US8765687B2
(en)
|
2005-10-17 |
2014-07-01 |
Sloan Kettering Institute For Cancer Research |
WT1 HLA class II-binding peptides and compositions and methods comprising same
|
CN101330830B
(en)
|
2005-10-18 |
2016-01-20 |
国家犹太健康中心 |
Condition immortalization long-term stem cells and preparation and use the method for described cell
|
ES2591029T3
(en)
|
2006-04-10 |
2016-11-24 |
Sloan Kettering Institute For Cancer Research |
WT-1 immunogenic peptides and methods for use
|
IL287311B1
(en)
|
2008-05-16 |
2024-02-01 |
Taiga Biotechnologies Inc |
Antibodies and processes for preparing the same
|
IL301475A
(en)
|
2008-08-28 |
2023-05-01 |
Taiga Biotechnologies Inc |
In Vitro Methods for Increasing Viability of Immune-Cells
|
CA2861206C
(en)
|
2012-01-13 |
2021-07-06 |
Richard J. O'reilly |
Immunogenic wt-1 peptides and methods of use thereof
|
CA2879667C
(en)
|
2012-07-20 |
2021-11-16 |
Taiga Biotechnologies, Inc. |
Enhanced reconstitution and autoreconstitution of the hematopoietic compartment comprising a myc polypeptide
|
PT2945647T
(en)
|
2013-01-15 |
2020-11-26 |
Memorial Sloan Kettering Cancer Center |
Immunogenic wt-1 peptides and methods of use thereof
|
US10815273B2
(en)
|
2013-01-15 |
2020-10-27 |
Memorial Sloan Kettering Cancer Center |
Immunogenic WT-1 peptides and methods of use thereof
|
US10272115B2
(en)
|
2013-03-11 |
2019-04-30 |
Taiga Biotechnologies, Inc. |
Production and use of red blood cells
|
MX2016006625A
(en)
*
|
2013-11-22 |
2016-12-02 |
Univ Illinois |
Engineered high-affinity human t cell receptors.
|
US10801070B2
(en)
|
2013-11-25 |
2020-10-13 |
The Broad Institute, Inc. |
Compositions and methods for diagnosing, evaluating and treating cancer
|
US11725237B2
(en)
|
2013-12-05 |
2023-08-15 |
The Broad Institute Inc. |
Polymorphic gene typing and somatic change detection using sequencing data
|
CN106456724A
(en)
|
2013-12-20 |
2017-02-22 |
博德研究所 |
Combination therapy with neoantigen vaccine
|
MX2017000646A
(en)
|
2014-07-15 |
2017-04-27 |
Juno Therapeutics Inc |
Engineered cells for adoptive cell therapy.
|
ES2841274T3
(en)
*
|
2014-08-04 |
2021-07-07 |
Hutchinson Fred Cancer Res |
T-cell immunotherapy specific for WT-1
|
TWI805109B
(en)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
Antibodies and chimeric antigen receptors specific for cd19
|
SG11201703203RA
(en)
|
2014-10-20 |
2017-05-30 |
Juno Therapeutics Inc |
Methods and compositions for dosing in adoptive cell therapy
|
LT3215601T
(en)
|
2014-11-05 |
2020-08-25 |
Juno Therapeutics, Inc. |
Methods for transduction and cell processing
|
JP7068820B2
(en)
|
2014-12-03 |
2022-05-17 |
ジュノー セラピューティクス インコーポレイテッド |
Methods and Compositions for Adoptive Cell Therapy
|
WO2016100977A1
(en)
|
2014-12-19 |
2016-06-23 |
The Broad Institute Inc. |
Methods for profiling the t-cel- receptor repertoire
|
EP3234193B1
(en)
|
2014-12-19 |
2020-07-15 |
Massachusetts Institute of Technology |
Molecular biomarkers for cancer immunotherapy
|
MA41346A
(en)
|
2015-01-12 |
2017-11-21 |
Juno Therapeutics Inc |
POST-TRANSCRIPTIONAL REGULATORY ELEMENTS OF MODIFIED HEPATITIS
|
CA2973964A1
(en)
|
2015-01-16 |
2016-07-21 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for ror1
|
WO2016166568A1
(en)
|
2015-04-16 |
2016-10-20 |
Juno Therapeutics Gmbh |
Methods, kits and apparatus for expanding a population of cells
|
CR20230191A
(en)
|
2015-05-20 |
2023-07-06 |
Dana Farber Cancer Inst Inc |
SHARED NEOANTIGENS (Div. exp 2017-584)
|
CN108174607A
(en)
|
2015-05-29 |
2018-06-15 |
朱诺治疗学股份有限公司 |
For adjusting the composition and method of inhibition interaction in genetically engineered cell
|
CA3012607A1
(en)
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Crispr enzymes and systems
|
MA42895A
(en)
|
2015-07-15 |
2018-05-23 |
Juno Therapeutics Inc |
MODIFIED CELLS FOR ADOPTIVE CELL THERAPY
|
US11142565B2
(en)
|
2015-09-24 |
2021-10-12 |
Abvitro Llc |
Broadly neutralizing anti-HIV-1 antibodies that bind to an N-glycan epitope on the envelope
|
US10928392B2
(en)
|
2015-09-25 |
2021-02-23 |
Abvitro Llc |
High throughput process for T cell receptor target identification of natively-paired T cell receptor sequences
|
WO2017069958A2
(en)
|
2015-10-09 |
2017-04-27 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
MA45488A
(en)
