NO20064631L - Konjugater av hydroksyalkylstivelse og et protein fremstilt ved reduktiv aminering - Google Patents
Konjugater av hydroksyalkylstivelse og et protein fremstilt ved reduktiv amineringInfo
- Publication number
- NO20064631L NO20064631L NO20064631A NO20064631A NO20064631L NO 20064631 L NO20064631 L NO 20064631L NO 20064631 A NO20064631 A NO 20064631A NO 20064631 A NO20064631 A NO 20064631A NO 20064631 L NO20064631 L NO 20064631L
- Authority
- NO
- Norway
- Prior art keywords
- conjugates
- reductive amination
- hydroxyalkyl starch
- protein produced
- hydroxyalkyl
- Prior art date
Links
- 229920002472 Starch Polymers 0.000 title abstract 3
- 125000002768 hydroxyalkyl group Chemical group 0.000 title abstract 3
- 235000019698 starch Nutrition 0.000 title abstract 3
- 239000008107 starch Substances 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 238000006268 reductive amination reaction Methods 0.000 title abstract 2
- 229920001612 Hydroxyethyl starch Polymers 0.000 abstract 1
- 125000003172 aldehyde group Chemical group 0.000 abstract 1
- 125000001976 hemiacetal group Chemical group 0.000 abstract 1
- 229940050526 hydroxyethylstarch Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
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- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
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- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/003—Crosslinking of starch
- C08B31/006—Crosslinking of derivatives of starch
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- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/08—Ethers
- C08B31/12—Ethers having alkyl or cycloalkyl radicals substituted by heteroatoms, e.g. hydroxyalkyl or carboxyalkyl starch
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- C—CHEMISTRY; METALLURGY
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- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
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- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/18—Oxidised starch
- C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55221704P | 2004-03-11 | 2004-03-11 | |
EP04005855 | 2004-03-11 | ||
PCT/EP2005/002653 WO2005092928A1 (en) | 2004-03-11 | 2005-03-11 | Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20064631L true NO20064631L (no) | 2006-12-11 |
Family
ID=34924481
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20064631A NO20064631L (no) | 2004-03-11 | 2006-10-10 | Konjugater av hydroksyalkylstivelse og et protein fremstilt ved reduktiv aminering |
Country Status (17)
Country | Link |
---|---|
US (1) | US8287850B2 (pt) |
EP (2) | EP1725589A1 (pt) |
JP (1) | JP5191729B2 (pt) |
KR (1) | KR101186821B1 (pt) |
CN (2) | CN1946742A (pt) |
AR (1) | AR048035A1 (pt) |
AU (1) | AU2005225513B2 (pt) |
BR (1) | BRPI0508607A (pt) |
CA (1) | CA2558738C (pt) |
DE (1) | DE202005021885U1 (pt) |
EA (1) | EA010501B1 (pt) |
IL (1) | IL177730A (pt) |
NO (1) | NO20064631L (pt) |
SG (1) | SG151261A1 (pt) |
TW (1) | TWI417303B (pt) |
WO (1) | WO2005092928A1 (pt) |
ZA (1) | ZA200607251B (pt) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10209822A1 (de) | 2002-03-06 | 2003-09-25 | Biotechnologie Ges Mittelhesse | Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid |
DE10209821A1 (de) | 2002-03-06 | 2003-09-25 | Biotechnologie Ges Mittelhesse | Kopplung von Proteinen an ein modifiziertes Polysaccharid |
RU2329274C2 (ru) | 2002-09-11 | 2008-07-20 | Фрезениус Каби Дойчланд Гмбх | Способ получения производных гидроксиалкилкрахмала |
SG145746A1 (en) * | 2003-08-08 | 2008-09-29 | Fresenius Kabi De Gmbh | Conjugates of hydroxyalkyl starch and g-csf |
WO2005014655A2 (en) * | 2003-08-08 | 2005-02-17 | Fresenius Kabi Deutschland Gmbh | Conjugates of hydroxyalkyl starch and a protein |
