PL402986A1 - Pochodna eteru alkilowego lub jej sól, stanowiaca 1-{3-[2-(1-benzotiofen-5-ylo)etoksy]propylo}-3-azetydynol lub jego sól - Google Patents

Pochodna eteru alkilowego lub jej sól, stanowiaca 1-{3-[2-(1-benzotiofen-5-ylo)etoksy]propylo}-3-azetydynol lub jego sól

Info

Publication number
PL402986A1
PL402986A1 PL402986A PL40298602A PL402986A1 PL 402986 A1 PL402986 A1 PL 402986A1 PL 402986 A PL402986 A PL 402986A PL 40298602 A PL40298602 A PL 40298602A PL 402986 A1 PL402986 A1 PL 402986A1
Authority
PL
Poland
Prior art keywords
salt
benzothiophen
ethoxy
propyl
azetydynol
Prior art date
Application number
PL402986A
Other languages
English (en)
Other versions
PL217872B1 (pl
Inventor
Akihito Saitoh
Noboru Iwakami
Tamotsu Takamatsu
Original Assignee
Toyama Chemical Co., Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co., Ltd filed Critical Toyama Chemical Co., Ltd
Publication of PL402986A1 publication Critical patent/PL402986A1/pl
Publication of PL217872B1 publication Critical patent/PL217872B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Przedmiotem wynalazku jest 1-{3-[2-(1-benzotiofen-5-ylo)etoksy]propylo}-3-azetydynol lub jego sól.
PL402986A 2001-10-19 2002-10-18 Pochodna eteru alkilowego lub jej sól, stanowiąca 1-{3-[2-(1-benzotiofen-5-ylo)etoksy]propylo}-3-azetydynol lub jego sól PL217872B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2001321381 2001-10-19

Publications (2)

Publication Number Publication Date
PL402986A1 true PL402986A1 (pl) 2013-04-29
PL217872B1 PL217872B1 (pl) 2014-08-29

Family

ID=19138603

Family Applications (2)

Application Number Title Priority Date Filing Date
PL402986A PL217872B1 (pl) 2001-10-19 2002-10-18 Pochodna eteru alkilowego lub jej sól, stanowiąca 1-{3-[2-(1-benzotiofen-5-ylo)etoksy]propylo}-3-azetydynol lub jego sól
PL369601A PL215264B1 (pl) 2001-10-19 2002-10-18 Pochodne eteru alkilowego lub ich sole, sposób ich wytwarzania oraz kompozycja farmaceutyczna

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL369601A PL215264B1 (pl) 2001-10-19 2002-10-18 Pochodne eteru alkilowego lub ich sole, sposób ich wytwarzania oraz kompozycja farmaceutyczna

Country Status (23)

Country Link
US (4) USRE43676E1 (pl)
EP (1) EP1437353B1 (pl)
JP (1) JP4398247B2 (pl)
KR (1) KR100956990B1 (pl)
CN (2) CN101643470B (pl)
AT (1) ATE364604T1 (pl)
AU (1) AU2002344107B2 (pl)
BR (1) BRPI0213393B8 (pl)
CA (1) CA2464358C (pl)
CY (1) CY1106714T1 (pl)
DE (1) DE60220694T2 (pl)
DK (1) DK1437353T3 (pl)
ES (1) ES2287324T3 (pl)
HU (1) HU230407B1 (pl)
IL (2) IL161308A0 (pl)
MX (1) MXPA04003541A (pl)
NO (1) NO325780B1 (pl)
NZ (1) NZ532328A (pl)
PL (2) PL217872B1 (pl)
PT (1) PT1437353E (pl)
RO (1) RO122203B1 (pl)
WO (1) WO2003035647A1 (pl)
ZA (1) ZA200402806B (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0213393B8 (pt) * 2001-10-19 2021-05-25 Fujifilm Toyama Chemical Co Ltd derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica
SI2389937T1 (sl) * 2002-06-14 2018-10-30 Toyama Chemical Co., Ltd, Farmacevtska sestava za izboljšanje možganske funkcije
AU2004229283B2 (en) * 2003-04-17 2009-02-05 Toyama Chemical Co., Ltd. Preventive/remedy for retinal nerve diseases containing alkyl ether derivatives or salts thereof
AU2011204959B2 (en) * 2005-03-28 2012-04-12 Toyama Chemical Co., Ltd. Process for production of 1-(3-(2-(1-benzothiophen-5-YL)- ethoxy)propyl)azetidin-3-ol or salts thereof
PT2348022E (pt) 2005-03-28 2013-02-13 Toyama Chemical Co Ltd Processo para a produção de 1-(3-(2-(1- benzotiofen-5-il)etoxi)propil)azetidin-3-ol ou dos seus sais
JP4902247B2 (ja) * 2005-04-08 2012-03-21 富山化学工業株式会社 ２−（１−ベンゾチオフェン−５−イル）エタノールの新規製造法およびその中間体
JP2006328058A (ja) * 2005-04-27 2006-12-07 Toyama Chem Co Ltd ２−（１−ベンゾチオフェン−５−イル）エタノールの新規製造法およびその中間体
US8119625B2 (en) 2006-04-26 2012-02-21 Toyama Chemical Co., Ltd. Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof
SI2011796T1 (sl) * 2006-04-26 2015-02-27 Toyama Chemical Co., Ltd. Induktor nevrogeneze ali terapevtska uäśinkovina proti nevropatiji, vsebujoäśa derivat alkilnega etra ali sol le-tega
JP5255441B2 (ja) * 2006-08-04 2013-08-07 富山化学工業株式会社 アルキルエーテル誘導体またはその塩を含有するプロテインキナーゼｃ活性促進剤
SI2287160T1 (sl) * 2008-05-28 2014-09-30 Toyama Chemical Co., Ltd. Derivat benzotiofenovega oksida in sol le-tega
CN104159583B (zh) 2012-02-22 2018-04-13 富山化学工业株式会社 含有1‑(3‑(2‑(1‑苯并噻吩‑5‑基)乙氧基)丙基)氮杂环丁烷‑3‑醇或其盐的固体药物组合物
LT3100725T (lt) * 2014-01-31 2020-08-10 Fujifilm Toyama Chemical Co., Ltd. Reabilitacijos poveikį po nervo pažeidimo sustiprinanti priemonė, apimanti alkileterio darinį arba jo druską
EP3308782B1 (en) * 2015-06-11 2022-01-19 Toyama Chemical Co., Ltd. Sigma-receptor binding agent
KR102703879B1 (ko) 2015-12-25 2024-09-05 후지필름 도야마 케미컬 가부시키가이샤 1-(3-(2-(1-벤조티오펜-5-일)에톡시)프로필)아제티딘-3-올 또는 그 염을 포함하는 정제
JP7057286B2 (ja) 2016-12-28 2022-04-19 富士フイルム富山化学株式会社 医薬組成物
JP7176957B2 (ja) 2016-12-28 2022-11-22 富士フイルム富山化学株式会社 外用組成物
WO2018124284A1 (ja) 2016-12-28 2018-07-05 富山化学工業株式会社 医薬組成物
EP3563846B1 (en) 2016-12-28 2023-07-19 FUJIFILM Toyama Chemical Co., Ltd. Pharmaceutical composition and method for producing the same
WO2018221732A1 (ja) 2017-06-02 2018-12-06 富山化学工業株式会社 アミロイドβ蛋白質量減少剤
NZ759585A (en) * 2017-06-02 2022-02-25 Fujifilm Toyama Chemical Co Ltd Agent for preventing or treating brain atrophy
NZ759647A (en) 2017-06-02 2022-02-25 Fujifilm Toyama Chemical Co Ltd Agent for preventing or treating spinocerebellar ataxia
JPWO2018221728A1 (ja) 2017-06-02 2020-04-02 富士フイルム富山化学株式会社 アルツハイマー型認知症予防または治療剤
WO2018221731A1 (ja) 2017-06-02 2018-12-06 富山化学工業株式会社 タウオパチー予防または治療剤
US11548878B2 (en) 2017-10-30 2023-01-10 Fujifilm Toyama Chemical Co., Ltd. Emopamil binding protein binding agent and use thereof
CN114853619B (zh) * 2022-05-19 2024-05-10 神隆医药（常熟）有限公司 一种适于工业化生产的n-甲基酪胺盐酸盐的制备方法

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JP2887492B2 (ja) 1990-02-05 1999-04-26 富山化学工業株式会社 １，２―エタンジオール誘導体およびその塩
JP3044055B2 (ja) 1990-08-09 2000-05-22 富山化学工業株式会社 １，２―エタンジオール誘導体およびその塩
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SI2389937T1 (sl) 2002-06-14 2018-10-30 Toyama Chemical Co., Ltd, Farmacevtska sestava za izboljšanje možganske funkcije
AU2004229283B2 (en) 2003-04-17 2009-02-05 Toyama Chemical Co., Ltd. Preventive/remedy for retinal nerve diseases containing alkyl ether derivatives or salts thereof
PT2348022E (pt) 2005-03-28 2013-02-13 Toyama Chemical Co Ltd Processo para a produção de 1-(3-(2-(1- benzotiofen-5-il)etoxi)propil)azetidin-3-ol ou dos seus sais
US8119625B2 (en) 2006-04-26 2012-02-21 Toyama Chemical Co., Ltd. Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof
SI2011796T1 (sl) 2006-04-26 2015-02-27 Toyama Chemical Co., Ltd. Induktor nevrogeneze ali terapevtska uäśinkovina proti nevropatiji, vsebujoäśa derivat alkilnega etra ali sol le-tega
JP5255441B2 (ja) 2006-08-04 2013-08-07 富山化学工業株式会社 アルキルエーテル誘導体またはその塩を含有するプロテインキナーゼｃ活性促進剤
SI2287160T1 (sl) 2008-05-28 2014-09-30 Toyama Chemical Co., Ltd. Derivat benzotiofenovega oksida in sol le-tega

Also Published As

Publication number Publication date
PL217872B1 (pl) 2014-08-29
ZA200402806B (en) 2005-06-29
KR100956990B1 (ko) 2010-05-11
IL161308A (en) 2011-06-30
MXPA04003541A (es) 2004-07-22
NZ532328A (en) 2005-07-29
CN1571786A (zh) 2005-01-26
BRPI0213393B1 (pt) 2018-12-04
BR0213393A (pt) 2005-01-11
CN100500662C (zh) 2009-06-17
AU2002344107B2 (en) 2007-11-01
USRE43676E1 (en) 2012-09-18
ES2287324T3 (es) 2007-12-16
NO20041531L (no) 2004-04-15
US20050070521A1 (en) 2005-03-31
US7087594B2 (en) 2006-08-08
PT1437353E (pt) 2007-08-28
IL161308A0 (en) 2004-09-27
NO325780B1 (no) 2008-07-14
US7468443B2 (en) 2008-12-23
DE60220694T2 (de) 2008-02-07
DK1437353T3 (da) 2007-08-06
CA2464358A1 (en) 2003-05-01
HU230407B1 (hu) 2016-04-28
CA2464358C (en) 2011-05-24
HUP0500017A3 (en) 2011-07-28
KR20040050919A (ko) 2004-06-17
CY1106714T1 (el) 2012-05-23
WO2003035647A1 (fr) 2003-05-01
US20090111992A1 (en) 2009-04-30
PL215264B1 (pl) 2013-11-29
EP1437353B1 (en) 2007-06-13
US8129535B2 (en) 2012-03-06
RO122203B1 (ro) 2009-02-27
CN101643470B (zh) 2012-08-01
PL369601A1 (pl) 2005-05-02
JP4398247B2 (ja) 2010-01-13
US20060194781A1 (en) 2006-08-31
HUP0500017A2 (hu) 2005-04-28
DE60220694D1 (de) 2007-07-26
EP1437353A1 (en) 2004-07-14
CN101643470A (zh) 2010-02-10
EP1437353A4 (en) 2005-01-19
BRPI0213393B8 (pt) 2021-05-25
ATE364604T1 (de) 2007-07-15
JPWO2003035647A1 (ja) 2005-07-28

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