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics Gmbh |
CELL CULTURE PROCESSES, KITS AND APPARATUS
|
MA45489A
(en)
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics Gmbh |
CELL CULTURE PROCESSES, ASSOCIATED KITS AND APPARATUS
|
AU2016341527B2
(en)
|
2015-10-22 |
2023-04-27 |
Juno Therapeutics Gmbh |
Methods, kits, agents and apparatuses for transduction
|
WO2017075451A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
|
WO2017075478A2
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by use of immune cell gene signatures
|
WO2017075465A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
|
US11020429B2
(en)
|
2015-11-05 |
2021-06-01 |
Juno Therapeutics, Inc. |
Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy
|
MA44314A
(en)
|
2015-11-05 |
2018-09-12 |
Juno Therapeutics Inc |
CHEMERICAL RECEPTORS CONTAINING TRAF-INDUCING DOMAINS, AND ASSOCIATED COMPOSITIONS AND METHODS
|
US11001622B2
(en)
|
2015-11-19 |
2021-05-11 |
The Brigham And Women's Hospital, Inc. |
Method of treating autoimmune disease with lymphocyte antigen CD5-like (CD5L) protein
|
EP4212166A1
(en)
|
2015-12-03 |
2023-07-19 |
Juno Therapeutics, Inc. |
Compositions and methods for reducing immune responses against cell therapies
|
US20180355014A1
(en)
|
2015-12-03 |
2018-12-13 |
Juno Therapeutics, Inc. |
Modified chimeric receptors and related compositions and methods
|
MA43377A
(en)
|
2015-12-04 |
2021-05-19 |
Hutchinson Fred Cancer Res |
METHODS AND COMPOSITIONS RELATED TO TOXICITY ASSOCIATED WITH CELL THERAPY
|
WO2017112944A1
(en)
*
|
2015-12-23 |
2017-06-29 |
Fred Hutchinson Cancer Research Center |
High affinity t cell receptors and uses thereof
|
US20190355459A1
(en)
|
2016-03-16 |
2019-11-21 |
Juno Therapeutics, Inc. |
Methods for adaptive design of a treatment regimen and related treatments
|
EP3430548A1
(en)
|
2016-03-16 |
2019-01-23 |
Juno Therapeutics, Inc. |
Methods for determining dosing of a therapeutic agent and related treatments
|
MX2018011480A
(en)
|
2016-03-22 |
2019-03-28 |
Seattle Children´S Hospital Dba Seattle Children´S Res Institute |
Early intervention methods to prevent or ameliorate toxicity.
|
US20190346442A1
(en)
|
2016-04-18 |
2019-11-14 |
The Broad Institute, Inc. |
Improved hla epitope prediction
|
WO2017193104A1
(en)
|
2016-05-06 |
2017-11-09 |
Fred Hutchinson Cancer Research Center |
T-cell immunotherapy specific for mart-1
|
US20190136230A1
(en)
|
2016-05-06 |
2019-05-09 |
Juno Therapeutics, Inc. |
Genetically engineered cells and methods of making the same
|
MX2018014599A
(en)
|
2016-05-27 |
2019-02-28 |
Aadigen Llc |
Peptides and nanoparticles for intracellular delivery of genome-editing molecules.
|
MX2018014991A
(en)
|
2016-06-03 |
2019-08-29 |
Memorial Sloan Kettering Cancer Center |
Adoptive cell therapies as early treatment options.
|
MA45341A
(en)
|
2016-06-06 |
2019-04-10 |
Hutchinson Fred Cancer Res |
METHODS FOR TREATING B-LYMPHOCYTE MALIGNITIES USING ADOPTIVE CELL THERAPY
|
MA45491A
(en)
|
2016-06-27 |
2019-05-01 |
Juno Therapeutics Inc |
CMH-E RESTRICTED EPITOPES, BINDING MOLECULES AND RELATED METHODS AND USES
|
WO2018005559A1
(en)
|
2016-06-27 |
2018-01-04 |
Juno Therapeutics, Inc. |
Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
|
MX2019001184A
(en)
|
2016-07-29 |
2019-09-26 |
Juno Therapeutics Inc |
Anti-idiotypic antibodies against anti-cd19 antibodies.
|
AU2017301880C1
(en)
|
2016-07-29 |
2022-04-21 |
Juno Therapeutics, Inc. |
Immunomodulatory polypeptides and related compositions and methods
|
CA3031994A1
(en)
|
2016-07-29 |
2018-02-01 |
Juno Therapeutics, Inc. |
Methods for assessing the presence or absence of replication competent virus
|
WO2018035364A1
(en)
|
2016-08-17 |
2018-02-22 |
The Broad Institute Inc. |
Product and methods useful for modulating and evaluating immune responses
|
US20190262399A1
(en)
|
2016-09-07 |
2019-08-29 |
The Broad Institute, Inc. |
Compositions and methods for evaluating and modulating immune responses
|
CA3035829A1
(en)
|
2016-09-12 |
2018-03-15 |
Juno Therapeutics, Inc. |
Perfusion bioreactor bag assemblies
|
EP4353319A2
(en)
|
2016-09-28 |
2024-04-17 |
Atossa Therapeutics, Inc. |
Methods of adoptive cell therapy
|
MX2019003768A
(en)
|
2016-10-03 |
2019-06-24 |
Juno Therapeutics Inc |
Hpv-specific binding molecules.
