DK2013166T3 - N-carbamoylmethyl-4(R)-phenyl-2-pyrrolidon, fremgangsmåde til fremstilling heraf og farmaceutisk anvendelse - Google Patents
N-carbamoylmethyl-4(R)-phenyl-2-pyrrolidon, fremgangsmåde til fremstilling heraf og farmaceutisk anvendelseInfo
- Publication number
- DK2013166T3 DK2013166T3 DK07726915.7T DK07726915T DK2013166T3 DK 2013166 T3 DK2013166 T3 DK 2013166T3 DK 07726915 T DK07726915 T DK 07726915T DK 2013166 T3 DK2013166 T3 DK 2013166T3
- Authority
- DK
- Denmark
- Prior art keywords
- phenyl
- carbamoylmethyl
- preparation
- pyrrolidone
- pharmaceutical use
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LVP-06-45A LV13630B (en) | 2006-03-16 | 2006-03-16 | Method of preparation and use of pharmaceutically active n-carbamoylmethyl-4(r)-phenyl-2-pyrrolidinone |
PCT/EP2007/052424 WO2007104780A2 (en) | 2006-03-16 | 2007-03-15 | N- carbamoylmethyl- 4- (r) -phenyl-2-pyrr0lidin0ne, method of its preparation and pharmaceutical use |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2013166T3 true DK2013166T3 (da) | 2010-07-05 |
Family
ID=38461010
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07726915.7T DK2013166T3 (da) | 2006-03-16 | 2007-03-15 | N-carbamoylmethyl-4(R)-phenyl-2-pyrrolidon, fremgangsmåde til fremstilling heraf og farmaceutisk anvendelse |
Country Status (21)
Country | Link |
---|---|
US (2) | US9102615B2 (da) |
EP (1) | EP2013166B1 (da) |
CN (1) | CN101448786A (da) |
AT (1) | ATE460396T1 (da) |
CA (1) | CA2647206C (da) |
CY (1) | CY1110170T1 (da) |
DE (1) | DE602007005244D1 (da) |
DK (1) | DK2013166T3 (da) |
EA (1) | EA014668B1 (da) |
EE (1) | EE05536B1 (da) |
ES (1) | ES2342024T3 (da) |
GE (1) | GEP20104915B (da) |
HR (1) | HRP20090524C1 (da) |
LT (1) | LT5589B (da) |
LV (1) | LV13630B (da) |
ME (1) | ME01192B (da) |
PL (1) | PL2013166T3 (da) |
PT (1) | PT2013166E (da) |
SI (1) | SI2013166T1 (da) |
UA (1) | UA96440C2 (da) |
WO (1) | WO2007104780A2 (da) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LV14346B (lv) * | 2009-11-05 | 2011-07-20 | Grindeks, A/S | 2-(4-Fenil-5-metil-2-oksopirolidin-1-il)-acetamīda 4R,5S-enantiomērs ar nootropo aktivitāti |
RU2013141257A (ru) * | 2011-03-11 | 2015-04-20 | Гриндекс | 4r, 5r-энантиомер 2-(5-метил-2-оксо-4-фенилпирролидин-1-ил) ацетамида с ноотропной активностью |
RU2480214C1 (ru) | 2011-09-22 | 2013-04-27 | Валентина Ивановна Ахапкина | Состав, обладающий модуляторной активностью с соразмерным влиянием, фармацевтическая субстанция (варианты), применение фармацевтической субстанции, фармацевтическая и парафармацевтическая композиция (варианты), способ получения фармацевтических составов |
DK3517541T3 (da) | 2012-05-08 | 2020-09-07 | Nicox Ophthalmics Inc | Polymorf form af fluticasonpropionat |
TW201408294A (zh) | 2012-07-05 | 2014-03-01 | Merz Pharma Gmbh & Co Kgaa | (r)-苯基披喇瑟盪於治療帕金森氏症之用除 |
TW201408293A (zh) | 2012-07-05 | 2014-03-01 | Merz Pharma Gmbh & Co Kgaa | (r)-苯基披喇瑟盪於治療疾病相關疲勞之用途 |
LV15003B (lv) * | 2013-10-22 | 2015-08-20 | Latvijas Organiskās Sintēzes Institūts | Farmaceitiska kompozīcija ķermeņa masas pieauguma kontrolei |
LV15015B (lv) | 2013-12-13 | 2015-12-20 | Olainfarm, A/S | 3-karboksi-4-(R)-fenilpirolidin-2-ona sāls un tā pielietošana |
LV15016B (lv) * | 2013-12-18 | 2016-01-20 | Olainfarm, A/S | N-karbamoilmetil-4(R)-fenil-2-pirolidinona polimorfās formas |
EP2891491A1 (en) | 2014-01-03 | 2015-07-08 | Merz Pharma GmbH & Co. KGaA | Use of (r)-phenylpiracetam for the treatment of sleep disorders |
LV15072B (lv) | 2014-05-14 | 2016-09-20 | Olainfarm, A/S | Farmaceitiska kompozīcija izmantošanai patoloģiska stāvokļa, kam raksturīga paaugstināta iNOS gēna ekspresija, profilaksei un ārstēšanai |
