MA50855A - Procédé de génération de compositions thérapeutiques de cellules modifiées - Google Patents
Procédé de génération de compositions thérapeutiques de cellules modifiéesInfo
- Publication number
- MA50855A MA50855A MA050855A MA50855A MA50855A MA 50855 A MA50855 A MA 50855A MA 050855 A MA050855 A MA 050855A MA 50855 A MA50855 A MA 50855A MA 50855 A MA50855 A MA 50855A
- Authority
- MA
- Morocco
- Prior art keywords
- therapeutic compositions
- modified cells
- generating therapeutic
- generating
- cells
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/463—Cellular immunotherapy characterised by recombinant expression
- A61K39/4631—Chimeric Antigen Receptors [CAR]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464402—Receptors, cell surface antigens or cell surface determinants
- A61K39/464411—Immunoglobulin superfamily
- A61K39/464412—CD19 or B4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2302—Interleukin-2 (IL-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2307—Interleukin-7 (IL-7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2315—Interleukin-15 (IL-15)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762580409P | 2017-11-01 | 2017-11-01 | |
US201762596771P | 2017-12-08 | 2017-12-08 | |
US201862721603P | 2018-08-22 | 2018-08-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA50855A true MA50855A (fr) | 2020-09-09 |
Family
ID=64362686
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA050855A MA50855A (fr) | 2017-11-01 | 2018-10-31 | Procédé de génération de compositions thérapeutiques de cellules modifiées |
Country Status (13)
Country | Link |
---|---|
US (1) | US20200354677A1 (fr) |
EP (1) | EP3704230A1 (fr) |
JP (2) | JP7357626B2 (fr) |
KR (1) | KR20200099132A (fr) |
CN (1) | CN111542596A (fr) |
AU (1) | AU2018360599A1 (fr) |
BR (1) | BR112020008340A2 (fr) |
CA (1) | CA3084514A1 (fr) |
IL (1) | IL274293A (fr) |
MA (1) | MA50855A (fr) |
MX (1) | MX2020004240A (fr) |
SG (1) | SG11202003688PA (fr) |
WO (1) | WO2019089855A1 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2763795C2 (ru) | 2014-04-23 | 2022-01-11 | Джуно Терапьютикс, Инк. | Способы выделения, культивирования и генетической инженерии популяций клеток иммунной системы для адоптивной терапии |
EP3880238A1 (fr) | 2018-11-16 | 2021-09-22 | Juno Therapeutics, Inc. | Méthodes de posologie pour cellules t modifiées pour le traitement de cancers à cellules b |
JP2022513689A (ja) | 2018-11-30 | 2022-02-09 | ジュノー セラピューティクス インコーポレイテッド | 養子細胞療法におけるb細胞悪性腫瘍の投与および処置のための方法 |
KR20210117260A (ko) | 2018-11-30 | 2021-09-28 | 주노 쎄러퓨티크스 인코퍼레이티드 | 입양 세포 요법을 사용한 치료방법 |
CA3132509A1 (fr) * | 2019-04-26 | 2020-10-29 | Allogene Therapeutics, Inc. | Procedes de fabrication de cellules car-t allogeniques |
EP4055383A1 (fr) | 2019-11-05 | 2022-09-14 | Juno Therapeutics, Inc. | Procédés de détermination d'attributs de compositions de cellules t thérapeutiques |
WO2021113770A1 (fr) | 2019-12-06 | 2021-06-10 | Juno Therapeutics, Inc. | Procédés liés à la toxicité et à la réponse associées à une thérapie cellulaire pour le traitement de tumeurs malignes des lymphocytes b |
IL294724A (en) | 2020-01-24 | 2022-09-01 | Juno Therapeutics Inc | Methods for dosing and treatment of follicular lymphoma and marginal zone lymphoma in stress cell therapy |
EP4150640A1 (fr) | 2020-05-13 | 2023-03-22 | Juno Therapeutics, Inc. | Procédés d'identification de caractéristiques associées à une réponse clinique et leurs utilisations |
