DE3770359D1 - 6-amino-anthracycline, verfahren zu ihrer herstellung und ihre verwendung. - Google Patents

6-amino-anthracycline, verfahren zu ihrer herstellung und ihre verwendung.

Info

Publication number
DE3770359D1
DE3770359D1 DE8787306300T DE3770359T DE3770359D1 DE 3770359 D1 DE3770359 D1 DE 3770359D1 DE 8787306300 T DE8787306300 T DE 8787306300T DE 3770359 T DE3770359 T DE 3770359T DE 3770359 D1 DE3770359 D1 DE 3770359D1
Authority
DE
Germany
Prior art keywords
amino
anthracycline
production
hydrogen
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787306300T
Other languages
English (en)
Inventor
Francesco Angelucci
Mauro Gigli
Sergio Penco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of DE3770359D1 publication Critical patent/DE3770359D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE8787306300T 1986-07-21 1987-07-16 6-amino-anthracycline, verfahren zu ihrer herstellung und ihre verwendung. Expired - Fee Related DE3770359D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868617742A GB8617742D0 (en) 1986-07-21 1986-07-21 6-amino anthracyclines

Publications (1)

Publication Number Publication Date
DE3770359D1 true DE3770359D1 (de) 1991-07-04

Family

ID=10601423

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787306300T Expired - Fee Related DE3770359D1 (de) 1986-07-21 1987-07-16 6-amino-anthracycline, verfahren zu ihrer herstellung und ihre verwendung.

Country Status (7)

Country Link
US (1) US4891360A (de)
EP (1) EP0254484B1 (de)
JP (1) JPH07110873B2 (de)
AT (1) ATE63921T1 (de)
DE (1) DE3770359D1 (de)
ES (1) ES2028871T3 (de)
GB (1) GB8617742D0 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2591599B1 (fr) * 1985-12-17 1988-08-05 Hoechst Lab Nouvelles anthracyclines et medicaments les contenant
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
GB8818167D0 (en) * 1988-07-29 1988-09-01 Erba Carlo Spa Novel 4-substituted anthracyclinones & process for their preparation
JP2779652B2 (ja) * 1988-12-27 1998-07-23 武田薬品工業株式会社 生理活性物質ｔａｎ―１１２０，その還元体，それらの製造法および用途ならびに微生物
US5412081A (en) * 1989-02-07 1995-05-02 Farmitalia Carlo Erba S.R.L. New 4'-epi-4'-amino anthracyclines
GB8905668D0 (en) 1989-03-13 1989-04-26 Erba Carlo Spa New 3'-(4-morpholinyl)-and 3'-(2-methoxy-4-morpholinyl)-anthracycline derivatives
GB9019934D0 (en) * 1990-09-12 1990-10-24 Erba Carlo Spa 2-hydroxy-and 2-acyloxy-4-morpholinyl anthracyclines
US5948896A (en) * 1997-08-13 1999-09-07 Gem Pharmaceuticals Processes for preparing 13-deoxy anthracycline derivatives
US5942605A (en) * 1998-03-03 1999-08-24 Gem Pharmaceuticals, Inc. 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4109076A (en) * 1977-09-08 1978-08-22 Sri International 5-iminodaunomycin
US4348388A (en) * 1980-04-02 1982-09-07 G.D. Searle & Co. 11-Amino-11-deoxydaunorubicin and analogs

Also Published As

Publication number Publication date
EP0254484B1 (de) 1991-05-29
EP0254484A2 (de) 1988-01-27
EP0254484A3 (en) 1988-05-25
JPH07110873B2 (ja) 1995-11-29
GB8617742D0 (en) 1986-08-28
US4891360A (en) 1990-01-02
ATE63921T1 (de) 1991-06-15
ES2028871T3 (es) 1992-07-16
JPS6339892A (ja) 1988-02-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee