JPS5466653A - Novel p-aminophenylacetic acid derivative, its preparation, and pharmaceurtical composition containing said derivative as effective component - Google Patents
Novel p-aminophenylacetic acid derivative, its preparation, and pharmaceurtical composition containing said derivative as effective componentInfo
- Publication number
- JPS5466653A JPS5466653A JP13233877A JP13233877A JPS5466653A JP S5466653 A JPS5466653 A JP S5466653A JP 13233877 A JP13233877 A JP 13233877A JP 13233877 A JP13233877 A JP 13233877A JP S5466653 A JPS5466653 A JP S5466653A
- Authority
- JP
- Japan
- Prior art keywords
- derivative
- pharmaceurtical
- novel
- preparation
- composition containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A compound of formula I [A is II (R4-6 are H, alkylk, alkoxy, halogen, etc,. Y' is H, lower alkyl, lower alkoxy, halogen); III (R13 is H, alkyl; R14 is alkyl, alkoxy, phenoxy, etc.; Y2 is H, F, CI.); IV (n is an integer of 1-4); R2,3 are H, lower alkyl; X is H, lower alkyl, l lower alkoxy, halogen; R1 is H, alkyl, -CH2CH(OH)CH2OH, etc.].
EXAMPLE: 4-[2-Anilinobenzamide]phenylacetic acid.
USE: Antipyretic, analgesic and antiphlogistic agent.
PROCESS: The objective compound I is prepared by reacting the compound V (pref. acid halogenide) with the compound VI (R1 is H, lower alkyl) in the presence of a base (triethylamine, etc.) at 0-50°C.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13233877A JPS5466653A (en) | 1977-11-04 | 1977-11-04 | Novel p-aminophenylacetic acid derivative, its preparation, and pharmaceurtical composition containing said derivative as effective component |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13233877A JPS5466653A (en) | 1977-11-04 | 1977-11-04 | Novel p-aminophenylacetic acid derivative, its preparation, and pharmaceurtical composition containing said derivative as effective component |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5466653A true JPS5466653A (en) | 1979-05-29 |
Family
ID=15078988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13233877A Pending JPS5466653A (en) | 1977-11-04 | 1977-11-04 | Novel p-aminophenylacetic acid derivative, its preparation, and pharmaceurtical composition containing said derivative as effective component |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5466653A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6346242B1 (en) * | 1995-03-31 | 2002-02-12 | Emishpere Technologies, Inc. | Compounds and compositions for delivering active agents |
| CN115108931A (en) * | 2022-04-02 | 2022-09-27 | 南华大学附属第一医院 | Tofenamic acid derivative and preparation and application thereof |
-
1977
- 1977-11-04 JP JP13233877A patent/JPS5466653A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6346242B1 (en) * | 1995-03-31 | 2002-02-12 | Emishpere Technologies, Inc. | Compounds and compositions for delivering active agents |
| CN115108931A (en) * | 2022-04-02 | 2022-09-27 | 南华大学附属第一医院 | Tofenamic acid derivative and preparation and application thereof |
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