídeo neoantigênico tumoral isolado, população de células dendríticas autólogas, vacina ou composição imunogênica, anticorpos, método de produção de um anticorpo, receptor de células t, polinucleotídeo, vetor, célula imune, célula t, peptídeo neoantigênico e população de células imunes
|
|
WO2021061648A1
(en)
|
2019-09-23 |
2021-04-01 |
Massachusetts Institute Of Technology |
Methods and compositions for stimulation of endogenous t cell responses
|
|
US20220401539A1
(en)
|
2019-10-22 |
2022-12-22 |
Institut Curie |
Immunotherapy Targeting Tumor Neoantigenic Peptides
|
|
AU2020377043A1
(en)
|
2019-10-30 |
2022-06-02 |
Juno Therapeutics Gmbh |
Cell selection and/or stimulation devices and methods of use
|
|
JP2022554353A
(ja)
|
2019-11-07 |
2022-12-28 |
ジュノー セラピューティクス インコーポレイテッド |
T細胞療法と(s)-3-[4-(4-モルホリン-4-イルメチル-ベンジルオキシ)-1-オキソ-1,3-ジヒドロ-イソインドール-2-イル]-ピペリジン-2,6-ジオンとの併用
|
|
AR120566A1
(es)
|
2019-11-26 |
2022-02-23 |
Novartis Ag |
Receptores de antígeno quiméricos y sus usos
|
|
BR112022009679A2
(pt)
|
2019-11-26 |
2022-08-09 |
Novartis Ag |
Receptores de antígeno quimérico cd19 e cd22 e usos dos mesmos
|
|
JP2023504740A
(ja)
|
2019-12-06 |
2023-02-06 |
ジュノー セラピューティクス インコーポレイテッド |
Bcma標的結合ドメインに対する抗イディオタイプ抗体ならびに関連する組成物および方法
|
|
WO2021113770A1
(en)
|
2019-12-06 |
2021-06-10 |
Juno Therapeutics, Inc. |
Methods related to toxicity and response associated with cell therapy for treating b cell malignancies
|
|
US20230192869A1
(en)
|
2019-12-06 |
2023-06-22 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to gprc5d-targeted binding domains and related compositions and methods
|
|
MX2022009041A
(es)
|
2020-01-24 |
2022-10-07 |
Juno Therapeutics Inc |
Metodos de dosificacion y tratamiento de linfoma folicular y linfoma de zona marginal en terapia celular adoptiva.
|
|
EP4097218A1
(en)
|
2020-01-28 |
2022-12-07 |
Juno Therapeutics, Inc. |
Methods for t cell transduction
|
|
CN115768443A
(zh)
|
2020-02-12 |
2023-03-07 |
朱诺治疗学股份有限公司 |
Cd19定向嵌合抗原受体t细胞组合物和方法及其用途
|
|
BR112022015968A2
(pt)
|
2020-02-12 |
2022-10-11 |
Juno Therapeutics Inc |
Composições de células t do receptor de antígeno quimérico direcionado a bcma e métodos e usos das mesmas
|
|
CA3168337A1
(en)
|
2020-02-17 |
2021-08-26 |
Marie-Andree Forget |
Methods for expansion of tumor infiltrating lymphocytes and use thereof
|
|
EP4110805A1
(en)
|
2020-02-24 |
2023-01-04 |
Allogene Therapeutics, Inc. |
Bcma car-t cells with enhanced activities
|
|
IL296242A
(en)
|
2020-03-10 |
2022-11-01 |
Massachusetts Inst Technology |
Methods for producing engineered memory-like nk cells and preparations containing them
|
|
CN113402612A
(zh)
|
2020-03-17 |
2021-09-17 |
西比曼生物科技(香港)有限公司 |
靶向cd19和cd20的联合嵌合抗原受体及其应用
|
|
WO2021207171A1
