JPS5583781A - Pyridazinone derivative - Google Patents
Pyridazinone derivativeInfo
- Publication number
- JPS5583781A JPS5583781A JP15807978A JP15807978A JPS5583781A JP S5583781 A JPS5583781 A JP S5583781A JP 15807978 A JP15807978 A JP 15807978A JP 15807978 A JP15807978 A JP 15807978A JP S5583781 A JPS5583781 A JP S5583781A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- reacted
- give
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
NEW MATERIAL:A pyridazinone derivative of formula I: (R1 and R2 are lower alkyl groups, or may form a heterocyclic ring together with the adjacent N atom; R3 and R4 are H or lower alkyl groups; n is 2 or 3).
EXAMPLE: 1-( 2-Diethylaminoethyl )-4,4-dimethyl-6-(5-methyl-3-oxo-2,3,4,5-tetrahydropyridazin-6-yl)-1,2,3,4-tetrahydroquinolin-2-one hydrochloride-hemihydrate.
USE: Antithrombotics, antidepressive agents, and intermediates for their synthesis.
PROCESS: A compound of formula III is reacted with a compound of formula IV: (X is halogen) to give a compound of formula V, which is hydrolyzed to form a compound of formula II. The resulting compound or its reactive derivative is then reacted with hydrazine or its hydrate to give the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15807978A JPS5583781A (en) | 1978-12-19 | 1978-12-19 | Pyridazinone derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15807978A JPS5583781A (en) | 1978-12-19 | 1978-12-19 | Pyridazinone derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5583781A true JPS5583781A (en) | 1980-06-24 |
JPS6257628B2 JPS6257628B2 (en) | 1987-12-02 |
Family
ID=15663828
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15807978A Granted JPS5583781A (en) | 1978-12-19 | 1978-12-19 | Pyridazinone derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5583781A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4415572A (en) * | 1980-10-31 | 1983-11-15 | Otsuka Pharmaceutical Co., Ltd. | Piperazinylcarbostyril compounds |
US5656633A (en) * | 1991-05-08 | 1997-08-12 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and pharmaceutical compositions containing the same for use as a disturbance-of-consciousness improving agent, central nervous system stimulant or sigma receptor agonist |
-
1978
- 1978-12-19 JP JP15807978A patent/JPS5583781A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4415572A (en) * | 1980-10-31 | 1983-11-15 | Otsuka Pharmaceutical Co., Ltd. | Piperazinylcarbostyril compounds |
US5656633A (en) * | 1991-05-08 | 1997-08-12 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and pharmaceutical compositions containing the same for use as a disturbance-of-consciousness improving agent, central nervous system stimulant or sigma receptor agonist |
Also Published As
Publication number | Publication date |
---|---|
JPS6257628B2 (en) | 1987-12-02 |
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