|
WO2018067991A1
(en)
|
2016-10-07 |
2018-04-12 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
EP4190335A1
(en)
|
2016-10-13 |
2023-06-07 |
Juno Therapeutics, Inc. |
Immunotherapy methods and compositions involving tryptophan metabolic pathway modulators
|
MA46783A
(en)
|
2016-11-03 |
2019-09-11 |
Juno Therapeutics Inc |
T-CELL THERAPY AND BTK INHIBITOR POLYTHERAPY
|
US20190292246A1
(en)
|
2016-11-03 |
2019-09-26 |
Juno Therapeutics, Inc. |
Combination therapy of a cell based therapy and a microglia imhibitor
|
AU2017356322B2
(en)
*
|
2016-11-14 |
2023-09-21 |
Fred Hutchinson Cancer Center |
High affinity merkel cell polyomavirus T antigen-specific TCRs and uses thereof
|
EP4242298A2
(en)
|
2016-12-02 |
2023-09-13 |
Taiga Biotechnologies, Inc. |
Nanoparticle formulations
|
CN110290807A
(en)
|
2016-12-03 |
2019-09-27 |
朱诺治疗学股份有限公司 |
The method for determining CAR-T cell administration
|
WO2018102786A1
(en)
|
2016-12-03 |
2018-06-07 |
Juno Therapeutics, Inc. |
Methods for modulation of car-t cells
|
CN110545826A
(en)
|
2016-12-03 |
2019-12-06 |
朱诺治疗学股份有限公司 |
Methods and compositions for using therapeutic T cells in combination with kinase inhibitors
|
EP3548611A1
(en)
|
2016-12-05 |
2019-10-09 |
Juno Therapeutics, Inc. |
Production of engineered cells for adoptive cell therapy
|
US11821027B2
(en)
|
2017-01-10 |
2023-11-21 |
Juno Therapeutics, Inc. |
Epigenetic analysis of cell therapy and related methods
|
US11517627B2
(en)
|
2017-01-20 |
2022-12-06 |
Juno Therapeutics Gmbh |
Cell surface conjugates and related cell compositions and methods
|
EP3574116A1
(en)
|
2017-01-24 |
2019-12-04 |
The Broad Institute, Inc. |
Compositions and methods for detecting a mutant variant of a polynucleotide
|
US20200096521A1
(en)
|
2017-02-12 |
2020-03-26 |
Neon Therapeutics, Inc. |
Hla-based methods and compositions and uses thereof
|
BR112019017120A8
(en)
|
2017-02-17 |
2023-05-02 |
Hutchinson Fred Cancer Res |
COMBINATION THERAPIES FOR TREATMENT OF CANCER AND BCMA-RELATED AUTOIMMUNE DISORDERS
|
JP7228522B2
(en)
|
2017-02-27 |
2023-02-24 |
ジュノー セラピューティクス インコーポレイテッド |
Compositions, articles of manufacture, and methods for dosing in cell therapy
|
US11850262B2
(en)
|
2017-02-28 |
2023-12-26 |
Purdue Research Foundation |
Compositions and methods for CAR T cell therapy
|
MX2019010906A
(en)
|
2017-03-14 |
2020-02-12 |
Juno Therapeutics Inc |
Methods for cryogenic storage.
|
EP3606518A4
(en)
|
2017-04-01 |
2021-04-07 |
The Broad Institute, Inc. |
Methods and compositions for detecting and modulating an immunotherapy resistance gene signature in cancer
|
JP7284707B2
(en)
|
2017-04-07 |
2023-05-31 |
ジュノー セラピューティクス インコーポレイテッド |
Engineered Cells Expressing Prostate-Specific Membrane Antigen (PSMA) or Modified Forms Thereof and Related Methods
|
WO2018191553A1
(en)
|
2017-04-12 |
2018-10-18 |
Massachusetts Eye And Ear Infirmary |
Tumor signature for metastasis, compositions of matter methods of use thereof
|
EP3610261A1
(en)
|
2017-04-14 |
2020-02-19 |
Juno Therapeutics, Inc. |
Methods for assessing cell surface glycosylation
|
MX2019012398A
(en)
|
2017-04-18 |
2020-09-25 |
Broad Inst Inc |
Compositions for detecting secretion and methods of use.