EP3127539A1 (en) * | 2015-08-03 | 2017-02-08 | Latvian Institute Of Organic Synthesis | Use of 2-(5s-methyl-2-oxo-4r-phenyl-pyrrolidin-1-yl)-acetamide in the treatment of seizures |
WO2024049236A1 (ko) * | 2022-08-31 | 2024-03-07 | 고려대학교 산학협력단 | 키랄 감마 락탐 유도체 또는 이의 약학적으로 허용가능한 염 및 이의 제조방법 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0004297D0 (en) * | 2000-02-23 | 2000-04-12 | Ucb Sa | 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses |
RU2232578C1 (ru) * | 2003-04-10 | 2004-07-20 | Ахапкина Валентина Ивановна | Вещество, обладающее антидепрессивной активностью |
RU2289404C1 (ru) * | 2005-04-06 | 2006-12-20 | ГОУ ВПО "Московский государственный медико-стоматологический университет Министерства здравоохранения РФ" | Способ премедикации у пациентов со средним уровнем психоэмоционального напряжения при амбулаторных стоматологических вмешательствах |
-
2006
- 2006-03-16 LV LVP-06-45A patent/LV13630B/en unknown
-
2007
- 2007-03-15 SI SI200730253T patent/SI2013166T1/sl unknown
- 2007-03-15 AT AT07726915T patent/ATE460396T1/de active
- 2007-03-15 PL PL07726915T patent/PL2013166T3/pl unknown
- 2007-03-15 DK DK07726915.7T patent/DK2013166T3/da active
- 2007-03-15 EE EEP200800063A patent/EE05536B1/xx not_active IP Right Cessation
- 2007-03-15 EA EA200801978A patent/EA014668B1/ru not_active IP Right Cessation
- 2007-03-15 ME MEP-2009-293A patent/ME01192B/me unknown
- 2007-03-15 EP EP07726915A patent/EP2013166B1/en active Active
- 2007-03-15 PT PT07726915T patent/PT2013166E/pt unknown
- 2007-03-15 CN CNA2007800177832A patent/CN101448786A/zh active Pending
- 2007-03-15 US US12/226,332 patent/US9102615B2/en not_active Expired - Fee Related
- 2007-03-15 ES ES07726915T patent/ES2342024T3/es active Active
- 2007-03-15 DE DE602007005244T patent/DE602007005244D1/de active Active
- 2007-03-15 UA UAA200812099A patent/UA96440C2/ru unknown
- 2007-03-15 CA CA2647206A patent/CA2647206C/en not_active Expired - Fee Related
- 2007-03-15 GE GEAP200710934A patent/GEP20104915B/en unknown
- 2007-03-15 WO PCT/EP2007/052424 patent/WO2007104780A2/en active Application Filing
-
2008
- 2008-09-22 LT LT2008075A patent/LT5589B/lt not_active IP Right Cessation
-
2009
- 2009-09-30 HR HRP20090524AA patent/HRP20090524C1/hr not_active IP Right Cessation
-
2010
- 2010-06-08 CY CY20101100506T patent/CY1110170T1/el unknown
-
2015
- 2015-04-16 US US14/688,633 patent/US9382203B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2007104780A2 (en) | 2007-09-20 |
CA2647206A1 (en) | 2007-09-20 |
US20100022784A1 (en) | 2010-01-28 |
ES2342024T3 (es) | 2010-06-30 |
ATE460396T1 (de) | 2010-03-15 |
HRP20090524A2 (hr) | 2009-12-31 |
ME01192B (me) | 2012-12-20 |
DE602007005244D1 (de) | 2010-04-22 |
GEP20104915B (en) | 2010-03-10 |
PT2013166E (pt) | 2010-06-09 |
LT5589B (lt) | 2009-08-25 |
EA200801978A1 (ru) | 2009-04-28 |
CA2647206C (en) | 2011-09-27 |
LV13630B (en) | 2007-12-20 |
CN101448786A (zh) | 2009-06-03 |
WO2007104780A3 (en) | 2007-11-29 |
PL2013166T3 (pl) | 2010-08-31 |
EP2013166B1 (en) | 2010-03-10 |
EE05536B1 (et) | 2012-04-16 |
EP2013166A2 (en) | 2009-01-14 |
US9382203B2 (en) | 2016-07-05 |
CY1110170T1 (el) | 2015-01-14 |
SI2013166T1 (sl) | 2010-07-30 |
LT2008075A (en) | 2009-06-25 |
UA96440C2 (ru) | 2011-11-10 |
US20150216846A1 (en) | 2015-08-06 |
EA014668B1 (ru) | 2010-12-30 |
US9102615B2 (en) | 2015-08-11 |
HRPK20090524B3 (hr) | 2012-12-31 |
EE200800063A (et) | 2008-12-15 |
HRP20090524C1 (hr) | 2017-03-10 |
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