LTPA2017018I1 - Rekombinantinis FSH, įskaitant alfa 2,3- ir alfa 2,6-sialilinimą - Google Patents

Rekombinantinis FSH, įskaitant alfa 2,3- ir alfa 2,6-sialilinimą

Info

Publication number
LTPA2017018I1
LTPA2017018I1 LTPA2017018C LTPA2017018C LTPA2017018I1 LT PA2017018 I1 LTPA2017018 I1 LT PA2017018I1 LT PA2017018 C LTPA2017018 C LT PA2017018C LT PA2017018 C LTPA2017018 C LT PA2017018C LT PA2017018 I1 LTPA2017018 I1 LT PA2017018I1
Authority
LT
Lithuania
Prior art keywords
alpha
sialylation
recombinant fsh
fsh including
including alpha
Prior art date
Application number
LTPA2017018C
Other languages
English (en)
Original Assignee
Ferring B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39717519&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LTPA2017018(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferring B.V. filed Critical Ferring B.V.
Publication of LTPA2017018I1 publication Critical patent/LTPA2017018I1/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C12Y204/99006—N-Acetyllactosaminide alpha-2,3-sialyltransferase (2.4.99.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LTPA2017018C 2008-04-16 2017-06-05 Rekombinantinis FSH, įskaitant alfa 2,3- ir alfa 2,6-sialilinimą LTPA2017018I1 (lt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4542408P 2008-04-16 2008-04-16
EP08251528 2008-04-25
EP09733497.3A EP2268666B1 (en) 2008-04-16 2009-04-16 Recombinant fsh including alpha 2,3- and alpha 2,6-sialylation
EP14178729.1A EP2808340B1 (en) 2008-04-16 2009-04-16 Recombinant fsh including alpha 2,3- and alpha 2,6-sialylation
EP13193214.7A EP2722339A1 (en) 2008-04-16 2009-04-16 Recombinant fsh including alpha 2,3- and alpha 2,6-sialylation

Publications (1)

Publication Number Publication Date
LTPA2017018I1 true LTPA2017018I1 (lt) 2017-06-26

Family

ID=39717519

Family Applications (4)

Application Number Title Priority Date Filing Date
LTEP16158141.8T LT3045471T (lt) 2008-04-16 2009-04-16 Rekombinantinis fsh, įskaitant alfa 2,3- ir alfa 2,6-sialilinimą
LTEP14178729.1T LT2808340T (lt) 2008-04-16 2009-04-16 Rekombinantinis fsh, įskaitant alfa 2,3- ir alfa 2,6-sialilinimą
LTPA2017018C LTPA2017018I1 (lt) 2008-04-16 2017-06-05 Rekombinantinis FSH, įskaitant alfa 2,3- ir alfa 2,6-sialilinimą
LTPA2017029C LTPA2017029I1 (lt) 2008-04-16 2017-09-27 Rekombinantinis FSH, įskaitant alfa 2,3- ir alfa 2,6-sialilinimą

Family Applications Before (2)

Application Number Title Priority Date Filing Date
LTEP16158141.8T LT3045471T (lt) 2008-04-16 2009-04-16 Rekombinantinis fsh, įskaitant alfa 2,3- ir alfa 2,6-sialilinimą
LTEP14178729.1T LT2808340T (lt) 2008-04-16 2009-04-16 Rekombinantinis fsh, įskaitant alfa 2,3- ir alfa 2,6-sialilinimą

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTPA2017029C LTPA2017029I1 (lt) 2008-04-16 2017-09-27 Rekombinantinis FSH, įskaitant alfa 2,3- ir alfa 2,6-sialilinimą

Country Status (29)