(en)
*
|
2020-04-06 |
2021-10-14 |
St. Jude Children's Research Hospital, Inc. |
B7-h3 chimeric antigen receptors
|
|
WO2021207689A2
(en)
|
2020-04-10 |
2021-10-14 |
Juno Therapeutics, Inc. |
Methods and uses related to cell therapy engineered with a chimeric antigen receptor targeting b-cell maturation antigen
|
|
US20210340524A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
|
WO2021221782A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Chimeric antigen receptor-targeting ligands and uses thereof
|
|
WO2021228999A1
(en)
|
2020-05-12 |
2021-11-18 |
Institut Curie |
Neoantigenic epitopes associated with sf3b1 mutations
|
|
KR20230022868A
(ko)
|
2020-05-13 |
2023-02-16 |
주노 쎄러퓨티크스 인코퍼레이티드 |
재조합 수용체를 발현하는 공여자-배치 세포의 제조 방법
|
|
KR20230024283A
(ko)
|
2020-05-13 |
2023-02-20 |
주노 쎄러퓨티크스 인코퍼레이티드 |
임상 반응과 관련된 특징을 식별하는 방법 및 이의 용도
|
|
CN115803084A
(zh)
|
2020-05-21 |
2023-03-14 |
得克萨斯大学体系董事会 |
具有vgll1特异性的t细胞受体和其用途
|
|
US20240216508A1
(en)
|
2020-06-26 |
2024-07-04 |
Juno Therapeutics Gmbh |
Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
|
|
CA3190266A1
(en)
|
2020-07-30 |
2022-02-03 |
Institut Curie |
Immune cells defective for socs1
|
|
WO2022029660A1
(en)
|
2020-08-05 |
2022-02-10 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to ror1-targeted binding domains and related compositions and methods
|
|
KR20230054391A
(ko)
|
2020-08-21 |
2023-04-24 |
12343096 캐나다 인코포레이티드 |
모듈러 조립 수용체 및 그의 용도
|
|
MX2023004598A
(es)
|
2020-10-23 |
2023-06-29 |
Asher Biotherapeutics Inc |
Fusiones con moléculas de unión al antígeno cd8 para modular la función de las células inmunitarias.
|
|
US20230051406A1
(en)
|
2020-11-13 |
2023-02-16 |
Catamaran Bio, Inc. |
Genetically modified natural killer cells and methods of use thereof
|
|
TW202237827A
(zh)
|
2020-12-03 |
2022-10-01 |
美商世紀治療股份有限公司 |
經基因工程改造之細胞及其用途
|
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
|
WO2022133030A1
(en)
|
2020-12-16 |
2022-06-23 |
Juno Therapeutics, Inc. |
Combination therapy of a cell therapy and a bcl2 inhibitor
|
|
TW202241479A
(zh)
|
2020-12-30 |
2022-11-01 |
美商安迅生物製藥公司 |
遞送外來抗原之溶瘤病毒及表現靶向外來抗原之嵌合受體之經工程化免疫細胞之組合療法
|
|
US12234473B2
(en)
|
2020-12-31 |
2025-02-25 |
Immatics US, Inc. |
CD8 polypeptides, compositions, and methods of using thereof
|
|
KR20230151513A
(ko)
|
2021-01-11 |
2023-11-01 |
사나 바이오테크놀로지, 인크. |
Cd8 표적 바이러스 벡터의 용도
|
|
AR124681A1
(es)
|
2021-01-20 |
2023-04-26 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
|
WO2022187406A1
(en)
|
2021-03-03 |
2022-09-09 |
Juno Therapeutics, Inc. |
Combination of a t cell therapy and a dgk inhibitor
|
|
MX2023010641A
(es)
|
2021-03-11 |
2024-02-07 |
Mnemo Therapeutics |
Peptidos neoantigénicos tumorales y usos de los mismos.
