NO20053179L - Aldonsyreestere, fremgangsmater for fremstilling derav og fremgangsmater for fremstilling av farmasoytisk aktive ingredienser som er bundet til polysakkarider eller polysakkarid-derivater pa frie aminogrupper. - Google Patents

Aldonsyreestere, fremgangsmater for fremstilling derav og fremgangsmater for fremstilling av farmasoytisk aktive ingredienser som er bundet til polysakkarider eller polysakkarid-derivater pa frie aminogrupper.

Info

Publication number
NO20053179L
NO20053179L NO20053179A NO20053179A NO20053179L NO 20053179 L NO20053179 L NO 20053179L NO 20053179 A NO20053179 A NO 20053179A NO 20053179 A NO20053179 A NO 20053179A NO 20053179 L NO20053179 L NO 20053179L
Authority
NO
Norway
Prior art keywords
processes
acid esters
active ingredients
pharmaceutically active
aldonic acid
Prior art date
Application number
NO20053179A
Other languages
English (en)
Other versions
NO20053179D0 (no
Inventor
Klaus Sommermeyer
Original Assignee
Supramol Parenteral Colloids
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Supramol Parenteral Colloids filed Critical Supramol Parenteral Colloids
Publication of NO20053179D0 publication Critical patent/NO20053179D0/no
Publication of NO20053179L publication Critical patent/NO20053179L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/02—Esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/16—Ether-esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/18—Oxidised starch
    • C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B33/00—Preparation of derivatives of amylose
    • C08B33/02—Esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B35/00—Preparation of derivatives of amylopectin
    • C08B35/02—Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Det beskrives aldonsyreestere av stivelsesfraksjoner eller stivelsesfraksjonsderivat som selektivt er oksidert ved den reduserende kjedeende ved dannelse av aldonsyrer. Det beskrives videre faststoffer og oppløsninger inneholdende disse aldonsyreestre. Videre beskrives det fremgangsmåter for fremstilling av disse aldonsyreestre, fremgangsmåter for fremstilling av farmasøytisk aktive bestanddeler koblet til polysakkarider eller polysakkaridderivater på frie aminofunksjoner og det beskrives videre farmasøytisk aktive bestanddeler som oppnås på denne måte.
NO20053179A 2002-12-04 2005-06-28 Aldonsyreestere, fremgangsmater for fremstilling derav og fremgangsmater for fremstilling av farmasoytisk aktive ingredienser som er bundet til polysakkarider eller polysakkarid-derivater pa frie aminogrupper. NO20053179L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10256558A DE10256558A1 (de) 2002-12-04 2002-12-04 Ester von Polysaccharid Aldonsäuren, Verfahren zu ihrer Herstellung und Verwendung zur Kopplung an pharmazeutische Wirkstoffe
PCT/EP2003/013622 WO2004050710A2 (de) 2002-12-04 2003-12-03 Aldonsäure-ester, verfahren zu ihrer herstellung und verfahren zur herstellung von mit polysacchariden oder polysaccharid-derivaten an freien aminogruppen gekoppelten pharmazeutischen wirkstoffen

Publications (2)

Publication Number Publication Date
NO20053179D0 NO20053179D0 (no) 2005-06-28
NO20053179L true NO20053179L (no) 2005-08-15

Family

ID=32403695

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053179A NO20053179L (no) 2002-12-04 2005-06-28 Aldonsyreestere, fremgangsmater for fremstilling derav og fremgangsmater for fremstilling av farmasoytisk aktive ingredienser som er bundet til polysakkarider eller polysakkarid-derivater pa frie aminogrupper.

Country Status (15)

Country Link
US (1) US20060052342A1 (no)
EP (1) EP1567558A2 (no)
JP (1) JP4749720B2 (no)
KR (1) KR101170033B1 (no)
CN (1) CN100535015C (no)
AU (1) AU2003288218B2 (no)
BR (1) BR0316493A (no)
CA (1) CA2504799A1 (no)
DE (1) DE10256558A1 (no)
MX (1) MXPA05005572A (no)
NO (1) NO20053179L (no)
PL (1) PL210453B1 (no)
RU (1) RU2330046C2 (no)
WO (1) WO2004050710A2 (no)
ZA (1) ZA200503135B (no)

