NO2017025I1 - Rekombinant FSH (rFSH) innbefattende alfa2,3-sialylering og alfa2,6-sialylering hvor 80% eller mer av den totale sialylering er alfa2,3-sialylering og hvor fra 5% til 20% av den totale sialylering er alfa2,6- sialylering, spesielt follitropin delta. - Google Patents

Rekombinant FSH (rFSH) innbefattende alfa2,3-sialylering og alfa2,6-sialylering hvor 80% eller mer av den totale sialylering er alfa2,3-sialylering og hvor fra 5% til 20% av den totale sialylering er alfa2,6- sialylering, spesielt follitropin delta.

Info

Publication number
NO2017025I1
NO2017025I1 NO2017025C NO2017025C NO2017025I1 NO 2017025 I1 NO2017025 I1 NO 2017025I1 NO 2017025 C NO2017025 C NO 2017025C NO 2017025 C NO2017025 C NO 2017025C NO 2017025 I1 NO2017025 I1 NO 2017025I1
Authority
NO
Norway
Prior art keywords
sialylation
alpha2
total
rfsh
follitropin
Prior art date
Application number
NO2017025C
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English (en)
Norwegian (no)
Original Assignee
Ferring Bv
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39717519&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO2017025(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferring Bv filed Critical Ferring Bv
Publication of NO2017025I1 publication Critical patent/NO2017025I1/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C12Y204/99006—N-Acetyllactosaminide alpha-2,3-sialyltransferase (2.4.99.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO2017025C 2008-04-16 2017-06-06 Rekombinant FSH (rFSH) innbefattende alfa2,3-sialylering og alfa2,6-sialylering hvor 80% eller mer av den totale sialylering er alfa2,3-sialylering og hvor fra 5% til 20% av den totale sialylering er alfa2,6- sialylering, spesielt follitropin delta. NO2017025I1 (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4542408P 2008-04-16 2008-04-16
EP08251528 2008-04-25
EP09733497.3A EP2268666B1 (en) 2008-04-16 2009-04-16 Recombinant fsh including alpha 2,3- and alpha 2,6-sialylation
EP14178729.1A EP2808340B1 (en) 2008-04-16 2009-04-16 Recombinant fsh including alpha 2,3- and alpha 2,6-sialylation
EP13193214.7A EP2722339A1 (en) 2008-04-16 2009-04-16 Recombinant fsh including alpha 2,3- and alpha 2,6-sialylation

Publications (1)

Publication Number Publication Date
NO2017025I1 true NO2017025I1 (no) 2017-06-06

Family

ID=39717519

Family Applications (4)

Application Number Title Priority Date Filing Date
NO2017025C NO2017025I1 (no) 2008-04-16 2017-06-06 Rekombinant FSH (rFSH) innbefattende alfa2,3-sialylering og alfa2,6-sialylering hvor 80% eller mer av den totale sialylering er alfa2,3-sialylering og hvor fra 5% til 20% av den totale sialylering er alfa2,6- sialylering, spesielt follitropin delta.
NO2017050C NO2017050I1 (no) 2008-04-25 2017-09-28 Rekombinant FSH (folikkel-stimulerende hormon)
NO2025006C NO2025006I1 (no) 2008-04-25 2025-01-16 Follitropin delta
NO2025032C NO2025032I1 (no) 2008-04-25 2025-07-14 Follitropin delta

Family Applications After (3)

Application Number Title Priority Date Filing Date
NO2017050C NO2017050I1 (no) 2008-04-25 2017-09-28 Rekombinant FSH (folikkel-stimulerende hormon)
NO2025006C NO2025006I1 (no) 2008-04-25 2025-01-16 Follitropin delta
NO2025032C NO2025032I1 (no) 2008-04-25 2025-07-14 Follitropin delta

Country Status (29)

