JPS5625166A - 5-fluorouracil derivative - Google Patents

5-fluorouracil derivative

Info

Publication number
JPS5625166A
JPS5625166A JP10074179A JP10074179A JPS5625166A JP S5625166 A JPS5625166 A JP S5625166A JP 10074179 A JP10074179 A JP 10074179A JP 10074179 A JP10074179 A JP 10074179A JP S5625166 A JPS5625166 A JP S5625166A
Authority
JP
Japan
Prior art keywords
formula
fluorouracil
compound
fluorouracil derivative
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10074179A
Other languages
Japanese (ja)
Inventor
Hiroshi Fukatsu
Akira Okura
Tetsuji Miyano
Ikuo Iwatsuki
Ikuo Matsumoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD KK
Original Assignee
Banyu Phamaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Phamaceutical Co Ltd filed Critical Banyu Phamaceutical Co Ltd
Priority to JP10074179A priority Critical patent/JPS5625166A/en
Publication of JPS5625166A publication Critical patent/JPS5625166A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:5-Fluorouracil derivatives of formula I (R is H, lower alkyl, preferably H and ethyl).
EXAMPLE: The compound of formula II.
USE: Anticarcinostatic agent.
PREPARATION: After the reaction of 5-fluorouracil with phosgen, the reaction product is made to react with a phenylglycine derivative of formula III. When necessary, the ester linkage in the product is hydrolyzed to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP10074179A 1979-08-09 1979-08-09 5-fluorouracil derivative Pending JPS5625166A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10074179A JPS5625166A (en) 1979-08-09 1979-08-09 5-fluorouracil derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10074179A JPS5625166A (en) 1979-08-09 1979-08-09 5-fluorouracil derivative

Publications (1)

Publication Number Publication Date
JPS5625166A true JPS5625166A (en) 1981-03-10

Family

ID=14281978

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10074179A Pending JPS5625166A (en) 1979-08-09 1979-08-09 5-fluorouracil derivative

Country Status (1)

Country Link
JP (1) JPS5625166A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5663966A (en) * 1979-10-29 1981-05-30 Tokyo Kinzoku Kogyo Kk Pyrimidine derivative and its preparation
US4636508A (en) * 1985-04-22 1987-01-13 Uniroyal Chemical Company, Inc. 5-pyrimidinecarboxyamides and treatment of leukemia therewith

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5663966A (en) * 1979-10-29 1981-05-30 Tokyo Kinzoku Kogyo Kk Pyrimidine derivative and its preparation
US4636508A (en) * 1985-04-22 1987-01-13 Uniroyal Chemical Company, Inc. 5-pyrimidinecarboxyamides and treatment of leukemia therewith

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