SI3045471T1 - Rekombinantni FSH, ki vključuje alfa 2,3 in alfa 2,6-sialilacijo - Google Patents

Rekombinantni FSH, ki vključuje alfa 2,3 in alfa 2,6-sialilacijo

Info

Publication number
SI3045471T1
SI3045471T1 SI200931670A SI200931670A SI3045471T1 SI 3045471 T1 SI3045471 T1 SI 3045471T1 SI 200931670 A SI200931670 A SI 200931670A SI 200931670 A SI200931670 A SI 200931670A SI 3045471 T1 SI3045471 T1 SI 3045471T1
Authority
SI
Slovenia
Prior art keywords
alpha
sialylation
recombinant fsh
fsh including
including alpha
Prior art date
Application number
SI200931670A
Other languages
English (en)
Inventor
Ian Cottingham
Daniel Plaksin
Richard Boyd White
Original Assignee
Ferring B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39717519&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI3045471(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferring B.V. filed Critical Ferring B.V.
Publication of SI3045471T1 publication Critical patent/SI3045471T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C12Y204/99006—N-Acetyllactosaminide alpha-2,3-sialyltransferase (2.4.99.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
SI200931670A 2008-04-16 2009-04-16 Rekombinantni FSH, ki vključuje alfa 2,3 in alfa 2,6-sialilacijo SI3045471T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4542408P 2008-04-16 2008-04-16
EP08251528 2008-04-25
EP16158141.8A EP3045471B1 (en) 2008-04-16 2009-04-16 Recombinant fsh including alpha 2,3- and alpha 2,6-sialylation

Publications (1)

Publication Number Publication Date
SI3045471T1 true SI3045471T1 (sl) 2017-07-31

Family

ID=39717519

Family Applications (4)

Application Number Title Priority Date Filing Date
SI200930931T SI2268666T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo
SI200931670A SI3045471T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vključuje alfa 2,3 in alfa 2,6-sialilacijo
SI200931547A SI2808340T1 (sl) 2008-04-16 2009-04-16 Rekombinirani FSH, ki vključuje alfa 2,3- in alfa 2,6-sialilacijo
SI200932094T SI3144318T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI200930931T SI2268666T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo

Family Applications After (2)

Application Number Title Priority Date Filing Date
SI200931547A SI2808340T1 (sl) 2008-04-16 2009-04-16 Rekombinirani FSH, ki vključuje alfa 2,3- in alfa 2,6-sialilacijo
SI200932094T SI3144318T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo

Country Status (28)

Country Link
US (5) US8951967B2 (sl)
EP (7) EP4015527A1 (sl)
JP (7) JP2011519359A (sl)
KR (5) KR20170110741A (sl)
CN (3) CN102066414A (sl)
AR (1) AR071479A1 (sl)
AU (5) AU2009237479B2 (sl)
BR (1) BRPI0910461B8 (sl)
CA (1) CA2725257A1 (sl)
CY (1) CY1115413T1 (sl)
DK (4) DK2268666T3 (sl)
ES (3) ES2468318T3 (sl)
HK (2) HK1146284A1 (sl)
HR (3) HRP20140535T1 (sl)
HU (5) HUE030652T4 (sl)
IL (2) IL208538A (sl)
LT (4) LT3045471T (sl)
MX (3) MX348622B (sl)
NO (2) NO2017025I1 (sl)
NZ (1) NZ588381A (sl)
PL (4) PL2808340T3 (sl)
PT (4) PT3144318T (sl)
RU (3) RU2537268C2 (sl)
SA (1) SA109300228B1 (sl)
SI (4) SI2268666T1 (sl)
TW (1) TWI488640B (sl)
WO (1) WO2009127826A1 (sl)
ZA (1) ZA201007373B (sl)

