DK110188D0 - High molecular weight prodrug derivatives of antiinflammatory drugs - Google Patents

High molecular weight prodrug derivatives of antiinflammatory drugs

Info

Publication number
DK110188D0
DK110188D0 DK110188A DK110188A DK110188D0 DK 110188 D0 DK110188 D0 DK 110188D0 DK 110188 A DK110188 A DK 110188A DK 110188 A DK110188 A DK 110188A DK 110188 D0 DK110188 D0 DK 110188D0
Authority
DK
Denmark
Prior art keywords
absent
residue
formula
group
drug
Prior art date
Application number
DK110188A
Other languages
English (en)
Inventor
Claus Selch Larsen
Marianne Johansen
Elin Harboe
Peter Kurtzhals
Henning Peter Olesen
Original Assignee
Claus Selch Larsen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Claus Selch Larsen filed Critical Claus Selch Larsen
Priority to DK110188A priority Critical patent/DK110188D0/da
Publication of DK110188D0 publication Critical patent/DK110188D0/da
Priority to PCT/DK1989/000047 priority patent/WO1989008119A1/en
Priority to AT89302051T priority patent/ATE83383T1/de
Priority to DE8989302051T priority patent/DE68903852T2/de
Priority to JP1503409A priority patent/JPH04505334A/ja
Priority to EP19890302051 priority patent/EP0331471B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
DK110188A 1988-03-02 1988-03-02 High molecular weight prodrug derivatives of antiinflammatory drugs DK110188D0 (da)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DK110188A DK110188D0 (da) 1988-03-02 1988-03-02 High molecular weight prodrug derivatives of antiinflammatory drugs
PCT/DK1989/000047 WO1989008119A1 (en) 1988-03-02 1989-03-01 High molecular weight prodrug derivatives of anti-inflammatory drugs
AT89302051T ATE83383T1 (de) 1988-03-02 1989-03-01 Hochmolekulare prodrogenderivate von entzuendungshemmenden arzneimitteln.
DE8989302051T DE68903852T2 (de) 1988-03-02 1989-03-01 Hochmolekulare prodrogenderivate von entzuendungshemmenden arzneimitteln.
JP1503409A JPH04505334A (ja) 1988-03-02 1989-03-01 抗炎症薬の高分子量プロドラッグ誘導体
EP19890302051 EP0331471B1 (en) 1988-03-02 1989-03-01 High molecular weight prodrug derivatives of antiinflammatory drugs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK110188A DK110188D0 (da) 1988-03-02 1988-03-02 High molecular weight prodrug derivatives of antiinflammatory drugs

Publications (1)

Publication Number Publication Date
DK110188D0 true DK110188D0 (da) 1988-03-02

Family

ID=8101004

Family Applications (1)

Application Number Title Priority Date Filing Date
DK110188A DK110188D0 (da) 1988-03-02 1988-03-02 High molecular weight prodrug derivatives of antiinflammatory drugs

Country Status (6)

