NL1002248C2 - Nieuwe verbindingen. - Google Patents

Nieuwe verbindingen.

Info

Publication number
NL1002248C2
NL1002248C2 NL1002248A NL1002248A NL1002248C2 NL 1002248 C2 NL1002248 C2 NL 1002248C2 NL 1002248 A NL1002248 A NL 1002248A NL 1002248 A NL1002248 A NL 1002248A NL 1002248 C2 NL1002248 C2 NL 1002248C2
Authority
NL
Netherlands
Prior art keywords
new connections
connections
new
Prior art date
Application number
NL1002248A
Other languages
English (en)
Dutch (nl)
Other versions
NL1002248A1 (nl
Inventor
Victor Witold Jacewicz
Neal Ward
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27267578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL1002248(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9502297.6A external-priority patent/GB9502297D0/en
Priority claimed from GBGB9503112.6A external-priority patent/GB9503112D0/en
Priority claimed from GBGB9509807.5A external-priority patent/GB9509807D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NL1002248A1 publication Critical patent/NL1002248A1/xx
Application granted granted Critical
Publication of NL1002248C2 publication Critical patent/NL1002248C2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL1002248A 1995-02-06 1996-02-05 Nieuwe verbindingen. NL1002248C2 (nl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9502297.6A GB9502297D0 (en) 1995-02-06 1995-02-06 Novel compound
GBGB9503112.6A GB9503112D0 (en) 1995-02-17 1995-02-17 Novel compound
GBGB9509807.5A GB9509807D0 (en) 1995-05-15 1995-05-15 Novel compounds

Publications (2)

Publication Number Publication Date
NL1002248A1 NL1002248A1 (nl) 1996-08-06
NL1002248C2 true NL1002248C2 (nl) 1996-09-11

Family

ID=27267578

Family Applications (1)

Application Number Title Priority Date Filing Date
NL1002248A NL1002248C2 (nl) 1995-02-06 1996-02-05 Nieuwe verbindingen.

Country Status (47)