|
DK3612557T3
(en)
|
2017-04-18 |
2022-04-19 |
Fujifilm Cellular Dynamics Inc |
ANTIGEN-SPECIFIC IMMUNE EFFECTOR CELLS
|
EP3615653A1
(en)
|
2017-04-27 |
2020-03-04 |
Juno Therapeutics GmbH |
Oligomeric particle reagents and methods of use thereof
|
IL310031A
(en)
|
2017-05-01 |
2024-03-01 |
Juno Therapeutics Inc |
Combination of a cell therapy and an immunomodulatory compound
|
WO2018218038A1
(en)
|
2017-05-24 |
2018-11-29 |
Effector Therapeutics, Inc. |
Methods and compositions for cellular immunotherapy
|
MX2019014268A
(en)
|
2017-06-02 |
2020-08-03 |
Juno Therapeutics Inc |
Articles of manufacture and methods for treatment using adoptive cell therapy.
|
US11740231B2
(en)
|
2017-06-02 |
2023-08-29 |
Juno Therapeutics, Inc. |
Articles of manufacture and methods related to toxicity associated with cell therapy
|
WO2018232195A1
(en)
|
2017-06-14 |
2018-12-20 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
PT3538645T
(en)
|
2017-06-20 |
2021-04-15 |
Inst Curie |
Immune cells defective for suv39h1
|
US20210147800A1
(en)
|
2017-06-22 |
2021-05-20 |
Board Of Regents, The University Of Texas System |
Methods for producing regulatory immune cells and uses thereof
|
CA3067602A1
(en)
|
2017-06-29 |
2019-01-03 |
Juno Therapeutics, Inc. |
Mouse model for assessing toxicities associated with immunotherapies
|
CN111246861A
(en)
|
2017-07-29 |
2020-06-05 |
朱诺治疗学股份有限公司 |
Reagent for amplifying cell expressing recombinant receptor
|
JP6731114B2
(en)
|
2017-08-03 |
2020-07-29 |
タイガ バイオテクノロジーズ,インク. |
Methods and compositions for the treatment of melanoma
|
US10149898B2
(en)
|
2017-08-03 |
2018-12-11 |
Taiga Biotechnologies, Inc. |
Methods and compositions for the treatment of melanoma
|
MX2020001491A
(en)
|
2017-08-09 |
2020-08-06 |
Juno Therapeutics Inc |
Methods and compositions for preparing genetically engineered cells.
|
MA49979A
(en)
|
2017-08-09 |
2020-06-17 |
Juno Therapeutics Inc |
PROCESSES FOR THE PRODUCTION OF GENETICALLY MODIFIED CELL COMPOSITIONS AND RELATED COMPOSITIONS
|
MA50057A
(en)
|
2017-09-01 |
2020-07-08 |
Juno Therapeutics Inc |
GENE EXPRESSION AND ASSESSMENT OF A RISK OF DEVELOPING TOXICITY FOLLOWING CELL THERAPY
|
EP3679370A1
(en)
|
2017-09-07 |
2020-07-15 |
Juno Therapeutics, Inc. |
Methods of identifying cellular attributes related to outcomes associated with cell therapy
|
CN109517820B
(en)
|
2017-09-20 |
2021-09-24 |
北京宇繁生物科技有限公司 |
gRNA of target HPK1 and HPK1 gene editing method
|
EP3684397A4
(en)
|
2017-09-21 |
2021-08-18 |
The Broad Institute, Inc. |
Systems, methods, and compositions for targeted nucleic acid editing
|
CA3080546A1
(en)
|
2017-10-03 |
2019-04-11 |
Juno Therapeutics, Inc. |
Hpv-specific binding molecules
|
WO2019084055A1
(en)
|
2017-10-23 |
2019-05-02 |
Massachusetts Institute Of Technology |
Calling genetic variation from single-cell transcriptomes
|
CA3084514A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Process for generating therapeutic compositions of engineered cells
|
US11851679B2
(en)
|
2017-11-01 |
2023-12-26 |
Juno Therapeutics, Inc. |
Method of assessing activity of recombinant antigen receptors
|
CA3081456A1
(en)
|
2017-11-01 |
2019-05-09 |
Editas Medicine, Inc. |
Methods, compositions and components for crispr-cas9 editing of tgfbr2 in t cells for immunotherapy
|
EP3703750A1
(en)
|
2017-11-01 |
2020-09-09 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for b-cell maturation antigen and encoding polynucleotides
|
WO2019089848A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods associated with tumor burden for assessing response to a cell therapy
|
EP3704229B1
(en)
|
2017-11-01 |
2023-12-20 |
Juno Therapeutics, Inc. |
Process for producing a t cell composition
|
WO2019089858A2
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
SG11202003501XA
(en)
|
2017-11-01 |
2020-05-28 |
Juno Therapeutics Inc |
Antibodies and chimeric antigen receptors specific for b-cell maturation antigen
|
US20230137729A1
(en)
|
2017-11-06 |
2023-05-04 |
Editas Medicine, Inc. |
Methods, compositions and components for crispr-cas9 editing of cblb in t cells for immunotherapy
|
CA3080395A1
(en)
|
2017-11-06 |
2019-05-09 |
Juno Therapeutics, Inc. |
Combination of a cell therapy and a gamma secretase inhibitor
|
US20200330983A1
(en)
|
2017-11-10 |
2020-10-22 |
Juno Therapeutics, Inc. |
Closed-system cryogenic vessels
|
EP3710039A4
(en)
|
2017-11-13 |
2021-08-04 |
The Broad Institute, Inc. |
Methods and compositions for treating cancer by targeting the clec2d-klrb1 pathway
|
MA51210A
(en)
|
2017-12-01 |
2020-10-07 |
Juno Therapeutics Inc |
METHODS FOR DOSING AND MODULATING GENETICALLY MODIFIED CELLS
|
JP2021505615A
(en)
|
2017-12-08 |
2021-02-18 |
ジュノー セラピューティクス インコーポレイテッド |
Phenotypic markers for cell therapy and related methods
|
MA51114A
(en)
|
2017-12-08 |
2020-10-14 |
Juno Therapeutics Inc |
PROCESS FOR PRODUCING A COMPOSITIONS OF MODIFIED T-LYMPHOCYTES
|
EA202091407A1
(en)
|
2017-12-08 |
2020-10-20 |
Джуно Терапьютикс, Инк. |
COMPOSITION OF A SERUM-FREE MEDIUM FOR CELL CULTIVATION AND METHODS OF ITS APPLICATION
|
MX2020006226A
(en)
*
|
2017-12-13 |
2020-11-18 |
Inovio Pharmaceuticals Inc |
Cancer vaccines targeting mesothelin and uses thereof.
