ES2028871T3 - Un procedimiento para la preparacion de un glicosido de antraciclina. . - Google Patents

Un procedimiento para la preparacion de un glicosido de antraciclina. .

Info

Publication number
ES2028871T3
ES2028871T3 ES198787306300T ES87306300T ES2028871T3 ES 2028871 T3 ES2028871 T3 ES 2028871T3 ES 198787306300 T ES198787306300 T ES 198787306300T ES 87306300 T ES87306300 T ES 87306300T ES 2028871 T3 ES2028871 T3 ES 2028871T3
Authority
ES
Spain
Prior art keywords
anthracicline
glycoside
procedure
preparation
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787306300T
Other languages
English (en)
Inventor
Francesco Angelucci
Mauro Gigli
Sergio Penco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of ES2028871T3 publication Critical patent/ES2028871T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

GLUCOSIDOS DE ANTRACICLINA DE FORMULA GENERAL (A), DONDE R1 ES HIDROGENO, HIDROXI O METOXI; R2 ES AMINO; R3 ES HIDROGENO O HIDROXI Y X ES HIDROGENO; Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SON AGENTES ANTITUMORALES.
ES198787306300T 1986-07-21 1987-07-16 Un procedimiento para la preparacion de un glicosido de antraciclina. . Expired - Lifetime ES2028871T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868617742A GB8617742D0 (en) 1986-07-21 1986-07-21 6-amino anthracyclines

Publications (1)

Publication Number Publication Date
ES2028871T3 true ES2028871T3 (es) 1992-07-16

Family

ID=10601423

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787306300T Expired - Lifetime ES2028871T3 (es) 1986-07-21 1987-07-16 Un procedimiento para la preparacion de un glicosido de antraciclina. .

Country Status (7)

Country Link
US (1) US4891360A (es)
EP (1) EP0254484B1 (es)
JP (1) JPH07110873B2 (es)
AT (1) ATE63921T1 (es)
DE (1) DE3770359D1 (es)
ES (1) ES2028871T3 (es)
GB (1) GB8617742D0 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2591599B1 (fr) * 1985-12-17 1988-08-05 Hoechst Lab Nouvelles anthracyclines et medicaments les contenant
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
GB8818167D0 (en) * 1988-07-29 1988-09-01 Erba Carlo Spa Novel 4-substituted anthracyclinones & process for their preparation
JP2779652B2 (ja) * 1988-12-27 1998-07-23 武田薬品工業株式会社 生理活性物質ｔａｎ―１１２０，その還元体，それらの製造法および用途ならびに微生物
US5412081A (en) * 1989-02-07 1995-05-02 Farmitalia Carlo Erba S.R.L. New 4'-epi-4'-amino anthracyclines
GB8905668D0 (en) 1989-03-13 1989-04-26 Erba Carlo Spa New 3'-(4-morpholinyl)-and 3'-(2-methoxy-4-morpholinyl)-anthracycline derivatives
GB9019934D0 (en) * 1990-09-12 1990-10-24 Erba Carlo Spa 2-hydroxy-and 2-acyloxy-4-morpholinyl anthracyclines
US5948896A (en) * 1997-08-13 1999-09-07 Gem Pharmaceuticals Processes for preparing 13-deoxy anthracycline derivatives
US5942605A (en) * 1998-03-03 1999-08-24 Gem Pharmaceuticals, Inc. 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4109076A (en) * 1977-09-08 1978-08-22 Sri International 5-iminodaunomycin
US4348388A (en) * 1980-04-02 1982-09-07 G.D. Searle & Co. 11-Amino-11-deoxydaunorubicin and analogs

Also Published As

Publication number Publication date
GB8617742D0 (en) 1986-08-28
JPS6339892A (ja) 1988-02-20
EP0254484A2 (en) 1988-01-27
JPH07110873B2 (ja) 1995-11-29
US4891360A (en) 1990-01-02
ATE63921T1 (de) 1991-06-15
EP0254484B1 (en) 1991-05-29
EP0254484A3 (en) 1988-05-25
DE3770359D1 (de) 1991-07-04

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