Country Link
US (6) US8951967B2 (enExample)
EP (7) EP3144318B1 (enExample)
JP (7) JP2011519359A (enExample)
KR (5) KR20170110741A (enExample)
CN (3) CN102066414A (enExample)
AR (1) AR071479A1 (enExample)
AU (5) AU2009237479B2 (enExample)
BR (1) BRPI0910461B8 (enExample)
CA (1) CA2725257A1 (enExample)
CY (1) CY1115413T1 (enExample)
DK (6) DK3045471T3 (enExample)
ES (5) ES2629392T3 (enExample)
FI (4) FI4015527T3 (enExample)
FR (3) FR17C1020I2 (enExample)
HR (5) HRP20250313T1 (enExample)
HU (9) HUE071059T2 (enExample)
IL (2) IL208538A (enExample)
LT (8) LT3045471T (enExample)
MX (3) MX2010011343A (enExample)
NO (4) NO2017025I1 (enExample)
NZ (1) NZ588381A (enExample)
PL (6) PL3144318T3 (enExample)
PT (6) PT3098234T (enExample)
RU (3) RU2682270C2 (enExample)
SA (1) SA109300228B1 (enExample)
SI (6) SI2268666T1 (enExample)
TW (1) TWI488640B (enExample)
WO (1) WO2009127826A1 (enExample)
ZA (1) ZA201007373B (enExample)

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HUE025514T2 (en) 2010-09-29 2016-02-29 Ferring Bv Preparation for use in treating infertility
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US9757469B2 (en) 2011-03-31 2017-09-12 Ferring B.V. Pharmaceutical preparation
AR090095A1 (es) 2011-06-06 2014-10-22 Ferring Bv Preparacion farmaceutica que comprende hormona estimulante del foliculo recombinante
JO3092B1 (ar) 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
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ES2989511T3 (es) 2017-09-01 2024-11-26 Ferring Bv Composición para la estimulación ovárica controlada
EP4534145A3 (en) 2018-04-30 2025-07-02 Ferring B.V. Composition for controlled ovarian stimulation
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US20220380785A1 (en) * 2019-11-01 2022-12-01 The University Of British Columbia Compositions and methods for sialylated mucin-type o-glycosylation of therapeutic proteins
TW202237173A (zh) 2020-12-09 2022-10-01 荷蘭商菲林公司 用於受控的卵巢刺激之組成物及方法
EP4504236A1 (en) 2022-04-01 2025-02-12 Ferring B.V. Mixed protocol for treatment of infertility
JP2025516966A (ja) 2022-05-26 2025-05-30 フェリング ベスローテン フェンノートシャップ 男性の不妊症の治療のための組成物及び方法
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HUE025514T2 (en) 2010-09-29 2016-02-29 Ferring Bv Preparation for use in treating infertility
US9757469B2 (en) 2011-03-31 2017-09-12 Ferring B.V. Pharmaceutical preparation
AR090095A1 (es) 2011-06-06 2014-10-22 Ferring Bv Preparacion farmaceutica que comprende hormona estimulante del foliculo recombinante
JO3092B1 (ar) 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
EP3131571A1 (en) 2014-04-18 2017-02-22 Glycotope GmbH Controlled ovarian hyperstimulation with improved recombinant human follicle-stimulating hormone

