AR001982A1 - Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion - Google Patents

Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion

Info

Publication number
AR001982A1
AR001982A1 ARP960101230A AR10123096A AR001982A1 AR 001982 A1 AR001982 A1 AR 001982A1 AR P960101230 A ARP960101230 A AR P960101230A AR 10123096 A AR10123096 A AR 10123096A AR 001982 A1 AR001982 A1 AR 001982A1
Authority
AR
Argentina
Prior art keywords
preparation
paroxetine
anhydrated
chlorhydrate
procedure
Prior art date
Application number
ARP960101230A
Other languages
English (en)
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27267578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR001982(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9502297.6A external-priority patent/GB9502297D0/en
Priority claimed from GBGB9503112.6A external-priority patent/GB9503112D0/en
Priority claimed from GBGB9509807.5A external-priority patent/GB9509807D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of AR001982A1 publication Critical patent/AR001982A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents

Abstract

Un clorhidrato de paroxetina anhidratado, solvatos del mismo y procedimientos para su preparación, en donde el clorhidrato de paroxetina estásubstancialmente libre de propan-2-ol asociado, diversas formas del mismo, procedimientosp ara la preparación del mismo.
ARP960101230A 1995-02-06 1996-02-01 Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion AR001982A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9502297.6A GB9502297D0 (en) 1995-02-06 1995-02-06 Novel compound
GBGB9503112.6A GB9503112D0 (en) 1995-02-17 1995-02-17 Novel compound
GBGB9509807.5A GB9509807D0 (en) 1995-05-15 1995-05-15 Novel compounds

Publications (1)

Publication Number Publication Date
AR001982A1 true AR001982A1 (es) 1998-01-07

Family

ID=27267578

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP960101230A AR001982A1 (es) 1995-02-06 1996-02-01 Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion
ARP020103931A AR036856A2 (es) 1995-02-06 2002-10-18 Clorhidrato de paroxetina anhidro, y procedimiento para su preparacion

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP020103931A AR036856A2 (es) 1995-02-06 2002-10-18 Clorhidrato de paroxetina anhidro, y procedimiento para su preparacion

Country Status (47)