|
|
KR20230172630A
(ko)
|
2021-03-11 |
2023-12-22 |
므네모 테라퓨틱스 |
종양 네오 항원성 펩타이드
|
|
KR20240006721A
(ko)
|
2021-03-11 |
2024-01-15 |
엥스띠뛰 퀴리 |
막 형질 전환 네오 안티젠 펩타이드
|
|
JP2024511418A
(ja)
|
2021-03-22 |
2024-03-13 |
ジュノー セラピューティクス インコーポレイテッド |
治療用細胞組成物の効力を決定する方法
|
|
AU2022244229A1
(en)
|
2021-03-22 |
2023-09-14 |
Juno Therapeutics, Inc. |
Method to assess potency of viral vector particles
|
|
US20240181052A1
(en)
|
2021-03-29 |
2024-06-06 |
Juno Therapeutics, Inc. |
Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
|
|
JP2024513054A
(ja)
|
2021-03-29 |
2024-03-21 |
ジュノー セラピューティクス インコーポレイテッド |
リンパ腫の治療のためのcar t細胞療法および免疫調節化合物の組合せ
|
|
JP2024514942A
(ja)
|
2021-04-22 |
2024-04-03 |
ベイラー カレッジ オブ メディスン |
殺夾雑活性を低下させた免疫細胞を工学的に作製する方法
|
|
CN117916256A
(zh)
|
2021-05-06 |
2024-04-19 |
朱诺治疗学有限公司 |
用于刺激和转导t细胞的方法
|
|
WO2023015217A1
(en)
|
2021-08-04 |
2023-02-09 |
Sana Biotechnology, Inc. |
Use of cd4-targeted viral vectors
|
|
IL310550A
(en)
|
2021-08-04 |
2024-03-01 |
Univ Colorado Regents |
LAT-activating chimeric antigen receptor T cells and methods of using them
|
|
WO2023081715A1
(en)
|
2021-11-03 |
2023-05-11 |
Viracta Therapeutics, Inc. |
Combination of car t-cell therapy with btk inhibitors and methods of use thereof
|
|
US20250354167A1
(en)
|
2021-12-09 |
2025-11-20 |
Zygosity Limited |
Vector
|
|
US20250059239A1
(en)
|
2021-12-17 |
2025-02-20 |
Sana Biotechnology, Inc. |
Modified paramyxoviridae fusion glycoproteins
|
|
EP4448775A1
(en)
|
2021-12-17 |
2024-10-23 |
Sana Biotechnology, Inc. |
Modified paramyxoviridae attachment glycoproteins
|
|
EP4456910A1
(en)
|
2021-12-28 |
2024-11-06 |
Mnemo Therapeutics |
Immune cells with inactivated suv39h1 and modified tcr
|
|
JP2025504882A
(ja)
|
2022-01-21 |
2025-02-19 |
ムネモ・セラピューティクス |
Rnaによるsuv39h1発現の調節
|
|
JP2025504002A
(ja)
|
2022-01-28 |
2025-02-06 |
ジュノー セラピューティクス インコーポレイテッド |
細胞組成物を製造する方法
|
|
EP4472646A1
(en)
|
2022-02-01 |
2024-12-11 |
Sana Biotechnology, Inc. |
Cd3-targeted lentiviral vectors and uses thereof
|
|
AU2023236826A1
(en)
|
2022-03-18 |
2024-09-26 |
The Regents Of The University Of Colorado, A Body Corporate |
Genetically engineered t-cell co-receptors and methods of use thereof
|
|
US20250302930A1
(en)
|
2022-03-24 |
2025-10-02 |
Institut Curie |
Immunotherapy targeting tumor transposable element derived neoantigenic peptides in glioblastoma
|
|
WO2023193015A1
(en)
|
2022-04-01 |
2023-10-05 |
Sana Biotechnology, Inc. |
Cytokine receptor agonist and viral vector combination therapies
|
|
WO2023196921A1
(en)
|
2022-04-06 |
2023-10-12 |
The Regents Of The University Of Colorado, A Body Corporate |
Granzyme expressing t cells and methods of use
|
|
US20250304913A1
(en)
|
2022-04-06 |
2025-10-02 |
The Regents Of The University Of Colorado, A Body Corporate |
Chimeric antigen receptor t cells and methods of use thereof
|
|
EP4514382A1
(en)
|
2022-04-28 |
2025-03-05 |
Musc Foundation for Research Development |
Chimeric antigen receptor modified regulatory t cells for treating cancer
|
|
WO2023213969A1
(en)
|
2022-05-05 |
2023-11-09 |
Juno Therapeutics Gmbh |
Viral-binding protein and related reagents, articles, and methods of use
|
|
US20250302954A1
(en)
|
2022-05-11 |
2025-10-02 |
Celgene Corporation |
Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
|
|
EP4279085A1
(en)
|
2022-05-20 |
2023-11-22 |
Mnemo Therapeutics |
Compositions and methods for treating a refractory or relapsed cancer or a chronic infectious disease
|
|
WO2023230581A1
(en)
|
2022-05-25 |
2023-11-30 |
Celgene Corporation |
Methods of manufacturing t cell therapies
|
|
KR20250029137A
(ko)
|
2022-06-22 |
2025-03-04 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Cd19-표적화된 car t 세포의 2차 요법을 위한 치료 방법