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ES2468318T3 (es) 2014-06-16
EP2268666B1 (en) 2014-03-12
LT3045471T (lt) 2017-07-10
EP3144318A1 (en) 2017-03-22
SA109300228B1 (ar) 2014-04-08
EP3045471B1 (en) 2017-03-29
PL3045471T3 (pl) 2017-10-31
RU2537268C2 (ru) 2014-12-27
HUE033830T2 (en) 2018-01-29
LT2808340T (lt) 2016-11-10
CY1115413T1 (el) 2017-01-04
EP2722339A1 (en) 2014-04-23
TW200948378A (en) 2009-12-01
HUS2500029I1 (hu) 2025-07-28
FR17C1020I2 (fr) 2020-04-10
KR20190092608A (ko) 2019-08-07
HRP20241187T1 (hr) 2024-12-06
AU2017225020B2 (en) 2019-11-14
US9546204B2 (en) 2017-01-17
EP3144318B1 (en) 2020-09-23
US20150065695A1 (en) 2015-03-05
KR20160056960A (ko) 2016-05-20
SI2268666T1 (sl) 2014-07-31
JP7316905B2 (ja) 2023-07-28
SI3098234T1 (sl) 2024-10-30
AU2014203277B2 (en) 2017-04-06
RU2682270C2 (ru) 2019-03-18
CN105906703A (zh) 2016-08-31
US20110105398A1 (en) 2011-05-05
AU2017204259B2 (en) 2017-08-17
US11952407B2 (en) 2024-04-09
CA2725257A1 (en) 2009-10-22
LTPA2017029I1 (lt) 2017-10-10
MX348622B (es) 2017-06-22
FR25C1003I1 (fr) 2025-02-28
NO2017050I1 (no) 2017-09-28
KR20180095140A (ko) 2018-08-24
HUS1700036I1 (hu) 2017-10-30
SI4015527T1 (sl) 2025-05-30
PL2268666T3 (pl) 2014-08-29
FI3098234T3 (fi) 2024-10-31
ES2610277T3 (es) 2017-04-26
HRP20140535T1 (hr) 2014-07-18
HUE030652T2 (en) 2017-05-29
HUS2500008I1 (hu) 2025-02-28
JP6762916B2 (ja) 2020-09-30
RU2014141994A (ru) 2016-05-10
PT4015527T (pt) 2025-04-10
FR17C1020I1 (enExample) 2020-04-10
BRPI0910461A8 (pt) 2018-10-16
RU2014141994A3 (enExample) 2018-05-28
PT2268666E (pt) 2014-06-25
RU2745557C3 (ru) 2021-12-10
NO2025032I1 (no) 2025-07-14
HUS1700025I1 (hu) 2017-06-28
HK1199039A1 (en) 2015-06-19
FI4015527T3 (fi) 2025-04-29
LT3098234T (lt) 2024-09-10
PT3144318T (pt) 2020-11-04
ES2629392T3 (es) 2017-08-09
BRPI0910461B8 (pt) 2021-05-25
US9771407B2 (en) 2017-09-26
ES2989729T3 (es) 2024-11-27
AU2017225020A1 (en) 2017-09-28
NO2025006I1 (no) 2025-01-16
RU2745557C1 (ru) 2021-03-29
JP6486310B2 (ja) 2019-03-20
FR25C1025I1 (fr) 2025-09-19
NZ588381A (en) 2012-05-25
AU2014203277A1 (en) 2014-07-24
EP2268666A1 (en) 2011-01-05
JP2011519359A (ja) 2011-07-07
RU2010141908A (ru) 2012-05-27
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BRPI0910461B1 (pt) 2021-02-23
DK3144318T3 (da) 2020-12-07
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AU2017204258B2 (en) 2017-08-17
KR102108377B1 (ko) 2020-05-08
HRP20250313T1 (hr) 2025-05-09
HK1146284A1 (en) 2011-05-20
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ZA201007373B (en) 2011-06-29
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CN102066414A (zh) 2011-05-18
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PL3144318T3 (pl) 2021-02-08
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DK4015527T3 (da) 2025-04-14
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WO2009127826A1 (en) 2009-10-22
IL230571A (en) 2015-11-30
LTPA2025525I1 (enExample) 2025-07-25
PL2808340T3 (pl) 2017-02-28
US20240327487A1 (en) 2024-10-03
MX355457B (es) 2018-04-19
PT3045471T (pt) 2017-06-14
PL3098234T3 (pl) 2025-01-07
MX2010011343A (es) 2011-01-20
PL4015527T3 (pl) 2025-05-26
PT2808340T (pt) 2016-11-21
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JP2024038000A (ja) 2024-03-19
SI2808340T1 (sl) 2016-12-30
AR071479A1 (es) 2010-06-23
IL208538A0 (en) 2010-12-30
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