BG62967B1 - Пароксетин хидрохлорид анхидрат - Google Patents

Пароксетин хидрохлорид анхидрат Download PDF

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Publication number
BG62967B1
BG62967B1 BG100333A BG10033396A BG62967B1 BG 62967 B1 BG62967 B1 BG 62967B1 BG 100333 A BG100333 A BG 100333A BG 10033396 A BG10033396 A BG 10033396A BG 62967 B1 BG62967 B1 BG 62967B1
Authority
BG
Bulgaria
Prior art keywords
paroxetine hydrochloride
solvate
hydrochloride anhydrate
anhydrate
propan
Prior art date
Application number
BG100333A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100333A (bg
Inventor
Victor JACEWICZ
Neal Ward
Original Assignee
Smithkline Beecham P.L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27267578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG62967(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9502297.6A external-priority patent/GB9502297D0/en
Priority claimed from GBGB9503112.6A external-priority patent/GB9503112D0/en
Priority claimed from GBGB9509807.5A external-priority patent/GB9509807D0/en
Application filed by Smithkline Beecham P.L.C. filed Critical Smithkline Beecham P.L.C.
Publication of BG100333A publication Critical patent/BG100333A/bg
Publication of BG62967B1 publication Critical patent/BG62967B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG100333A 1995-02-06 1996-02-05 Пароксетин хидрохлорид анхидрат BG62967B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9502297.6A GB9502297D0 (en) 1995-02-06 1995-02-06 Novel compound
GBGB9503112.6A GB9503112D0 (en) 1995-02-17 1995-02-17 Novel compound
GBGB9509807.5A GB9509807D0 (en) 1995-05-15 1995-05-15 Novel compounds

Publications (2)

Publication Number Publication Date
BG100333A BG100333A (bg) 1996-08-30
BG62967B1 true BG62967B1 (bg) 2000-12-29

Family

ID=27267578

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100333A BG62967B1 (bg) 1995-02-06 1996-02-05 Пароксетин хидрохлорид анхидрат

Country Status (47)

