JPS57149277A - Heterocyclic compound - Google Patents
Heterocyclic compoundInfo
- Publication number
- JPS57149277A JPS57149277A JP3489681A JP3489681A JPS57149277A JP S57149277 A JPS57149277 A JP S57149277A JP 3489681 A JP3489681 A JP 3489681A JP 3489681 A JP3489681 A JP 3489681A JP S57149277 A JPS57149277 A JP S57149277A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- formulai
- lower alkyl
- reacted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formulaI(R1 and R3 are H, lower alkyl, aralkyl, phenyl, etc.; R2 is H or lower alkyl or R2 and R3 together with N may form a heterocyclic ring; Z is H, lower alkyl or lower alkoxyl; n is 0 is 1; X is O or S).
EXAMPLE: 1-Methylcarbamoyl-2-benzimidazolinone.
USE: An anti-inflammatory and analgesic agent.
PROCESS: A compound of formula II is reacted with a compound of formula III at -20°C... the reflux temperature of a solvent to give the compound of formulaI (R2 is H). Alternatively, the compound of formula II is reacted with a dialkylcarbamoyl halide of formula IV (R4 and R5 are lower alkyl) to afford the compound of formulaI(X is O). The compound of formula II is reacted with a compound of formula V to give the compound of formulaI(X is O; R2 and R3 together with N form an imidazolyl group).
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3489681A JPS57149277A (en) | 1981-03-10 | 1981-03-10 | Heterocyclic compound |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3489681A JPS57149277A (en) | 1981-03-10 | 1981-03-10 | Heterocyclic compound |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57149277A true JPS57149277A (en) | 1982-09-14 |
JPS646193B2 JPS646193B2 (en) | 1989-02-02 |
Family
ID=12426932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3489681A Granted JPS57149277A (en) | 1981-03-10 | 1981-03-10 | Heterocyclic compound |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57149277A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996039404A1 (en) * | 1995-06-05 | 1996-12-12 | Neurogen Corporation | Novel substituted aryl and cycloalkyl imidazolones; a new class of gaba brain receptor ligands |
WO2001042224A1 (en) * | 1999-12-09 | 2001-06-14 | Mitsubishi Pharma Corporation | Carboxyamido derivatives |
CN100432059C (en) * | 2002-10-11 | 2008-11-12 | 诺瓦提斯公司 | Quinazolinone derivatives useful as anti-hyperalgesic agents |
-
1981
- 1981-03-10 JP JP3489681A patent/JPS57149277A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996039404A1 (en) * | 1995-06-05 | 1996-12-12 | Neurogen Corporation | Novel substituted aryl and cycloalkyl imidazolones; a new class of gaba brain receptor ligands |
WO2001042224A1 (en) * | 1999-12-09 | 2001-06-14 | Mitsubishi Pharma Corporation | Carboxyamido derivatives |
CN100432059C (en) * | 2002-10-11 | 2008-11-12 | 诺瓦提斯公司 | Quinazolinone derivatives useful as anti-hyperalgesic agents |
Also Published As
Publication number | Publication date |
---|---|
JPS646193B2 (en) | 1989-02-02 |
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