|
|
EP4547230A1
(en)
|
2022-06-29 |
2025-05-07 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids
|
|
AU2023329484A1
(en)
|
2022-08-26 |
2025-02-20 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for delta-like ligand 3 (dll3)
|
|
JP2025531850A
(ja)
|
2022-09-08 |
2025-09-25 |
ジュノー セラピューティクス インコーポレイテッド |
T細胞療法および継続的または間欠的dgk阻害剤投薬の組合せ
|
|
WO2024062138A1
(en)
|
2022-09-23 |
2024-03-28 |
Mnemo Therapeutics |
Immune cells comprising a modified suv39h1 gene
|
|
WO2024081820A1
(en)
|
2022-10-13 |
2024-04-18 |
Sana Biotechnology, Inc. |
Viral particles targeting hematopoietic stem cells
|
|
WO2024100604A1
(en)
|
2022-11-09 |
2024-05-16 |
Juno Therapeutics Gmbh |
Methods for manufacturing engineered immune cells
|
|
KR20250121074A
(ko)
|
2022-12-09 |
2025-08-11 |
주노 쎄러퓨티크스 인코퍼레이티드 |
홀로그래픽 이미징을 사용하여 세포 표현형을 예측하기 위한 기계 학습 방법
|
|
CN121002052A
(zh)
|
2023-02-03 |
2025-11-21 |
C3S2 有限公司 |
用于非病毒生产工程化免疫细胞的方法
|
|
TW202502363A
(zh)
|
2023-02-28 |
2025-01-16 |
美商奇諾治療有限公司 |
用於治療全身性自體免疫疾病之細胞療法
|
|
WO2024220588A1
(en)
|
2023-04-18 |
2024-10-24 |
Juno Therapeutics, Inc. |
Cytotoxicity assay for assessing potency of therapeutic cell compositions
|
|
WO2024220574A1
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Universal protein g fusogens and adapter systems thereof and related lipid particles and uses
|
|
WO2024220560A1
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Engineered protein g fusogens and related lipid particles and methods thereof
|
|
WO2024220598A2
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Lentiviral vectors with two or more genomes
|
|
WO2024226858A1
(en)
|
2023-04-26 |
2024-10-31 |
Juno Therapeutics, Inc. |
Methods for viral vector manufacturing
|
|
WO2024243365A2
(en)
|
2023-05-23 |
2024-11-28 |
Juno Therapeutics, Inc. |
Activation markers of t cells and method for assessing t cell activation
|
|
WO2025054202A1
(en)
|
2023-09-05 |
2025-03-13 |
Sana Biotechnology, Inc. |
Method of screening a sample comprising a transgene with a unique barcode
|
|
EP4520334A1
(en)
|
2023-09-07 |
2025-03-12 |
Mnemo Therapeutics |
Methods and compositions for improving immune response
|
|
WO2025052001A1
(en)
|
2023-09-07 |
2025-03-13 |
Mnemo Therapeutics |
Methods and compositions for improving immune response
|
|
WO2025059162A1
(en)
|
2023-09-11 |
2025-03-20 |
Dana-Farber Cancer Institute, Inc. |
Car-engager containing il-2 variants to enhance the functionality of car t cells
|
|
WO2025082603A1
(en)
|
2023-10-18 |
2025-04-24 |
Institut Curie |
Engineered immune cells overexpressing cd74 molecule
|
|
WO2025096975A1
(en)
|
2023-11-02 |
2025-05-08 |
The Regents Of The University Of Colorado, A Body Corporate |
Compositions and methods of enhancing immune cell therapies by runx2 modulation
|
|
WO2025147545A1
(en)
|
2024-01-03 |
2025-07-10 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids and related methods and uses
|
|
WO2025151838A1
(en)
|
2024-01-12 |
2025-07-17 |
Sana Biotechnology, Inc. |
Safety switches to control in vitro and in vivo proliferation of cell therapy products
|
|
WO2025163107A1
(en)
|
2024-02-01 |
2025-08-07 |
Institut Gustave Roussy |
Immune cells defective for znf217 and uses thereof
|
|
WO2025184421A1
(en)
|
2024-02-28 |
2025-09-04 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors and antibodies specific for delta-like ligand 3 (dll3) and related methods
|
|
US20250345431A1
(en)
|
2024-05-10 |
2025-11-13 |
Juno Therapeutics, Inc. |
Genetically engineered t cells expressing a cd19 chimeric antigen receptor (car) and uses thereof for allogeneic cell therapy
|
|
WO2025233867A1
(en)
|
2024-05-10 |
2025-11-13 |
Adaptam Therapeutics, S.L. |
Anti-siglec-9 antibodies and uses thereof
|