Country Link
EP (3) EP0808314B1 (es)
JP (2) JP2915338B2 (es)
KR (1) KR100289885B1 (es)
CN (3) CN1090187C (es)
AR (2) AR001982A1 (es)
AT (1) AT407528B (es)
AU (2) AU4786496A (es)
BE (1) BE1009112A3 (es)
BG (1) BG62967B1 (es)
BR (1) BR9600534A (es)
CA (4) CA2211522C (es)
CH (3) CH689804A5 (es)
CZ (1) CZ297171B6 (es)
DE (3) DE19603797C2 (es)
DK (2) DK11996A (es)
DZ (1) DZ1989A1 (es)
ES (1) ES2114471B1 (es)
FI (3) FI111544B (es)
FR (1) FR2730232B1 (es)
GR (1) GR1002466B (es)
HK (1) HK59397A (es)
HU (1) HUP9600255A1 (es)
IE (1) IE80500B1 (es)
IL (1) IL117035A (es)
IT (1) IT1289532B1 (es)
LU (1) LU88711A1 (es)
LV (1) LV11618B (es)
MA (1) MA23802A1 (es)
MC (1) MC2411A1 (es)
MX (1) MX9600484A (es)
MY (1) MY132529A (es)
NL (1) NL1002248C2 (es)
NO (3) NO301009B1 (es)
NZ (1) NZ280943A (es)
OA (1) OA10261A (es)
PL (1) PL189247B1 (es)
PT (1) PT101827B (es)
RO (1) RO112426B1 (es)
RU (1) RU2125052C1 (es)
SE (1) SE521084C2 (es)
SG (1) SG43787A1 (es)
SI (2) SI21923B (es)
SK (1) SK283608B6 (es)
TR (1) TR199600096A2 (es)
TW (1) TW503238B (es)
UA (1) UA49796C2 (es)
WO (1) WO1996024595A1 (es)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3882224B2 (ja) 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
EP1384720A1 (en) * 1996-06-13 2004-01-28 SUMIKA FINE CHEMICALS Co., Ltd. Process for drying paroxetine hydrochloride
EP0937152A2 (en) * 1996-07-15 1999-08-25 Smithkline Beecham Plc Screening for and use of an esterase for a stereospecific resolution
US6638948B1 (en) 1996-09-09 2003-10-28 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
US5672612A (en) * 1996-09-09 1997-09-30 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
CA2193939C (en) * 1996-12-24 2002-02-12 K.S. Keshava Murthy Useful form of anhydrous paroxetine hydrochloride
DK0994872T3 (da) 1997-06-10 2001-05-28 Synthon Bv 4-phenylpiperidin-forbindelser
EP0987256B1 (de) * 1997-08-08 2001-10-17 Aventis Pharma Deutschland GmbH Kristallform von N-(4-Trifluormethylphenyl)-5-methylisoxazol-4-carbonsäureamid
GB9726907D0 (en) * 1997-12-19 1998-02-18 Smithkline Beecham Plc Novel compounds
CN1300286A (zh) * 1998-03-16 2001-06-20 史密丝克莱恩比彻姆有限公司 帕罗西丁的晶形
AU2003200534B2 (en) * 1998-03-24 2004-12-02 Smithkline Beecham Plc Paroxetine compositions
US6699882B2 (en) 1998-03-24 2004-03-02 Smithkline Beecham P.L.C. Paroxetine compositions
GB9806312D0 (en) * 1998-03-24 1998-05-20 Smithkline Beecham Plc Novel formulations
JP3796351B2 (ja) * 1998-04-13 2006-07-12 住友化学株式会社 パロキセチン塩酸塩無水和物の乾燥方法
GB9812941D0 (en) * 1998-06-16 1998-08-12 Smithkline Beecham Plc Method of treatment
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
ES2138937B1 (es) 1998-07-07 2000-10-01 Medichem Sa Polimorfo de maleato de paroxetina y formulaciones farmaceuticas que lo contienen.
CN1321155A (zh) * 1998-08-07 2001-11-07 史密丝克莱恩比彻姆有限公司 制备非晶性脱水型帕罗西汀盐酸盐的方法
GB9824298D0 (en) * 1998-11-05 1998-12-30 Smithkline Beecham Plc Novel process
GB9826175D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
GB9826176D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
GB9826178D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9826171D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel compounds
GB9826180D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
JP2002531452A (ja) * 1998-11-30 2002-09-24 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 混合パロキセチンプロパン−２−オール溶媒和物
GB9826242D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9828767D0 (en) * 1998-12-29 1999-02-17 Smithkline Beecham Plc Novel process
AU3810100A (en) * 1999-03-12 2000-10-04 Basf Aktiengesellschaft Stable pharmaceutical application form for paroxetin anhydrate
GB9914583D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
GB9914585D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
GB9919001D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel process
GB9923446D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923445D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
HU226912B1 (en) * 2000-04-07 2010-03-01 Richter Gedeon Nyrt New paroxetin salt and medicament containing it
WO2002022609A1 (fr) * 2000-09-14 2002-03-21 Asahi Glass Company, Limited Procede de production de sel de paroxetine sensiblement exempt de solvant organique
IL163593A0 (en) * 2002-02-22 2005-12-18 Teva Pharma Preparation of paroxetine involving novel intermediates
US7563930B2 (en) * 2005-11-22 2009-07-21 Teva Pharmaceutical Industries Ltd Crystal forms of Cinacalcet HCI and processes for their preparation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
GB8430581D0 (en) * 1984-12-04 1985-01-09 Ferrosan As Treatment
EP0223403B1 (en) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidine derivative, its preparation, and its use as medicament
GB8626936D0 (en) * 1986-11-11 1986-12-10 Ferrosan As Treatment
DK716088D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Reduktion af piperidin-dion-derivater samt intermediat
DK715988D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Etherifikation og dealkylering af piperidin-derivater samt intermediater
CA2096853A1 (en) * 1990-11-24 1992-05-25 Anthony Michael Johnson Use of paroxetine for the treatment of senile dementia, bulimia, migraine or anorexia
GB9325644D0 (en) * 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation

Also Published As

Publication number Publication date
CZ297171B6 (cs) 2006-09-13
DE19603797A1 (de) 1996-08-14
CH688353A5 (de) 1997-08-15
KR960031409A (ko) 1996-09-17
NL1002248C2 (nl) 1996-09-11
DK200100223A (es) 2001-02-12
NL1002248A1 (nl) 1996-08-06
DE69631298D1 (de) 2004-02-12
FI20030162A (fi) 2003-02-03
CA2210022A1 (en) 1996-08-07
CA2210023A1 (en) 1996-08-07
SI9600036A (en) 1996-10-31
FI111544B (fi) 2003-08-15
NO301009B3 (es) 2003-01-06
NZ280943A (en) 1997-01-29
PT101827A (pt) 1996-09-30
CA2211522A1 (en) 1996-08-07
HU9600255D0 (en) 1996-03-28
HUP9600255A1 (en) 1997-03-28
EP0808314B1 (en) 2002-06-12
ES2114471B1 (es) 1999-08-16
NO960472L (no) 1996-08-07
CH689229A5 (de) 1998-12-31
FI20030370A (fi) 2003-03-12
PT101827B (pt) 1997-08-29
NO20015070L (no) 1996-08-07
JP2915338B2 (ja) 1999-07-05
SK283608B6 (sk) 2003-10-07
EP1378508A1 (en) 2004-01-07
BR9600534A (pt) 1997-05-13
BG100333A (bg) 1996-08-30
SI9600036B (sl) 2006-12-31
KR100289885B1 (ko) 2001-05-15
PL189247B1 (pl) 2005-07-29
JPH11228571A (ja) 1999-08-24
FI960519A (fi) 1996-08-07
SE9600406L (sv) 1996-08-07
TR199600096A2 (tr) 1996-08-21
AR001982A1 (es) 1998-01-07
AR036856A2 (es) 2004-10-06
CN1143643A (zh) 1997-02-26
FI960519A0 (fi) 1996-02-05
SI21923B (sl) 2006-12-31
ITMI960203A1 (it) 1997-08-05
CN1636993A (zh) 2005-07-13
CA2168829A1 (en) 1996-08-07
NO20015070D0 (no) 2001-10-18
IL117035A0 (en) 1996-09-12
RU2125052C1 (ru) 1999-01-20
SE521084C2 (sv) 2003-09-30
UA49796C2 (uk) 2002-10-15
DE19603797C2 (de) 1998-11-12
FR2730232A1 (fr) 1996-08-09
MY132529A (en) 2007-10-31
MC2411A1 (fr) 1996-12-02
MX198371B (es) 2000-08-29
AU701518C (en) 2006-12-07
LV11618A (lv) 1996-12-20
AU4786496A (en) 1996-08-27
SK14396A3 (en) 1996-11-06
ATA21096A (de) 2000-08-15
CN1216055C (zh) 2005-08-24
SE9600406D0 (sv) 1996-02-05
MA23802A1 (fr) 1996-10-01
DK11996A (da) 1996-08-07
DZ1989A1 (fr) 2002-10-15
AU4332896A (en) 1996-08-15
EP1136490A1 (en) 2001-09-26
IE960104A1 (en) 1996-08-07
AU701518B2 (en) 1999-01-28
NO311519B1 (no) 2001-12-03
DE69621777T2 (de) 2003-01-02
RO112426B1 (ro) 1997-09-30
CA2210022C (en) 2005-09-13
DE69631298T2 (de) 2004-11-18
IT1289532B1 (it) 1998-10-15
CN1310180A (zh) 2001-08-29
LV11618B (en) 1997-04-20
PL312646A1 (en) 1996-08-19
LU88711A1 (fr) 1996-08-23
MX9600484A (es) 1997-01-31
EP0808314A1 (en) 1997-11-26
NO970939D0 (no) 1997-02-28
CZ32096A3 (en) 1996-08-14
HK59397A (en) 1997-05-16
IL117035A (en) 2000-02-29
CN1289496C (zh) 2006-12-13
GR1002466B (el) 1996-11-06
DE69621777D1 (de) 2002-07-18
BE1009112A3 (fr) 1996-11-05
AT407528B (de) 2001-04-25
OA10261A (en) 1997-09-19
IE80500B1 (en) 1998-08-12
NO301009B1 (no) 1997-09-01
NO970939L (no) 1996-08-07
FR2730232B1 (fr) 1997-08-01
SG43787A1 (en) 1997-11-14
CA2168829C (en) 1997-12-16
SI21923A (sl) 2006-06-30
WO1996024595A1 (en) 1996-08-15
ES2114471A1 (es) 1998-05-16
CH689804A5 (de) 1999-11-30
JPH08245620A (ja) 1996-09-24
CN1090187C (zh) 2002-09-04
CA2211522C (en) 1999-12-07
EP1136490B1 (en) 2004-01-07
NO960472D0 (no) 1996-02-05
TW503238B (en) 2002-09-21
ITMI960203A0 (es) 1996-02-05
CA2210023C (en) 1999-02-09

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