EP1732609B1 (en) * | 2004-03-11 | 2012-07-11 | Fresenius Kabi Deutschland GmbH | Conjugates of hydroxyalkyl starch and a protein |
TWI417303B (zh) | 2004-03-11 | 2013-12-01 | Fresenius Kabi De Gmbh | 經由還原胺化作用製得之羥烷基澱粉及蛋白質的接合物 |
KR20070110902A (ko) * | 2005-03-11 | 2007-11-20 | 프레제니우스 카비 도이치란트 게엠베하 | 비활성 출발 물질로부터 생물활성 당단백질의 생산 |
EP1762250A1 (en) * | 2005-09-12 | 2007-03-14 | Fresenius Kabi Deutschland GmbH | Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine |
WO2008012525A1 (en) * | 2006-07-25 | 2008-01-31 | Lipoxen Technologies Limited | Derivatisation of granulocyte colony-stimulating factor |
JP5570988B2 (ja) | 2007-08-27 | 2014-08-13 | ラティオファーム ゲーエムベーハー | G−csf結合体の液体調製物 |
EP2070951A1 (en) | 2007-12-14 | 2009-06-17 | Fresenius Kabi Deutschland GmbH | Method for producing a hydroxyalkyl starch derivatives with two linkers |
EP2070950A1 (en) | 2007-12-14 | 2009-06-17 | Fresenius Kabi Deutschland GmbH | Hydroxyalkyl starch derivatives and process for their preparation |
US20090176708A1 (en) * | 2007-12-27 | 2009-07-09 | Peter Turecek | Chemically modified factor ix |
EP2274331B1 (en) | 2008-05-02 | 2013-11-06 | Novartis AG | Improved fibronectin-based binding molecules and uses thereof |
RU2010149797A (ru) * | 2008-05-06 | 2012-06-20 | Октафарма АГ (CH) | Комплекс |
GB0811743D0 (en) * | 2008-06-26 | 2008-07-30 | Hemosol Biopharma Inc | Composition |
PT2318029T (pt) | 2008-07-23 | 2018-01-10 | Ambrx Inc | Polipéptidos de g-csf bovino modificados e suas utilizações |
CN103816870B (zh) | 2008-12-03 | 2016-11-23 | 株式会社钟化 | 含有甲酰基的多孔性载体、使用该多孔性载体的吸附体以及它们的制造方法 |
CA2755586C (en) * | 2009-03-20 | 2015-06-23 | Fpinnovations | Cellulose materials with novel properties |
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2005
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- 2005-03-11 CN CNA200580012503XA patent/CN1946742A/zh active Pending
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- 2005-03-11 DE DE202005021885U patent/DE202005021885U1/de not_active Expired - Lifetime
- 2005-03-11 EP EP05716005A patent/EP1725589A1/en not_active Ceased
- 2005-03-11 EA EA200601672A patent/EA010501B1/ru not_active IP Right Cessation
- 2005-03-11 BR BRPI0508607-8A patent/BRPI0508607A/pt not_active IP Right Cessation
- 2005-03-11 KR KR1020067020903A patent/KR101186821B1/ko not_active IP Right Cessation
- 2005-03-11 CN CN200910165389A patent/CN101659704A/zh active Pending
- 2005-03-11 WO PCT/EP2005/002653 patent/WO2005092928A1/en active Application Filing
- 2005-03-11 SG SG200901716-1A patent/SG151261A1/en unknown
- 2005-03-11 JP JP2007502307A patent/JP5191729B2/ja not_active Expired - Fee Related
- 2005-03-11 EP EP10011719A patent/EP2336192A1/en not_active Withdrawn
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Also Published As
Publication number | Publication date |
---|---|
CN101659704A (zh) | 2010-03-03 |
CN1946742A (zh) | 2007-04-11 |
TWI417303B (zh) | 2013-12-01 |
BRPI0508607A (pt) | 2007-07-31 |
EA200601672A1 (ru) | 2007-04-27 |
EA010501B1 (ru) | 2008-10-30 |
ZA200607251B (en) | 2009-03-25 |
CA2558738A1 (en) | 2005-10-06 |
EP1725589A1 (en) | 2006-11-29 |
AU2005225513A1 (en) | 2005-10-06 |
US8287850B2 (en) | 2012-10-16 |
EP2336192A1 (en) | 2011-06-22 |
IL177730A0 (en) | 2006-12-31 |
SG151261A1 (en) | 2009-04-30 |
KR20070012400A (ko) | 2007-01-25 |
AU2005225513B2 (en) | 2012-01-12 |
TW200600519A (en) | 2006-01-01 |
US20070134197A1 (en) | 2007-06-14 |
IL177730A (en) | 2013-11-28 |
WO2005092928A1 (en) | 2005-10-06 |
JP2007527892A (ja) | 2007-10-04 |
CA2558738C (en) | 2013-02-05 |
AR048035A1 (es) | 2006-03-22 |
DE202005021885U1 (de) | 2011-03-03 |
JP5191729B2 (ja) | 2013-05-08 |
KR101186821B1 (ko) | 2012-09-28 |
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