|
KR20200110745A
(en)
|
2017-12-15 |
2020-09-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Anti-CCT5 binding molecule and method of use thereof
|
US11793867B2
(en)
|
2017-12-18 |
2023-10-24 |
Biontech Us Inc. |
Neoantigens and uses thereof
|
WO2019139972A1
(en)
|
2018-01-09 |
2019-07-18 |
Board Of Regents, The University Of Texas System |
T cell receptors for immunotherapy
|
AU2019209428A1
(en)
|
2018-01-22 |
2020-07-30 |
Endocyte, Inc. |
Methods of use for CAR T cells
|
WO2019152747A1
(en)
|
2018-01-31 |
2019-08-08 |
Juno Therapeutics, Inc. |
Methods and reagents for assessing the presence or absence of replication competent virus
|
KR20200128014A
(en)
|
2018-01-31 |
2020-11-11 |
셀진 코포레이션 |
Adoptive cell therapy and combination therapy with checkpoint inhibitors
|
US20210046159A1
(en)
|
2018-03-09 |
2021-02-18 |
Ospedale San Raffaele S.R.L. |
Il-1 antagonist and toxicity induced by cell therapy
|
BR112020020245A2
(en)
|
2018-04-05 |
2021-04-06 |
Editas Medicine, Inc. |
METHODS OF PRODUCING CELLS EXPRESSING A RECOMBINANT RECEIVER AND RELATED COMPOSITIONS
|
CA3095027A1
(en)
|
2018-04-05 |
2019-10-10 |
Juno Therapeutics, Inc. |
T cell receptors and engineered cells expressing same
|
SG11202010642TA
(en)
|
2018-05-03 |
2020-11-27 |
Juno Therapeutics Inc |
Combination therapy of a chimeric antigen receptor (car) t cell therapy and a kinase inhibitor
|
US20210371932A1
(en)
|
2018-06-01 |
2021-12-02 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
EP3806888B1
(en)
|
2018-06-12 |
2024-01-31 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
CA3108698A1
(en)
|
2018-08-09 |
2020-02-13 |
Juno Therapeutics, Inc. |
Methods for assessing integrated nucleic acids
|
JP2021533746A
(en)
|
2018-08-09 |
2021-12-09 |
ジュノー セラピューティクス インコーポレイテッド |
Methods for producing engineered cells and their compositions
|
WO2020041387A1
(en)
|
2018-08-20 |
2020-02-27 |
The Brigham And Women's Hospital, Inc. |
Degradation domain modifications for spatio-temporal control of rna-guided nucleases
|
WO2020068304A2
(en)
|
2018-08-20 |
2020-04-02 |
The Broad Institute, Inc. |
Inhibitors of rna-guided nuclease target binding and uses thereof
|
WO2020041384A1
(en)
|
2018-08-20 |
2020-02-27 |
The Broad Institute, Inc. |
3-phenyl-2-cyano-azetidine derivatives, inhibitors of rna-guided nuclease activity
|
KR20210081341A
(en)
|
2018-09-11 |
2021-07-01 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Methods for Mass Spectrometry Analysis of Engineered Cell Compositions
|
WO2020072700A1
(en)
|
2018-10-02 |
2020-04-09 |
Dana-Farber Cancer Institute, Inc. |
Hla single allele lines
|
WO2020081730A2
(en)
|
2018-10-16 |
2020-04-23 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating microenvironment
|
WO2020092455A2
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Car t cell transcriptional atlas
|
AU2019370705A1
(en)
|
2018-10-31 |
2021-05-27 |
Juno Therapeutics Gmbh |
Methods for selection and stimulation of cells and apparatus for same
|
CN113646335A
(en)
|
2018-11-01 |
2021-11-12 |
朱诺治疗学股份有限公司 |
Methods of treatment using chimeric antigen receptors specific for B cell maturation antigen
|
MX2021005021A
(en)
|
2018-11-06 |
2021-08-11 |
Juno Therapeutics Inc |
Process for producing genetically engineered t cells.