US20240168012A1 (en) | 2021-03-22 | 2024-05-23 | Juno Therapeutics, Inc. | Methods of determining potency of a therapeutic cell composition |
TWI828009B (zh) * | 2021-11-19 | 2024-01-01 | 財團法人工業技術研究院 | 免標記式細胞活性檢測的方法及訓練人工智慧執行免標記式細胞活性檢測的方法 |
WO2023230548A1 (fr) | 2022-05-25 | 2023-11-30 | Celgene Corporation | Procédé de prédiction d'une réponse à une thérapie par lymphocyte t |
WO2023250400A1 (fr) | 2022-06-22 | 2023-12-28 | Juno Therapeutics, Inc. | Méthodes de traitement pour thérapie de deuxième ligne par cellules car-t ciblées par cd19 |
WO2024124132A1 (fr) | 2022-12-09 | 2024-06-13 | Juno Therapeutics, Inc. | Procédés d'apprentissage automatique pour prédire un phénotype cellulaire au moyen d'une imagerie holographique |
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RU2763795C2 (ru) | 2014-04-23 | 2022-01-11 | Джуно Терапьютикс, Инк. | Способы выделения, культивирования и генетической инженерии популяций клеток иммунной системы для адоптивной терапии |
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HUE057777T2 (hu) | 2014-12-05 | 2022-06-28 | Memorial Sloan Kettering Cancer Center | Kiméra antigén receptorok, amelyek G-fehérje-kapcsolt receptort céloznak meg, és a receptorok alkalmazásai |
KR20230159637A (ko) | 2014-12-05 | 2023-11-21 | 메모리얼 슬로안 케터링 캔서 센터 | G-단백질 커플화 수용체를 표적화하는 항체 및 이의 사용 방법 |
WO2017015490A1 (fr) | 2015-07-21 | 2017-01-26 | City Of Hope | Lymphocytes t pour l'expression de récepteurs d'antigènes chimères |
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CN108779242B (zh) | 2016-03-17 | 2021-06-11 | 默克专利股份公司 | 纯化泊洛沙姆的方法 |
CA3015369A1 (fr) | 2016-03-18 | 2017-09-21 | Oliver Press | Compositions et methodes pour immunotherapie anti-cd20 |
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MA54103A (fr) * | 2017-04-14 | 2021-09-15 | Juno Therapeutics Inc | Procédés d'évaluation de la glycosylation de surface cellulaire |
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-
2018
- 2018-10-31 MA MA050855A patent/MA50855A/fr unknown
- 2018-10-31 US US16/760,240 patent/US20200354677A1/en active Pending
- 2018-10-31 AU AU2018360599A patent/AU2018360599A1/en active Pending
- 2018-10-31 KR KR1020207015597A patent/KR20200099132A/ko unknown
- 2018-10-31 BR BR112020008340-2A patent/BR112020008340A2/pt unknown
- 2018-10-31 EP EP18804808.6A patent/EP3704230A1/fr active Pending
- 2018-10-31 WO PCT/US2018/058590 patent/WO2019089855A1/fr unknown
- 2018-10-31 SG SG11202003688PA patent/SG11202003688PA/en unknown
- 2018-10-31 MX MX2020004240A patent/MX2020004240A/es unknown
- 2018-10-31 JP JP2020543731A patent/JP7357626B2/ja active Active
- 2018-10-31 CA CA3084514A patent/CA3084514A1/fr active Pending
- 2018-10-31 CN CN201880084155.4A patent/CN111542596A/zh active Pending
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2020
- 2020-04-27 IL IL274293A patent/IL274293A/en unknown
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2023
- 2023-09-26 JP JP2023163684A patent/JP2023182652A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3704230A1 (fr) | 2020-09-09 |
JP2023182652A (ja) | 2023-12-26 |
MX2020004240A (es) | 2020-09-25 |
KR20200099132A (ko) | 2020-08-21 |
CN111542596A (zh) | 2020-08-14 |
BR112020008340A2 (pt) | 2020-11-17 |
WO2019089855A1 (fr) | 2019-05-09 |
JP2021501604A (ja) | 2021-01-21 |
CA3084514A1 (fr) | 2019-05-09 |
IL274293A (en) | 2020-06-30 |
SG11202003688PA (en) | 2020-05-28 |
JP7357626B2 (ja) | 2023-10-06 |
US20200354677A1 (en) | 2020-11-12 |
AU2018360599A1 (en) | 2020-05-07 |
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