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DE10112825A1 (de) 2001-03-16 2002-10-02 Fresenius Kabi De Gmbh HESylierung von Wirkstoffen in wässriger Lösung
DE10209822A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
DE10209821A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung von Proteinen an ein modifiziertes Polysaccharid
CA2495242A1 (en) 2002-09-11 2004-03-25 Fresenius Kabi Deutschland Gmbh Hasylated polypeptides, especially hasylated erythropoietin
AU2003273413A1 (en) 2002-10-08 2004-05-04 Fresenius Kabi Deutschland Gmbh Pharmaceutically active oligosaccharide conjugates
WO2005014655A2 (en) 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
AU2005210142A1 (en) * 2004-02-09 2005-08-18 Noxxon Pharma Ag Method for producing conjugates of polysaccharides and polynucleotides
DE102004009783A1 (de) * 2004-02-28 2005-09-15 Supramol Parenteral Colloids Gmbh Hyperverzweigte Stärkefraktion, Verfahren zu ihrer Herstellung und ihre Konjugate mit pharmazeutischen Wirkstoffen
WO2005092928A1 (en) 2004-03-11 2005-10-06 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination
EP2070950A1 (en) 2007-12-14 2009-06-17 Fresenius Kabi Deutschland GmbH Hydroxyalkyl starch derivatives and process for their preparation
EP2070951A1 (en) * 2007-12-14 2009-06-17 Fresenius Kabi Deutschland GmbH Method for producing a hydroxyalkyl starch derivatives with two linkers
US9296810B2 (en) 2008-05-02 2016-03-29 Novartis Ag Fibronectin-based binding molecules and uses thereof
WO2011051327A2 (en) 2009-10-30 2011-05-05 Novartis Ag Small antibody-like single chain proteins
WO2011051466A1 (en) 2009-11-02 2011-05-05 Novartis Ag Anti-idiotypic fibronectin-based binding molecules and uses thereof
WO2011092233A1 (en) 2010-01-29 2011-08-04 Novartis Ag Yeast mating to produce high-affinity combinations of fibronectin-based binders
WO2013113503A1 (en) 2012-01-31 2013-08-08 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and an oligonucleotide

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US2868781A (en) * 1956-04-23 1959-01-13 Monsanto Chemicals Carbohydrate esters of carboxylic acids and methods of preparing same
US4125492A (en) 1974-05-31 1978-11-14 Pedro Cuatrecasas Affinity chromatography of vibrio cholerae enterotoxin-ganglioside polysaccharide and the biological effects of ganglioside-containing soluble polymers
EP0019403B1 (en) * 1979-05-10 1985-07-31 American Hospital Supply Corporation Hydroxyalkyl-starch drug carrier
DE3029307A1 (de) * 1980-08-01 1982-03-04 Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG, 6380 Bad Homburg Haemoglobin enthaltendes blutersatzmittel
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DE10302520A1 (de) * 2003-01-23 2004-08-05 Supramol Parenteral Colloids Gmbh Kohlensäurediester von Stärkefraktionen und deren Derivate, Verfahren zu ihrer Herstellung und Verwendung zur Kopplung an pharmazeutische Wirkstoffe
WO2005014655A2 (en) * 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
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DE102004009783A1 (de) * 2004-02-28 2005-09-15 Supramol Parenteral Colloids Gmbh Hyperverzweigte Stärkefraktion, Verfahren zu ihrer Herstellung und ihre Konjugate mit pharmazeutischen Wirkstoffen
EP1758608A2 (en) * 2004-03-11 2007-03-07 Fresenius Kabi Deutschland GmbH Conjugates of hydroxyethyl starch and erythropoietin

Also Published As

Publication number Publication date
MXPA05005572A (es) 2005-11-23
KR101170033B1 (ko) 2012-08-01
ZA200503135B (en) 2006-07-26
CN100535015C (zh) 2009-09-02
PL375693A1 (en) 2005-12-12
EP1567558A2 (de) 2005-08-31
CA2504799A1 (en) 2004-06-17
NO20053179D0 (no) 2005-06-28
DE10256558A1 (de) 2004-09-16
PL210453B1 (pl) 2012-01-31
RU2005120736A (ru) 2006-01-20
US20060052342A1 (en) 2006-03-09
RU2330046C2 (ru) 2008-07-27
CN1720264A (zh) 2006-01-11
AU2003288218B2 (en) 2010-05-20
JP4749720B2 (ja) 2011-08-17
AU2003288218A1 (en) 2004-06-23
KR20050072832A (ko) 2005-07-12
BR0316493A (pt) 2005-10-11
WO2004050710A3 (de) 2004-09-02
JP2006509849A (ja) 2006-03-23
WO2004050710A2 (de) 2004-06-17

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