NO20041531L - Alkyleterderivater eller salter derav - Google Patents
Alkyleterderivater eller salter deravInfo
- Publication number
- NO20041531L NO20041531L NO20041531A NO20041531A NO20041531L NO 20041531 L NO20041531 L NO 20041531L NO 20041531 A NO20041531 A NO 20041531A NO 20041531 A NO20041531 A NO 20041531A NO 20041531 L NO20041531 L NO 20041531L
- Authority
- NO
- Norway
- Prior art keywords
- group
- activity
- membered
- integer
- alkyl ether
- Prior art date
Links
- 150000005215 alkyl ethers Chemical class 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 230000000694 effects Effects 0.000 abstract 3
- 125000003277 amino group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 210000005036 nerve Anatomy 0.000 abstract 1
- 210000002241 neurite Anatomy 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 210000000578 peripheral nerve Anatomy 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Indole Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Alkyleter-derivat representert ved den generelle formel:. hvor hver av Rog Rrepresenterer én eller flere grupper valgt fra et hydrogenatom, et halogenatom, en alkylgruppe, en arylgnippe, en aralkylgruppe, en alkoksygruppe, en aryloksygruppe, en alkyltiogruppe, en aryltiogruppe, en alkenylgruppe, en alkenyloksygruppe, en aminogruppe, en alkylsulfonylgruppe, en arylsulfonylgruppe, en karbamoylgnippe, en heterocyklisk gruppe, en hydroksylgruppe, en karboksylgruppe, en nitrogruppe, en oksogruppe og lignende; Rer en alkylaminogruppe, en aminogruppe, en hydroksylgruppe eller lignende; ring A er en 5-leddet eller 6-leddet.heteroaromatisk ring eller en benzenring; hver av m og n er et helt tall på 1 til 6; og p er et helt tall på 1 til 3 eller det salt har aktivitet for å beskytte neuroner, aktivitet for å akselerere nerveregenerering og aktivitet for å akselerere neuritutvidelse og er således anvendelig som et terapeutisk middel for sykdommner i sentrale og perifere nerver.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001321381 | 2001-10-19 | ||
| PCT/JP2002/010827 WO2003035647A1 (fr) | 2001-10-19 | 2002-10-18 | Derives ou sels d'ether d'alkyle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20041531L true NO20041531L (no) | 2004-04-15 |
| NO325780B1 NO325780B1 (no) | 2008-07-14 |
Family
ID=19138603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20041531A NO325780B1 (no) | 2001-10-19 | 2004-04-15 | Alkyleter-derivater eller deres salter, fremgangsmater for fremstilling av slike samt farmasoytiske preparater inneholdende slike |
Country Status (23)
| Country | Link |
|---|---|
| US (4) | USRE43676E1 (no) |
| EP (1) | EP1437353B1 (no) |
| JP (1) | JP4398247B2 (no) |
| KR (1) | KR100956990B1 (no) |
| CN (2) | CN101643470B (no) |
| AT (1) | ATE364604T1 (no) |
| AU (1) | AU2002344107B2 (no) |
| BR (1) | BRPI0213393B8 (no) |
| CA (1) | CA2464358C (no) |
| CY (1) | CY1106714T1 (no) |
| DE (1) | DE60220694T2 (no) |
| DK (1) | DK1437353T3 (no) |
| ES (1) | ES2287324T3 (no) |
| HU (1) | HU230407B1 (no) |
| IL (2) | IL161308A0 (no) |
| MX (1) | MXPA04003541A (no) |
| NO (1) | NO325780B1 (no) |
| NZ (1) | NZ532328A (no) |
| PL (2) | PL217872B1 (no) |
| PT (1) | PT1437353E (no) |
| RO (1) | RO122203B1 (no) |
| WO (1) | WO2003035647A1 (no) |
| ZA (1) | ZA200402806B (no) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002344107B2 (en) * | 2001-10-19 | 2007-11-01 | Toyama Chemical Co., Ltd. | Alkyl ether derivatives or salts thereof |