Country Link
EP (1) EP0331471B1 (da)
JP (1) JPH04505334A (da)
AT (1) ATE83383T1 (da)
DE (1) DE68903852T2 (da)
DK (1) DK110188D0 (da)
WO (1) WO1989008119A1 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL98087A (en) * 1990-05-04 1996-11-14 Perio Prod Ltd Preparation for dispensing drugs in the colon
RU2113221C1 (ru) * 1990-05-04 1998-06-20 Ииссум Рисерч Дивелопмент Компани оф дзе Хебрю Юниверсити оф Иеруcалим Фармацевтическая форма для введения лекарственного средства в ободочную кишку, способ введения лекарственного препарата и способ получения матриц для такой формы
AU650689B2 (en) * 1990-11-06 1994-06-30 Fgn, Inc. Esters and amides of substituted indenyl acetic acids
AU659107B2 (en) * 1990-11-06 1995-05-11 Fgn, Inc. Method for treating colonic polyps by the use of esters and amides of substituted fused ring phenyl acetic acids
AU650914B2 (en) * 1990-11-06 1994-07-07 Fgn, Inc. Esters and amides of substituted phenyl acetic acids
AU658373B2 (en) * 1990-11-06 1995-04-13 Fgn, Inc. Esters and amides of substituted pyrrole acetic acids
AU659106B2 (en) * 1990-11-06 1995-05-11 Fgn, Inc. Method for treating colonic polyps by the use of esters and amides of substituted phenyl and pyridyl amino carboxylates
EP0540751A4 (en) * 1991-05-20 1994-10-26 Eisai Co Ltd Steroid compound combined with polysaccharide
SE9103110D0 (sv) * 1991-10-24 1991-10-24 Kabi Pharmacia Ab New drug formulation
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
ES2241063T3 (es) * 1996-12-13 2005-10-16 Lescarden, Inc. Tratamiento de la osteoartritis mediante la administracion de poli-n-acetil-d-glucosamina.
US5902800A (en) * 1998-03-27 1999-05-11 Glenpharma Dextran formulations and method for treatment of inflammatory joint disorders
FR2809735B1 (fr) * 2000-06-02 2003-08-01 Biodex Composition pharmaceutique contenant au moins un polymere associe ou conjugue a au moins un sel d'un acide phenylalkycarboxylique, polymeres conjugues et leurs applications
DE10112825A1 (de) 2001-03-16 2002-10-02 Fresenius Kabi De Gmbh HESylierung von Wirkstoffen in wässriger Lösung
US6897348B2 (en) 2001-12-19 2005-05-24 Kimberly Clark Worldwide, Inc Bandage, methods of producing and using same
DE10209821A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung von Proteinen an ein modifiziertes Polysaccharid
DE10209822A1 (de) * 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
CA2496317C (en) 2002-09-11 2014-02-18 Fresenius Kabi Deutschland Gmbh Method of producing hydroxyalkyl starch derivatives
AU2003273413A1 (en) 2002-10-08 2004-05-04 Fresenius Kabi Deutschland Gmbh Pharmaceutically active oligosaccharide conjugates
WO2005014655A2 (en) 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
EP1710257A4 (en) * 2004-01-07 2011-03-23 Seikagaku Kogyo Co Ltd HYALURONIC ACID DERIVATIVE AND MEDICAMENT CONTAINING THEREOF
SG151261A1 (en) 2004-03-11 2009-04-30 Fresenius Kabi De Gmbh Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination
EP3269394A1 (en) * 2004-03-31 2018-01-17 University of Utah Research Foundation Macromolecular delivery systems for non-invasive imaging, evaluation and treatment of arthritis and other inflammatory diseases
EP2070950A1 (en) 2007-12-14 2009-06-17 Fresenius Kabi Deutschland GmbH Hydroxyalkyl starch derivatives and process for their preparation
WO2019178443A1 (en) * 2018-03-16 2019-09-19 University Of Massachusetts Yeast cell wall particle encapsulation of biodegradable pro-payloads
CN112154158A (zh) * 2018-03-22 2020-12-29 持田制药株式会社 连接有非甾体抗炎化合物的海藻酸衍生物
WO2021060395A1 (ja) * 2019-09-25 2021-04-01 持田製薬株式会社 徐放性医薬組成物
WO2021060351A1 (ja) * 2019-09-25 2021-04-01 持田製薬株式会社 ＮＳＡＩＤｓ結合アルギン酸誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003990A (en) * 1972-06-29 1977-01-18 Societe Anonyme Dite: L'oreal Anti-inflammatory polymers, pharmaceutical compositions containing the same and process for producing said polymers
SE431937B (sv) * 1979-01-29 1984-03-12 Perstorp Ab Salicylazosulfapyridinhaltigt medicinskt preparat
EP0019403B1 (en) * 1979-05-10 1985-07-31 American Hospital Supply Corporation Hydroxyalkyl-starch drug carrier
GB8328917D0 (en) * 1983-10-28 1983-11-30 Fisons Plc Blood substitute
IT1203814B (it) * 1986-06-30 1989-02-23 Fidia Farmaceutici Esteri dell'acido alginico

Also Published As

Publication number Publication date
JPH04505334A (ja) 1992-09-17
DE68903852D1 (de) 1993-01-28
EP0331471A1 (en) 1989-09-06
ATE83383T1 (de) 1993-01-15
DE68903852T2 (de) 1993-06-17
WO1989008119A1 (en) 1989-09-08
EP0331471B1 (en) 1992-12-16

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