Country Link
EP (3) EP0808314B1 (de)
JP (2) JP2915338B2 (de)
KR (1) KR100289885B1 (de)
CN (3) CN1090187C (de)
AR (2) AR001982A1 (de)
AT (1) AT407528B (de)
AU (2) AU701518C (de)
BE (1) BE1009112A3 (de)
BG (1) BG62967B1 (de)
BR (1) BR9600534A (de)
CA (4) CA2210023C (de)
CH (3) CH688353A5 (de)
CZ (1) CZ297171B6 (de)
DE (3) DE19603797C2 (de)
DK (2) DK11996A (de)
DZ (1) DZ1989A1 (de)
ES (1) ES2114471B1 (de)
FI (3) FI111544B (de)
FR (1) FR2730232B1 (de)
GR (1) GR1002466B (de)
HK (1) HK59397A (de)
HU (1) HUP9600255A1 (de)
IE (1) IE80500B1 (de)
IL (1) IL117035A (de)
IT (1) IT1289532B1 (de)
LU (1) LU88711A1 (de)
LV (1) LV11618B (de)
MA (1) MA23802A1 (de)
MC (1) MC2411A1 (de)
MX (1) MX9600484A (de)
MY (1) MY132529A (de)
NL (1) NL1002248C2 (de)
NO (3) NO301009B1 (de)
NZ (1) NZ280943A (de)
OA (1) OA10261A (de)
PL (1) PL189247B1 (de)
PT (1) PT101827B (de)
RO (1) RO112426B1 (de)
RU (1) RU2125052C1 (de)
SE (1) SE521084C2 (de)
SG (1) SG43787A1 (de)
SI (2) SI21923B (de)
SK (1) SK283608B6 (de)
TR (1) TR199600096A2 (de)
TW (1) TW503238B (de)
UA (1) UA49796C2 (de)
WO (1) WO1996024595A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3882224B2 (ja) 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
EP1384720A1 (de) * 1996-06-13 2004-01-28 SUMIKA FINE CHEMICALS Co., Ltd. Verfahren zur Trocknung von Paroxetinhydrochlorid
JP2000514653A (ja) * 1996-07-15 2000-11-07 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 立体特異的分割のためのエステラーゼのスクリーニングおよびその使用
US6638948B1 (en) 1996-09-09 2003-10-28 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
US5672612A (en) * 1996-09-09 1997-09-30 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
CA2193939C (en) * 1996-12-24 2002-02-12 K.S. Keshava Murthy Useful form of anhydrous paroxetine hydrochloride
ES2155995T3 (es) * 1997-06-10 2001-06-01 Synthon Bv Compuestos de 4-fenilpiperidina.
EP0903345B1 (de) * 1997-08-08 2000-10-04 Aventis Pharma Deutschland GmbH Kristallform von 5-Methylisoxazol-4-carbonsäure-(4-trifluormethyl)-anilid
GB9726907D0 (en) * 1997-12-19 1998-02-18 Smithkline Beecham Plc Novel compounds
SK13622000A3 (sk) * 1998-03-16 2001-03-12 Smithkline Beecham Plc Kryštalická forma paroxetínu, farmaceutický prostriedok a použitie
AU2003200534B2 (en) * 1998-03-24 2004-12-02 Smithkline Beecham Plc Paroxetine compositions
US6699882B2 (en) 1998-03-24 2004-03-02 Smithkline Beecham P.L.C. Paroxetine compositions
GB9806312D0 (en) * 1998-03-24 1998-05-20 Smithkline Beecham Plc Novel formulations
JP3796351B2 (ja) 1998-04-13 2006-07-12 住友化学株式会社 パロキセチン塩酸塩無水和物の乾燥方法
GB9812941D0 (en) * 1998-06-16 1998-08-12 Smithkline Beecham Plc Method of treatment
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
ES2138937B1 (es) 1998-07-07 2000-10-01 Medichem Sa Polimorfo de maleato de paroxetina y formulaciones farmaceuticas que lo contienen.
ID27914A (id) * 1998-08-07 2001-05-03 Smithkline Beecham Plc Proses untuk penyiapan bentuk anhidrat paroksetina hidroklorida bukan kristal
GB9824298D0 (en) * 1998-11-05 1998-12-30 Smithkline Beecham Plc Novel process
GB9826175D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
GB9826176D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
GB9826178D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
DE69913377T2 (de) * 1998-11-30 2004-12-30 Smithkline Beecham P.L.C., Brentford Gemischte Paroxetin-Propan-2-ol-Solvate
GB9826171D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel compounds
GB9826180D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9826242D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9828767D0 (en) * 1998-12-29 1999-02-17 Smithkline Beecham Plc Novel process
ATE311883T1 (de) * 1999-03-12 2005-12-15 Aesica Pharmaceuticals Ltd Stabile pharmazeutische anwendungsform für paroxetin-anhydrat
GB9914583D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
GB9914585D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
GB9919001D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel process
GB9923446D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923445D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
HU226912B1 (en) * 2000-04-07 2010-03-01 Richter Gedeon Nyrt New paroxetin salt and medicament containing it
AU2001286232A1 (en) * 2000-09-14 2002-03-26 Asahi Glass Company, Limited Process for producing paroxetine salt containing substantially no organic solvent
AU2002259114A1 (en) * 2002-02-22 2003-09-09 Teva Pharmaceutical Industries Ltd. Preparation of paroxetine involving novel intermediates
WO2007062147A1 (en) * 2005-11-22 2007-05-31 Teva Pharmaceutical Industries Ltd. Crystal forms of cinacalcet hci and processes for their preparation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0223403A2 (de) * 1985-10-25 1987-05-27 Beecham Group Plc Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
GB8430581D0 (en) * 1984-12-04 1985-01-09 Ferrosan As Treatment
GB8626936D0 (en) * 1986-11-11 1986-12-10 Ferrosan As Treatment
DK715988D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Etherifikation og dealkylering af piperidin-derivater samt intermediater
DK716088D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Reduktion af piperidin-dion-derivater samt intermediat
EP0558679A1 (de) * 1990-11-24 1993-09-08 BEECHAM GROUP plc Verwendung von paroxetin zur behandlung von seniler demenz, bulimia, migräne oder anorexia
GB9325644D0 (en) * 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0223403A2 (de) * 1985-10-25 1987-05-27 Beecham Group Plc Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
P. CHRISTOPHER BUXTON ET AL.: "Solid-State Forms of Paroxetine Hydrochloride", INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 42, 1988, AMSTERDAM NL, pages 135 - 143, XP000572028 *

Also Published As

Publication number Publication date
PT101827B (pt) 1997-08-29
NO20015070L (no) 1996-08-07
NO970939D0 (no) 1997-02-28
ATA21096A (de) 2000-08-15
SE9600406D0 (sv) 1996-02-05
SI21923B (sl) 2006-12-31
MX198371B (de) 2000-08-29
LU88711A1 (fr) 1996-08-23
BG100333A (bg) 1996-08-30
HU9600255D0 (en) 1996-03-28
SE9600406L (sv) 1996-08-07
PL189247B1 (pl) 2005-07-29
DE69631298T2 (de) 2004-11-18
SK283608B6 (sk) 2003-10-07
FI20030370A (fi) 2003-03-12
IE80500B1 (en) 1998-08-12
CZ32096A3 (en) 1996-08-14
EP1378508A1 (de) 2004-01-07
FI111544B (fi) 2003-08-15
SG43787A1 (en) 1997-11-14
CA2211522A1 (en) 1996-08-07
DK200100223A (de) 2001-02-12
AU4332896A (en) 1996-08-15
CN1216055C (zh) 2005-08-24
SI9600036A (en) 1996-10-31
ES2114471B1 (es) 1999-08-16
RU2125052C1 (ru) 1999-01-20
BG62967B1 (bg) 2000-12-29
CA2210023A1 (en) 1996-08-07
NO301009B3 (de) 2003-01-06
CA2210023C (en) 1999-02-09
TR199600096A2 (tr) 1996-08-21
CA2168829C (en) 1997-12-16
IL117035A (en) 2000-02-29
RO112426B1 (ro) 1997-09-30
OA10261A (en) 1997-09-19
CN1289496C (zh) 2006-12-13
FI960519A (fi) 1996-08-07
CA2210022C (en) 2005-09-13
NL1002248A1 (nl) 1996-08-06
CH689229A5 (de) 1998-12-31
NO960472L (no) 1996-08-07
JP2915338B2 (ja) 1999-07-05
MX9600484A (es) 1997-01-31
FR2730232A1 (fr) 1996-08-09
MC2411A1 (fr) 1996-12-02
EP1136490B1 (de) 2004-01-07
EP0808314B1 (de) 2002-06-12
ES2114471A1 (es) 1998-05-16
EP0808314A1 (de) 1997-11-26
CA2168829A1 (en) 1996-08-07
HUP9600255A1 (en) 1997-03-28
DE69621777D1 (de) 2002-07-18
FI960519A0 (fi) 1996-02-05
NO301009B1 (no) 1997-09-01
BR9600534A (pt) 1997-05-13
DE19603797A1 (de) 1996-08-14
CN1310180A (zh) 2001-08-29
MY132529A (en) 2007-10-31
LV11618B (en) 1997-04-20
NZ280943A (en) 1997-01-29
FI20030162A (fi) 2003-02-03
AU701518B2 (en) 1999-01-28
CH688353A5 (de) 1997-08-15
SI9600036B (sl) 2006-12-31
NO960472D0 (no) 1996-02-05
ITMI960203A1 (it) 1997-08-05
CA2211522C (en) 1999-12-07
DE19603797C2 (de) 1998-11-12
IT1289532B1 (it) 1998-10-15
PT101827A (pt) 1996-09-30
MA23802A1 (fr) 1996-10-01
AR036856A2 (es) 2004-10-06
AT407528B (de) 2001-04-25
GR1002466B (el) 1996-11-06
NO970939L (no) 1996-08-07
NO311519B1 (no) 2001-12-03
CA2210022A1 (en) 1996-08-07
JPH08245620A (ja) 1996-09-24
CN1143643A (zh) 1997-02-26
DE69631298D1 (de) 2004-02-12
AU701518C (en) 2006-12-07
CH689804A5 (de) 1999-11-30
NO20015070D0 (no) 2001-10-18
AU4786496A (en) 1996-08-27
DE69621777T2 (de) 2003-01-02
SE521084C2 (sv) 2003-09-30
UA49796C2 (uk) 2002-10-15
DK11996A (da) 1996-08-07
DZ1989A1 (fr) 2002-10-15
HK59397A (en) 1997-05-16
AR001982A1 (es) 1998-01-07
SK14396A3 (en) 1996-11-06
WO1996024595A1 (en) 1996-08-15
FR2730232B1 (fr) 1997-08-01
IE960104A1 (en) 1996-08-07
CN1090187C (zh) 2002-09-04
TW503238B (en) 2002-09-21
JPH11228571A (ja) 1999-08-24
CZ297171B6 (cs) 2006-09-13
IL117035A0 (en) 1996-09-12
PL312646A1 (en) 1996-08-19
KR100289885B1 (ko) 2001-05-15
KR960031409A (ko) 1996-09-17
EP1136490A1 (de) 2001-09-26
SI21923A (sl) 2006-06-30
LV11618A (lv) 1996-12-20
CN1636993A (zh) 2005-07-13
BE1009112A3 (fr) 1996-11-05
ITMI960203A0 (de) 1996-02-05

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