MX8481A - Procedimiento para preparar compuestos de carboestirilo. - Google Patents

Procedimiento para preparar compuestos de carboestirilo.

Info

Publication number
MX8481A
MX8481A MX848185A MX848185A MX8481A MX 8481 A MX8481 A MX 8481A MX 848185 A MX848185 A MX 848185A MX 848185 A MX848185 A MX 848185A MX 8481 A MX8481 A MX 8481A
Authority
MX
Mexico
Prior art keywords
carboestyral
preparing
compounds
procedure
preparing carboestyral
Prior art date
Application number
MX848185A
Other languages
English (en)
Inventor
Michiaki Tominaga
Original Assignee
Otsuka Pharmaceutical Col Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Col Ltd filed Critical Otsuka Pharmaceutical Col Ltd
Publication of MX8481A publication Critical patent/MX8481A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/40—Nitrogen atoms attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
MX848185A 1980-10-31 1985-08-09 Procedimiento para preparar compuestos de carboestirilo. MX8481A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55154071A JPS5777676A (en) 1980-10-31 1980-10-31 Carbostyril derivative

Publications (1)

Publication Number Publication Date
MX8481A true MX8481A (es) 1994-02-28

Family

ID=15576252

Family Applications (1)

Application Number Title Priority Date Filing Date
MX848185A MX8481A (es) 1980-10-31 1985-08-09 Procedimiento para preparar compuestos de carboestirilo.

Country Status (24)

Country Link
US (1) US4415572A (es)
JP (1) JPS5777676A (es)
KR (1) KR860001944B1 (es)
AR (2) AR242563A1 (es)
AT (1) AT381701B (es)
AU (1) AU524419B2 (es)
BE (1) BE890942A (es)
CA (1) CA1209575A (es)
CH (2) CH650782A5 (es)
DE (2) DE3153260C2 (es)
DK (1) DK155665C (es)
ES (3) ES8306743A1 (es)
FI (1) FI77450C (es)
FR (2) FR2493320B1 (es)
GB (1) GB2086896B (es)
IT (2) IT1210585B (es)
MX (1) MX8481A (es)
NL (2) NL194205C (es)
NO (1) NO158099C (es)
PH (1) PH17962A (es)
PT (1) PT73910B (es)
SE (2) SE448877B (es)
SU (1) SU1426452A3 (es)
ZA (1) ZA817515B (es)

Families Citing this family (63)

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JPS5883677A (ja) * 1981-11-11 1983-05-19 Otsuka Pharmaceut Co Ltd カルボスチリル誘導体
JPS5929667A (ja) * 1982-08-13 1984-02-16 Otsuka Pharmaceut Co Ltd カルボスチリル誘導体および強心剤
CH655110A5 (de) * 1982-09-03 1986-03-27 Otsuka Pharma Co Ltd Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten.
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
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JPS60126270A (ja) * 1983-12-14 1985-07-05 Otsuka Pharmaceut Co Ltd カルボスチリル誘導体
US4710507A (en) * 1983-12-22 1987-12-01 Pfizer Inc. Quinolone inotropic agents
US4774246A (en) * 1984-01-26 1988-09-27 Abbott Laboratories Quinoline antibacterial compounds
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JPS61145162A (ja) * 1984-12-19 1986-07-02 Otsuka Pharmaceut Co Ltd カルボスチリル誘導体
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US5358949A (en) * 1986-03-05 1994-10-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives
GB8630702D0 (en) * 1986-12-23 1987-02-04 Wellcome Found Quinoline compound
US5166160A (en) * 1986-12-23 1992-11-24 Burroughs Wellcome Co. Quinoline compound
JPS63225357A (ja) * 1987-03-12 1988-09-20 Otsuka Pharmaceut Co Ltd カルボスチリル誘導体
GB8827189D0 (en) * 1988-11-21 1988-12-29 Fujisawa Pharmaceutical Co 2(1h)-quinolinone compounds processes for preparation thereof & pharmaceutical composition comprising same
US5750529A (en) * 1991-07-03 1998-05-12 Otsuka Pharmaceutical Co., Ltd. Apoptosis regulating compostion
AU648690B2 (en) * 1991-07-03 1994-04-28 Otsuka Pharmaceutical Co., Ltd. Apoptosis regulator
JP2597953B2 (ja) * 1991-12-10 1997-04-09 大塚製薬株式会社 制癌剤
JP2686887B2 (ja) * 1992-08-11 1997-12-08 キッセイ薬品工業株式会社 ピペリジノ−３，４−ジヒドロカルボスチリル誘導体
AU666577B2 (en) * 1992-08-19 1996-02-15 Otsuka Pharmaceutical Co., Ltd. Apoptosis regulator
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CA2134880A1 (en) * 1993-03-02 1994-09-03 Akira Matsumori Graft rejection inhibitor and il-1 production inhibitor
JPH0733664A (ja) * 1993-07-26 1995-02-03 Otsuka Pharmaceut Co Ltd 平滑筋細胞増殖抑制剤
GB9326373D0 (en) * 1993-12-23 1994-02-23 Zeneca Ltd Chemical compounds
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US5504093A (en) * 1994-08-01 1996-04-02 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting nucleoside and nucleobase transport in mammalian cells, and method for inhibition of DNA virus replication
PL189256B1 (pl) * 1996-03-29 2005-07-29 Duphar Int Res Związki piperazyny i piperydyny, sposób ich wytwarzania, kompozycja farmaceutyczna zawierająca te związki, zastosowanie tych związków do wytwarzania leków
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JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
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JP2022533251A (ja) 2019-05-21 2022-07-21 アルデリックス， インコーポレイテッド 患者において血清リン酸塩を低下させるための組み合わせ