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TWI604850B (zh) 2009-10-05 2017-11-11 菲瑞茵國際中心股份有限公司 藥學製劑
EP2417982A1 (en) 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
WO2012016576A1 (en) * 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone
SI2621517T2 (sl) 2010-09-29 2023-11-30 Ferring B.V. Sestavek za uporabo pri zdravljenju neplodnosti
CN103154243A (zh) 2010-10-15 2013-06-12 日本化学研究株式会社 糖链的非还原末端为甘露糖残基的糖蛋白的制造方法
CN103619358B (zh) 2011-03-31 2017-02-15 辉凌公司 药物制剂
AR090095A1 (es) 2011-06-06 2014-10-22 Ferring Bv Preparacion farmaceutica que comprende hormona estimulante del foliculo recombinante
JO3092B1 (ar) * 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
WO2013093760A2 (en) * 2011-12-19 2013-06-27 Grifols, S.A. Compositions, methods, and kits for preparing sialylated recombinant proteins
JP6279466B2 (ja) * 2012-04-27 2018-02-14 Ｊｃｒファーマ株式会社 新規な発現ベクター
EP2824176A1 (en) * 2013-07-11 2015-01-14 Siamed'xpress Methods for producing sialylated therapeutic proteins
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JP2018500934A (ja) * 2014-12-22 2018-01-18 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｃｍｐ依存性シアリダーゼ活性
AU2016247498B2 (en) 2015-04-17 2021-06-03 Ferring B.V. Composition for treatment of infertility
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EP3382014A1 (en) * 2017-03-29 2018-10-03 CEVEC Pharmaceuticals GmbH Recombinant glycoproteins with reduced antennary fucosylation
CN111050787A (zh) 2017-09-01 2020-04-21 辉凌公司 用于受控的卵巢刺激的组合物
JP2021522268A (ja) 2018-04-30 2021-08-30 フェリング ベスローテン フェンノートシャップ 制御された卵巣刺激のための組成物
TW202027780A (zh) 2018-10-17 2020-08-01 荷蘭商菲林公司 用於控制性卵巢刺激之組成物及方法
WO2021081670A1 (en) * 2019-11-01 2021-05-06 The University Of British Columbia Compositions and methods for sialylated mucin-type o-glycosylation of therapeutic proteins
TW202237173A (zh) 2020-12-09 2022-10-01 荷蘭商菲林公司 用於受控的卵巢刺激之組成物及方法
WO2023186331A1 (en) 2022-04-01 2023-10-05 Ferring B.V. Mixed protocol for treatment of infertility
WO2023227761A1 (en) 2022-05-26 2023-11-30 Ferring B.V. Compositions and methods for treatment of infertility in males
WO2024008971A1 (en) 2022-07-08 2024-01-11 Ferring B.V. Compositions and methods for intrauterine insemination (iui)

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WO2012016576A1 (en) 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone
SI2621517T2 (sl) 2010-09-29 2023-11-30 Ferring B.V. Sestavek za uporabo pri zdravljenju neplodnosti
CN103619358B (zh) 2011-03-31 2017-02-15 辉凌公司 药物制剂
AR090095A1 (es) 2011-06-06 2014-10-22 Ferring Bv Preparacion farmaceutica que comprende hormona estimulante del foliculo recombinante
JO3092B1 (ar) 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
BR112016023668A2 (pt) 2014-04-18 2017-10-17 Glycotope Gmbh hiperestimulação ovariana controlada com hormônio de estimulação de folículo humano recombinante aperfeiçoado