| IL165589A (en) | 2002-06-14 | 2012-04-30 | Toyama Chemical Co Ltd | Pharmaceutical preparation to improve brain function and use |
| EP1614419B1 (en) * | 2003-04-17 | 2012-08-08 | Toyama Chemical Co., Ltd. | Preventive/remedy for retinal nerve diseases containing alkyl ether derivatives or salts thereof |
| AU2011204959B2 (en) * | 2005-03-28 | 2012-04-12 | Toyama Chemical Co., Ltd. | Process for production of 1-(3-(2-(1-benzothiophen-5-YL)- ethoxy)propyl)azetidin-3-ol or salts thereof |
| ATE546443T1 (de) | 2005-03-28 | 2012-03-15 | Toyama Chemical Co Ltd | Prozess zur herstellung von 1-(3-(2-(1- benzothiophen-5-yl)-ethoxy)propionsäure sowie deren salze |
| JP4902247B2 (ja) * | 2005-04-08 | 2012-03-21 | 富山化学工業株式会社 | ２−（１−ベンゾチオフェン−５−イル）エタノールの新規製造法およびその中間体 |
| JP2006328058A (ja) * | 2005-04-27 | 2006-12-07 | Toyama Chem Co Ltd | ２−（１−ベンゾチオフェン−５−イル）エタノールの新規製造法およびその中間体 |
| US8119625B2 (en) | 2006-04-26 | 2012-02-21 | Toyama Chemical Co., Ltd. | Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof |
| SI2011796T1 (sl) * | 2006-04-26 | 2015-02-27 | Toyama Chemical Co., Ltd. | Induktor nevrogeneze ali terapevtska uäśinkovina proti nevropatiji, vsebujoäśa derivat alkilnega etra ali sol le-tega |
| CA2659835A1 (en) * | 2006-08-04 | 2008-02-07 | Toyama Chemical Co., Ltd. | Protein kinase c activity enhancer containing alkyl ether derivative or salt thereof |
| US8026232B2 (en) | 2008-05-28 | 2011-09-27 | Toyama Chemical Co., Ltd. | Benzothiophene oxide derivative and salt thereof |
| TR201907882T4 (tr) | 2012-02-22 | 2019-06-21 | Fujifilm Toyama Chemical Co Ltd | 1-(3-(2-(1-Benzotiofen-5-il)etoksi)propil)azetidin-3-olü veya onun tuzunu içeren katı farmasötik bileşim |
| LT3100725T (lt) | 2014-01-31 | 2020-08-10 | Fujifilm Toyama Chemical Co., Ltd. | Reabilitacijos poveikį po nervo pažeidimo sustiprinanti priemonė, apimanti alkileterio darinį arba jo druską |
| WO2016199878A1 (ja) * | 2015-06-11 | 2016-12-15 | 富山化学工業株式会社 | シグマ受容体結合剤 |
| JP6860502B2 (ja) | 2015-12-25 | 2021-04-14 | 富士フイルム富山化学株式会社 | １−（３−（２−（１−ベンゾチオフェン−５−イル）エトキシ）プロピル）アゼチジン−３−オールまたはその塩を含む錠剤 |
| CN110139641B (zh) * | 2016-12-28 | 2022-09-09 | 富士胶片富山化学株式会社 | 外用组合物 |
| JP7079209B2 (ja) | 2016-12-28 | 2022-06-01 | 富士フイルム富山化学株式会社 | 医薬組成物およびその製造方法 |
| JP7057287B2 (ja) | 2016-12-28 | 2022-04-19 | 富士フイルム富山化学株式会社 | 医薬組成物 |
| US10849880B2 (en) | 2016-12-28 | 2020-12-01 | Fujifilm Toyama Chemical Co., Ltd. | Pharmaceutical composition |
| AU2018277981B2 (en) | 2017-06-02 | 2021-04-08 | Fujifilm Toyama Chemical Co., Ltd. | Agent for preventing or treating spinocerebellar ataxia |
| WO2018221728A1 (ja) | 2017-06-02 | 2018-12-06 | 富山化学工業株式会社 | アルツハイマー型認知症予防または治療剤 |
| US11666551B2 (en) | 2017-06-02 | 2023-06-06 | Fujifilm Toyama Chemical Co., Ltd. | Agent for reducing amount of amyloid β protein |
| CA3067456C (en) | 2017-06-02 | 2023-03-14 | Fujifilm Toyama Chemical Co., Ltd. | Agent for preventing or treating tauopathy |
| NZ759585A (en) | 2017-06-02 | 2022-02-25 | Fujifilm Toyama Chemical Co Ltd | Agent for preventing or treating brain atrophy |
| JP7227914B2 (ja) | 2017-10-30 | 2023-02-22 | 富士フイルム富山化学株式会社 | エモパミル結合タンパク質結合剤およびその利用 |
| CN114853619B (zh) * | 2022-05-19 | 2024-05-10 | 神隆医药（常熟）有限公司 | 一种适于工业化生产的n-甲基酪胺盐酸盐的制备方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01156973A (ja) | 1987-09-04 | 1989-06-20 | Tanabe Seiyaku Co Ltd | ベンゾフラン誘導体 |
| JP2887492B2 (ja) | 1990-02-05 | 1999-04-26 | 富山化学工業株式会社 | １，２―エタンジオール誘導体およびその塩 |
| JP3044055B2 (ja) | 1990-08-09 | 2000-05-22 | 富山化学工業株式会社 | １，２―エタンジオール誘導体およびその塩 |
| DK74693D0 (da) | 1993-06-23 | 1993-06-23 | Novo Nordisk As | Novel heterocyclic chemistry |