|
AU2019377854A1
(en)
|
2018-11-08 |
2021-05-27 |
Juno Therapeutics, Inc. |
Methods and combinations for treatment and T cell modulation
|
AU2019381827A1
(en)
|
2018-11-16 |
2021-06-10 |
Juno Therapeutics, Inc. |
Methods of dosing engineered T cells for the treatment of B cell malignancies
|
US20220033848A1
(en)
|
2018-11-19 |
2022-02-03 |
Board Of Regents, The University Of Texas System |
A modular, polycistronic vector for car and tcr transduction
|
AU2019386140A1
(en)
|
2018-11-28 |
2021-06-24 |
Board Of Regents, The University Of Texas System |
Multiplex genome editing of immune cells to enhance functionality and resistance to suppressive environment
|
US20220033778A1
(en)
|
2018-11-29 |
2022-02-03 |
Board Of Regents, The University Of Texas System |
Methods for ex vivo expansion of natural killer cells and use thereof
|
SG11202105502RA
(en)
|
2018-11-30 |
2021-06-29 |
Juno Therapeutics Inc |
Methods for treatment using adoptive cell therapy
|
JP2022513689A
(en)
|
2018-11-30 |
2022-02-09 |
ジュノー セラピューティクス インコーポレイテッド |
Methods for Administration and Treatment of B-Cell Malignancies in Adoptive Cell Therapy
|
US20220062394A1
(en)
|
2018-12-17 |
2022-03-03 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
WO2020132586A1
(en)
|
2018-12-21 |
2020-06-25 |
Neon Therapeutics, Inc. |
Method and systems for prediction of hla class ii-specific epitopes and characterization of cd4+ t cells
|
US11739156B2
(en)
|
2019-01-06 |
2023-08-29 |
The Broad Institute, Inc. Massachusetts Institute of Technology |
Methods and compositions for overcoming immunosuppression
|
KR20210122272A
(en)
|
2019-01-29 |
2021-10-08 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Antibodies and chimeric antigen receptors specific for receptor tyrosine kinase-like orphan receptor 1 (ROR1)
|
US20220154282A1
(en)
|
2019-03-12 |
2022-05-19 |
The Broad Institute, Inc. |
Detection means, compositions and methods for modulating synovial sarcoma cells
|
US20220142948A1
(en)
|
2019-03-18 |
2022-05-12 |
The Broad Institute, Inc. |
Compositions and methods for modulating metabolic regulators of t cell pathogenicity
|
AU2020265749A1
(en)
|
2019-05-01 |
2022-01-06 |
Juno Therapeutics, Inc. |
Cells expressing a chimeric receptor from a modified CD247 locus, related polynucleotides and methods
|
MA55811A
(en)
|
2019-05-01 |
2022-03-09 |
Editas Medicine Inc |
CELLS EXPRESSING A RECOMBINANT RECEPTOR BASED ON A MODIFIED TGFBR2 LOCUS, AND RELATED POLYNUCLEOTIDES AND METHODS
|
WO2020236967A1
(en)
|
2019-05-20 |
2020-11-26 |
The Broad Institute, Inc. |
Random crispr-cas deletion mutant
|
US20220226464A1
(en)
|
2019-05-28 |
2022-07-21 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating immune responses
|
MX2021015125A
(en)
|
2019-06-07 |
2022-04-06 |
Juno Therapeutics Inc |
Automated t cell culture.
|
CN114269371A
(en)
|
2019-06-12 |
2022-04-01 |
朱诺治疗学股份有限公司 |
Combination therapy of cell-mediated cytotoxic therapy with an inhibitor of pro-survival BCL2family protein
|
CN114222815A
(en)
|
2019-07-23 |
2022-03-22 |
记忆疗法公司 |
SUV39H1 deficient immune cells
|
US20220282333A1
(en)
|
2019-08-13 |
2022-09-08 |
The General Hospital Corporation |
Methods for predicting outcomes of checkpoint inhibition and treatment thereof
|
WO2021035194A1
(en)
|
2019-08-22 |
2021-02-25 |
Juno Therapeutics, Inc. |
Combination therapy of a t cell therapy and an enhancer of zeste homolog 2 (ezh2) inhibitor and related methods
|
EP4022637A2
(en)
|
2019-08-30 |
2022-07-06 |
Juno Therapeutics, Inc. |
Machine learning methods for classifying cells
|
WO2021041922A1
(en)
|
2019-08-30 |
2021-03-04 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
MX2022002578A
(en)
|
2019-09-02 |
2022-06-02 |
Inst Curie |
Immunotherapy targeting tumor neoantigenic peptides.