Country Link
US (5) US8951967B2 (lt)
EP (7) EP3045471B1 (lt)
JP (7) JP2011519359A (lt)
KR (5) KR20180095140A (lt)
CN (3) CN102066414A (lt)
AR (1) AR071479A1 (lt)
AU (5) AU2009237479B2 (lt)
BR (1) BRPI0910461B8 (lt)
CA (1) CA2725257A1 (lt)
CY (1) CY1115413T1 (lt)
DK (4) DK3144318T3 (lt)
ES (3) ES2610277T3 (lt)
FR (1) FR17C1020I2 (lt)
HK (2) HK1146284A1 (lt)
HR (3) HRP20140535T1 (lt)
HU (5) HUE030652T4 (lt)
IL (2) IL208538A (lt)
LT (4) LT3045471T (lt)
MX (3) MX2010011343A (lt)
NO (2) NO2017025I1 (lt)
NZ (1) NZ588381A (lt)
PL (4) PL2268666T3 (lt)
PT (4) PT2808340T (lt)
RU (3) RU2537268C2 (lt)
SA (1) SA109300228B1 (lt)
SI (4) SI3045471T1 (lt)
TW (1) TWI488640B (lt)
WO (1) WO2009127826A1 (lt)
ZA (1) ZA201007373B (lt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI488640B (zh) 2008-04-16 2015-06-21 Ferring Int Ct Sa 藥學製劑
TWI532495B (zh) 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
EP2417982A1 (en) 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
WO2012016576A1 (en) 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone
ES2547233T5 (es) 2010-09-29 2024-03-27 Ferring Bv Composición para su uso en el tratamiento de la esterilidad
WO2012050175A1 (ja) 2010-10-15 2012-04-19 日本ケミカルリサーチ株式会社 糖鎖の非還元末端がマンノース残基である糖蛋白質の製造方法
US9757469B2 (en) 2011-03-31 2017-09-12 Ferring B.V. Pharmaceutical preparation
EP2717904A1 (en) 2011-06-06 2014-04-16 Ferring BV Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar) * 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
AU2012340501A1 (en) * 2011-12-19 2013-07-11 Grifols, S.A. Compositions, methods, and kits for preparing sialylated recombinant proteins
WO2013161958A1 (ja) * 2012-04-27 2013-10-31 日本ケミカルリサーチ株式会社 新規な発現ベクター
EP2824176A1 (en) * 2013-07-11 2015-01-14 Siamed'xpress Methods for producing sialylated therapeutic proteins
JP6652334B2 (ja) 2014-05-31 2020-02-19 Ｊｃｒファーマ株式会社 ウリジンとｎ−アセチル−ｄ−マンノサミンとを含有する培地
EP3237608B1 (en) * 2014-12-22 2019-10-09 F. Hoffmann-La Roche AG Cmp-dependent sialidase activity
DK3662925T3 (da) 2015-04-17 2021-06-28 Ferring Bv Sammensætning, der omfatter fsh, til behandling af infertilitet
RU2719468C2 (ru) 2015-06-26 2020-04-17 Ферринг Б.В. Способы очистки и/или вирусной инактивации
EP3205719A1 (en) * 2016-02-15 2017-08-16 CEVEC Pharmaceuticals GmbH Cell lines for producing recombinant glycoproteins with di-antennary n-glycans, methods using the same, and recombinant glycoproteins
GB201603280D0 (en) 2016-02-24 2016-04-13 Ferring Bv Stable liquid gonadotropin formulation
EP3382014A1 (en) 2017-03-29 2018-10-03 CEVEC Pharmaceuticals GmbH Recombinant glycoproteins with reduced antennary fucosylation
MX2020002235A (es) 2017-09-01 2020-07-20 Ferring Bv Composicion para la estimulacion ovarica controlada.
TW201945024A (zh) 2018-04-30 2019-12-01 荷蘭商菲林公司 用於經控制之卵巢刺激的組成物
TW202027780A (zh) 2018-10-17 2020-08-01 荷蘭商菲林公司 用於控制性卵巢刺激之組成物及方法
WO2021081670A1 (en) * 2019-11-01 2021-05-06 The University Of British Columbia Compositions and methods for sialylated mucin-type o-glycosylation of therapeutic proteins
TW202237173A (zh) 2020-12-09 2022-10-01 荷蘭商菲林公司 用於受控的卵巢刺激之組成物及方法
WO2023186331A1 (en) 2022-04-01 2023-10-05 Ferring B.V. Mixed protocol for treatment of infertility
WO2023227761A1 (en) 2022-05-26 2023-11-30 Ferring B.V. Compositions and methods for treatment of infertility in males
WO2024008971A1 (en) 2022-07-08 2024-01-11 Ferring B.V. Compositions and methods for intrauterine insemination (iui)