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JPS6017072B2 (ja) * 1978-09-05 1985-04-30 三菱電機株式会社 赤熱金属検出器
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Also Published As

Publication number Publication date
DK480381A (da) 1982-05-01
NL194205B (nl) 2001-05-01
NL8403096A (nl) 1985-02-01
PH17962A (en) 1985-02-20
JPH0143747B2 (es) 1989-09-22
SU1426452A3 (ru) 1988-09-23
CH656616A5 (de) 1986-07-15
AU524419B2 (en) 1982-09-16
BE890942A (fr) 1982-02-15
NL8104923A (nl) 1982-05-17
AR242563A1 (es) 1993-04-30
ES520637A0 (es) 1984-04-16
KR860001944B1 (ko) 1986-11-01
AR242375A1 (es) 1993-03-31
IT1210585B (it) 1989-09-14
KR830007607A (ko) 1983-11-04
ZA817515B (en) 1982-10-27
SE466655B (sv) 1992-03-16
ES507198A0 (es) 1983-06-16
PT73910A (en) 1981-11-01
NL194205C (nl) 2001-09-04
CA1209575A (en) 1986-08-12
FI77450C (fi) 1989-03-10
FR2493320B1 (fr) 1985-08-23
IT8547867A0 (it) 1985-03-26
FI813408L (fi) 1982-05-01
GB2086896A (en) 1982-05-19
ES8403886A1 (es) 1984-04-16
ES8306743A1 (es) 1983-06-16
SE8106430L (sv) 1982-05-01
DE3153260C2 (es) 1989-05-24
FI77450B (fi) 1988-11-30
ATA460281A (de) 1986-04-15
ES8403885A1 (es) 1984-04-16
NO813678L (no) 1982-05-03
US4415572A (en) 1983-11-15
IT1226479B (it) 1991-01-16
ES520638A0 (es) 1984-04-16
NO158099B (no) 1988-04-05
DE3142982C2 (de) 1985-12-19
DK155665C (da) 1989-09-04
CH650782A5 (de) 1985-08-15
DE3142982A1 (de) 1982-06-24
JPS5777676A (en) 1982-05-15
SE8406209D0 (sv) 1984-12-06
SE8406209L (sv) 1984-12-06
SE448877B (sv) 1987-03-23
DK155665B (da) 1989-05-01
PT73910B (en) 1983-04-18
AU7699681A (en) 1982-05-06
FR2493320A1 (fr) 1982-05-07
GB2086896B (en) 1984-10-10
FR2552760A1 (fr) 1985-04-05
DE3153260A1 (es) 1985-05-15
NO158099C (no) 1988-07-13
AT381701B (de) 1986-11-25
FR2552760B1 (fr) 1988-08-05
IT8149588A0 (it) 1981-10-29

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