JPS55104274A - Isoxazolin-3-one derivative and its preparation - Google Patents

Isoxazolin-3-one derivative and its preparation

Info

Publication number
JPS55104274A
JPS55104274A JP1203979A JP1203979A JPS55104274A JP S55104274 A JPS55104274 A JP S55104274A JP 1203979 A JP1203979 A JP 1203979A JP 1203979 A JP1203979 A JP 1203979A JP S55104274 A JPS55104274 A JP S55104274A
Authority
JP
Japan
Prior art keywords
formula
isoxazolin
halogen
compound
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1203979A
Other languages
Japanese (ja)
Inventor
Norio Nakamura
Mitsuo Nagano
Junichi Sakai
Hidekazu Mitsusaka
Shinsaku Kobayashi
Muneharu Mizukai
Kazuo Tomita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP1203979A priority Critical patent/JPS55104274A/en
Publication of JPS55104274A publication Critical patent/JPS55104274A/en
Pending legal-status Critical Current

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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:An isoxazolin-3-one derivative of formula I (R2 is lower alkyl or lower alkenyl; R2 is lowe alkyl or aryl; X is H, lowr alkyl, lower alkoxy, or halogen).
EXAMPLE: 2-Allyl-4-phenyl-5-methyl-4-isoxazolin-3-one.
USE: Medicine having antiphlogistic, analgesic, and antipyretic activities. For oral or rectal administration.
PROCESS: The compound of formula I is prepared by reacting a 3-hydroxyisoxazole compound of formula II with a halogen compound of formula R1-Y (Y is halogen) in an inert solvent, at 0W150°C, pref. 20W130°C.
COPYRIGHT: (C)1980,JPO&Japio
JP1203979A 1979-02-05 1979-02-05 Isoxazolin-3-one derivative and its preparation Pending JPS55104274A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1203979A JPS55104274A (en) 1979-02-05 1979-02-05 Isoxazolin-3-one derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1203979A JPS55104274A (en) 1979-02-05 1979-02-05 Isoxazolin-3-one derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS55104274A true JPS55104274A (en) 1980-08-09

Family

ID=11794452

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1203979A Pending JPS55104274A (en) 1979-02-05 1979-02-05 Isoxazolin-3-one derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS55104274A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0273744A2 (en) * 1986-12-26 1988-07-06 Sankyo Company Limited Centrally-acting muscle relaxants
US5071994A (en) * 1987-02-05 1991-12-10 Fuji Photo Film Co., Ltd. 2-aryl-4-halomethyl-4-isoxazolin-3-one derivatives
US5221750A (en) * 1987-02-05 1993-06-22 Fuji Photo Film Co., Ltd. 2-aryl-4-isoxazolin-3-one derivatives

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0273744A2 (en) * 1986-12-26 1988-07-06 Sankyo Company Limited Centrally-acting muscle relaxants
US5071994A (en) * 1987-02-05 1991-12-10 Fuji Photo Film Co., Ltd. 2-aryl-4-halomethyl-4-isoxazolin-3-one derivatives
US5221750A (en) * 1987-02-05 1993-06-22 Fuji Photo Film Co., Ltd. 2-aryl-4-isoxazolin-3-one derivatives

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