| JP3232830B2 (ja) | 1993-11-30 | 2001-11-26 | 三菱電機株式会社 | フレキシブルディスク装置のキャリッジ機構 |
| PL187490B1 (pl) | 1994-10-25 | 2004-07-30 | Toyama Chemical Co Ltd | Zastosowanie pochodnej 1,2-etanodiolu lub jej soli do wytwarzania środka wzmacniającego aktywność czynnika wzrostowego nerwu |
| JPH08268883A (ja) | 1994-10-25 | 1996-10-15 | Toyama Chem Co Ltd | １−フェニル−１，２−エタンジオール誘導体またはそ の塩を含有する神経成長因子の作用増強剤 |
| PL185603B1 (pl) | 1995-08-11 | 2003-06-30 | Pfizer | Nowy trihydrat metanosulfonianu (1S,2S)-1-(4-hydroksyfenylo)-2-(4-hydroksy-4-fenylopiperydyn-1-ylo)-1-propanolu i środek farmaceutyczny |
| EP0873990A1 (en) | 1995-09-22 | 1998-10-28 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzoic acid compounds and medicinal use thereof |
| DE19605610A1 (de) | 1996-02-15 | 1997-08-21 | Hoechst Ag | Substituierte Thiophenylalkenylcarbonsäureguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| AU1672597A (en) | 1996-02-20 | 1997-09-10 | Toyama Chemical Co. Ltd. | Cerebral function ameliorant containing 1,2-ethanediol derivatives or salts thereof |
| AU1506499A (en) * | 1997-12-12 | 1999-07-05 | Toyama Chemical Co. Ltd. | Alkyl ether derivatives or salts thereof and calcium antagonists containing the same |
| JP4549452B2 (ja) | 1997-12-12 | 2010-09-22 | 富山化学工業株式会社 | アルキルエーテル誘導体またはその塩並びにそれらを含有するカルシウム拮抗剤 |
| AU770234B2 (en) | 1999-06-11 | 2004-02-19 | Toyama Chemical Co. Ltd. | N-alkoxyalkyl-N, N-dialkylamine derivatives or salts thereof and agents for treating neurodegenerative diseases comprising the same |
| AU2002344107B2 (en) | 2001-10-19 | 2007-11-01 | Toyama Chemical Co., Ltd. | Alkyl ether derivatives or salts thereof |
| IL165589A (en) | 2002-06-14 | 2012-04-30 | Toyama Chemical Co Ltd | Pharmaceutical preparation to improve brain function and use |
| EP1614419B1 (en) | 2003-04-17 | 2012-08-08 | Toyama Chemical Co., Ltd. | Preventive/remedy for retinal nerve diseases containing alkyl ether derivatives or salts thereof |
| ATE546443T1 (de) | 2005-03-28 | 2012-03-15 | Toyama Chemical Co Ltd | Prozess zur herstellung von 1-(3-(2-(1- benzothiophen-5-yl)-ethoxy)propionsäure sowie deren salze |
| US8119625B2 (en) | 2006-04-26 | 2012-02-21 | Toyama Chemical Co., Ltd. | Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof |
| SI2011796T1 (sl) | 2006-04-26 | 2015-02-27 | Toyama Chemical Co., Ltd. | Induktor nevrogeneze ali terapevtska uäśinkovina proti nevropatiji, vsebujoäśa derivat alkilnega etra ali sol le-tega |
| CA2659835A1 (en) | 2006-08-04 | 2008-02-07 | Toyama Chemical Co., Ltd. | Protein kinase c activity enhancer containing alkyl ether derivative or salt thereof |
| US8026232B2 (en) | 2008-05-28 | 2011-09-27 | Toyama Chemical Co., Ltd. | Benzothiophene oxide derivative and salt thereof |
-
2002
- 2002-10-18 AU AU2002344107A patent/AU2002344107B2/en not_active Expired
- 2002-10-18 EP EP02777882A patent/EP1437353B1/en not_active Expired - Lifetime
- 2002-10-18 IL IL16130802A patent/IL161308A0/xx unknown
- 2002-10-18 PL PL402986A patent/PL217872B1/pl unknown
- 2002-10-18 HU HU0500017A patent/HU230407B1/hu unknown
- 2002-10-18 PL PL369601A patent/PL215264B1/pl unknown
- 2002-10-18 RO ROA200400354A patent/RO122203B1/ro unknown
- 2002-10-18 KR KR1020047005687A patent/KR100956990B1/ko active IP Right Grant
- 2002-10-18 DE DE60220694T patent/DE60220694T2/de not_active Expired - Lifetime
- 2002-10-18 NZ NZ532328A patent/NZ532328A/en not_active IP Right Cessation
- 2002-10-18 CN CN2009102038534A patent/CN101643470B/zh not_active Expired - Lifetime
