ES523064A0 - Procedimiento para preparar azetidinas. - Google Patents

Procedimiento para preparar azetidinas.

Info

Publication number
ES523064A0
ES523064A0 ES523064A ES523064A ES523064A0 ES 523064 A0 ES523064 A0 ES 523064A0 ES 523064 A ES523064 A ES 523064A ES 523064 A ES523064 A ES 523064A ES 523064 A0 ES523064 A0 ES 523064A0
Authority
ES
Spain
Prior art keywords
azetidins
preparing
procedure
preparing azetidins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES523064A
Other languages
English (en)
Other versions
ES8502969A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ES8502969A1 publication Critical patent/ES8502969A1/es
Publication of ES523064A0 publication Critical patent/ES523064A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/683Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES523064A 1982-02-09 1983-06-07 Procedimiento para preparar azetidinas. Granted ES523064A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34712382A 1982-02-09 1982-02-09
US06/408,333 US4540690A (en) 1982-02-09 1982-08-16 2-(Phenylmethylene)cycloalkylamines and -azetidines

Publications (2)

Publication Number Publication Date
ES8502969A1 ES8502969A1 (es) 1984-10-01
ES523064A0 true ES523064A0 (es) 1984-10-01

Family

ID=26995138

Family Applications (6)

Application Number Title Priority Date Filing Date
ES519331A Expired ES8501744A1 (es) 1982-02-09 1983-01-28 Procedimiento para preparar un compuesto de 2-(fenilmetilen) cicloalquilaminas y -azetidinas.
ES523064A Granted ES523064A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar azetidinas.
ES523065A Granted ES523065A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar compuestos de n-(2-(fenilmetilen)cicloalquil) aminas libres. desglose de la patente n 519.331.
ES523067A Granted ES523067A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar 1-(2-(fenilmetilen)ciclohexil) azetidinas.
ES523066A Granted ES523066A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar compuestos de azetidinas. desglose de la patente n 519.331.
ES532058A Expired ES8507483A1 (es) 1982-02-09 1984-04-30 Procedimiento para preparar un compuesto de 2-(fenilmetilen) cicloalquilaminas y azetidinas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES519331A Expired ES8501744A1 (es) 1982-02-09 1983-01-28 Procedimiento para preparar un compuesto de 2-(fenilmetilen) cicloalquilaminas y -azetidinas.

Family Applications After (4)

Application Number Title Priority Date Filing Date
ES523065A Granted ES523065A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar compuestos de n-(2-(fenilmetilen)cicloalquil) aminas libres. desglose de la patente n 519.331.
ES523067A Granted ES523067A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar 1-(2-(fenilmetilen)ciclohexil) azetidinas.
ES523066A Granted ES523066A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar compuestos de azetidinas. desglose de la patente n 519.331.
ES532058A Expired ES8507483A1 (es) 1982-02-09 1984-04-30 Procedimiento para preparar un compuesto de 2-(fenilmetilen) cicloalquilaminas y azetidinas

Country Status (11)

