DK53083A - Fremgangsmaade til fremstilling af 2-(phenyl-methylen)-cycloalkylaminer og -azetidiner eller syreadditionssalte deraf - Google Patents
Fremgangsmaade til fremstilling af 2-(phenyl-methylen)-cycloalkylaminer og -azetidiner eller syreadditionssalte deraf Download PDFInfo
- Publication number
- DK53083A DK53083A DK53083A DK53083A DK53083A DK 53083 A DK53083 A DK 53083A DK 53083 A DK53083 A DK 53083A DK 53083 A DK53083 A DK 53083A DK 53083 A DK53083 A DK 53083A
- Authority
- DK
- Denmark
- Prior art keywords
- zetididin
- cylamines
- cycloal
- methylene
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
- C07C45/66—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
- C07C49/683—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34712382A | 1982-02-09 | 1982-02-09 | |
US06/408,333 US4540690A (en) | 1982-02-09 | 1982-08-16 | 2-(Phenylmethylene)cycloalkylamines and -azetidines |
Publications (2)
Publication Number | Publication Date |
---|---|
DK53083D0 DK53083D0 (da) | 1983-02-08 |
DK53083A true DK53083A (da) | 1983-08-10 |
Family
ID=26995138
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK53083A DK53083A (da) | 1982-02-09 | 1983-02-08 | Fremgangsmaade til fremstilling af 2-(phenyl-methylen)-cycloalkylaminer og -azetidiner eller syreadditionssalte deraf |
Country Status (11)
Country | Link |
---|---|
US (1) | US4540690A (da) |
EP (1) | EP0085811B1 (da) |
AU (2) | AU562051B2 (da) |
DE (1) | DE3271073D1 (da) |
DK (1) | DK53083A (da) |
ES (6) | ES8501744A1 (da) |
GR (1) | GR78061B (da) |
HU (1) | HU190887B (da) |
IL (1) | IL67442A (da) |
NZ (1) | NZ202728A (da) |
PH (1) | PH17709A (da) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2634483B2 (fr) * | 1987-12-29 | 1994-03-04 | Esteve Labor Dr | Derives des acides 7-(1-azetidinyl)-1,4-dihydro-4-oxoquinoleine-3-carboxyliques, leur preparation et leur application en tant que medicaments |
JP3739377B2 (ja) * | 2003-12-10 | 2006-01-25 | シャープ株式会社 | 洗濯乾燥機 |
US7488747B2 (en) * | 2003-12-29 | 2009-02-10 | Sepracor Inc. | Pyrrole and pyrazole DAAO inhibitors |
CA2957667A1 (en) | 2005-07-06 | 2007-01-11 | Sepracor Inc. | Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders |
WO2007081542A2 (en) * | 2006-01-06 | 2007-07-19 | Sepracor Inc. | Tetralone-based monoamine reuptake inhibitors |
ES2594156T3 (es) | 2006-01-06 | 2016-12-16 | Sunovion Pharmaceuticals Inc. | Cicloalquilaminas como inhibidores de la recaptación de monoaminas |
ES2555315T3 (es) | 2006-03-31 | 2015-12-30 | Sunovion Pharmaceuticals Inc. | Preparación de amidas y aminas quirales |
US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
US7579370B2 (en) * | 2006-06-30 | 2009-08-25 | Sepracor Inc. | Fused heterocycles |
US20080082066A1 (en) * | 2006-10-02 | 2008-04-03 | Weyerhaeuser Co. | Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks |
US7902252B2 (en) * | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
BRPI0806604A2 (pt) * | 2007-01-18 | 2011-09-06 | Sepracor Inc | inibidores de d-aminoácido oxidase |
AU2008259841B2 (en) * | 2007-05-31 | 2015-02-05 | Sunovion Pharmaceuticals Inc. | Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors |
US20100120740A1 (en) * | 2008-08-07 | 2010-05-13 | Sepracor Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
US20110034434A1 (en) * | 2009-08-07 | 2011-02-10 | Sepracor Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
CA2849726A1 (en) * | 2011-09-23 | 2013-03-28 | Advinus Therapeutics Limited | Amide compounds, compositions and applications thereof |
JP6588475B2 (ja) * | 2014-06-06 | 2019-10-09 | アラーガン、インコーポレイテッドAllergan,Incorporated | 治療用化合物としての新規のep4アゴニスト |
KR102270026B1 (ko) * | 2020-01-31 | 2021-06-28 | 현대약품 주식회사 | (3s)-3-(4-(3-(1,4-다이옥사스파이로[4,5]데스-7-엔-8-일)벤질옥시)페닐)헥스-4-이노익산의 품질 평가 방법 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3705176A (en) * | 1966-06-13 | 1972-12-05 | Upjohn Co | 1,3-aminoalcohols |