- 2002-10-18 US US13/327,152 patent/USRE43676E1/en not_active Expired - Lifetime
- 2002-10-18 CN CNB028206452A patent/CN100500662C/zh not_active Expired - Lifetime
- 2002-10-18 CA CA2464358A patent/CA2464358C/en not_active Expired - Lifetime
- 2002-10-18 DK DK02777882T patent/DK1437353T3/da active
- 2002-10-18 JP JP2003538163A patent/JP4398247B2/ja not_active Expired - Lifetime
- 2002-10-18 US US10/492,774 patent/US7087594B2/en not_active Ceased
- 2002-10-18 BR BRPI0213393A patent/BRPI0213393B8/pt not_active IP Right Cessation
- 2002-10-18 WO PCT/JP2002/010827 patent/WO2003035647A1/ja active IP Right Grant
- 2002-10-18 MX MXPA04003541A patent/MXPA04003541A/es active IP Right Grant
- 2002-10-18 PT PT02777882T patent/PT1437353E/pt unknown
- 2002-10-18 ES ES02777882T patent/ES2287324T3/es not_active Expired - Lifetime
- 2002-10-18 AT AT02777882T patent/ATE364604T1/de active
-
2004
- 2004-04-07 IL IL161308A patent/IL161308A/en active IP Right Grant
- 2004-04-13 ZA ZA2004/02806A patent/ZA200402806B/en unknown
- 2004-04-15 NO NO20041531A patent/NO325780B1/no not_active IP Right Cessation
-
2006
- 2006-05-03 US US11/416,321 patent/US7468443B2/en not_active Expired - Lifetime
-
2007
- 2007-07-09 CY CY20071100909T patent/CY1106714T1/el unknown
-
2008
- 2008-10-17 US US12/253,379 patent/US8129535B2/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20041531L (no) | Alkyleterderivater eller salter derav | |
| NO20072605L (no) | Nytt antranilinsyrederivat eller et salt derav | |
| CY1117132T1 (el) | Παραγωγο θειαζολιου | |
| DE602004024880D1 (de) | Azetidincarboxamid-derivate zur verwendung zur behandlung von cb1-rezeptor-vermittelten krankheiten | |
| NO20054224L (no) | Nye 2-pyridinkarboksamidderivater | |
| TR200100439T2 (tr) | 1H-İmidazopiridin türevleri | |
| NO20062988L (no) | Sykliske aminderivater med heteroarylring | |
| DE60311821D1 (de) | Dibenzylaminverbindung und deren medizinische verwendung | |
| DE69819891D1 (de) | Spiro chinuclidin-derivate, ihre herstellung und verwendung | |
| TW200716528A (en) | Cyclopropanecarboxamide derivatives | |
| DE60129210D1 (de) | Zyklische amid-derivate | |
| NO20062370L (no) | Amidderivater | |
| HUP0102563A2 (hu) | Indolszármazékok és alkalmazásuk rosszindulatú és egyéb, patológiás sejtproliferáción alapuló megbetegedések kezelésére | |
| MX2009006024A (es) | Derivados de heteroaril piridopirimidona sustituidos. | |
| NO994452L (no) | Substituerte 4-arylmetylen-2-imino-2,3-dihydrotiazoler og derivater, og deres farmasöytiske anvendelse | |
| EP1396493A4 (en) | HETEROCYCLIC COMPOUNDS | |
| WO2001017963A3 (en) | Aminoalkoxy carbazoles and their use as 5-ht ligands | |
| NO992770L (no) | Nye heterocyklisk substituerte benzamider og deres anvendelse ved bekjempelse av sykdommer | |
| CA2336412A1 (en) | Medicament for treatment of diabetes | |
| CA2072785A1 (en) | Pharmacologically active hydrazine derivatives and processes for the preparation thereof | |
| NO20061045L (no) | Imidazolderivater | |
| NO330989B1 (no) | Nye piperazinderivater, fremgangsmater for fremstilling av slike og deres anvendelse som syntesemellomprodukter. | |
| EA200001101A1 (ru) | НОВЫЕ ДИГИДРОФУРО[3,4-b]ХИНОЛИН-1-ОНЫ, СПОСОБ ИХ ПОЛУЧЕНИЯ И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ | |
| NO20012943L (no) | Nye heterocykliske forbindelser og farmasöytiske sammensetninger inneholdende det samme | |
| MY134226A (en) | 1,2-dihydropyrazol-3-ones which control inflammatory cyctokines |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |