ATE364604T1 - Alkyletherderivate oder deren salze - Google Patents

Alkyletherderivate oder deren salze

Info

Publication number
ATE364604T1
ATE364604T1 AT02777882T AT02777882T ATE364604T1 AT E364604 T1 ATE364604 T1 AT E364604T1 AT 02777882 T AT02777882 T AT 02777882T AT 02777882 T AT02777882 T AT 02777882T AT E364604 T1 ATE364604 T1 AT E364604T1
Authority
AT
Austria
Prior art keywords
alkyl ether
ether derivatives
salts
new
optionally substituted
Prior art date
Application number
AT02777882T
Other languages
English (en)
Inventor
Akihito Saitoh
Noboru Iwakami
Tamotsu Takamatsu
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Application granted granted Critical
Publication of ATE364604T1 publication Critical patent/ATE364604T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
AT02777882T 2001-10-19 2002-10-18 Alkyletherderivate oder deren salze ATE364604T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2001321381 2001-10-19

Publications (1)

Publication Number Publication Date
ATE364604T1 true ATE364604T1 (de) 2007-07-15

Family

ID=19138603

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02777882T ATE364604T1 (de) 2001-10-19 2002-10-18 Alkyletherderivate oder deren salze

Country Status (23)

Country Link
US (4) USRE43676E1 (de)
EP (1) EP1437353B1 (de)
JP (1) JP4398247B2 (de)
KR (1) KR100956990B1 (de)
CN (2) CN100500662C (de)
AT (1) ATE364604T1 (de)
AU (1) AU2002344107B2 (de)
BR (1) BRPI0213393B8 (de)
CA (1) CA2464358C (de)
CY (1) CY1106714T1 (de)
DE (1) DE60220694T2 (de)
DK (1) DK1437353T3 (de)
ES (1) ES2287324T3 (de)
HU (1) HU230407B1 (de)
IL (2) IL161308A0 (de)
MX (1) MXPA04003541A (de)
NO (1) NO325780B1 (de)
NZ (1) NZ532328A (de)
PL (2) PL215264B1 (de)
PT (1) PT1437353E (de)
RO (1) RO122203B1 (de)
WO (1) WO2003035647A1 (de)
ZA (1) ZA200402806B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0213393B8 (pt) 2001-10-19 2021-05-25 Fujifilm Toyama Chemical Co Ltd derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica
SI1514542T1 (sl) * 2002-06-14 2012-06-29 Toyama Chemical Co Ltd Farmacevtska sestava, vsebujoäśa takrin ali donepezil za izboljĺ anje moĺ˝ganske funkcije
ZA200508166B (en) 2003-04-17 2007-03-28 Toyama Chemical Co Ltd Preventive/remedy for retinal nerve diseases containing alkyl ether derivatives or salts thereof
AU2011204959B2 (en) * 2005-03-28 2012-04-12 Toyama Chemical Co., Ltd. Process for production of 1-(3-(2-(1-benzothiophen-5-YL)- ethoxy)propyl)azetidin-3-ol or salts thereof
EP1864978A4 (de) * 2005-03-28 2009-07-01 Toyama Chemical Co Ltd Verfahren zur herstellung von 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol oder salzen davon
JP4902247B2 (ja) * 2005-04-08 2012-03-21 富山化学工業株式会社 2−(1−ベンゾチオフェン−5−イル)エタノールの新規製造法およびその中間体
JP2006328058A (ja) * 2005-04-27 2006-12-07 Toyama Chem Co Ltd 2−(1−ベンゾチオフェン−5−イル)エタノールの新規製造法およびその中間体
ZA200808728B (en) * 2006-04-26 2010-01-27 Toyama Chemical Co Ltd Neurogenesis inducer or neuropathy Therapeutic agent comprising alkyl ether derivative or salt thereof
US8119625B2 (en) * 2006-04-26 2012-02-21 Toyama Chemical Co., Ltd. Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof
ATE491705T1 (de) 2006-08-04 2011-01-15 Toyama Chemical Co Ltd Verstärker der aktivität von proteinkinase c, enthaltend ein alkyletherderivat oder ein salz davon
CN102046620B (zh) * 2008-05-28 2014-04-09 富山化学工业株式会社 新的苯并噻吩氧化物衍生物及其盐
US9872914B2 (en) 2012-02-22 2018-01-23 Toyama Chemical Co., Ltd. Solid pharmaceutical composition containing 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salt thereof
WO2015115582A1 (ja) * 2014-01-31 2015-08-06 富山化学工業株式会社 アルキルエーテル誘導体またはその塩を含有する神経損傷後のリハビリテーション効果促進剤
US10238632B2 (en) 2015-06-11 2019-03-26 Fujifilm Toyama Chemical Co., Ltd. Sigma receptor-binding agent
WO2017111005A1 (ja) 2015-12-25 2017-06-29 富山化学工業株式会社 1-(3-(2-(1-ベンゾチオフェン-5-イル)エトキシ)プロピル)アゼチジン-3-オールまたはその塩を含む錠剤
CN110139641B (zh) * 2016-12-28 2022-09-09 富士胶片富山化学株式会社 外用组合物
CN110167551B (zh) 2016-12-28 2022-06-14 富士胶片富山化学株式会社 医药组合物
CN110121342A (zh) 2016-12-28 2019-08-13 富士胶片富山化学株式会社 医药组合物
JP7079209B2 (ja) 2016-12-28 2022-06-01 富士フイルム富山化学株式会社 医薬組成物およびその製造方法
BR112019024878A2 (pt) 2017-06-02 2020-06-16 Fujifilm Toyama Chemical Co., Ltd. Agente para prevenção ou tratamento de tauopatia
EP3636262A4 (de) 2017-06-02 2020-06-10 FUJIFILM Toyama Chemical Co., Ltd. Mittel zur prävention und/oder behandlung von demenz vom alzheimertyp
JP7282028B2 (ja) * 2017-06-02 2023-05-26 富士フイルム富山化学株式会社 脳萎縮予防または治療剤
SG11201911519UA (en) * 2017-06-02 2020-01-30 Fujifilm Toyama Chemical Co Ltd AGENT FOR REDUCING AMOUNT OF AMYLOID ß PROTEIN
AU2018277981B2 (en) 2017-06-02 2021-04-08 Fujifilm Toyama Chemical Co., Ltd. Agent for preventing or treating spinocerebellar ataxia
JP7227914B2 (ja) 2017-10-30 2023-02-22 富士フイルム富山化学株式会社 エモパミル結合タンパク質結合剤およびその利用
CN114853619B (zh) * 2022-05-19 2024-05-10 神隆医药(常熟)有限公司 一种适于工业化生产的n-甲基酪胺盐酸盐的制备方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01156973A (ja) 1987-09-04 1989-06-20 Tanabe Seiyaku Co Ltd ベンゾフラン誘導体
JP2887492B2 (ja) 1990-02-05 1999-04-26 富山化学工業株式会社 1,2―エタンジオール誘導体およびその塩
JP3044055B2 (ja) 1990-08-09 2000-05-22 富山化学工業株式会社 1,2―エタンジオール誘導体およびその塩
DK74693D0 (da) 1993-06-23 1993-06-23 Novo Nordisk As Novel heterocyclic chemistry
JP3232830B2 (ja) 1993-11-30 2001-11-26 三菱電機株式会社 フレキシブルディスク装置のキャリッジ機構
EP1020427B1 (de) * 1994-10-25 2003-10-01 Toyama Chemical Co., Ltd. Ein Wirkstoff für die Forderung von Nervwachstumfaktor Aktivität, der ein 1,2-Ethandiol-Derivat oder ein Salz davon enthält
JPH08268883A (ja) 1994-10-25 1996-10-15 Toyama Chem Co Ltd 1−フェニル−1,2−エタンジオール誘導体またはそ の塩を含有する神経成長因子の作用増強剤
UA59341C2 (uk) 1995-08-11 2003-09-15 Пфайзер, Інк. (1s,2s)-1-(4-гідроксифеніл)-2-(4-гідрокси-4-фенілпіперидин-1-іл)-1-пропанолметансульфонат тригідрат
EP0873990A1 (de) 1995-09-22 1998-10-28 Yoshitomi Pharmaceutical Industries, Ltd. Benzoesäureverbindungen und ihre medizinische anwendung
DE19605610A1 (de) 1996-02-15 1997-08-21 Hoechst Ag Substituierte Thiophenylalkenylcarbonsäureguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
WO1997030703A1 (fr) 1996-02-20 1997-08-28 Toyama Chemical Co., Ltd. Agent ameliorant les fonctions cerebrales contenant des derives de 1,2-ethanediol ou des sels de celui-ci
JP4549452B2 (ja) 1997-12-12 2010-09-22 富山化学工業株式会社 アルキルエーテル誘導体またはその塩並びにそれらを含有するカルシウム拮抗剤
AU1506499A (en) * 1997-12-12 1999-07-05 Toyama Chemical Co. Ltd. Alkyl ether derivatives or salts thereof and calcium antagonists containing the same
DK1186594T3 (da) 1999-06-11 2009-09-14 Toyama Chemical Co Ltd N-alkoxylkyl-N,N-dialkylamin-derivater eller salte deraf og midler mod neurodegenerative sygdomme, som indeholder disse
BRPI0213393B8 (pt) 2001-10-19 2021-05-25 Fujifilm Toyama Chemical Co Ltd derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica
SI1514542T1 (sl) 2002-06-14 2012-06-29 Toyama Chemical Co Ltd Farmacevtska sestava, vsebujoäśa takrin ali donepezil za izboljĺ anje moĺ˝ganske funkcije
ZA200508166B (en) 2003-04-17 2007-03-28 Toyama Chemical Co Ltd Preventive/remedy for retinal nerve diseases containing alkyl ether derivatives or salts thereof
EP1864978A4 (de) 2005-03-28 2009-07-01 Toyama Chemical Co Ltd Verfahren zur herstellung von 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol oder salzen davon
ZA200808728B (en) 2006-04-26 2010-01-27 Toyama Chemical Co Ltd Neurogenesis inducer or neuropathy Therapeutic agent comprising alkyl ether derivative or salt thereof
US8119625B2 (en) 2006-04-26 2012-02-21 Toyama Chemical Co., Ltd. Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof
ATE491705T1 (de) 2006-08-04 2011-01-15 Toyama Chemical Co Ltd Verstärker der aktivität von proteinkinase c, enthaltend ein alkyletherderivat oder ein salz davon
CN102046620B (zh) 2008-05-28 2014-04-09 富山化学工业株式会社 新的苯并噻吩氧化物衍生物及其盐

Also Published As

Publication number Publication date
US20050070521A1 (en) 2005-03-31
EP1437353A4 (de) 2005-01-19
HUP0500017A2 (hu) 2005-04-28
PL402986A1 (pl) 2013-04-29
WO2003035647A1 (fr) 2003-05-01
DK1437353T3 (da) 2007-08-06
BR0213393A (pt) 2005-01-11
NO325780B1 (no) 2008-07-14
US20060194781A1 (en) 2006-08-31
IL161308A0 (en) 2004-09-27
US7087594B2 (en) 2006-08-08
BRPI0213393B8 (pt) 2021-05-25
EP1437353A1 (de) 2004-07-14
CN101643470A (zh) 2010-02-10
AU2002344107B2 (en) 2007-11-01
MXPA04003541A (es) 2004-07-22
ES2287324T3 (es) 2007-12-16
DE60220694T2 (de) 2008-02-07
CN100500662C (zh) 2009-06-17
KR20040050919A (ko) 2004-06-17
ZA200402806B (en) 2005-06-29
PT1437353E (pt) 2007-08-28
EP1437353B1 (de) 2007-06-13
CA2464358C (en) 2011-05-24
KR100956990B1 (ko) 2010-05-11
USRE43676E1 (en) 2012-09-18
BRPI0213393B1 (pt) 2018-12-04
US20090111992A1 (en) 2009-04-30
IL161308A (en) 2011-06-30
DE60220694D1 (de) 2007-07-26
JPWO2003035647A1 (ja) 2005-07-28
NO20041531L (no) 2004-04-15
HU230407B1 (hu) 2016-04-28
JP4398247B2 (ja) 2010-01-13
NZ532328A (en) 2005-07-29
CA2464358A1 (en) 2003-05-01
US7468443B2 (en) 2008-12-23
PL215264B1 (pl) 2013-11-29
US8129535B2 (en) 2012-03-06
CN1571786A (zh) 2005-01-26
CN101643470B (zh) 2012-08-01
CY1106714T1 (el) 2012-05-23
RO122203B1 (ro) 2009-02-27
HUP0500017A3 (en) 2011-07-28
PL217872B1 (pl) 2014-08-29
PL369601A1 (en) 2005-05-02

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