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1206302B (it) 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
US5541083A (en) 1989-10-24 1996-07-30 The Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
KR100449181B1 (ko) 1995-06-15 2005-01-24 크루셀 홀란드 비.브이. 유전자요법에사용할수있는사람의재조합아데노바이러스패키징시스템
JP3559652B2 (ja) * 1996-06-25 2004-09-02 グローリー工業株式会社 売上精算システムの管理装置
TW518235B (en) * 1997-01-15 2003-01-21 Akzo Nobel Nv A gonadotropin-containing pharmaceutical composition with improved stability on prolong storage
JP2001507215A (ja) 1997-01-16 2001-06-05 サイテル コーポレイション 組換え糖タンパク質のインビトロでの実用的なシアリル化
JPH1111665A (ja) 1997-06-28 1999-01-19 Shibuya Kogyo Co Ltd 無菌エア搬送コンベヤ装置
TWI235158B (en) * 1997-09-01 2005-07-01 Kirin Brewery Human thrombopoietin produced by human established cell lines, processes foe preparing the same, and pharmaceutical composition comprising the same
EP1176976B2 (en) 1999-05-07 2015-10-21 Laboratoires Serono SA Use of lh administered in mid- or late-follicular phase for the treatment of anovulatory women
JP2002011665A (ja) 2000-06-28 2002-01-15 Sintokogio Ltd ショットブラスト装置モニタシステム
IL140110A0 (en) 2000-12-05 2002-02-10 Applied Research Systems Improvement of homogeneity and secretion of recombinant proteins in mammalian systems
MEP38608A (en) * 2001-10-22 2011-02-10 Merck Serono Sa Gonadotrophins for folliculogenesis
EA012340B1 (ru) 2001-10-29 2009-10-30 Круселл Холланд Б.В. Способ получения гликозилированной белковой молекулы, содержащей структуру lewis x, и/или сиалил-lewis x, и/или lacdinac
NZ533124A (en) 2001-12-07 2005-11-25 Crucell Holland B Production of viruses, viral isolates and vaccines
US20040248784A1 (en) * 2003-06-03 2004-12-09 Marco Filicori Unitary combinations of FSH and hCG
EP1694351A2 (en) * 2003-12-03 2006-08-30 Neose Technologies, Inc. Glycopegylated follicle stimulating hormone
US8431355B2 (en) 2004-02-04 2013-04-30 Universite De Provence Aix-Marseille 1 Process for screening glycoform-specific antibodies
CA2557725C (en) 2004-02-13 2015-06-30 Glycotope Gmbh Highly active glycoproteins-process conditions and an efficient method for their production
TWI488640B (zh) 2008-04-16 2015-06-21 Ferring Int Ct Sa 藥學製劑
TWI532495B (zh) 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
EP2417982A1 (en) 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
WO2012016575A1 (en) 2010-08-03 2012-02-09 King Saud University Stoma coat
WO2012016576A1 (en) 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone
ES2547233T5 (es) 2010-09-29 2024-03-27 Ferring Bv Composición para su uso en el tratamiento de la esterilidad
US9757469B2 (en) 2011-03-31 2017-09-12 Ferring B.V. Pharmaceutical preparation
EP2717904A1 (en) 2011-06-06 2014-04-16 Ferring BV Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar) 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
US20170035854A1 (en) 2014-04-18 2017-02-09 Glycotope Gmbh Controlled ovarian hyperstimulation with improved recombinant human follicle-stimulating hormone

