JPS5515457A - Dithiocarbamic acid derivative - Google Patents

Dithiocarbamic acid derivative

Info

Publication number
JPS5515457A
JPS5515457A JP8915378A JP8915378A JPS5515457A JP S5515457 A JPS5515457 A JP S5515457A JP 8915378 A JP8915378 A JP 8915378A JP 8915378 A JP8915378 A JP 8915378A JP S5515457 A JPS5515457 A JP S5515457A
Authority
JP
Japan
Prior art keywords
compound
acid derivative
lower alkyl
dithiocarbamic acid
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8915378A
Other languages
Japanese (ja)
Inventor
Hiroshi Yuki
Kazuyuki Kawasaki
Yutaka Maruyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP8915378A priority Critical patent/JPS5515457A/en
Publication of JPS5515457A publication Critical patent/JPS5515457A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:A dithiocarbamic acid derivative of formula I (R1, R2 are lower alkyl, aralkyl; R1 and R2 may together with the adjacent N atom form a heterocylic ring; R3 is H, lower alkyl; A, B are straight or branched chain alkylene; X is methylene, S), its acid addition salt, and their stereoisomers.
EXAMPLE: 3-[3-( 2-Dimethylaminoethylthiocarbamoylthio )-2(S)-methylpropionyl]- 4(R)-thiazolidinecarboxylic acid.
USE: Drug having anti-inflammatory, anti-rheumatic, hypotensive, immuno-regulating, and carcinostatic activities.
PROCESS: The compound I is prepared by reacting a compound II with a compound III in an inert solvent, in the absence or presence of catalsyt such as tertiary amine, at a temperature between the room temperature and about 150°C.
COPYRIGHT: (C)1980,JPO&Japio
JP8915378A 1978-07-20 1978-07-20 Dithiocarbamic acid derivative Pending JPS5515457A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8915378A JPS5515457A (en) 1978-07-20 1978-07-20 Dithiocarbamic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8915378A JPS5515457A (en) 1978-07-20 1978-07-20 Dithiocarbamic acid derivative

Publications (1)

Publication Number Publication Date
JPS5515457A true JPS5515457A (en) 1980-02-02

Family

ID=13962897

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8915378A Pending JPS5515457A (en) 1978-07-20 1978-07-20 Dithiocarbamic acid derivative

Country Status (1)

Country Link
JP (1) JPS5515457A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0049842A2 (en) * 1980-10-06 1982-04-21 Merck & Co. Inc. Substituted enantholactam derivatives, a process for the preparation and a pharmaceutical composition useful in the treatment of hypertension comprising the same, and intermediates
WO1998043954A1 (en) * 1997-03-27 1998-10-08 Santen Pharmaceutical Co., Ltd. Leukotriene a4 hydrolaze inhibitors
US6747061B2 (en) 2000-03-21 2004-06-08 Atherogenics, Inc. N-substituted dithiocarbamates for the treatment of biological disorders

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0049842A2 (en) * 1980-10-06 1982-04-21 Merck & Co. Inc. Substituted enantholactam derivatives, a process for the preparation and a pharmaceutical composition useful in the treatment of hypertension comprising the same, and intermediates
WO1998043954A1 (en) * 1997-03-27 1998-10-08 Santen Pharmaceutical Co., Ltd. Leukotriene a4 hydrolaze inhibitors
US6242476B1 (en) 1997-03-27 2001-06-05 Santen Pharmaceutical Co., Ltd. Leukotriene A4 hydrolase inhibitors
US6747061B2 (en) 2000-03-21 2004-06-08 Atherogenics, Inc. N-substituted dithiocarbamates for the treatment of biological disorders

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