Also Published As

Publication number Publication date
IL208538A0 (en) 2010-12-30
PL2808340T3 (pl) 2017-02-28
SA109300228B1 (ar) 2014-04-08
BRPI0910461B1 (pt) 2021-02-23
KR102108377B1 (ko) 2020-05-08
JP2011519359A (ja) 2011-07-07
NZ588381A (en) 2012-05-25
AR071479A1 (es) 2010-06-23
US11952407B2 (en) 2024-04-09
BRPI0910461A2 (pt) 2018-03-27
HK1199039A1 (en) 2015-06-19
US9546204B2 (en) 2017-01-17
EP3144318A1 (en) 2017-03-22
EP2268666A1 (en) 2011-01-05
KR101622944B1 (ko) 2016-05-23
JP2015120696A (ja) 2015-07-02
ES2610277T3 (es) 2017-04-26
US9771407B2 (en) 2017-09-26
AU2017225020A1 (en) 2017-09-28
RU2745557C1 (ru) 2021-03-29
WO2009127826A1 (en) 2009-10-22
CA2725257A1 (en) 2009-10-22
AU2017204259A1 (en) 2017-07-20
JP6762916B2 (ja) 2020-09-30
US20210332099A1 (en) 2021-10-28
EP3045471A1 (en) 2016-07-20
US20110105398A1 (en) 2011-05-05
DK3144318T3 (da) 2020-12-07
TWI488640B (zh) 2015-06-21
EP2808340B1 (en) 2016-08-17
CY1115413T1 (el) 2017-01-04
ZA201007373B (en) 2011-06-29
IL208538A (en) 2014-03-31
NO2017025I1 (no) 2017-06-06
HRP20161520T1 (hr) 2016-12-30
JP2024038000A (ja) 2024-03-19
KR20170110741A (ko) 2017-10-11
HRP20140535T1 (hr) 2014-07-18
ES2468318T3 (es) 2014-06-16
JP2017060476A (ja) 2017-03-30
AU2017204258B2 (en) 2017-08-17
LT3045471T (lt) 2017-07-10
EP3098234A1 (en) 2016-11-30
EP3045471B1 (en) 2017-03-29
HUS1700025I1 (hu) 2017-06-28
CN105906702A (zh) 2016-08-31
AU2014203277A1 (en) 2014-07-24
HUE030652T2 (en) 2017-05-29
HRP20170958T1 (hr) 2017-09-22
LTPA2017029I1 (lt) 2017-10-10
CN105906703A (zh) 2016-08-31
JP2020040956A (ja) 2020-03-19
RU2537268C2 (ru) 2014-12-27
PL3144318T3 (pl) 2021-02-08
PL3045471T3 (pl) 2017-10-31
EP4015527A1 (en) 2022-06-22
AU2014203277C1 (en) 2017-07-27
AU2017225020B2 (en) 2019-11-14
DK2808340T3 (en) 2016-12-05
RU2682270C2 (ru) 2019-03-18
PT2808340T (pt) 2016-11-21
EP3144318B1 (en) 2020-09-23
DK2268666T3 (da) 2014-05-12
HK1146284A1 (en) 2011-05-20
HUS1700036I1 (hu) 2017-10-30
US10995128B2 (en) 2021-05-04
CN102066414A (zh) 2011-05-18
JP6486310B2 (ja) 2019-03-20
NO2017050I1 (no) 2017-09-28
US20180079794A1 (en) 2018-03-22
TW200948378A (en) 2009-12-01
MX355457B (es) 2018-04-19
RU2014141994A (ru) 2016-05-10
EP2808340A1 (en) 2014-12-03
HUS1700024I1 (hu) 2017-06-28
PT3144318T (pt) 2020-11-04
EP2268666B1 (en) 2014-03-12
US20160347811A1 (en) 2016-12-01
LT2808340T (lt) 2016-11-10
KR20190092608A (ko) 2019-08-07
JP2018021037A (ja) 2018-02-08
PT2268666E (pt) 2014-06-25
US8951967B2 (en) 2015-02-10
US20150065695A1 (en) 2015-03-05
SI2808340T1 (sl) 2016-12-30
HUE030652T4 (en) 2017-09-28
AU2009237479B2 (en) 2014-05-15
BRPI0910461B8 (pt) 2021-05-25
JP7316905B2 (ja) 2023-07-28
KR20180095140A (ko) 2018-08-24
AU2014203277B2 (en) 2017-04-06
AU2009237479A1 (en) 2009-10-22
MX2010011343A (es) 2011-01-20
DK3045471T3 (en) 2017-06-26
HUE033830T2 (en) 2018-01-29
RU2010141908A (ru) 2012-05-27
EP2722339A1 (en) 2014-04-23
AU2017204258A1 (en) 2017-07-20
JP2022031652A (ja) 2022-02-22
KR20160056960A (ko) 2016-05-20
MX348622B (es) 2017-06-22
RU2745557C3 (ru) 2021-12-10
LTPA2017018I1 (lt) 2017-06-26
SI3144318T1 (sl) 2020-12-31
IL230571A (en) 2015-11-30
KR20110005863A (ko) 2011-01-19
RU2014141994A3 (sl) 2018-05-28
ES2629392T3 (es) 2017-08-09
SI2268666T1 (sl) 2014-07-31
AU2017204259B2 (en) 2017-08-17
PL2268666T3 (pl) 2014-08-29
BRPI0910461A8 (pt) 2018-10-16
PT3045471T (pt) 2017-06-14

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