US3558599A (en) * | 1966-06-13 | 1971-01-26 | Upjohn Co | 1-(2-(alpha-alkoxybenzyl and substituted benzyl)cycloalkyl)heterocyclic amines |
US3632813A (en) * | 1966-06-13 | 1972-01-04 | Upjohn Co | Substituted phenyl 2-piperidinocycloalkyl ketones |
US3668199A (en) * | 1966-06-13 | 1972-06-06 | Upjohn Co | 1,3-aminoalcohols |
US3595867A (en) * | 1966-06-13 | 1971-07-27 | Upjohn Co | 2 - piperidino- and methyl-substituted piperidino-substituted-phentl cycloalkane-methanols and derivatives |
US3458523A (en) * | 1966-08-15 | 1969-07-29 | Upjohn Co | 2-(2 - furoyl)cycloalkanones,2 - furyl-2-(heterocyclicamino) cycloalkyl ketones,and d-(2 - furyl)-2-heterocyclicamino-cyclohexanemethanols |
US3468881A (en) * | 1966-08-15 | 1969-09-23 | Upjohn Co | Allylic amines |
US3506670A (en) * | 1966-09-26 | 1970-04-14 | Upjohn Co | 2-hetero-amino-alpha,alpha-diaryl-cycloalkone-methanols and esters thereof |
US3499033A (en) * | 1967-01-06 | 1970-03-03 | Upjohn Co | Ethers of alpha-phenyl-2-aminocycloalkanemethanols |
US3651232A (en) * | 1968-09-10 | 1972-03-21 | Upjohn Co | Compositions and methods for lowering blood sugar levels |
US4098904A (en) * | 1976-11-12 | 1978-07-04 | The Upjohn Company | Analgesic n-(2-aminocycloaliphatic)benzamides |
US4145435A (en) * | 1976-11-12 | 1979-03-20 | The Upjohn Company | 2-aminocycloaliphatic amide compounds |
US4242261A (en) * | 1979-07-19 | 1980-12-30 | A. H. Robins Company, Inc. | Production of methylene-cycloamines |
US4260606A (en) * | 1979-07-19 | 1981-04-07 | A. H. Robins Company, Inc. | 3-Methyleneazetidine derivatives |
-
1982
- 1982-08-16 US US06/408,333 patent/US4540690A/en not_active Expired - Fee Related
- 1982-12-07 NZ NZ202728A patent/NZ202728A/en unknown
- 1982-12-08 AU AU91343/82A patent/AU562051B2/en not_active Expired - Fee Related
- 1982-12-09 IL IL67442A patent/IL67442A/xx unknown
- 1982-12-20 EP EP82306779A patent/EP0085811B1/en not_active Expired
- 1982-12-20 DE DE8282306779T patent/DE3271073D1/de not_active Expired
-
1983
- 1983-01-03 PH PH28337A patent/PH17709A/en unknown
- 1983-01-28 ES ES519331A patent/ES8501744A1/es not_active Expired
- 1983-02-04 GR GR70420A patent/GR78061B/el unknown
- 1983-02-08 DK DK53083A patent/DK53083A/da not_active Application Discontinuation
- 1983-02-08 HU HU83432A patent/HU190887B/hu unknown
- 1983-06-07 ES ES523065A patent/ES8502673A1/es not_active Expired
- 1983-06-07 ES ES523067A patent/ES523067A0/es active Granted
- 1983-06-07 ES ES523066A patent/ES8501745A1/es not_active Expired
- 1983-06-07 ES ES523064A patent/ES523064A0/es active Granted
-
1984
- 1984-04-30 ES ES532058A patent/ES532058A0/es active Granted
-
1986
- 1986-10-03 AU AU63504/86A patent/AU6350486A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU6350486A (en) | 1987-01-15 |
IL67442A (en) | 1986-01-31 |
NZ202728A (en) | 1985-12-13 |
PH17709A (en) | 1984-11-19 |
ES523066A0 (es) | 1984-12-16 |
ES8501746A1 (es) | 1984-12-16 |
US4540690A (en) | 1985-09-10 |
EP0085811A1 (en) | 1983-08-17 |
AU9134382A (en) | 1983-08-18 |
ES8502969A1 (es) | 1984-10-01 |
EP0085811B1 (en) | 1986-05-07 |
ES523064A0 (es) | 1984-10-01 |
ES523067A0 (es) | 1984-12-16 |
ES8507483A1 (es) | 1985-09-16 |
AU562051B2 (en) | 1987-05-28 |
IL67442A0 (en) | 1983-05-15 |
ES8501745A1 (es) | 1984-12-16 |
ES523065A0 (es) | 1985-02-01 |
GR78061B (da) | 1984-09-26 |
ES519331A0 (es) | 1984-12-16 |
ES532058A0 (es) | 1985-09-16 |
ES8502673A1 (es) | 1985-02-01 |
HU190887B (en) | 1986-12-28 |
DE3271073D1 (de) | 1986-06-12 |
DK53083D0 (da) | 1983-02-08 |
ES8501744A1 (es) | 1984-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ATS | Application withdrawn |