|
CN114729368A
(en)
|
2019-09-09 |
2022-07-08 |
斯克里贝治疗公司 |
Compositions and methods for immunotherapy
|
US11793787B2
(en)
|
2019-10-07 |
2023-10-24 |
The Broad Institute, Inc. |
Methods and compositions for enhancing anti-tumor immunity by targeting steroidogenesis
|
EP4048304A1
(en)
|
2019-10-22 |
2022-08-31 |
Institut Curie |
Immunotherapy targeting tumor neoantigenic peptides
|
US11844800B2
(en)
|
2019-10-30 |
2023-12-19 |
Massachusetts Institute Of Technology |
Methods and compositions for predicting and preventing relapse of acute lymphoblastic leukemia
|
WO2021084050A1
(en)
|
2019-10-30 |
2021-05-06 |
Juno Therapeutics Gmbh |
Cell selection and/or stimulation devices and methods of use
|
AU2020379043A1
(en)
|
2019-11-07 |
2022-06-02 |
Juno Therapeutics, Inc. |
Combination of a T cell therapy and (S)-3-[4-(4-morpholin-4-ylmethyl-benzyloxy)-1-oxo-1,3-dihydro-isoindol-2-yl]-piperidine-2,6-dione
|
JP2023504737A
(en)
|
2019-12-06 |
2023-02-06 |
ジュノー セラピューティクス インコーポレイテッド |
Methods relating to toxicity and efficacy associated with cell therapy for treating B-cell malignancies
|
BR112022010627A2
(en)
|
2019-12-06 |
2022-08-16 |
Juno Therapeutics Inc |
ANTI-IDIOTYPIC ANTIBODIES TO BINDING DOMAINS TARGETED BY BCMA AND RELATED COMPOSITIONS AND METHODS
|
CN115335399A
(en)
|
2019-12-06 |
2022-11-11 |
朱诺治疗学股份有限公司 |
Anti-idiotype antibodies directed against GPRC5D target binding domains and related compositions and methods
|
US11865168B2
(en)
|
2019-12-30 |
2024-01-09 |
Massachusetts Institute Of Technology |
Compositions and methods for treating bacterial infections
|
KR20220145341A
(en)
|
2020-01-24 |
2022-10-28 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Methods of Administration and Treatment of Follicular Lymphoma and Marginal Zone Lymphoma in Adoptive Cell Therapy
|
KR20220146480A
(en)
|
2020-01-28 |
2022-11-01 |
주노 쎄러퓨티크스 인코퍼레이티드 |
T cell transduction method
|
US20230190798A1
(en)
|
2020-02-12 |
2023-06-22 |
Juno Therapeutics, Inc. |
Cd19-directed chimeric antigen receptor t cell compositions and methods and uses thereof
|
MX2022009830A
(en)
|
2020-02-12 |
2022-10-28 |
Juno Therapeutics Inc |
Bcma-directed chimeric antigen receptor t cell compositions and methods and uses thereof.
|
CA3168337A1
(en)
|
2020-02-17 |
2021-08-26 |
Marie-Andree Forget |
Methods for expansion of tumor infiltrating lymphocytes and use thereof
|
WO2021207689A2
(en)
|
2020-04-10 |
2021-10-14 |
Juno Therapeutics, Inc. |
Methods and uses related to cell therapy engineered with a chimeric antigen receptor targeting b-cell maturation antigen
|
US20210340524A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
EP4149952A1
(en)
|
2020-05-12 |
2023-03-22 |
Institut Curie |
Neoantigenic epitopes associated with sf3b1 mutations
|
KR20230024283A
(en)
|
2020-05-13 |
2023-02-20 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Methods for identifying features associated with clinical response and uses thereof
|
KR20230022868A
(en)
|
2020-05-13 |
2023-02-16 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Method for producing donor-batch cells expressing a recombinant acceptor
|
US20230212256A1
(en)
|
2020-05-21 |
2023-07-06 |
Board Of Regents, The University Of Texas System |
T cell receptors with vgll1 specificity and uses thereof
|
WO2021260186A1
(en)
|
2020-06-26 |
2021-12-30 |
Juno Therapeutics Gmbh |
Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
|
JP2023535501A
(en)
|
2020-07-30 |
2023-08-17 |
アンスティテュ・クリー |
Immune cells defective in SOCS1
|
KR20230095918A
(en)
|
2020-08-05 |
2023-06-29 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Anti-idiotype antibodies to the ROR1-target binding domain and related compositions and methods
|
CN114106144B
(en)
*
|
2020-08-27 |
2024-01-26 |
溧阳瑅赛生物医药有限公司 |
TCR for identifying HLA-A 02/WT1 target and application thereof
|
CA3201499A1
(en)
|
2020-11-13 |
2022-05-19 |
Catamaran Bio, Inc. |
Genetically modified natural killer cells and methods of use thereof
|
WO2022133030A1
(en)
|
2020-12-16 |
2022-06-23 |
Juno Therapeutics, Inc. |
Combination therapy of a cell therapy and a bcl2 inhibitor
|
EP4274901A1
(en)
|
2021-01-11 |
2023-11-15 |
Sana Biotechnology, Inc. |
Use of cd8-targeted viral vectors
|
WO2022187280A1
(en)
|
2021-03-01 |
2022-09-09 |
Dana-Farber Cancer Institute, Inc. |
Personalized redirection and reprogramming of t cells for precise targeting of tumors
|
KR20230165771A
(en)
|
2021-03-03 |
2023-12-05 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Combination of T cell therapy and DGK inhibitor
|
KR20230172630A
(en)
|
2021-03-11 |
2023-12-22 |
므네모 테라퓨틱스 |
Tumor Neoantigenic Peptide
|
AU2022235060A1
(en)
|
2021-03-11 |
2023-09-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Tumor neoantigenic peptides and uses thereof
|
JP2024510217A
(en)
|
2021-03-11 |
2024-03-06 |
アンスティテュ・クリー |
Transmembrane neoantigen peptide
|
CA3210581A1
(en)
|
2021-03-22 |
2022-09-29 |
Neil HAIG |
Methods of determining potency of a therapeutic cell composition
|
EP4314280A1
(en)
|
2021-03-22 |
2024-02-07 |
Juno Therapeutics, Inc. |
Method to assess potency of viral vector particles
|
KR20240005700A
(en)
|
2021-03-29 |
2024-01-12 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Dosing and Treatment Methods Using Combination of Checkpoint Inhibitor Therapy and CAR T Cell Therapy
|
IL307257A
(en)
|
2021-03-29 |
2023-11-01 |
Juno Therapeutics Inc |
Combination of a car t cell therapy and an immunomodulatory compound for treatment of lymphoma
|
EP4334341A2
(en)
|
2021-05-06 |
2024-03-13 |
Juno Therapeutics GmbH |
Methods for stimulating and transducing t cells
|
WO2023015217A1
(en)
|
2021-08-04 |
2023-02-09 |
Sana Biotechnology, Inc. |
Use of cd4-targeted viral vectors
|
CA3228262A1
(en)
|
2021-08-04 |
2023-02-09 |
The Regents Of The University Of Colorado, A Body Corporate |
Lat activating chimeric antigen receptor t cells and methods of use thereof
|
WO2023105000A1
(en)
|
2021-12-09 |
2023-06-15 |
Zygosity Limited |
Vector
|
TW202342757A
(en)
|
2021-12-17 |
2023-11-01 |
美商薩那生物科技公司 |
Modified paramyxoviridae attachment glycoproteins
|
WO2023115039A2
(en)
|
2021-12-17 |
2023-06-22 |
Sana Biotechnology, Inc. |
Modified paramyxoviridae fusion glycoproteins
|
WO2023126458A1
(en)
|
2021-12-28 |
2023-07-06 |
Mnemo Therapeutics |
Immune cells with inactivated suv39h1 and modified tcr
|
WO2023139269A1
(en)
|
2022-01-21 |
2023-07-27 |
Mnemo Therapeutics |
Modulation of suv39h1 expression by rnas
|
WO2023147515A1
(en)
|
2022-01-28 |
2023-08-03 |
Juno Therapeutics, Inc. |
Methods of manufacturing cellular compositions
|
WO2023150518A1
(en)
|
2022-02-01 |
2023-08-10 |
Sana Biotechnology, Inc. |
Cd3-targeted lentiviral vectors and uses thereof
|
WO2023178348A1
(en)
|
2022-03-18 |
2023-09-21 |
The Regents Of The University Of Colorado, A Body Corporate |
Genetically engineered t-cell co-receptors and methods of use thereof
|
WO2023180552A1
(en)
|
2022-03-24 |
2023-09-28 |
Institut Curie |
Immunotherapy targeting tumor transposable element derived neoantigenic peptides in glioblastoma
|
WO2023193015A1
(en)
|
2022-04-01 |
2023-10-05 |
Sana Biotechnology, Inc. |
Cytokine receptor agonist and viral vector combination therapies
|
WO2023196921A1
(en)
|
2022-04-06 |
2023-10-12 |
The Regents Of The University Of Colorado, A Body Corporate |
Granzyme expressing t cells and methods of use
|
WO2023196933A1
(en)
|
2022-04-06 |
2023-10-12 |
The Regents Of The University Of Colorado, A Body Corporate |
Chimeric antigen receptor t cells and methods of use thereof
|
WO2023211972A1
(en)
|
2022-04-28 |
2023-11-02 |
Medical University Of South Carolina |
Chimeric antigen receptor modified regulatory t cells for treating cancer
|
WO2023213969A1
(en)
|
2022-05-05 |
2023-11-09 |
Juno Therapeutics Gmbh |
Viral-binding protein and related reagents, articles, and methods of use
|
WO2023220655A1
(en)
|
2022-05-11 |
2023-11-16 |
Celgene Corporation |
Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
|
EP4279085A1
(en)
|
2022-05-20 |
2023-11-22 |
Mnemo Therapeutics |
Compositions and methods for treating a refractory or relapsed cancer or a chronic infectious disease
|
WO2023230581A1
(en)
|
2022-05-25 |
2023-11-30 |
Celgene Corporation |
Methods of manufacturing t cell therapies
|
WO2023250400A1
(en)
|
2022-06-22 |
2023-12-28 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
WO2024006960A1
(en)
|
2022-06-29 |
2024-01-04 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids
|
WO2024044779A2
(en)
|
2022-08-26 |
2024-02-29 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for delta-like ligand 3 (dll3)
|
WO2024054944A1
(en)
|
2022-09-08 |
2024-03-14 |
Juno Therapeutics, Inc. |
Combination of a t cell therapy and continuous or intermittent dgk inhibitor dosing
|
WO2024062138A1
(en)
|
2022-09-23 |
2024-03-28 |
Mnemo Therapeutics |
Immune cells comprising a modified suv39h1 gene
|