Also Published As

Publication number Publication date
SI3045471T1 (sl) 2017-07-31
EP3144318B1 (en) 2020-09-23
US9546204B2 (en) 2017-01-17
US20150065695A1 (en) 2015-03-05
HUS1700024I1 (hu) 2017-06-28
US20110105398A1 (en) 2011-05-05
JP6486310B2 (ja) 2019-03-20
AU2017204259B2 (en) 2017-08-17
PL2808340T3 (pl) 2017-02-28
US20180079794A1 (en) 2018-03-22
FR17C1020I2 (fr) 2020-04-10
HK1199039A1 (en) 2015-06-19
PT3045471T (pt) 2017-06-14
EP2808340A1 (en) 2014-12-03
EP4015527A1 (en) 2022-06-22
HRP20161520T1 (hr) 2016-12-30
IL208538A (en) 2014-03-31
NZ588381A (en) 2012-05-25
LT2808340T (lt) 2016-11-10
US9771407B2 (en) 2017-09-26
RU2537268C2 (ru) 2014-12-27
EP2808340B1 (en) 2016-08-17
IL230571A (en) 2015-11-30
US10995128B2 (en) 2021-05-04
WO2009127826A1 (en) 2009-10-22
US20210332099A1 (en) 2021-10-28
TW200948378A (en) 2009-12-01
BRPI0910461B1 (pt) 2021-02-23
KR20160056960A (ko) 2016-05-20
SI2808340T1 (sl) 2016-12-30
JP2018021037A (ja) 2018-02-08
NO2017025I1 (no) 2017-06-06
US11952407B2 (en) 2024-04-09
AU2017225020A1 (en) 2017-09-28
KR20190092608A (ko) 2019-08-07
ZA201007373B (en) 2011-06-29
PT2268666E (pt) 2014-06-25
DK3045471T3 (en) 2017-06-26
AU2017204258A1 (en) 2017-07-20
RU2014141994A (ru) 2016-05-10
ES2629392T3 (es) 2017-08-09
AU2017225020B2 (en) 2019-11-14
TWI488640B (zh) 2015-06-21
KR20170110741A (ko) 2017-10-11
EP2722339A1 (en) 2014-04-23
RU2745557C3 (ru) 2021-12-10
PT2808340T (pt) 2016-11-21
JP7316905B2 (ja) 2023-07-28
HUE030652T4 (en) 2017-09-28
DK2268666T3 (da) 2014-05-12
PT3144318T (pt) 2020-11-04
CA2725257A1 (en) 2009-10-22
SI2268666T1 (sl) 2014-07-31
JP2020040956A (ja) 2020-03-19
JP2015120696A (ja) 2015-07-02
JP6762916B2 (ja) 2020-09-30
AU2009237479A1 (en) 2009-10-22
RU2014141994A3 (lt) 2018-05-28
MX355457B (es) 2018-04-19
EP2268666B1 (en) 2014-03-12
EP3098234A1 (en) 2016-11-30
EP3045471A1 (en) 2016-07-20
JP2024038000A (ja) 2024-03-19
CY1115413T1 (el) 2017-01-04
AU2014203277A1 (en) 2014-07-24
RU2745557C1 (ru) 2021-03-29
PL2268666T3 (pl) 2014-08-29
JP2017060476A (ja) 2017-03-30
ES2468318T3 (es) 2014-06-16
JP2022031652A (ja) 2022-02-22
HRP20170958T1 (hr) 2017-09-22
RU2682270C2 (ru) 2019-03-18
AU2014203277B2 (en) 2017-04-06
SA109300228B1 (ar) 2014-04-08
LT3045471T (lt) 2017-07-10
MX348622B (es) 2017-06-22
NO2017050I1 (no) 2017-09-28
HK1146284A1 (en) 2011-05-20
EP3045471B1 (en) 2017-03-29
HUE030652T2 (en) 2017-05-29
CN105906702A (zh) 2016-08-31
EP3144318A1 (en) 2017-03-22
KR20110005863A (ko) 2011-01-19
LTPA2017029I1 (lt) 2017-10-10
SI3144318T1 (sl) 2020-12-31
US20160347811A1 (en) 2016-12-01
KR102108377B1 (ko) 2020-05-08
ES2610277T3 (es) 2017-04-26
HRP20140535T1 (hr) 2014-07-18
KR101622944B1 (ko) 2016-05-23
PL3045471T3 (pl) 2017-10-31
BRPI0910461A2 (pt) 2018-03-27
AU2014203277C1 (en) 2017-07-27
AU2009237479B2 (en) 2014-05-15
AR071479A1 (es) 2010-06-23
AU2017204258B2 (en) 2017-08-17
RU2010141908A (ru) 2012-05-27
DK2808340T3 (en) 2016-12-05
US8951967B2 (en) 2015-02-10
MX2010011343A (es) 2011-01-20
JP2011519359A (ja) 2011-07-07
PL3144318T3 (pl) 2021-02-08
CN105906703A (zh) 2016-08-31
EP2268666A1 (en) 2011-01-05
AU2017204259A1 (en) 2017-07-20
HUS1700036I1 (hu) 2017-10-30
IL208538A0 (en) 2010-12-30
CN102066414A (zh) 2011-05-18
FR17C1020I1 (lt) 2020-04-10
HUE033830T2 (en) 2018-01-29
DK3144318T3 (da) 2020-12-07
BRPI0910461B8 (pt) 2021-05-25
HUS1700025I1 (hu) 2017-06-28
BRPI0910461A8 (pt) 2018-10-16
KR20180095140A (ko) 2018-08-24

Similar Documents

Publication Publication Date Title
LTPA2017029I1 (lt) Rekombinantinis FSH, įskaitant alfa 2,3- ir alfa 2,6-sialilinimą
BRPI0917258A2 (pt) composição reforçadora, e, composição detergente
BRPI0918472A2 (pt) composto 2,4-diaminopirimidina
BRPI0911743A2 (pt) "peptídeo"
UY33125A (es) Diaza-espiro-[5,5]-undecanos
BRPI0916129A2 (pt) "reforço"
GB0807206D0 (en) I.C.E. cylinder
FI20080124A0 (fi) Läheis-Josephson-ilmaisin
FI20080585A (fi) Telkimekanismi
FI20085362A (fi) Kahmari
BRPI1014211A2 (pt) "composição."
HUE051918T2 (hu) Alfa 2,3- és alfa 2,6-szialilációt tartalmazó rekombináns FSH
FI20080380A0 (fi) Liikeanalysaattori
CN300893078S (zh) 瓶子(1)
TH128836B (th) การปรับปรุงผลิตภัณฑ์ที่ใช้กับเส้นใยผ้าให้ดีขึ้น
TH105749B (th) ไทรซับสทิทิวเทด 1,2,4 ไทรแอโซล
BRPI0908197A2 (pt) antígenos recombinantes
FI7964U1 (fi) Liitoskappale
FI8353U1 (fi) Liitoskappale
UA19151S (uk) Баровакуумний автоклав «маркіс»
SE0801220L (sv) Hurry 1.3