JPS5625166A - 5-fluorouracil derivative - Google Patents
5-fluorouracil derivativeInfo
- Publication number
- JPS5625166A JPS5625166A JP10074179A JP10074179A JPS5625166A JP S5625166 A JPS5625166 A JP S5625166A JP 10074179 A JP10074179 A JP 10074179A JP 10074179 A JP10074179 A JP 10074179A JP S5625166 A JPS5625166 A JP S5625166A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- fluorouracil
- compound
- fluorouracil derivative
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:5-Fluorouracil derivatives of formula I (R is H, lower alkyl, preferably H and ethyl).
EXAMPLE: The compound of formula II.
USE: Anticarcinostatic agent.
PREPARATION: After the reaction of 5-fluorouracil with phosgen, the reaction product is made to react with a phenylglycine derivative of formula III. When necessary, the ester linkage in the product is hydrolyzed to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10074179A JPS5625166A (en) | 1979-08-09 | 1979-08-09 | 5-fluorouracil derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10074179A JPS5625166A (en) | 1979-08-09 | 1979-08-09 | 5-fluorouracil derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5625166A true JPS5625166A (en) | 1981-03-10 |
Family
ID=14281978
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10074179A Pending JPS5625166A (en) | 1979-08-09 | 1979-08-09 | 5-fluorouracil derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5625166A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5663966A (en) * | 1979-10-29 | 1981-05-30 | Tokyo Kinzoku Kogyo Kk | Pyrimidine derivative and its preparation |
US4636508A (en) * | 1985-04-22 | 1987-01-13 | Uniroyal Chemical Company, Inc. | 5-pyrimidinecarboxyamides and treatment of leukemia therewith |
-
1979
- 1979-08-09 JP JP10074179A patent/JPS5625166A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5663966A (en) * | 1979-10-29 | 1981-05-30 | Tokyo Kinzoku Kogyo Kk | Pyrimidine derivative and its preparation |
US4636508A (en) * | 1985-04-22 | 1987-01-13 | Uniroyal Chemical Company, Inc. | 5-pyrimidinecarboxyamides and treatment of leukemia therewith |
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