Country Link
US (1) US4540690A (es)
EP (1) EP0085811B1 (es)
AU (2) AU562051B2 (es)
DE (1) DE3271073D1 (es)
DK (1) DK53083A (es)
ES (6) ES8501744A1 (es)
GR (1) GR78061B (es)
HU (1) HU190887B (es)
IL (1) IL67442A (es)
NZ (1) NZ202728A (es)
PH (1) PH17709A (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2634483B2 (fr) * 1987-12-29 1994-03-04 Esteve Labor Dr Derives des acides 7-(1-azetidinyl)-1,4-dihydro-4-oxoquinoleine-3-carboxyliques, leur preparation et leur application en tant que medicaments
JP3739377B2 (ja) * 2003-12-10 2006-01-25 シャープ株式会社 洗濯乾燥機
PL380887A1 (pl) * 2003-12-29 2007-04-02 Sepracor Inc. Pirolowe i pirazolowe inhibitory DAAO
EP1904066B1 (en) 2005-07-06 2018-05-23 Sunovion Pharmaceuticals Inc. COMBINATIONS OF ESZOPICLONE AND TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE OR TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPTHALENAMINE, for treating MENOPAUSE, perimenopause AND COGNITIVE DISORDERS
US20070203111A1 (en) 2006-01-06 2007-08-30 Sepracor Inc. Cycloalkylamines as monoamine reuptake inhibitors
CN104276955A (zh) * 2006-01-06 2015-01-14 赛诺维信制药公司 基于四氢萘酮的单胺再摄取抑制剂
ES2555315T3 (es) 2006-03-31 2015-12-30 Sunovion Pharmaceuticals Inc. Preparación de amidas y aminas quirales
US7579370B2 (en) * 2006-06-30 2009-08-25 Sepracor Inc. Fused heterocycles
US7884124B2 (en) 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US20080082066A1 (en) * 2006-10-02 2008-04-03 Weyerhaeuser Co. Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks
CA2676432A1 (en) * 2007-01-18 2008-07-24 Sepracor, Inc. Inhibitors of d-amino acid oxidase
US7902252B2 (en) * 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
MX2009012685A (es) 2007-05-31 2009-12-14 Sepracor Inc Cicloalquilaminas sustituidas con fenilo como inhibidores de la reabsorcion de monoamina.
WO2010017418A1 (en) * 2008-08-07 2010-02-11 Sepracor Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
WO2011017634A2 (en) * 2009-08-07 2011-02-10 Sepracore Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
EP2758375A1 (en) * 2011-09-23 2014-07-30 Advinus Therapeutics Limited Amide compounds, compositions and applications thereof
JP6588475B2 (ja) * 2014-06-06 2019-10-09 アラーガン、インコーポレイテッドAllergan,Incorporated 治療用化合物としての新規のep4アゴニスト
KR102270026B1 (ko) * 2020-01-31 2021-06-28 현대약품 주식회사 (3s)-3-(4-(3-(1,4-다이옥사스파이로[4,5]데스-7-엔-8-일)벤질옥시)페닐)헥스-4-이노익산의 품질 평가 방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558599A (en) * 1966-06-13 1971-01-26 Upjohn Co 1-(2-(alpha-alkoxybenzyl and substituted benzyl)cycloalkyl)heterocyclic amines
US3632813A (en) * 1966-06-13 1972-01-04 Upjohn Co Substituted phenyl 2-piperidinocycloalkyl ketones
US3705176A (en) * 1966-06-13 1972-12-05 Upjohn Co 1,3-aminoalcohols
US3668199A (en) * 1966-06-13 1972-06-06 Upjohn Co 1,3-aminoalcohols
US3595867A (en) * 1966-06-13 1971-07-27 Upjohn Co 2 - piperidino- and methyl-substituted piperidino-substituted-phentl cycloalkane-methanols and derivatives
US3468881A (en) * 1966-08-15 1969-09-23 Upjohn Co Allylic amines
US3458523A (en) * 1966-08-15 1969-07-29 Upjohn Co 2-(2 - furoyl)cycloalkanones,2 - furyl-2-(heterocyclicamino) cycloalkyl ketones,and d-(2 - furyl)-2-heterocyclicamino-cyclohexanemethanols
US3506670A (en) * 1966-09-26 1970-04-14 Upjohn Co 2-hetero-amino-alpha,alpha-diaryl-cycloalkone-methanols and esters thereof
US3499033A (en) * 1967-01-06 1970-03-03 Upjohn Co Ethers of alpha-phenyl-2-aminocycloalkanemethanols
US3651232A (en) * 1968-09-10 1972-03-21 Upjohn Co Compositions and methods for lowering blood sugar levels
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds
US4098904A (en) * 1976-11-12 1978-07-04 The Upjohn Company Analgesic n-(2-aminocycloaliphatic)benzamides
US4242261A (en) * 1979-07-19 1980-12-30 A. H. Robins Company, Inc. Production of methylene-cycloamines
US4260606A (en) * 1979-07-19 1981-04-07 A. H. Robins Company, Inc. 3-Methyleneazetidine derivatives

Also Published As

Publication number Publication date
IL67442A0 (en) 1983-05-15
ES519331A0 (es) 1984-12-16
ES8501746A1 (es) 1984-12-16
ES8502969A1 (es) 1984-10-01
ES8502673A1 (es) 1985-02-01
HU190887B (en) 1986-12-28
DK53083D0 (da) 1983-02-08
ES523065A0 (es) 1985-02-01
EP0085811A1 (en) 1983-08-17
DE3271073D1 (de) 1986-06-12
AU9134382A (en) 1983-08-18
GR78061B (es) 1984-09-26
DK53083A (da) 1983-08-10
ES532058A0 (es) 1985-09-16
EP0085811B1 (en) 1986-05-07
AU6350486A (en) 1987-01-15
US4540690A (en) 1985-09-10
ES8501744A1 (es) 1984-12-16
AU562051B2 (en) 1987-05-28
ES8501745A1 (es) 1984-12-16
NZ202728A (en) 1985-12-13
ES523067A0 (es) 1984-12-16
ES8507483A1 (es) 1985-09-16
IL67442A (en) 1986-01-31
PH17709A (en) 1984-11-19
ES523066A0 (es) 1984-12-16

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