Country Link
EP (3) EP1136490B1 (es)
JP (2) JP2915338B2 (es)
KR (1) KR100289885B1 (es)
CN (3) CN1289496C (es)
AR (2) AR001982A1 (es)
AT (1) AT407528B (es)
AU (2) AU701518C (es)
BE (1) BE1009112A3 (es)
BG (1) BG62967B1 (es)
BR (1) BR9600534A (es)
CA (4) CA2210022C (es)
CH (3) CH689804A5 (es)
CZ (1) CZ297171B6 (es)
DE (3) DE69631298T2 (es)
DK (2) DK11996A (es)
DZ (1) DZ1989A1 (es)
ES (1) ES2114471B1 (es)
FI (3) FI111544B (es)
FR (1) FR2730232B1 (es)
GR (1) GR1002466B (es)
HK (1) HK59397A (es)
HU (1) HUP9600255A1 (es)
IE (1) IE80500B1 (es)
IL (1) IL117035A (es)
IT (1) IT1289532B1 (es)
LU (1) LU88711A1 (es)
LV (1) LV11618B (es)
MA (1) MA23802A1 (es)
MC (1) MC2411A1 (es)
MX (1) MX9600484A (es)
MY (1) MY132529A (es)
NL (1) NL1002248C2 (es)
NO (3) NO301009B1 (es)
NZ (1) NZ280943A (es)
OA (1) OA10261A (es)
PL (1) PL189247B1 (es)
PT (1) PT101827B (es)
RO (1) RO112426B1 (es)
RU (1) RU2125052C1 (es)
SE (1) SE521084C2 (es)
SG (1) SG43787A1 (es)
SI (2) SI21923B (es)
SK (1) SK283608B6 (es)
TR (1) TR199600096A2 (es)
TW (1) TW503238B (es)
UA (1) UA49796C2 (es)
WO (1) WO1996024595A1 (es)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3882224B2 (ja) 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
DE69739561D1 (de) 1996-06-13 2009-10-15 Sumitomo Chemical Co Piperidin Derivative als Zwischenprodukte zur Herstellung von Paroxetine und Verfahren zu ihrer Herstellung
JP2000514653A (ja) * 1996-07-15 2000-11-07 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 立体特異的分割のためのエステラーゼのスクリーニングおよびその使用
US6638948B1 (en) 1996-09-09 2003-10-28 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
US5672612A (en) * 1996-09-09 1997-09-30 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
CA2193939C (en) * 1996-12-24 2002-02-12 K.S. Keshava Murthy Useful form of anhydrous paroxetine hydrochloride
BR9714787A (pt) * 1997-06-10 2000-07-18 Synthon Bv Compostos de 4- fenilpiperidina e processo para sua preparação
EP0987256B1 (de) * 1997-08-08 2001-10-17 Aventis Pharma Deutschland GmbH Kristallform von N-(4-Trifluormethylphenyl)-5-methylisoxazol-4-carbonsäureamid
GB9726907D0 (en) * 1997-12-19 1998-02-18 Smithkline Beecham Plc Novel compounds
PL342931A1 (en) * 1998-03-16 2001-07-16 Smithkline Beecham Plc Crystalline form of paroxetine
US6699882B2 (en) 1998-03-24 2004-03-02 Smithkline Beecham P.L.C. Paroxetine compositions
GB9806312D0 (en) * 1998-03-24 1998-05-20 Smithkline Beecham Plc Novel formulations
AU2003200534B2 (en) * 1998-03-24 2004-12-02 Smithkline Beecham Plc Paroxetine compositions
JP3796351B2 (ja) * 1998-04-13 2006-07-12 住友化学株式会社 パロキセチン塩酸塩無水和物の乾燥方法
GB9812941D0 (en) * 1998-06-16 1998-08-12 Smithkline Beecham Plc Method of treatment
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
ES2138937B1 (es) 1998-07-07 2000-10-01 Medichem Sa Polimorfo de maleato de paroxetina y formulaciones farmaceuticas que lo contienen.
PT1100796E (pt) * 1998-08-07 2003-09-30 Smithkline Beecham Plc Processo para a preparacao de um cloridrato de paroxetina na forma anidra nao cristalina
GB9824298D0 (en) * 1998-11-05 1998-12-30 Smithkline Beecham Plc Novel process
GB9826175D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
GB9826176D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
ES2211232T3 (es) * 1998-11-30 2004-07-01 Smithkline Beecham Plc Solvatos mixtos de paroxetina-propan-2-ol.
GB9826180D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9826171D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel compounds
GB9826178D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9826242D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9828767D0 (en) * 1998-12-29 1999-02-17 Smithkline Beecham Plc Novel process
JP4854115B2 (ja) * 1999-03-12 2012-01-18 エイシカ ファーマシューティカルス リミテッド 無水パロキセチン用安定製剤形
GB9914583D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
GB9914585D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
GB9919001D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel process
GB9923446D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923445D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
HU226912B1 (en) * 2000-04-07 2010-03-01 Richter Gedeon Nyrt New paroxetin salt and medicament containing it
WO2002022609A1 (fr) * 2000-09-14 2002-03-21 Asahi Glass Company, Limited Procede de production de sel de paroxetine sensiblement exempt de solvant organique
IL163593A0 (en) * 2002-02-22 2005-12-18 Teva Pharma Preparation of paroxetine involving novel intermediates
EP1828098A1 (en) * 2005-11-22 2007-09-05 Teva Pharmaceutical Industries Ltd Crystal forms of cinacalcet hci and processes for their preparation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
GB8430581D0 (en) * 1984-12-04 1985-01-09 Ferrosan As Treatment
EP0223403B1 (en) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidine derivative, its preparation, and its use as medicament
GB8626936D0 (en) * 1986-11-11 1986-12-10 Ferrosan As Treatment
DK716088D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Reduktion af piperidin-dion-derivater samt intermediat
DK715988D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Etherifikation og dealkylering af piperidin-derivater samt intermediater
AU658155B2 (en) * 1990-11-24 1995-04-06 Beecham Group Plc Use of paroxetine for the treatment of senile dementia, or anorexia
GB9325644D0 (en) * 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation

Also Published As

Publication number Publication date
FR2730232A1 (fr) 1996-08-09
EP0808314A1 (en) 1997-11-26
ES2114471B1 (es) 1999-08-16
CZ297171B6 (cs) 2006-09-13
FI20030370A (fi) 2003-03-12
CH689229A5 (de) 1998-12-31
ITMI960203A0 (es) 1996-02-05
IE960104A1 (en) 1996-08-07
NL1002248C2 (nl) 1996-09-11
CA2210022C (en) 2005-09-13
RO112426B1 (ro) 1997-09-30
PT101827B (pt) 1997-08-29
NO301009B1 (no) 1997-09-01
MC2411A1 (fr) 1996-12-02
EP1378508A1 (en) 2004-01-07
NO311519B1 (no) 2001-12-03
ATA21096A (de) 2000-08-15
ITMI960203A1 (it) 1997-08-05
JPH11228571A (ja) 1999-08-24
CN1143643A (zh) 1997-02-26
FI960519A0 (fi) 1996-02-05
PL189247B1 (pl) 2005-07-29
NO20015070D0 (no) 2001-10-18
CA2168829C (en) 1997-12-16
SE9600406D0 (sv) 1996-02-05
AU701518B2 (en) 1999-01-28
FI20030162A (fi) 2003-02-03
BG100333A (bg) 1996-08-30
AU701518C (en) 2006-12-07
CA2168829A1 (en) 1996-08-07
CH688353A5 (de) 1997-08-15
AU4332896A (en) 1996-08-15
JPH08245620A (ja) 1996-09-24
MX9600484A (es) 1997-01-31
EP1136490A1 (en) 2001-09-26
OA10261A (en) 1997-09-19
AU4786496A (en) 1996-08-27
CN1310180A (zh) 2001-08-29
SE521084C2 (sv) 2003-09-30
UA49796C2 (uk) 2002-10-15
TR199600096A2 (tr) 1996-08-21
SI21923B (sl) 2006-12-31
GR1002466B (el) 1996-11-06
FI960519A (fi) 1996-08-07
MA23802A1 (fr) 1996-10-01
CA2210022A1 (en) 1996-08-07
SI9600036A (en) 1996-10-31
DE19603797C2 (de) 1998-11-12
CH689804A5 (de) 1999-11-30
MY132529A (en) 2007-10-31
CN1216055C (zh) 2005-08-24
SK283608B6 (sk) 2003-10-07
NL1002248A1 (nl) 1996-08-06
SE9600406L (sv) 1996-08-07
MX198371B (es) 2000-08-29
SK14396A3 (en) 1996-11-06
NO960472D0 (no) 1996-02-05
CA2211522A1 (en) 1996-08-07
CA2211522C (en) 1999-12-07
NZ280943A (en) 1997-01-29
EP1136490B1 (en) 2004-01-07
DE69631298T2 (de) 2004-11-18
SI9600036B (sl) 2006-12-31
KR960031409A (ko) 1996-09-17
FR2730232B1 (fr) 1997-08-01
HK59397A (en) 1997-05-16
TW503238B (en) 2002-09-21
SI21923A (sl) 2006-06-30
CA2210023A1 (en) 1996-08-07
SG43787A1 (en) 1997-11-14
AT407528B (de) 2001-04-25
DE69621777D1 (de) 2002-07-18
FI111544B (fi) 2003-08-15
NO20015070L (no) 1996-08-07
DK11996A (da) 1996-08-07
DZ1989A1 (fr) 2002-10-15
IT1289532B1 (it) 1998-10-15
CZ32096A3 (en) 1996-08-14
DE19603797A1 (de) 1996-08-14
DK200100223A (es) 2001-02-12
NO960472L (no) 1996-08-07
JP2915338B2 (ja) 1999-07-05
DE69621777T2 (de) 2003-01-02
HU9600255D0 (en) 1996-03-28
IE80500B1 (en) 1998-08-12
CN1289496C (zh) 2006-12-13
NO970939D0 (no) 1997-02-28
NO970939L (no) 1996-08-07
LV11618A (lv) 1996-12-20
PT101827A (pt) 1996-09-30
ES2114471A1 (es) 1998-05-16
KR100289885B1 (ko) 2001-05-15
EP0808314B1 (en) 2002-06-12
IL117035A0 (en) 1996-09-12
AR036856A2 (es) 2004-10-06
LV11618B (en) 1997-04-20
CN1636993A (zh) 2005-07-13
HUP9600255A1 (en) 1997-03-28
NO301009B3 (es) 2003-01-06
IL117035A (en) 2000-02-29
BE1009112A3 (fr) 1996-11-05
BR9600534A (pt) 1997-05-13
BG62967B1 (bg) 2000-12-29
LU88711A1 (fr) 1996-08-23
CN1090187C (zh) 2002-09-04
WO1996024595A1 (en) 1996-08-15
PL312646A1 (en) 1996-08-19
CA2210023C (en) 1999-02-09
DE69631298D1 (de) 2004-02-12
RU2125052C1 (ru) 1999-01-20

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